Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7K4V4

Entry ID Method Resolution Chain Position Source
AF-Q7K4V4-F1 Predicted AlphaFoldDB

No variants for Q7K4V4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7K4V4

No associated diseases with Q7K4V4

1 regional properties for Q7K4V4

Type Name Position InterPro Accession
domain Ubiquitin-conjugating enzyme E2 20 - 176 IPR000608

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Chromosome
  • Associates with multiple polytene bands and interbands on chromosomes
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
ubiquitin-protein transferase activity Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.

3 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.
sperm individualization The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5ZJJ5 AKTIP AKT-interacting protein Gallus gallus (Chicken) PR
Q9H8T0 AKTIP AKT-interacting protein Homo sapiens (Human) PR
Q64362 Aktip AKT-interacting protein Mus musculus (Mouse) PR
Q5FVH4 Aktip AKT-interacting protein Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MTLDLDAHKK DDKLLITTIQ QEYKILAEYK MIESEKLSGI YVIPSYANSL QWFGVFFGRQ
70 80 90 100 110 120
GLYAESVFRF TILLPDRFPD DKSLPSIIFQ QDVIHPHVCP YTHSLDVSHA FPEWRCGEDH
130 140 150 160 170 180
LWQLLKYLQV IFSDPLDSIR GIEVDKLKNS EAAELLMNNK EEYVARVQEN IKESKEHIFD
190 200 210 220 230 240
TPPTEDPHYI VFEKFQQDVH GPVLERIKAG RSKLTEPSAQ QANGGHATGL SWVKEGEFKP
LSIE