Q7Z7E8
PR
Gene name |
UBE2Q1 (NICE5, UBE2Q, PRO3094) |
Protein name |
Ubiquitin-conjugating enzyme E2 Q1 |
Names |
E2 ubiquitin-conjugating enzyme Q1, Protein NICE-5, Ubiquitin carrier protein Q1, Ubiquitin-protein ligase Q1 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:55585 |
EC number |
2.3.2.23: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q7Z7E8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2QGX | X-ray | 256 A | A/B/C/D | 247-414 | PDB |
| AF-Q7Z7E8-F1 | Predicted | AlphaFoldDB |
176 variants for Q7Z7E8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs971266222 CA30822557 |
6 | P>Q | No |
ClinGen TOPMed |
|
|
rs771152409 CA1130573 |
11 | Q>L | No |
ClinGen ExAC |
|
|
CA342628945 rs1184846428 |
12 | P>A | No |
ClinGen TOPMed |
|
|
CA342628941 rs1453369815 |
12 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1453369815 CA342628942 |
12 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1402375108 CA342628929 |
14 | P>L | No |
ClinGen TOPMed |
|
|
CA342628931 rs1402375108 |
14 | P>Q | No |
ClinGen TOPMed |
|
|
rs1318819764 CA342628925 |
15 | G>A | No |
ClinGen TOPMed |
|
|
CA342628913 rs1371343835 |
16 | Q>H | No |
ClinGen TOPMed |
|
|
CA342628915 rs1294741983 |
16 | Q>L | No |
ClinGen TOPMed |
|
|
rs1439647371 CA342628889 |
18 | L>R | No |
ClinGen TOPMed |
|
|
rs1225993830 CA342628881 |
19 | G>E | No |
ClinGen TOPMed |
|
|
rs1251189872 CA342628883 |
19 | G>W | No |
ClinGen TOPMed gnomAD |
|
|
CA342628859 rs1285649866 |
21 | Q>R | No |
ClinGen TOPMed |
|
|
rs917971089 CA30822550 |
22 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1213787886 CA342628821 |
24 | A>V | No |
ClinGen TOPMed |
|
|
rs1254911006 CA342628810 |
25 | P>R | No |
ClinGen TOPMed |
|
|
CA342628795 rs1326049244 |
26 | G>E | No |
ClinGen TOPMed gnomAD |
|
|
rs992248839 CA30822547 |
26 | G>R | No |
ClinGen TOPMed |
|
|
CA30822539 rs959485135 |
27 | A>S | No |
ClinGen TOPMed |
|
| TCGA novel | 27 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342628785 rs1407571668 |
27 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA342628782 rs1221282076 |
28 | G>R | No |
ClinGen gnomAD |
|
|
CA342628752 rs1398856343 |
30 | G>D | No |
ClinGen TOPMed |
|
|
rs549444803 CA30822469 |
32 | G>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA1130569 rs549444803 |
32 | G>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA30822484 rs778022056 CA1130570 |
32 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs549444803 CA1130568 |
32 | G>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1448704725 CA342628378 |
33 | G>A | No |
ClinGen gnomAD |
|
|
CA1130567 CA30822459 rs755410020 |
33 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755410020 CA1130566 |
33 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs759160193 | 34 | G>A | Variant assessed as Somatic; 0.0007761 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342628374 rs752073705 |
34 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342628373 rs752073705 |
34 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1130565 rs752073705 |
34 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1469467683 CA342628365 |
34 | G>V | No |
ClinGen gnomAD |
|
|
CA342628361 rs1189896763 |
35 | P>A | No |
ClinGen TOPMed |
|
|
CA1130562 rs765835407 |
35 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342628342 rs1161574903 |
36 | G>A | No |
ClinGen gnomAD |
|
|
rs1356816076 CA342628330 |
37 | P>L | No |
ClinGen gnomAD |
|
|
CA342628335 rs1241942353 |
37 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA342628328 rs1571012636 |
38 | G>R | No |
ClinGen Ensembl |
|
|
CA342628303 rs1295712310 |
40 | C>S | No |
ClinGen TOPMed |
|
|
rs1463087988 CA342628281 |
42 | R>K | No |
ClinGen gnomAD |
|
|
CA342628274 rs1241671911 |
42 | R>S | No |
ClinGen gnomAD |
|
| TCGA novel | 43 | R>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 43 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342628217 rs1260887468 |
48 | L>V | No |
ClinGen gnomAD |
|
|
CA342628069 rs775595854 |
67 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342628049 rs1185228904 |
