Q86UN2
PR
Gene name |
RTN4RL1 |
Protein name |
Reticulon-4 receptor-like 1 |
Names |
Nogo receptor-like 2, Nogo-66 receptor homolog 2, Nogo-66 receptor-related protein 3, NgR3 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:146760 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q86UN2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q86UN2-F1 | Predicted | AlphaFoldDB |
366 variants for Q86UN2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA397600873 rs1394502457 |
3 | R>C | No |
ClinGen gnomAD |
|
|
rs751319746 CA8276750 |
3 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276751 rs751319746 |
3 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1007760321 CA286868954 |
4 | K>E | No |
ClinGen TOPMed |
|
|
rs1377763390 CA397600864 |
5 | G>R | No |
ClinGen gnomAD |
|
|
CA397584430 rs1228214533 |
6 | C>R | No |
ClinGen TOPMed |
|
|
CA397584417 rs1302375382 |
7 | C>R | No |
ClinGen TOPMed |
|
|
CA397584413 rs751646002 |
7 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276724 COSM976324 rs751646002 |
7 | C>Y | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs766551919 CA8276723 |
9 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA8276722 rs763186876 |
10 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772848901 CA8276721 |
14 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs999368946 CA286838781 |
17 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA397584337 rs1190786066 |
17 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs761638112 CA8276719 |
18 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA286838765 rs1044331632 |
22 | G>D | No |
ClinGen Ensembl |
|
|
rs1337210237 CA397583904 |
24 | G>S | No |
ClinGen gnomAD |
|
|
rs1194084375 CA397583887 |
26 | P>L | No |
ClinGen TOPMed |
|
|
rs746476813 CA8276716 |
27 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs150719821 CA8276717 |
27 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397583865 rs1225720410 |
30 | V>M | No |
ClinGen gnomAD |
|
| TCGA novel | 31 | C>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1326974609 CA397583838 |
33 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs530944036 CA8276712 |
34 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA286838728 rs889815822 |
37 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA397583789 rs1567846806 |
41 | Q>E | No |
ClinGen Ensembl |
|
|
rs755513471 CA8276708 |
42 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs758542113 CA8276705 |
46 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs750712981 CA8276704 |
47 | A>S | No |
ClinGen ExAC |
|
|
rs1251335399 CA397583731 |
49 | P>L | No |
ClinGen gnomAD |
|
| TCGA novel | 50 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs764072507 CA8276700 |
54 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs528290556 CA8276699 |
56 | S>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8276697 rs771775825 |
57 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs745495757 CA8276696 |
58 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3378097 CA8276695 rs773997178 |
58 | R>H | pancreas [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1355844566 CA397583670 |
59 | V>A | No |
ClinGen gnomAD |
|
|
CA8276693 rs748509266 |
59 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1326264318 CA397583654 |
62 | Q>K | No |
ClinGen gnomAD |
|
|
rs940194213 CA286838632 |
65 | R>C | No |
ClinGen TOPMed |
|
|
CA8276692 rs375704646 |
65 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397583626 rs1375961303 |
66 | I>V | No |
ClinGen gnomAD |
|
|
CA286838627 rs866759895 |
67 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA8276691 rs201050462 |
67 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs780091628 CA8276689 |
68 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1190764448 CA397583593 |
70 | Q>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 71 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 72 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8276684 rs753662485 |
72 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8276682 rs760687232 |
73 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs368720546 CA8276683 |
73 | H>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397583530 rs1213485252 |
74 | F>V | No |
ClinGen gnomAD |
