Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8FV29

Entry ID Method Resolution Chain Position Source
AF-Q8FV29-F1 Predicted AlphaFoldDB

No variants for Q8FV29

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8FV29

No associated diseases with Q8FV29

3 regional properties for Q8FV29

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 5 - 386 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 387 - 585 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 389 - 585 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MENKRNFFIT IALSILILAL WQVFYLGPKT EAQREQARIE EQQRQAQQAA QNRQASSSTG
70 80 90 100 110 120
DTPQMPANPD SIPGQGDTKA AGAPLTRDAA IAQSPRIEID TPSLRGSINL TGARLDDLYL
130 140 150 160 170 180
KKYHETVSDK SPEIELLAPS SLKQGYFVEL GFTGNDATGA VPGPNTVWVV EGNNKLTPST
190 200 210 220 230 240
PVTLTYTNDK NLTFKRVISV DDAYMFTVDD TIINNGGSTV SLASYGRVTR FNQPEHASAT
250 260 270 280 290 300
YVLHEGLIGV MGQDGLQEIK YAKIKDNKDI SFKDVIGGWV GITDKYWAAT LIPPQDEKFT
310 320 330 340 350 360
GRFSHFTNDR PRYQSDLLSA PLTVAPGQSQ KIQNRVFAGA KVVNTIQNYE TKYHIKQFDL
370 380 390 400 410 420
LIDWGWFYFI TKPMFYLIDW IYKFTGNFGV AILVVTVLLK ALFFPLANKS YKSMARMKLM
430 440 450 460 470 480
QPKMTEIREK YADDKMKQQQ AMMELYKREK INPLAGCWPV LVQIPVFFAL YKVLYVTIEM
490 500 510 520 530 540
RHAPFFGWIQ DLAAPDPTSI FNLFGLLPYT VPHFLMIGVW PIIMGITMFL QMRMNPTPPD
550 560 570 580 590 600
PTQAAIFTWM PIIFTFMLAS FPAGLVIYWA WNNTLSIIQQ SVIMKRQGVK IELFDNLKGL
FRRKPKEANK