Q84JQ4

PR
Gene name
PRK2
Protein name
Pollen receptor-like kinase 2
Names
AtPRK2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G07040
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

257-335 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q84JQ4

Entry ID Method Resolution Chain Position Source
AF-Q84JQ4-F1 Predicted AlphaFoldDB

172 variants for Q84JQ4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05311076 7 M>I No 1000Genomes
ENSVATH05311075 7 M>L No 1000Genomes
ENSVATH05311077 9 V>L No 1000Genomes
tmp_2_2916652_T_C 11 I>T No 1000Genomes
ENSVATH05311078 13 S>F No 1000Genomes
ENSVATH05311078 13 S>Y No 1000Genomes
ENSVATH00214403 20 N>H No 1000Genomes
ENSVATH01684477 21 G>C No 1000Genomes
tmp_2_2916710_A_T 30 K>N No 1000Genomes
ENSVATH14103693 32 K>R No 1000Genomes
ENSVATH01684478 35 L>F No 1000Genomes
ENSVATH05311080 36 V>I No 1000Genomes
ENSVATH05311081 40 A>P No 1000Genomes
ENSVATH05311082 56 T>I No 1000Genomes
ENSVATH05311083 57 G>C No 1000Genomes
tmp_2_2916797_G_T 59 L>F No 1000Genomes
tmp_2_2916802_A_T 61 D>V No 1000Genomes
tmp_2_2916801_G_T 61 D>Y No 1000Genomes
ENSVATH05311084 62 R>K No 1000Genomes
ENSVATH05311085 64 F>I No 1000Genomes
tmp_2_2916831_G_A 71 E>K No 1000Genomes
ENSVATH11888972 76 S>F No 1000Genomes
tmp_2_2916853_C_T 78 S>F No 1000Genomes
ENSVATH00214404 80 D>N No 1000Genomes
tmp_2_2916868_C_A 83 A>E No 1000Genomes
tmp_2_2916867_G_A 83 A>T No 1000Genomes
ENSVATH00214406 88 N>K No 1000Genomes
tmp_2_2916886_C_T 89 S>F No 1000Genomes
tmp_2_2916906_A_G 96 I>V No 1000Genomes
ENSVATH05311087 100 F>L No 1000Genomes
ENSVATH05311088 101 K>E No 1000Genomes
tmp_2_2916925_G_A 102 G>D No 1000Genomes
ENSVATH01684480 103 P>L No 1000Genomes
ENSVATH05311089 115 S>A No 1000Genomes
tmp_2_2916975_T_G 119 S>A No 1000Genomes
ENSVATH14103694 124 D>N No 1000Genomes
ENSVATH05311090 125 L>V No 1000Genomes
ENSVATH05311093 142 H>N No 1000Genomes
ENSVATH05311094 144 E>G No 1000Genomes
tmp_2_2917068_G_T 150 G>C No 1000Genomes
ENSVATH01684481 154 T>M No 1000Genomes
tmp_2_2917089_G_A 157 V>I No 1000Genomes
tmp_2_2917104_C_G 162 L>V No 1000Genomes
ENSVATH11888974 163 I>L No 1000Genomes
ENSVATH14103766 167 L>F No 1000Genomes
tmp_2_2917126_G_A 169 G>E No 1000Genomes
tmp_2_2917125_G_A 169 G>R No 1000Genomes
ENSVATH01684482 171 R>Q No 1000Genomes
ENSVATH05311097 173 T>I No 1000Genomes
ENSVATH01684483 175 Q>L No 1000Genomes
ENSVATH11889155 177 P>L No 1000Genomes