|
|
rs1346083755 CA397583507 |
75 | S>N | No |
ClinGen gnomAD |
|
|
CA397583477 rs1434847531 |
77 | A>G | No |
ClinGen TOPMed |
|
|
rs759023275 CA8276679 |
77 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA8276678 rs773768549 |
78 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA397583467 rs1375042415 |
78 | M>V | No |
ClinGen gnomAD |
|
|
rs770571252 CA8276677 |
79 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA397583432 rs1356039622 |
81 | L>V | No |
ClinGen gnomAD |
|
| TCGA novel | 82 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs938966669 CA286838513 |
83 | I>M | No |
ClinGen TOPMed gnomAD |
|
|
CA286838520 rs969935626 |
83 | I>V | No |
ClinGen TOPMed |
|
|
CA397583361 rs1432638757 |
85 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
CA397583362 rs1432638757 |
85 | S>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs776972213 CA8276675 |
87 | N>D | No |
ClinGen ExAC |
|
|
rs1292008068 CA397583327 |
87 | N>I | No |
ClinGen TOPMed |
|
|
rs1292008068 CA397583329 |
87 | N>S | No |
ClinGen TOPMed |
|
|
CA8276673 rs747383114 |
90 | Y>S | No |
ClinGen ExAC gnomAD |
|
|
rs1175577569 CA397583268 |
93 | P>A | No |
ClinGen gnomAD |
|
|
CA397583266 rs1175577569 |
93 | P>T | No |
ClinGen gnomAD |
|
|
CA8276670 rs542339526 |
97 | E>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs778906681 CA8276668 |
100 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1179517958 CA397583166 |
108 | G>S | No |
ClinGen TOPMed |
|
|
rs11652394 CA286838357 |
111 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8276664 rs11652394 |
111 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8276665 rs372360468 |
111 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8276661 rs368763192 |
114 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8276662 rs767452609 |
114 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276660 rs563257746 |
115 | T>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs375151899 CA286838321 |
116 | L>V | No |
ClinGen ESP |
|
| TCGA novel | 119 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs769437102 CA8276656 |
119 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276654 rs372074978 |
124 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs772608395 CA8276653 |
125 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA397583020 rs1274542991 |
131 | Y>C | No |
ClinGen gnomAD |
|
|
CA8276650 rs770975627 |
132 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1359687529 CA397582985 |
136 | G>E | No |
ClinGen gnomAD |
|
|
rs778075693 CA8276648 |
136 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs756440405 CA286838211 |
139 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756440405 CA8276647 |
139 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397582959 rs1434711147 |
140 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA8276646 rs752496885 |
141 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276643 rs377049572 |
143 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1171656450 CA397582943 |
143 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA8276641 COSM1318534 rs373384654 |
144 | V>I | Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 145 | F>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8276636 rs199769480 |
146 | G>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276635 rs199769480 |
146 | G>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276639 rs201429067 |
146 | G>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276638 rs201429067 |
146 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8276637 rs199769480 |
146 | G>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276631 rs567714935 |
147 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
RCV000954999 CA8276632 rs181444163 |
147 | G>S | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA397582916 rs1276589062 |
149 | H>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1229011453 CA397582912 |
149 | H>Q | No |
ClinGen gnomAD |
|
|
CA397582915 rs1276589062 |
149 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
CA397582906 rs1296650374 |
150 | S>I | No |
ClinGen gnomAD |
|
|
rs1234702308 CA397582898 |
152 | Q>K | No |
ClinGen gnomAD |
|
|
rs779811649 CA8276625 |
160 | H>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1464011443 CA397582831 |
