Q8BGB5

PR
Gene name
Limd2
Protein name
LIM domain-containing protein 2
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:67803
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-64 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8BGB5

Entry ID Method Resolution Chain Position Source
AF-Q8BGB5-F1 Predicted AlphaFoldDB

2 variants for Q8BGB5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389185495 49 Y>N No EVA
rs251662775 127 T>M No EVA

No associated diseases with Q8BGB5

2 regional properties for Q8BGB5

Type Name Position InterPro Accession
domain Zinc finger, LIM-type 39 - 99 IPR001781
domain LIMD2, LIM domain 41 - 93 IPR044115

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Mainly found in cytoplasm, concentrated in membrane ruffles and in streaks reminiscent of focal adhesion plaques
  • Also found in nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
F1MH07 MICAL1 [F-actin]-monooxygenase MICAL1 Bos taurus (Bovine) SS
Q8TDZ2 MICAL1 [F-actin]-monooxygenase MICAL1 Homo sapiens (Human) EV
Q9BT23 LIMD2 LIM domain-containing protein 2 Homo sapiens (Human) PR
Q8VDP3 Mical1 [F-actin]-monooxygenase MICAL1 Mus musculus (Mouse) EV
Q9ERG0 Lima1 LIM domain and actin-binding protein 1 Mus musculus (Mouse) PR
D3ZBP4 Mical1 [F-actin]-monooxygenase MICAL1 Rattus norvegicus (Rat) SS
10 20 30 40 50 60
MFQAAGAAQA TPSHEAKGSS GSSTVQRSKS FSLRAQVKET CAACQKTVYP MERLVADKLI
70 80 90 100 110 120
FHNSCFCCKH CHTKLSLGSY AAMHGEFYCR PHFQQLFKSK GNYDEGFGRK QHKELWAHKE
VDSGTKTA