ENSVATH00214410 180 R>K No 1000Genomes
ENSVATH00214410 180 R>T No 1000Genomes
tmp_2_2917166_T_G 182 H>Q No 1000Genomes
ENSVATH05311098 183 P>L No 1000Genomes
ENSVATH05311100 184 N>K No 1000Genomes
tmp_2_2917170_A_T 184 N>Y No 1000Genomes
ENSVATH01684484 193 L>F No 1000Genomes
ENSVATH01684485 194 A>T No 1000Genomes
tmp_2_2917218_A_T 200 S>C No 1000Genomes
ENSVATH05311102 200 S>T No 1000Genomes
tmp_2_2917221_T_G 201 F>V No 1000Genomes
tmp_2_2917225_G_A 202 S>N No 1000Genomes
ENSVATH05311104 205 D>N No 1000Genomes
ENSVATH05311105 206 P>A No 1000Genomes
ENSVATH00214411 207 K>Q No 1000Genomes
tmp_2_2917349_A_C 213 K>N No 1000Genomes
ENSVATH05311112 221 D>Y No 1000Genomes
ENSVATH05311114 229 N>K No 1000Genomes
ENSVATH05311113 229 N>T No 1000Genomes
ENSVATH01684493 230 H>L No 1000Genomes
ENSVATH01684494 232 S>P No 1000Genomes
tmp_2_2917411_C_T 234 P>L No 1000Genomes
ENSVATH01684495 234 P>S No 1000Genomes
ENSVATH01684496 235 K>R No 1000Genomes
tmp_2_2917423_C_T 238 T>I No 1000Genomes
tmp_2_2917432_C_A 241 T>K No 1000Genomes
ENSVATH05311116 245 F>L No 1000Genomes
ENSVATH11889159 249 V>L No 1000Genomes
ENSVATH05311117 252 A>V No 1000Genomes
tmp_2_2917479_G_A 257 A>T No 1000Genomes
ENSVATH05311119 265 V>L No 1000Genomes
ENSVATH01684498 266 V>I No 1000Genomes
ENSVATH05311120 271 R>Q No 1000Genomes
ENSVATH00214415 279 L>I No 1000Genomes
tmp_2_2917555_C_T 282 A>V No 1000Genomes
ENSVATH01684499 283 E>K No 1000Genomes
tmp_2_2917561_C_T 284 P>L No 1000Genomes
ENSVATH05311121 294 G>R No 1000Genomes
ENSVATH14103769 297 E>K No 1000Genomes
ENSVATH01684500 300 R>K No 1000Genomes
ENSVATH05311122 305 Y>* No 1000Genomes
ENSVATH05311123 306 H>Y No 1000Genomes
tmp_2_2917638_C_T 310 R>C No 1000Genomes
tmp_2_2917660_A_G 317 H>R No 1000Genomes
ENSVATH14103770 321 L>F No 1000Genomes
tmp_2_2917699_A_C 330 K>T No 1000Genomes
tmp_2_2917718_A_C 336 L>F No 1000Genomes
ENSVATH01684502 346 S>I No 1000Genomes
tmp_2_2917754_T_G 348 C>W No 1000Genomes
tmp_2_2917753_G_A 348 C>Y No 1000Genomes
ENSVATH11889445 351 A>V No 1000Genomes
tmp_2_2917774_C_T 355 T>I No 1000Genomes
ENSVATH05311126 358 S>P No 1000Genomes
ENSVATH05311127 359 N>K No 1000Genomes
ENSVATH11889447 360 G>E No 1000Genomes
tmp_2_2917792_C_T 361 S>L No 1000Genomes
ENSVATH00214419 361 S>P No 1000Genomes
ENSVATH00214419 361 S>T No 1000Genomes
ENSVATH05311128 364 V>A No 1000Genomes
ENSVATH11889448 367 R>W No 1000Genomes