161 | I>V | No |
ClinGen gnomAD |
|
|
CA8276623 rs749912127 |
162 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA397582809 rs1220560112 |
164 | L>V | No |
ClinGen TOPMed |
|
|
rs367650638 CA286838013 |
166 | D>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA286838007 rs375946051 |
167 | D>N | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs756897330 CA8276621 |
168 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs763822561 CA8276619 |
170 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA397582759 rs1178400594 |
171 | D>A | No |
ClinGen gnomAD |
|
|
CA397582754 rs1249260804 |
172 | L>V | No |
ClinGen TOPMed |
|
|
CA397582716 rs1273767304 |
177 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA397582713 rs1211351597 |
178 | L>V | No |
ClinGen gnomAD |
|
|
rs766947257 CA8276616 |
182 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA8276614 rs368659161 |
184 | K>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs770068855 CA8276613 |
184 | K>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 186 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8276612 rs375476494 |
186 | W>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs776647226 CA8276611 |
189 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA8276610 rs190874588 |
190 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397582583 rs1171163904 |
192 | T>I | No |
ClinGen gnomAD |
|
|
CA397582592 rs1597483661 |
192 | T>P | No |
ClinGen Ensembl |
|
|
CA286837882 rs888531814 |
194 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs745871325 CA8276606 |
194 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA397582550 rs1432751867 |
195 | G>A | No |
ClinGen TOPMed |
|
|
CA397582552 rs1432751867 |
195 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1188658733 CA397582539 |
196 | L>P | No |
ClinGen gnomAD |
|
|
CA286837859 rs1049843718 |
198 | N>K | No |
ClinGen Ensembl |
|
|
rs571713611 CA8276605 |
198 | N>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 201 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA397582439 rs1234981520 |
206 | E>K | No |
ClinGen TOPMed |
|
|
rs1597483617 CA397582421 |
207 | N>T | No |
ClinGen Ensembl |
|
|
CA397582378 rs1241277953 |
210 | Q>R | No |
ClinGen gnomAD |
|
|
CA397582364 rs1327241332 |
211 | W>* | No |
ClinGen gnomAD |
|
|
rs1254742014 CA397582346 |
212 | V>A | No |
ClinGen Ensembl |
|
|
rs1287793641 CA397582353 |
212 | V>I | No |
ClinGen gnomAD |
|
|
CA397582320 rs1357881333 |
214 | H>Q | No |
ClinGen gnomAD |
|
|
rs1415990553 CA397582327 |
214 | H>Y | No |
ClinGen gnomAD |
|
|
rs1209471146 CA397582294 |
216 | A>V | No |
ClinGen TOPMed |
|
|
CA8276600 rs751851270 |
217 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs755814532 CA8276601 |
217 | F>V | No |
ClinGen ExAC gnomAD |
|
|
rs1159873255 CA397582281 |
218 | H>N | No |
ClinGen gnomAD |
|
|
rs1597483577 CA397582260 |
219 | D>A | No |
ClinGen Ensembl |
|
|
rs773917232 CA8276597 |
219 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs763553016 CA8276598 |
219 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1476172192 CA397582245 |
221 | R>C | No |
ClinGen gnomAD |
|
|
rs200262350 CA8276595 COSM1381264 |
221 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs200262350 CA8276596 |
221 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8276594 rs776790977 |
222 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1447294066 CA397582227 |
224 | T>I | No |
ClinGen gnomAD |
|
|
CA397582226 rs1597483559 |
225 | T>P | No |
ClinGen Ensembl |
|
|
rs1263575616 CA397582188 |
230 | N>S | No |
ClinGen gnomAD |
|
|
CA8276593 rs768735130 |
231 | N>T | No |
ClinGen ExAC gnomAD |
|
|
rs1463694782 CA397582175 |
232 | S>G | No |
ClinGen gnomAD |
|
|
rs1233932883 CA397582164 |
232 | S>R | No |
ClinGen gnomAD |
|
|
CA8276592 rs565712676 |
232 | S>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1037263311 CA286837774 |
234 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1327457813 CA397582079 |
238 | G>S | No |
ClinGen gnomAD |
|
|
CA397582030 rs1480220740 |
240 | C>F | No |
ClinGen TOPMed |
|
|
rs1480220740 CA397582034 |
240 | C>Y | No |
ClinGen TOPMed |
|
|
rs1432516691 CA397582013 |
242 | A>T | No |
ClinGen gnomAD |
|
|
CA8276589 rs187193472 |