70 | S>I | No |
ClinGen TOPMed |
|
| TCGA novel | 74 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs772172320 CA1130553 |
76 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA1130552 rs369150212 |
78 | A>D | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 79 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1475538185 CA342627987 |
80 | G>V | No |
ClinGen TOPMed |
|
|
rs1446972119 CA342627984 |
81 | A>T | No |
ClinGen gnomAD |
|
|
rs773220291 CA342627975 |
82 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA30822358 rs376201812 |
82 | G>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs773220291 CA1130551 |
82 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342627973 rs1264335540 |
83 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA342627969 rs1414651090 |
83 | A>V | No |
ClinGen TOPMed |
|
|
rs1484714830 CA342627960 |
85 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
rs202059318 CA1130549 |
86 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA342627956 rs202059318 |
86 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA342627949 rs1360996342 |
87 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA342627943 rs1340300733 |
88 | G>R | No |
ClinGen TOPMed |
|
|
rs747413918 CA1130546 |
89 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1130547 rs375766283 |
89 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 90 | H>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1485319244 CA342627925 |
91 | L>F | No |
ClinGen TOPMed |
|
|
CA342627923 rs1297518207 |
91 | L>P | No |
ClinGen gnomAD |
|
| TCGA novel | 91 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA30822319 rs917087614 |
92 | P>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 93 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs372729486 CA1130542 |
93 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1130540 rs372729486 |
93 | P>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1130541 rs372729486 |
93 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs749948005 CA342627915 |
93 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749948005 CA1130543 |
93 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342627913 rs1434648674 |
94 | R>L | No |
ClinGen TOPMed |
|
|
CA1130538 rs760511660 |
94 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs200884226 CA1130537 |
95 | G>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200884226 CA1130536 |
95 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA342627901 rs1191555387 |
96 | S>L | No |
ClinGen gnomAD |
|
|
rs773274880 CA1130534 |
98 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA1130533 rs769776532 |
99 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs979819603 CA30822224 |
105 | H>Y | No |
ClinGen TOPMed |
|
|
rs1443321482 COSM332343 CA342627832 |
107 | N>S | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs1179106875 CA342627233 |
110 | E>Q | No |
ClinGen gnomAD |
|
| TCGA novel | 113 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 114 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1426692240 CA342627066 |
115 | V>A | No |
ClinGen gnomAD |
|
|
CA1130503 rs777494406 |
116 | P>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 135 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342626396 rs1295887242 |
135 | L>P | No |
ClinGen TOPMed |
|
|
rs201163919 CA1130500 |
136 | V>G | No |
ClinGen ExAC gnomAD |
|
|
rs1262680395 CA342626358 |
137 | D>E | No |
ClinGen gnomAD |
|
|
CA1130498 rs751419079 |
137 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA342626362 rs751419079 |
137 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA1130497 rs766212921 |
138 | I>K | No |
ClinGen ExAC |
|
|
rs1352036938 CA342626338 |
138 | I>M | No |
ClinGen gnomAD |
|
|
rs1002897010 CA30820465 |
138 | I>V | No |
ClinGen TOPMed |
|
| TCGA novel | 139 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs753847447 CA1130495 |
140 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA1130494 rs764169973 |
144 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA30820067 rs200287421 |
