Q8FFC0

PR
Gene name
zipA
Protein name
Cell division protein ZipA
Names
Species
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
KEGG Pathway
ecc:c2946
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-220 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8FFC0

Entry ID Method Resolution Chain Position Source
AF-Q8FFC0-F1 Predicted AlphaFoldDB

No variants for Q8FFC0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8FFC0

No associated diseases with Q8FFC0

10 regional properties for Q8FFC0

Type Name Position InterPro Accession
domain Protein kinase domain 92 - 354 IPR000719
domain AGC-kinase, C-terminal 357 - 425 IPR000961
domain Pleckstrin homology domain 1150 - 1351 IPR001849
domain Protein kinase C-like, phorbol ester/diacylglycerol-binding domain 1260 - 1315 IPR002219
active_site Serine/threonine-protein kinase, active site 210 - 222 IPR008271
domain HR1 rho-binding domain 497 - 573 IPR011072
domain ROCK, Rho binding domain 978 - 1047 IPR015008
binding_site Protein kinase, ATP binding site 98 - 121 IPR017441
domain Rho-associated protein kinase 2, catalytic domain 39 - 417 IPR029878
domain Rho-associated protein kinase 2, HR1 domain 505 - 571 IPR037311

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass type I membrane protein
  • Localizes to the Z ring in an FtsZ-dependent manner
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cell septum assembly The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMQDLRLILI IVGAIAIIAL LVHGFWTSRK ERSSMFRDRP LKRMKSKRDD DSYDEDVEDD
70 80 90 100 110 120
EGVGEVRVHR VNHAPANAQE HEAARPSPQH QYQPPYASAQ PRQPVQQPPE AQVPPQHAPR
130 140 150 160 170 180
PTQPVQQPVQ QPAYQPQPEQ PLQQPVSPQV ASAPQPVHSA PQPAQQAFQP AEPVAAPQPE
190 200 210 220 230 240
PVAEPAPVMD KPKRKEAVII MNVAAHHGSE LNGELLLNSI QQAGFIFGDM NIYHRHLSPD
250 260 270 280 290 300
GSGPALFSLA NMVKPGTFDP EMKDFTTPGV TIFMQVPSYG DELQNFKLML QSAQHIADEV
310 320 330
GGVVLDDQRR MMTPQKLREY QDIIREVKDA NA