243 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs771911042 CA8276590 |
243 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs778757018 CA8276588 |
245 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397581956 rs1447923264 |
246 | A>G | No |
ClinGen gnomAD |
|
|
rs748698371 CA8276586 |
246 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA397581940 rs1214414435 |
248 | E>K | No |
ClinGen gnomAD |
|
|
rs1209830884 CA397581891 |
251 | R>C | No |
ClinGen gnomAD |
|
|
CA397581889 rs1340653930 |
251 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
rs761755972 CA8276582 |
254 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276581 rs761755972 |
254 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA286837705 rs1042055508 |
256 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
CA8276580 rs202235318 |
256 | P>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA286837702 rs202235318 |
256 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1042055508 CA397581797 |
256 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1322280183 CA397581753 |
258 | D>G | No |
ClinGen gnomAD |
|
|
rs1398493778 CA397581705 |
260 | G>C | No |
ClinGen gnomAD |
|
|
CA397581703 rs1253673804 |
260 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
rs1428802231 CA397581673 |
262 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs753828517 CA8276577 |
262 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA286837676 rs753828517 |
262 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276575 rs760795037 COSM270087 |
263 | A>T | large_intestine endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs201739711 CA8276574 |
263 | A>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397581649 rs1438935737 |
264 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA397581651 rs1438935737 |
264 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA286837634 rs1031533787 |
264 | R>H | No |
ClinGen gnomAD |
|
|
CA397581630 rs1369024141 |
266 | L>M | No |
ClinGen TOPMed |
|
|
CA8276570 rs770752769 |
267 | W>L | No |
ClinGen ExAC gnomAD |
|
|
rs1281492760 CA397581576 |
269 | W>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA397581586 rs1161263898 |
269 | W>S | No |
ClinGen TOPMed |
|
|
CA8276569 rs749290685 |
271 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA286837612 rs563774766 |
272 | R>K | No |
ClinGen 1000Genomes gnomAD |
|
|
CA8276568 rs777146216 |
272 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA397581521 rs1337468366 |
273 | F>L | No |
ClinGen gnomAD |
|
|
rs769407342 CA8276567 |
274 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA286837609 rs772099286 |
274 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA286837600 rs966393829 |
275 | G>C | No |
ClinGen Ensembl |
|
|
CA8276565 rs780947741 |
279 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1423263163 CA397581421 |
281 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1172094131 CA397581416 |
282 | C>Y | No |
ClinGen gnomAD |
|
|
rs750791987 CA8276563 |
284 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA286837598 rs750791987 |
284 | S>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779372066 CA8276562 |
285 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1567846136 CA397581358 |
286 | G>R | No |
ClinGen Ensembl |
|
|
CA8276558 rs760742955 |
288 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276559 rs764521112 |
288 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1282798398 CA397581319 |
289 | H>D | No |
ClinGen TOPMed |
|
|
CA397581295 rs376570696 |
290 | G>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs376570696 CA8276556 |
290 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397581279 rs1223864647 |
291 | Q>* | No |
ClinGen gnomAD |
|
|
rs1597483348 CA397581251 |
292 | D>E | No |
ClinGen Ensembl |
|
|
rs1285903874 CA397581264 |
292 | D>N | No |
ClinGen gnomAD |
|
|
rs1355983520 CA397581239 |
293 | L>P | No |
ClinGen gnomAD |
|
|
rs958891088 CA286837537 |
297 | R>T | No |
ClinGen TOPMed |
|
|
rs1170248199 CA397581163 |
299 | E>G | No |
ClinGen TOPMed |
|
|
CA8276550 rs369588207 |
299 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA397581171 rs369588207 |
299 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs199947070 CA8276548 |