153 | I>V | No |
ClinGen Ensembl |
|
|
CA1130467 rs766865464 |
168 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA342625494 rs1199621876 |
169 | E>K | No |
ClinGen gnomAD |
|
|
rs1231969743 CA342625409 |
172 | D>E | No |
ClinGen TOPMed |
|
|
rs1274144160 CA342625389 |
173 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
CA342625343 rs1553202293 |
176 | P>T | No |
ClinGen Ensembl |
|
|
CA342625325 rs1489252477 |
177 | A>T | No |
ClinGen gnomAD |
|
|
CA342625285 rs1216621205 |
179 | Q>E | No |
ClinGen gnomAD |
|
|
rs560359173 CA1130439 |
180 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA342625147 rs1571009740 |
181 | T>R | No |
ClinGen Ensembl |
|
|
CA342625135 rs1226768476 |
182 | Q>E | No |
ClinGen TOPMed |
|
|
CA1130437 rs372396696 CA1130436 |
184 | D>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC TOPMed gnomAD NCI-TCGA |
|
rs770709805 CA1130438 |
184 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA1130434 rs751729278 |
185 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766654924 CA30819517 |
193 | E>G | No |
ClinGen Ensembl |
|
|
CA342624504 rs1277200902 |
198 | T>R | No |
ClinGen TOPMed |
|
| TCGA novel | 199 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1217221602 CA342624450 |
200 | D>E | No |
ClinGen TOPMed |
|
|
CA30818098 rs1042067027 |
200 | D>G | No |
ClinGen TOPMed |
|
|
CA342624472 rs1290868665 |
200 | D>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 208 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1130412 rs142718155 |
209 | E>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 210 | E>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs528168401 CA1130408 |
212 | A>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA1130409 rs528168401 |
212 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA342624019 rs764645047 |
214 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA1130407 rs764645047 |
214 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA342623934 rs1361589333 |
218 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA342623605 rs1378027309 |
228 | A>V | No |
ClinGen TOPMed |
|
|
rs1170803831 CA342623219 |
235 | K>R | No |
ClinGen TOPMed |
|
|
rs373938647 CA1130401 |
243 | N>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1130400 rs762787582 |
243 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs771114797 CA1130371 |
245 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1313474576 CA342622667 |
245 | A>V | No |
ClinGen TOPMed |
|
|
rs770403490 CA30817562 |
246 | V>M | No |
ClinGen Ensembl |
|
| TCGA novel | 252 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA30817537 rs894189614 |
262 | D>V | No |
ClinGen Ensembl |
|
|
CA342621981 rs1318409304 |
263 | I>T | No |
ClinGen TOPMed |
|
|
rs1274387760 CA342622000 |
263 | I>V | No |
ClinGen gnomAD |
|
|
rs781649844 CA1130366 |
265 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA1130365 rs755537885 |
271 | G>D | No |
ClinGen ExAC gnomAD |
|
|
COSM206573 rs1360882504 CA342621442 |
277 | E>K | lung Variant assessed as Somatic; 0.0 impact. large_intestine endometrium breast [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs763990597 CA1130337 |
279 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs1356115562 CA342621382 |
280 | N>S | No |
ClinGen gnomAD |
|
|
CA1130318 rs755837391 |
301 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA30816850 rs372294769 |
301 | N>S | No |
ClinGen gnomAD |
|
| TCGA novel | 302 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342620018 rs1244213945 |
304 | Q>H | No |
ClinGen gnomAD |
|
|
rs200026897 CA1130315 |
307 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342619796 rs1239330949 |
312 | A>G | No |
ClinGen TOPMed |
|
|
rs1197670799 CA342619771 |
313 | D>A | No |
ClinGen gnomAD |
|
|
rs1255718672 COSM3418105 CA342619788 |
313 | D>N | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1415885886 CA342619714 |
315 | I>V | No |
ClinGen TOPMed |
|
|
CA342619658 rs1217405716 |
317 | L>F | No |
ClinGen gnomAD |
|
|
rs760934058 CA1130309 |
322 | K>I | No |
ClinGen ExAC gnomAD |
|
|
