Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7Y183

Entry ID Method Resolution Chain Position Source
AF-Q7Y183-F1 Predicted AlphaFoldDB

No variants for Q7Y183

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7Y183

No associated diseases with Q7Y183

5 regional properties for Q7Y183

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 651 - 892 IPR003439
domain AAA+ ATPase domain 678 - 869 IPR003593
domain ABC transporter type 1, transmembrane domain 315 - 621 IPR011527-1
domain ABC transporter type 1, transmembrane domain 962 - 1218 IPR011527-2
conserved_site ABC transporter-like, conserved site 792 - 806 IPR017871

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
  • Nucleus, nucleolus
  • Localization is not affected by temperature
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

16 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P53166 MRH4 ATP-dependent RNA helicase MRH4, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P15424 MSS116 ATP-dependent RNA helicase MSS116, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q29S22 DDX47 Probable ATP-dependent RNA helicase DDX47 Bos taurus (Bovine) PR
Q9NUL7 DDX28 Probable ATP-dependent RNA helicase DDX28 Homo sapiens (Human) PR
Q9H0S4 DDX47 Probable ATP-dependent RNA helicase DDX47 Homo sapiens (Human) PR
Q9CWT6 Ddx28 Probable ATP-dependent RNA helicase DDX28 Mus musculus (Mouse) PR
Q9CWX9 Ddx47 Probable ATP-dependent RNA helicase DDX47 Mus musculus (Mouse) PR
Q6Z2Z4 Os02g0146600 Eukaryotic initiation factor 4A-3 Oryza sativa subsp japonica (Rice) PR
P35683 Os06g0701100 Eukaryotic initiation factor 4A-1 Oryza sativa subsp japonica (Rice) PR
Q5K5B6 Os07g0647900 DEAD-box ATP-dependent RNA helicase 57 Oryza sativa subsp japonica (Rice) PR
Q0DBS1 Os06g0535100 Putative DEAD-box ATP-dependent RNA helicase 51 Oryza sativa subsp japonica (Rice) PR
Q0D622 Os07g0517000 DEAD-box ATP-dependent RNA helicase 32 Oryza sativa subsp japonica (Rice) PR
Q8L4E9 Os07g0633500 DEAD-box ATP-dependent RNA helicase 36 Oryza sativa subsp japonica (Rice) PR
P34580 T26G10.1 Putative ATP-dependent RNA helicase T26G10.1 Caenorhabditis elegans PR
P34668 ZK686.2 Putative ATP-dependent RNA helicase ZK686.2 Caenorhabditis elegans PR
Q8GY84 RH10 DEAD-box ATP-dependent RNA helicase 10 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAKKKDVEVE ELDEEVVAAA AAPAADGGEE QEAEPPARRP STFAELGVVP ELVAACDAMG
70 80 90 100 110 120
WKEPTRIQAE AIPHALEGRD LIGLGQTGSG KTGAFALPII QALLKQDKPQ ALFACVLSPT
130 140 150 160 170 180
RELAFQIGQQ FEALGSAIGL SCTVLVGGVD RVQQAVSLAK RPHIVVGTPG RLLDHLTDTK
190 200 210 220 230 240
GFSLNKLKYL VLDEADKLLN VEFQKALDDI LNVIPKERRT FLFSATMTNK VSKLQRACLR
250 260 270 280 290 300
NPVKVEVASK YSTVDTLRQE FYFVPADYKD CFLVHVLNEL PGSMIMIFVR TCESTRLLAL
310 320 330 340 350 360
TLRNLRFKAI SISGQMSQDK RLGALNRFKT KDCNILICTD VASRGLDIQG VDVVINYDIP
370 380 390 400 410 420
MNSKDYVHRV GRTARAGNTG YAVSLVNQYE AMWFKMIEKL LGYEIPDRKV DNAEIMILRE
430 440 450 460 470
RISDSKRIAL TTMKEGGGHK KKRRKNEDDE EEEERNAPVS RKSKSFNKSR RR