302 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276549 rs747609277 |
302 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs768388911 CA8276547 |
305 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397581069 rs768388911 |
305 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276545 rs779131079 |
306 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA8276544 rs757583703 |
307 | P>A | No |
ClinGen ExAC |
|
|
CA8276543 rs557485708 |
308 | A>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
RCV000961450 CA8276542 rs77488612 |
308 | A>V | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA397581015 rs1216145496 |
310 | P>L | No |
ClinGen gnomAD |
|
|
CA8276538 rs755191284 |
311 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755191284 CA397581003 |
311 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751839922 CA8276537 |
312 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs762746649 CA8276535 |
313 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs766528091 CA8276536 |
313 | I>S | No |
ClinGen ExAC gnomAD |
|
|
rs772901845 CA8276534 |
315 | S>T | No |
ClinGen ExAC |
|
|
CA397580938 rs1226525547 |
316 | H>Y | No |
ClinGen gnomAD |
|
|
CA8276533 rs765195768 |
317 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765195768 CA286837380 COSM3691406 |
317 | T>M | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs866035248 CA286837364 |
318 | L>F | No |
ClinGen Ensembl |
|
| TCGA novel | 319 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1597483276 CA397580897 |
319 | T>P | No |
ClinGen Ensembl |
|
|
CA8276529 rs746529932 |
320 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA8276527 rs572459222 |
322 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8276528 rs572459222 |
322 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276526 rs749616876 |
323 | R>S | No |
ClinGen ExAC gnomAD |
|
|
rs1413573820 CA397580842 |
324 | A>S | No |
ClinGen gnomAD |
|
|
CA286837352 rs868360880 |
324 | A>V | No |
ClinGen Ensembl |
|
|
CA8276524 rs189434887 |
325 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276523 rs189434887 |
325 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397580821 rs1245771951 |
325 | A>V | No |
ClinGen gnomAD |
|
|
rs771199574 CA8276522 |
326 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8276521 rs535637325 |
326 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397580807 rs535637325 |
326 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs751599612 CA8276520 |
329 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs911804844 CA397580742 |
330 | H>L | No |
ClinGen gnomAD |
|
|
CA397580738 rs1427559014 |
330 | H>Q | No |
ClinGen TOPMed |
|
|
rs911804844 CA286837259 |
330 | H>R | No |
ClinGen gnomAD |
|
|
CA8276519 rs375350984 |
331 | S>P | No |
ClinGen ESP ExAC gnomAD |
|
|
CA286837249 rs375350984 |
331 | S>T | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1230291799 CA397580720 |
332 | P>H | No |
ClinGen gnomAD |
|
|
CA397580715 rs1230291799 |
332 | P>L | No |
ClinGen gnomAD |
|
| TCGA novel | 332 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs750199465 CA8276517 |
333 | H>D | No |
ClinGen ExAC gnomAD |
|
|
CA397580695 rs1434630113 |
333 | H>R | No |
ClinGen gnomAD |
|
|
rs991614274 CA286837234 |
334 | G>A | No |
ClinGen TOPMed gnomAD |
|
|
CA397580679 rs991614274 |
334 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
CA8276515 rs761826663 |
334 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 338 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA397580600 rs1437939279 |
340 | G>S | No |
ClinGen TOPMed |
|
|
CA397580591 rs1431939183 |
340 | G>V | No |
ClinGen gnomAD |
|
|
CA286837231 rs958778541 |
341 | H>Y | No |
ClinGen TOPMed |
|
|
CA8276511 rs774885649 |
342 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760221532 CA8276512 |
342 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs770204500 CA8276507 |
344 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1390218073 CA397580527 |
345 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA8276506 rs748528237 |
345 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs143202933 CA8276504 |
346 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8276505 rs148191398 |
346 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs376372113 CA8276501 |
