| brain development |
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
| camera-type eye morphogenesis |
The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. |
| closure of optic fissure |
The closure of the temporary ventral gap in the optic cup that contributes to its shaping. |
| cornea development in camera-type eye |
The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. |
| embryonic digestive tract morphogenesis |
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed. |
| embryonic skeletal system morphogenesis |
The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase. |
| eyelid development in camera-type eye |
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. |
| glial cell development |
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. |
| glial cell proliferation |
The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. |
| hard palate development |
The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes. |
| kidney development |
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. |
| lens morphogenesis in camera-type eye |
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. |
| lung morphogenesis |
The process in which the anatomical structures of the lung are generated and organized. |
| negative regulation of gene expression |
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| negative regulation of glial cell proliferation |
Any process that stops or decreases the rate or extent of glial cell proliferation. |
| negative regulation of lymphocyte proliferation |
Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. |
| negative regulation of transcription by RNA polymerase II |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| negative regulation of transcription regulatory region DNA binding |
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding. |
| nervous system development |
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
| neuroepithelial cell differentiation |
The process in which epiblast cells acquire specialized features of neuroepithelial cells. |
| neuron differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a neuron. |
| noradrenergic neuron differentiation |
The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. |
| oligodendrocyte development |
The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. |
| outflow tract morphogenesis |
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. |
| positive regulation of BMP signaling pathway |
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity. |
| positive regulation of DNA-templated transcription |
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| positive regulation of gene expression |
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| positive regulation of hippo signaling |
Any process that activates or increases the frequency, rate or extent of hippo signaling. |
| positive regulation of hormone secretion |
Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. |
| positive regulation of lens epithelial cell proliferation |
Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation. |
| positive regulation of neurogenesis |
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. |
| positive regulation of neuron differentiation |
Any process that activates or increases the frequency, rate or extent of neuron differentiation. |
| positive regulation of ossification |
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. |
| positive regulation of osteoblast differentiation |
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. |
| positive regulation of stem cell proliferation |
Any process that activates or increases the frequency, rate or extent of stem cell proliferation. |
| positive regulation of transcription by RNA polymerase II |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of transforming growth factor beta receptor signaling pathway |
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway. |
| skeletal muscle cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. |
| soft palate development |
The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate. |
| spinal cord development |
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. |
| sympathetic nervous system development |
The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. |
| ventricular septum morphogenesis |
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. |
