Q80X60

PR
Gene name
Efcab3
Protein name
EF-hand calcium-binding domain-containing protein 3
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:70894
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

148-230 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q80X60

Entry ID Method Resolution Chain Position Source
AF-Q80X60-F1 Predicted AlphaFoldDB

17 variants for Q80X60

Variant ID(s) Position Change Description Diseaes Association Provenance
rs223223299 27 L>F No EVA
rs256018218 27 L>S No EVA
rs3389209751 108 N>D No EVA
rs3389179330 166 R>G No EVA
rs3389220278 171 H>Y No EVA
rs227203999 175 M>L No EVA
rs27005391 177 S>N No EVA
rs3389224477 252 F>C No EVA
rs3389224457 256 Q>H No EVA
rs3389183602 283 Q>H No EVA
rs227713257 291 K>R No EVA
rs3389179246 310 K>R No EVA
rs3389196661 374 W>* No EVA
rs3389210157 381 E>D No EVA
rs3402069940 395 M>I No EVA
rs3402719800 395 M>L No EVA
rs3389207728 415 D>E No EVA

No associated diseases with Q80X60

2 regional properties for Q80X60

Type Name Position InterPro Accession
domain EF-hand domain 62 - 116 IPR002048
binding_site EF-Hand 1, calcium-binding site 94 - 106 IPR018247

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6P1E8 Efcab6 EF-hand calcium-binding domain-containing protein 6 Mus musculus (Mouse) PR
Q66HC0 Efcab3 EF-hand calcium-binding domain-containing protein 3 Rattus norvegicus (Rat) PR
Q0JC44 CML22 Probable calcium-binding protein CML22 Oryza sativa subsp japonica (Rice) PR
Q9FYK2 CML25 Probable calcium-binding protein CML25 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRN6 CML22 Probable calcium-binding protein CML22 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAVSEIKATM KLKPLKAPVF HKRDKDLRGS FSDHLKHKES KLSPAQLEAF RNAYNFFTKD
70 80 90 100 110 120
RTGCIDSHGL ISTIAKLGMN LNTYDIYNEL KCADLDRDGK INFSDFINVL TDKKLFLKAV
130 140 150 160 170 180
VPEKKICLDL ANNPGILLFE ILSKFVETSS LHRKDIIELV SYFRKRFQES HSEIMWSSYG
190 200 210 220 230 240
RRGLKSEICS PPRSSTAAFA NSARISIMKE RDLYKFLEAL KRCNLRTDSP YSKIPVFPLF
250 260 270 280 290 300
PDVDGTVMGK PFKDTQKIEM LRRKEPLTFF EDYFFNKRDW KTQAMNVKPL KSASGYSDDI
310 320 330 340 350 360
LAIDHLFKKK QHWTVTDAAA IKQHVKKATE SYNLGIALDH RKEMLNLWKK IRGDLVGIES
370 380 390 400 410 420
NNESFYNTFS TYTWSWNVCQ ELLSAKDLRL HDASMNKSSP SNSGLSSPSD FSESDPETGR
430
KRKRKSSRGF RQ