348 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8276500 rs750666647 |
350 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA397580494 rs1367517650 |
351 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA286837176 rs770067596 |
352 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1241384322 CA397580482 |
353 | G>E | No |
ClinGen gnomAD |
|
|
CA8276498 rs757043706 |
353 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 354 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1434976161 CA397580477 |
354 | K>R | No |
ClinGen gnomAD |
|
|
rs1013199849 CA286837145 |
358 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA8276495 rs760577801 |
362 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752222188 CA8276494 |
362 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397580420 rs752222188 |
362 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276493 rs376728844 |
363 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 364 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA397580379 rs527297405 |
368 | A>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs527297405 CA8276492 |
368 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8276489 rs762129974 |
370 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs369151936 CA8276487 |
371 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8276486 rs747533348 |
372 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs1282146281 CA397580360 |
372 | K>Q | No |
ClinGen TOPMed |
|
|
rs1349122455 CA397580350 |
373 | Q>R | No |
ClinGen gnomAD |
|
|
rs780165972 CA8276485 |
374 | A>T | No |
ClinGen ExAC |
|
|
CA8276484 rs771985326 |
374 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA397580341 rs1403925983 |
375 | P>A | No |
ClinGen gnomAD |
|
| TCGA novel | 375 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs779236623 CA8276482 |
376 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276480 rs753664611 |
378 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA8276476 rs767505803 |
385 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA8276477 rs199704619 |
385 | Q>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs944549209 CA286837048 |
385 | Q>R | No |
ClinGen Ensembl |
|
|
rs758906669 CA8276475 |
386 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs751103843 CA8276474 |
387 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs981499143 CA286837036 |
390 | F>I | No |
ClinGen TOPMed |
|
|
rs765970850 CA8276473 |
392 | I>N | No |
ClinGen ExAC gnomAD |
|
|
CA397580212 rs1351912957 |
393 | M>I | No |
ClinGen TOPMed |
|
|
CA8276472 rs762629775 |
393 | M>R | No |
ClinGen ExAC gnomAD |
|
|
CA8276471 rs375179009 |
395 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs764420876 CA8276470 |
397 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764420876 CA286837000 |
397 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA286837011 rs953324491 |
397 | R>W | No |
ClinGen gnomAD |
|
|
CA397580192 rs1277827590 |
398 | P>T | No |
ClinGen TOPMed |
|
|
rs775791709 CA8276468 |
404 | C>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs542996365 CA397580140 |
405 | A>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs376667761 CA8276467 |
405 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs542996365 CA8276466 |
405 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs774622219 CA8276465 |
406 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs749590901 CA8276463 |
406 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749590901 CA8276464 |
406 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1366735115 CA397580135 |
407 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA397580127 rs1366554333 |
408 | T>A | No |
ClinGen gnomAD |
|
|
rs777700409 CA8276462 |
408 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA397580126 rs1366554333 |
408 | T>S | No |
ClinGen gnomAD |
|
|
rs748636006 CA286836969 |
409 | P>S | No |
ClinGen TOPMed |
|
|
CA397580123 rs748636006 |
409 | P>T | No |
ClinGen TOPMed |
|
|
CA397580114 rs1248810935 |
410 | I>T | No |
ClinGen gnomAD |
|
|
rs574165669 CA8276461 |
411 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8276460 rs563904841 |
411 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397580105 rs1182890656 |
412 | A>S | No |
ClinGen TOPMed |
|
|
rs370518676 CA8276459 |
