Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7XTE8

Entry ID Method Resolution Chain Position Source
AF-Q7XTE8-F1 Predicted AlphaFoldDB

No variants for Q7XTE8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7XTE8

No associated diseases with Q7XTE8

13 regional properties for Q7XTE8

Type Name Position InterPro Accession
domain B-box-type zinc finger 94 - 135 IPR000315
domain Zinc finger, RING-type 16 - 61 IPR001841
domain B30.2/SPRY domain 292 - 481 IPR001870
domain SPRY domain 362 - 478 IPR003877
domain Butyrophylin-like, SPRY domain 308 - 325 IPR003879-1
domain Butyrophylin-like, SPRY domain 325 - 342 IPR003879-2
domain Butyrophylin-like, SPRY domain 347 - 371 IPR003879-3
domain Butyrophylin-like, SPRY domain 379 - 392 IPR003879-4
domain Butyrophylin-like, SPRY domain 422 - 446 IPR003879-5
domain Butyrophylin-like, SPRY domain 452 - 470 IPR003879-6
domain SPRY-associated 309 - 361 IPR006574
conserved_site Zinc finger, RING-type, conserved site 31 - 40 IPR017907
domain TRIM10, RING-HC finger 9 - 69 IPR042784

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein localization Any process in which a protein is transported to, or maintained in, a specific location.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

38 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q04917 YWHAH 14-3-3 protein eta Homo sapiens (Human) PR
P61981 YWHAG 14-3-3 protein gamma Homo sapiens (Human) PR
P31946 YWHAB 14-3-3 protein beta/alpha Homo sapiens (Human) PR
P27348 YWHAQ 14-3-3 protein theta Homo sapiens (Human) PR
P63104 YWHAZ 14-3-3 protein zeta/delta Homo sapiens (Human) PR
P49106 GRF1 14-3-3-like protein GF14-6 Zea mays (Maize) PR
Q01526 GRF2 14-3-3-like protein GF14-12 Zea mays (Maize) PR
P68510 Ywhah 14-3-3 protein eta Mus musculus (Mouse) PR
P63101 Ywhaz 14-3-3 protein zeta/delta Mus musculus (Mouse) PR
P93784 HOX 14-3-3-like protein 16R Solanum tuberosum (Potato) PR
Q41418 14-3-3-like protein Solanum tuberosum (Potato) PR
P63102 Ywhaz 14-3-3 protein zeta/delta Rattus norvegicus (Rat) PR
Q6EUP4 GF14E 14-3-3-like protein GF14-E Oryza sativa subsp japonica (Rice) PR
Q06967 GF14F 14-3-3-like protein GF14-F Oryza sativa subsp japonica (Rice) PR
Q2R2W2 GF14D 14-3-3-like protein GF14-D Oryza sativa subsp japonica (Rice) PR
Q6ZKC0 GF14C 14-3-3-like protein GF14-C Oryza sativa subsp japonica (Rice) PR
Q84J55 GF14A 14-3-3-like protein GF14-A Oryza sativa subsp japonica (Rice) PR
Q2R1D5 GF14H Putative 14-3-3-like protein GF14-H Oryza sativa subsp japonica (Rice) PR
Q96452 GF14C 14-3-3-like protein C Glycine max (Soybean) (Glycine hispida) PR
Q96453 GF14D 14-3-3-like protein D Glycine max (Soybean) (Glycine hispida) PR
Q96450 GF14A 14-3-3-like protein A Glycine max (Soybean) (Glycine hispida) PR
Q9C5W6 GRF12 14-3-3-like protein GF14 iota Arabidopsis thaliana (Mouse-ear cress) PR
Q9S9Z8 GRF11 14-3-3-like protein GF14 omicron Arabidopsis thaliana (Mouse-ear cress) PR
P46077 GRF4 14-3-3-like protein GF14 phi Arabidopsis thaliana (Mouse-ear cress) PR
Q01525 GRF2 14-3-3-like protein GF14 omega Arabidopsis thaliana (Mouse-ear cress) PR
Q96299 GRF9 14-3-3-like protein GF14 mu Arabidopsis thaliana (Mouse-ear cress) PR
P42645 GRF5 14-3-3-like protein GF14 upsilon Arabidopsis thaliana (Mouse-ear cress) PR
Q96300 GRF7 14-3-3-like protein GF14 nu Arabidopsis thaliana (Mouse-ear cress) PR
P42644 GRF3 14-3-3-like protein GF14 psi Arabidopsis thaliana (Mouse-ear cress) PR
P93212 TFT7 14-3-3 protein 7 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93209 TFT3 14-3-3 protein 3 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93207 TFT10 14-3-3 protein 10 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93214 TFT9 14-3-3 protein 9 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93211 TFT6 14-3-3 protein 6 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93206 TFT1 14-3-3 protein 1 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93213 TFT8 14-3-3 protein 8 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93208 TFT2 14-3-3 protein 2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P42652 TFT4 14-3-3 protein 4 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MSAQAELSRE ENVYMAKLAE QAERYEEMVE FMEKVAKTVD SEELTVEERN LLSVAYKNVI
70 80 90 100 110 120
GARRASWRII SSIEQKEESR GNEDRVTLIK DYRGKIETEL TKICDGILKL LESHLVPSST
130 140 150 160 170 180
APESKVFYLK MKGDYYRYLA EFKTGAERKD AAENTMVAYK AAQDIALAEL PPTHPIRLGL
190 200 210 220 230 240
ALNFSVFYYE ILNSPDRACN LAKQAFDEAI SELDTLSEES YKDSTLIMQL LRDNLTLWTS
250 260
DISEDTAEEI REAPKRDSSE GQ