ENSVATH01684504 370 H>N No 1000Genomes
ENSVATH05311129 373 S>C No 1000Genomes
tmp_2_2917861_A_G 384 K>R No 1000Genomes
ENSVATH05311132 398 V>G No 1000Genomes
ENSVATH01684507 405 E>D No 1000Genomes
tmp_2_2917936_T_C 409 F>S No 1000Genomes
ENSVATH01684508 415 A>G No 1000Genomes
ENSVATH11889450 416 N>S No 1000Genomes
ENSVATH05311134 421 A>T No 1000Genomes
ENSVATH05311135 424 H>R No 1000Genomes
ENSVATH05311140 426 H>N No 1000Genomes
tmp_2_2918107_C_G 431 Q>E No 1000Genomes
tmp_2_2918141_T_C 442 I>T No 1000Genomes
ENSVATH05311142 447 G>V No 1000Genomes
ENSVATH05311144 458 P>L No 1000Genomes
tmp_2_2918194_C_G 460 L>V No 1000Genomes
ENSVATH14103771 472 V>A No 1000Genomes
ENSVATH05311145 475 S>T No 1000Genomes
ENSVATH05311147 480 P>S No 1000Genomes
ENSVATH00214423 483 M>K No 1000Genomes
ENSVATH05311148 487 L>F No 1000Genomes
tmp_2_2918278_A_T 488 I>F No 1000Genomes
tmp_2_2918286_G_T 490 M>I No 1000Genomes
tmp_2_2918291_A_G 492 N>S No 1000Genomes
ENSVATH00214424 499 L>I No 1000Genomes
ENSVATH11889771 500 M>I No 1000Genomes
ENSVATH11889772 502 A>D No 1000Genomes
ENSVATH05311149 510 K>I No 1000Genomes
ENSVATH01684525 512 S>N No 1000Genomes
ENSVATH05311151 532 T>M No 1000Genomes
ENSVATH05311152 533 G>R No 1000Genomes
ENSVATH05311153 534 K>N No 1000Genomes
ENSVATH00214425 536 L>H No 1000Genomes
ENSVATH00214425 536 L>P No 1000Genomes
tmp_2_2918429_G_T 538 S>I No 1000Genomes
ENSVATH01684527 540 S>A No 1000Genomes
ENSVATH01684527 540 S>P No 1000Genomes
ENSVATH05311154 545 E>Q No 1000Genomes
ENSVATH11889773 546 S>R No 1000Genomes
ENSVATH11889774 554 V>L No 1000Genomes
ENSVATH01684531 564 Q>E No 1000Genomes
ENSVATH11889975 568 D>A No 1000Genomes
ENSVATH11889976 570 E>K No 1000Genomes
tmp_2_2918529_G_C 571 M>I No 1000Genomes
ENSVATH11889977 571 M>K No 1000Genomes
ENSVATH14103774 579 A>G No 1000Genomes
ENSVATH14103773 579 A>S No 1000Genomes
ENSVATH01684535 583 N>K No 1000Genomes
ENSVATH11889979 584 L>F No 1000Genomes
ENSVATH01684536 586 R>K No 1000Genomes
ENSVATH01684537 595 D>G No 1000Genomes
ENSVATH01684538 597 E>D No 1000Genomes
tmp_2_2918619_T_G 601 D>E No 1000Genomes
ENSVATH01684540 601 D>N No 1000Genomes
ENSVATH05311156 602 I>M No 1000Genomes
tmp_2_2918630_C_T 605 A>V No 1000Genomes
tmp_2_2918702_G_A 629 S>N No 1000Genomes
ENSVATH11889980 630 E>D No 1000Genomes
tmp_2_2918710_G_C 632 D>H No 1000Genomes
tmp_2_2918746_A_G 644 I>V No 1000Genomes
tmp_2_2918754_G_C 646 L>F No 1000Genomes