412 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397580099 rs1211003447 |
413 | P>H | No |
ClinGen gnomAD |
|
|
rs1211003447 CA397580097 |
413 | P>L | No |
ClinGen gnomAD |
|
|
CA397580088 rs1264073646 |
415 | G>R | No |
ClinGen gnomAD |
|
| TCGA novel | 417 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1347718140 CA397580036 |
420 | S>Y | No |
ClinGen gnomAD |
|
|
rs184673082 CA8276455 |
421 | S>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1299282090 CA397579992 |
422 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1299282090 CA397579988 |
422 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA8276452 rs764945936 |
424 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1323624124 CA397579942 |
426 | G>R | No |
ClinGen gnomAD |
|
|
CA397579919 rs1407040461 |
427 | A>V | No |
ClinGen gnomAD |
|
|
CA397579901 rs1162440225 |
428 | S>F | No |
ClinGen gnomAD |
|
|
rs1391772649 CA397579885 |
429 | L>I | No |
ClinGen gnomAD |
|
|
CA397579867 rs1190825455 |
430 | L>M | No |
ClinGen gnomAD |
|
|
CA397579850 rs1241645401 |
431 | A>V | No |
ClinGen gnomAD |
|
|
CA8276449 rs534972727 |
432 | W>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1212367492 CA397579844 |
432 | W>S | No |
ClinGen TOPMed |
|
|
CA8276447 rs774569320 |
437 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8276448 rs774569320 |
437 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs749394684 CA8276445 |
438 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA397579701 rs1277201699 |
439 | T>I | No |
ClinGen gnomAD |
|
|
rs1245550664 CA397579709 |
439 | T>P | No |
ClinGen TOPMed |
|
|
CA8276443 rs770088982 |
441 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA286836830 rs903237164 |
441 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA397579655 rs903237164 |
441 | R>L | No |
ClinGen TOPMed gnomAD |
No associated diseases with Q86UN2
10 regional properties for Q86UN2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cysteine-rich flanking region, C-terminal | 255 - 305 | IPR000483 |
| repeat | Leucine-rich repeat | 101 - 171 | IPR001611-1 |
| repeat | Leucine-rich repeat | 174 - 233 | IPR001611-2 |
| repeat | Leucine-rich repeat, typical subtype | 76 - 98 | IPR003591-1 |
| repeat | Leucine-rich repeat, typical subtype | 99 - 123 | IPR003591-2 |
| repeat | Leucine-rich repeat, typical subtype | 124 - 147 | IPR003591-3 |
| repeat | Leucine-rich repeat, typical subtype | 148 - 171 | IPR003591-4 |
| repeat | Leucine-rich repeat, typical subtype | 172 - 195 | IPR003591-5 |
| repeat | Leucine-rich repeat, typical subtype | 196 - 219 | IPR003591-6 |
| repeat | Leucine-rich repeat, typical subtype | 220 - 243 | IPR003591-7 |
Functions
10 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchored component of plasma membrane | The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. |
| cell projection | A prolongation or process extending from a cell, e.g. a flagellum or axon. |
| cell surface | The external part of the cell wall and/or plasma membrane. |
| extracellular exosome | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
| extracellular matrix | A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. |
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| membrane raft | Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. |
| perikaryon | The portion of the cell soma (neuronal cell body) that excludes the nucleus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| chondroitin sulfate binding | Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). |
| heparin binding | Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. |
| signaling receptor activity | Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| axon regeneration | The regrowth of axons following their loss or damage. |
| corpus callosum development | The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. |
| negative regulation of axon regeneration | Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration. |
| negative regulation of neuron projection development | Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). |
37 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3MHH9 | ECM2 | Extracellular matrix protein 2 | Bos taurus (Bovine) | PR |
| P58874 | OPTC | Opticin | Bos taurus (Bovine) | PR |