CA342619506 rs760934058 |
322 | K>T | No |
ClinGen ExAC gnomAD |
|
|
rs780802766 CA1130276 |
334 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA1130275 rs768464949 |
336 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA342618937 rs1482624334 |
340 | S>C | No |
ClinGen gnomAD |
|
|
rs1263328847 CA342618899 |
341 | G>E | No |
ClinGen gnomAD |
|
|
CA1130256 rs779824604 |
358 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA342617599 rs1202188337 |
370 | I>V | No |
ClinGen gnomAD |
|
|
CA342616462 rs1279374126 |
395 | L>V | No |
ClinGen Ensembl |
|
| TCGA novel | 396 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1414307245 CA342616296 |
399 | Q>E | No |
ClinGen gnomAD |
|
|
rs779158559 CA1130207 |
404 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA1130205 rs754369992 |
410 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| rs1415370636 | 412 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 413 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771165587 CA1130184 |
415 | Y>D | No |
ClinGen ExAC gnomAD |
|
|
CA1130183 rs749699818 |
417 | P>L | No |
ClinGen ExAC gnomAD |
No associated diseases with Q7Z7E8
No regional properties for Q7Z7E8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q7Z7E8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.23 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| filopodium | Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ubiquitin conjugating enzyme activity | Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| embryo implantation | Attachment of the blastocyst to the uterine lining. |
| fertilization | The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). |
| mating behavior | The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. |
| prolactin secretion | The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. |
| protein polyubiquitination | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. |
| reproductive system development | The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. |
| suckling behavior | Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q32L27 | UBE2Q2 | Ubiquitin-conjugating enzyme E2 Q2 | Bos taurus (Bovine) | PR |
| Q9H8T0 | AKTIP | AKT-interacting protein | Homo sapiens (Human) | PR |
| Q9Y385 | UBE2J1 | Ubiquitin-conjugating enzyme E2 J1 | Homo sapiens (Human) | PR |
| P61086 | UBE2K | Ubiquitin-conjugating enzyme E2 K | Homo sapiens (Human) | PR |
| Q9NPD8 | UBE2T | Ubiquitin-conjugating enzyme E2 T | Homo sapiens (Human) | PR |
| O00762 | UBE2C | Ubiquitin-conjugating enzyme E2 C | Homo sapiens (Human) | PR |
| O14933 | UBE2L6 | Ubiquitin/ISG15-conjugating enzyme E2 L6 | Homo sapiens (Human) | PR |
| Q96LR5 | UBE2E2 | Ubiquitin-conjugating enzyme E2 E2 | Homo sapiens (Human) | PR |
| Q969T4 | UBE2E3 | Ubiquitin-conjugating enzyme E2 E3 | Homo sapiens (Human) | PR |
| A1L167 | UBE2QL1 | Ubiquitin-conjugating enzyme E2Q-like protein 1 | Homo sapiens (Human) | PR |
| Q16763 | UBE2S | Ubiquitin-conjugating enzyme E2 S | Homo sapiens (Human) | EV |
| A0PJN4 | Ube2ql1 | Ubiquitin-conjugating enzyme E2Q-like protein 1 | Mus musculus (Mouse) | PR |
| Q7TSS2 | Ube2q1 | Ubiquitin-conjugating enzyme E2 Q1 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQQPQPQGQQ | QPGPGQQLGG | QGAAPGAGGG | PGGGPGPGPC | LRRELKLLES | IFHRGHERFR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IASACLDELS | CEFLLAGAGG | AGAGAAPGPH | LPPRGSVPGD | PVRIHCNITE | SYPAVPPIWS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VESDDPNLAA | VLERLVDIKK | GNTLLLQHLK | RIISDLCKLY | NLPQHPDVEM | LDQPLPAEQC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TQEDVSSEDE | DEEMPEDTED | LDHYEMKEEE | PAEGKKSEDD | GIGKENLAIL | EKIKKNQRQD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YLNGAVSGSV | QATDRLMKEL | RDIYRSQSFK | GGNYAVELVN | DSLYDWNVKL | LKVDQDSALH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NDLQILKEKE | GADFILLNFS | FKDNFPFDPP | FVRVVSPVLS | GGYVLGGGAI | CMELLTKQGW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SSAYSIESVI | MQISATLVKG | KARVQFGANK | SQYSLTRAQQ | SYKSLVQIHE | KNGWYTPPKE |
| DG |