Q8DN93

PR
Gene name
yidC2
Protein name
Membrane protein insertase YidC 2
Names
Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2
Species
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
KEGG Pathway
spr:spr1852
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

224-276 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8DN93

Entry ID Method Resolution Chain Position Source
AF-Q8DN93-F1 Predicted AlphaFoldDB

No variants for Q8DN93

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8DN93

No associated diseases with Q8DN93

2 regional properties for Q8DN93

Type Name Position InterPro Accession
domain Membrane insertase YidC/Oxa/ALB, C-terminal 59 - 243 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 61 - 243 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

2 GO annotations of biological process

Name Definition
protein insertion into membrane The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGVKKKLKLT SLLGLSLLIM TACATNGVTS DITAESADFW SKLVYFFAEI IRFLSFDISI
70 80 90 100 110 120
GVGIILFTVL IRTVLLPVFQ VQMVASRKMQ EAQPRIKALR EQYPGRDMES RTKLEQEMRK
130 140 150 160 170 180
VFKEMGVRQS DSLWPILIQM PVILALFQAL SRVDFLKTGH FLWINLGSVD TTLVLPILAA
190 200 210 220 230 240
VFTFLSTWLS NKALSERNGA TTAMMYGIPV LIFIFAVYAP GGVALYWTVS NAYQVLQTYF
250 260 270
LNNPFKIIAE REAVVQAQKD LENRKRKAKK KAQKTK