| Q24K06 | LRRC10 | Leucine-rich repeat-containing protein 10 | Bos taurus (Bovine) | PR |
| Q9V780 | Lap1 | Protein lap1 | Drosophila melanogaster (Fruit fly) | PR |
| Q96NW7 | LRRC7 | Leucine-rich repeat-containing protein 7 | Homo sapiens (Human) | PR |
| Q8IWT6 | LRRC8A | Volume-regulated anion channel subunit LRRC8A | Homo sapiens (Human) | PR |
| Q9HCJ2 | LRRC4C | Leucine-rich repeat-containing protein 4C | Homo sapiens (Human) | PR |
| Q9UFC0 | LRWD1 | Leucine-rich repeat and WD repeat-containing protein 1 | Homo sapiens (Human) | PR |
| Q96L50 | LRR1 | Leucine-rich repeat protein 1 | Homo sapiens (Human) | PR |
| Q8IWK6 | ADGRA3 | Adhesion G protein-coupled receptor A3 | Homo sapiens (Human) | PR |
| Q7L1W4 | LRRC8D | Volume-regulated anion channel subunit LRRC8D | Homo sapiens (Human) | PR |
| Q8TDW0 | LRRC8C | Volume-regulated anion channel subunit LRRC8C | Homo sapiens (Human) | PR |
| Q38SD2 | LRRK1 | Leucine-rich repeat serine/threonine-protein kinase 1 | Homo sapiens (Human) | EV |
| Q96PB8 | LRRC3B | Leucine-rich repeat-containing protein 3B | Homo sapiens (Human) | PR |
| Q96FE5 | LINGO1 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 | Homo sapiens (Human) | PR |
| A6H694 | Lrrc63 | Leucine-rich repeat-containing protein 63 | Mus musculus (Mouse) | PR |
| Q9D9Q0 | Lrrc69 | Leucine-rich repeat-containing protein 69 | Mus musculus (Mouse) | PR |
| Q8BGI7 | Lrrc39 | Leucine-rich repeat-containing protein 39 | Mus musculus (Mouse) | PR |
| Q7TT36 | Adgra3 | Adhesion G protein-coupled receptor A3 | Mus musculus (Mouse) | PR |
| P59383 | Lrrn4 | Leucine-rich repeat neuronal protein 4 | Mus musculus (Mouse) | PR |
| Q9D1T0 | Lingo1 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 | Mus musculus (Mouse) | PR |
| Q8R502 | Lrrc8c | Volume-regulated anion channel subunit LRRC8C | Mus musculus (Mouse) | PR |
| Q80WG5 | Lrrc8a | Volume-regulated anion channel subunit LRRC8A | Mus musculus (Mouse) | PR |
| Q80TE7 | Lrrc7 | Leucine-rich repeat-containing protein 7 | Mus musculus (Mouse) | PR |
| Q5DU41 | Lrrc8b | Volume-regulated anion channel subunit LRRC8B | Mus musculus (Mouse) | PR |
| Q5RKR3 | Islr2 | Immunoglobulin superfamily containing leucine-rich repeat protein 2 | Mus musculus (Mouse) | PR |
| Q8C031 | Lrrc4c | Leucine-rich repeat-containing protein 4C | Mus musculus (Mouse) | PR |
| Q8K0S5 | Rtn4rl1 | Reticulon-4 receptor-like 1 | Mus musculus (Mouse) | PR |
| P70587 | Lrrc7 | Leucine-rich repeat-containing protein 7 | Rattus norvegicus (Rat) | PR |
| Q4V8G0 | Lrrc63 | Leucine-rich repeat-containing protein 63 | Rattus norvegicus (Rat) | PR |
| Q80WD0 | Rtn4rl1 | Reticulon-4 receptor-like 1 | Rattus norvegicus (Rat) | PR |
| Q9TZM3 | lrk-1 | Leucine-rich repeat serine/threonine-protein kinase 1 | Caenorhabditis elegans | SS |
| Q9SHI4 | RLP3 | Receptor-like protein 3 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q5G5E0 | PIRL5 | Plant intracellular Ras-group-related LRR protein 5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| B0JZ65 | lrwd1 | Leucine-rich repeat and WD repeat-containing protein 1 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q68F79 | lrrc8e | Volume-regulated anion channel subunit LRRC8E | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| B0R160 | lrwd1 | Leucine-rich repeat and WD repeat-containing protein 1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLRKGCCVEL | LLLLVAAELP | LGGGCPRDCV | CYPAPMTVSC | QAHNFAAIPE | GIPVDSERVF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LQNNRIGLLQ | PGHFSPAMVT | LWIYSNNITY | IHPSTFEGFV | HLEELDLGDN | RQLRTLAPET |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FQGLVKLHAL | YLYKCGLSAL | PAGVFGGLHS | LQYLYLQDNH | IEYLQDDIFV | DLVNLSHLFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HGNKLWSLGP | GTFRGLVNLD | RLLLHENQLQ | WVHHKAFHDL | RRLTTLFLFN | NSLSELQGEC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LAPLGALEFL | RLNGNPWDCG | CRARSLWEWL | QRFRGSSSAV | PCVSPGLRHG | QDLKLLRAED |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FRNCTGPASP | HQIKSHTLTT | TDRAARKEHH | SPHGPTRSKG | HPHGPRPGHR | KPGKNCTNPR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NRNQISKAGA | GKQAPELPDY | APDYQHKFSF | DIMPTARPKR | KGKCARRTPI | RAPSGVQQAS |
| 430 | 440 | ||||
| SASSLGASLL | AWTLGLAVTL | R |