No associated diseases with Q84JQ4

2 regional properties for Q84JQ4

Type Name Position InterPro Accession
domain Protein kinase domain 338 - 613 IPR000719
domain Leucine-rich repeat-containing N-terminal, plant-type 24 - 61 IPR013210

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cell membrane ; Single-pass membrane protein
  • ROPGEF12 colocalizes with PRK2 at the apical plasma membrane of pollen tube
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
pollen tube A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

4 GO annotations of biological process

Name Definition
pollen germination The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
pollen tube growth Growth of pollen via tip extension of the intine wall.
protein phosphorylation The process of introducing a phosphate group on to a protein.
regulation of pollen tube growth Any process that modulates the frequency, rate or extent of pollen tube growth.

24 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3E991 PRK6 Pollen receptor-like kinase 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q3E8W4 ANX2 Receptor-like protein kinase ANXUR2 Arabidopsis thaliana (Mouse-ear cress) PR
P43298 TMK1 Receptor protein kinase TMK1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2S4 LECRKS4 L-type lectin-domain containing receptor kinase S.4 Arabidopsis thaliana (Mouse-ear cress) PR
P93050 BSH Probable LRR receptor-like serine/threonine-protein kinase RKF3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN94 At5g59670 Receptor-like protein kinase At5g59670 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SXB4 At1g11300 G-type lectin S-receptor-like serine/threonine-protein kinase At1g11300 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZS4 NIK3 Protein NSP-INTERACTING KINASE 3 Arabidopsis thaliana (Mouse-ear cress) PR
C0LGI2 At1g67720 Probable LRR receptor-like serine/threonine-protein kinase At1g67720 Arabidopsis thaliana (Mouse-ear cress) PR
C0LGG3 At1g51820 Probable LRR receptor-like serine/threonine-protein kinase At1g51820 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AG2 SERK1 Somatic embryogenesis receptor kinase 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN93 At5g59680 Probable LRR receptor-like serine/threonine-protein kinase At5g59680 Arabidopsis thaliana (Mouse-ear cress) PR
Q8LPS5 SERK5 Somatic embryogenesis receptor kinase 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SNA3 At3g46340 Putative receptor-like protein kinase At3g46340 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LPZ9 SD113 G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13 Arabidopsis thaliana (Mouse-ear cress) SS
Q9ZQR3 At2g14510 Leucine-rich repeat receptor-like serine/threonine-protein kinase At2g14510 Arabidopsis thaliana (Mouse-ear cress) PR
O64477 At2g19130 G-type lectin S-receptor-like serine/threonine-protein kinase At2g19130 Arabidopsis thaliana (Mouse-ear cress) SS
Q9LIG2 At3g21340 Receptor-like protein kinase At3g21340 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RWW0 ALE2 Receptor-like serine/threonine-protein kinase ALE2 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RWZ5 SD25 G-type lectin S-receptor-like serine/threonine-protein kinase SD2-5 Arabidopsis thaliana (Mouse-ear cress) PR
C0LGW2 PAM74 Probable LRR receptor-like serine/threonine-protein kinase PAM74 Arabidopsis thaliana (Mouse-ear cress) PR
Q9XIC7 SERK2 Somatic embryogenesis receptor kinase 2 Arabidopsis thaliana (Mouse-ear cress) PR
P43293 PBL11 Probable serine/threonine-protein kinase PBL11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRP3 At3g17420 Probable receptor-like protein kinase At3g17420 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MESKCLMFVS IVSVFFMVVN GVSETETLLK FKNSLVIGRA NALESWNRRN PPCKWTGVLC
70 80 90 100 110 120
DRGFVWGLRL ENLELSGSID IEALMGLNSL RSLSFINNKF KGPFPEFKKL VALKSLYLSN
130 140 150 160 170 180
NQFDLEIPKD AFDGMGWLKK LHLEQNNFIG EIPTSLVKSP KLIELRLDGN RFTGQIPEFR
190 200 210 220 230 240
HHPNMLNLSN NALAGQIPNS FSTMDPKLFE GNKGLCGKPL DTKCSSPYNH SSEPKSSTKK
250 260 270 280 290 300
TSSKFLYIVA AAVAALAASL IIIGVVIFLI RRRKKKQPLL SAEPGPSSLQ MRAGIQESER
310 320 330 340 350 360
GQGSYHSQNR AAKKMIHTTK LSFLRDDKGK FELQDLLKAS AEILGSGCFG ASYKTLLSNG
370 380 390 400 410 420
SVMVVKRFKH MNSAGIDEFQ EHMKRLGRLN HENLLPIVAY YYKKEEKLFV SDFVANGSLA
430 440 450 460 470 480
AHLHGHKSLG QPSLDWPTRF NIVKGVGRGL LYLHKNLPSL MAPHGHLKSS NVLLSEKFEP
490 500 510 520 530 540
LLMDYGLIPM INEESAQELM VAYKSPEYVK QSRVTKKTDV WGLGVLILEI LTGKLLESFS
550 560 570 580 590 600
QVDKESEEDL ASWVRSSFKG EWTQELFDQE MGKTSNCEAH ILNLMRIGLS CCEVDVEKRL
610 620 630 640
DIREAVEKME DLMKEREQGD DDFYSTYASE ADGRSSRGLS SEGINLS