Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q84VG1

Entry ID Method Resolution Chain Position Source
AF-Q84VG1-F1 Predicted AlphaFoldDB

No variants for Q84VG1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q84VG1

No associated diseases with Q84VG1

No regional properties for Q84VG1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q84VG1

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Endosome membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ESCRT III complex A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).
multivesicular body A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
endosome transport via multivesicular body sorting pathway The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
late endosome to vacuole transport The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5E994 CHMP1B Charged multivesicular body protein 1b Bos taurus (Bovine) PR
Q5ZKX1 CHMP1B Charged multivesicular body protein 1b Gallus gallus (Chicken) PR
Q7LBR1 CHMP1B Charged multivesicular body protein 1b Homo sapiens (Human) PR
Q9CQD4 Chmp1b2 Charged multivesicular body protein 1b-2 Mus musculus (Mouse) PR
Q99LU0 Chmp1b1 Charged multivesicular body protein 1b-1 Mus musculus (Mouse) PR
Q8LE58 CHMP1A ESCRT-related protein CHMP1A Arabidopsis thaliana (Mouse-ear cress) PR
Q9SSM4 CHMP1B ESCRT-related protein CHMP1B Arabidopsis thaliana (Mouse-ear cress) PR
Q6DF27 chmp1b Charged multivesicular body protein 1b Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q7ZVB1 chmp1b Charged multivesicular body protein 1b Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MGNPEKLMTQ IFDLKFTSKS LQRQARKCEK EEKEQKLKVK KAIEKGNMDG ARIYAENAIR
70 80 90 100 110 120
KRTEHMNYLR LASRLDAVVA RLDTQAKMQV IGKSMANIVK SLDSALATGN LQKMSETMDN
130 140 150 160 170 180
FERQFVNMEV QAEFMEGAMA GSTSLSTPET EVNSLMQQVA DDYGLEVSVG LPQAAAHAIP
190 200
AAKEKEKAVD EDDLSRRLAE LKARG