Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8ED69

Entry ID Method Resolution Chain Position Source
AF-Q8ED69-F1 Predicted AlphaFoldDB

No variants for Q8ED69

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8ED69

No associated diseases with Q8ED69

5 regional properties for Q8ED69

Type Name Position InterPro Accession
domain FCH domain 17 - 105 IPR001060
domain SH3 domain 385 - 444 IPR001452
domain F-BAR domain 13 - 283 IPR031160
domain PACSIN1/PACSIN2, SH3 domain 388 - 443 IPR035743
domain PACSIN1, F-BAR 19 - 276 IPR037454

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass type I membrane protein
  • Localizes to the Z ring in an FtsZ-dependent manner
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
division septum assembly The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDLQLVLFV LGAIAIVAVL VHGFWSIRRQ QPKSLKDSPM GNFYKKQAER GEAAPAPKRV
70 80 90 100 110 120
DAEGFDSDGI GAVRVRKASE SQTPEAPAVN PYLKQEAKVE PQIEPKPQFK QEPSMAQPDF
130 140 150 160 170 180
SLQSPSVDEP HRGTKASRQE PVLKSNTAHL NQEHAGQSHA AMVAQKVAEE QRAQVQKPTQ
190 200 210 220 230 240
TALFDDEVYQ EQQPQAVEEA PETEESLGEP RDVLVLHVVA KEGQQLNGAE LLPCFLTLNF
250 260 270 280 290 300
KYGDMNIFHR HVDNAGNGKV LFSIANMVKP GVFDPDNMEQ FSTLGVVFFM TLPCYGDALM
310 320 330 340
NFSIMLNSAR QLADDIDAVV LDGQRQPWGE FTKQDYLHRI RANA