AiPD: Autoinhibited Protein Database

Q6R2W3

Gene name	ZBED9 (Buster4, KIAA1925, SCAND3, ZNF305P2, ZNF452)
Protein name	SCAN domain-containing protein 3
Names	Transposon-derived Buster4 transposase-like protein, Zinc finger BED domain-containing protein 9
Species	Homo sapiens (Human)
KEGG Pathway	hsa:114821
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-70 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q6R2W3

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q6R2W3-F1	Predicted				AlphaFoldDB

865 variants for Q6R2W3

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs770350324 CA3685607	2	E>V		No	ClinGen ExAC gnomAD
CA135894557 rs958315702	4	V>I		No	ClinGen TOPMed
rs1030959535 CA135894529	7	V>I		No	ClinGen TOPMed gnomAD
rs777014935 CA3685605	9	P>L		No	ClinGen ExAC TOPMed gnomAD
rs373132271 CA3685604	10	A>V		No	ClinGen ESP ExAC gnomAD
CA362952490 rs1369920991	11	L>W		No	ClinGen TOPMed
CA3685602 COSM3430420 rs777450959	12	A>V	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs151037202 CA3685601	13	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA362952455 rs1465580721	15	A>T		No	ClinGen gnomAD
CA3685599 rs778226085	18	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1251431620	21	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	21	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1316450734 CA362952369	22	I>T		No	ClinGen gnomAD
CA3685598 rs754969254	29	E>D		No	ClinGen ExAC gnomAD
CA362952292 rs1226681300	29	E>V		No	ClinGen TOPMed
TCGA novel	30	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1562042069 CA362952267	31	D>E		No	ClinGen Ensembl
rs1365611632 CA362952251	33	T>P		No	ClinGen gnomAD
CA3685595 rs766299245	36	Q>*		No	ClinGen ExAC gnomAD
CA362952201 rs1344153286	37	E>K		No	ClinGen gnomAD
CA362952200 rs1344153286	37	E>Q		No	ClinGen gnomAD
rs375224581 CA3685594	37	E>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA362952178 rs1272191869	39	A>T		No	ClinGen TOPMed
rs906782517 CA135894415	40	L>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	40	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685591 rs764369384	41	R>H		No	ClinGen ExAC gnomAD
rs1025112362 CA135894414	42	R>K		No	ClinGen TOPMed
TCGA novel	43	N>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1172572725 CA362952129	45	S>F		No	ClinGen gnomAD
CA362952124 rs1187278442	46	Y>C		No	ClinGen gnomAD
rs752829293 CA3685589	46	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA3685587 rs760061189	47	T>I		No	ClinGen ExAC gnomAD
rs765264362 CA3685588	47	T>P		No	ClinGen ExAC gnomAD
rs200336287 COSM3410874 CA135894330	52	R>H	Variant assessed as Somatic; impact. central_nervous_system [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes NCI-TCGA
rs1279918472 CA362952070	54	R>H		No	ClinGen gnomAD
rs1229374802 CA362952068	55	F>L		No	ClinGen gnomAD
CA3685584 rs771326238	56	R>G		No	ClinGen ExAC gnomAD
CA3685581 rs771771243	59	C>*		No	ClinGen ExAC gnomAD
rs761023877 CA3685583	59	C>G		No	ClinGen ExAC gnomAD
rs771771243 CA362952035	59	C>W		No	ClinGen ExAC gnomAD
rs772799657 CA3685582	59	C>Y		No	ClinGen ExAC gnomAD
rs1449608730 CA362952030	60	Y>C		No	ClinGen gnomAD
CA135894317 rs1048585259	62	E>K		No	ClinGen TOPMed gnomAD
rs931069099 CA135894316	63	T>A		No	ClinGen TOPMed
rs1429970589 CA362951978	64	P>S		No	ClinGen gnomAD
rs768231448 CA3685578	67	R>K		No	ClinGen ExAC gnomAD
rs1184068245 CA362951910	67	R>S		No	ClinGen gnomAD
CA362951889 rs974726070	68	E>D		No	ClinGen TOPMed
CA3685577 rs749282151	71	S>G		No	ClinGen ExAC gnomAD
rs1293360820 CA362951800	73	L>Q		No	ClinGen TOPMed
rs1341797188 CA362951746	78	R>C		No	ClinGen TOPMed
rs780105278 CA3685576	78	R>H		No	ClinGen ExAC TOPMed gnomAD
rs780105278 CA362951736	78	R>L		No	ClinGen ExAC TOPMed gnomAD
CA135894269 rs866296527	79	Q>*		No	ClinGen Ensembl
CA3685575 rs200111516	80	W>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1332178592 CA362951714	80	W>*		No	ClinGen TOPMed
CA362951678 rs1272673216	83	P>A		No	ClinGen gnomAD
rs1397101555 CA362951670	83	P>Q		No	ClinGen gnomAD
rs201936576 CA3685574	85	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1485747489 CA362951622	87	T>A		No	ClinGen TOPMed
TCGA novel	89	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs758680442 CA3685572	89	E>K		No	ClinGen ExAC gnomAD
CA3685571 rs752816648	90	Q>*		No	ClinGen ExAC gnomAD
rs1372025581 CA362951554	92	L>P		No	ClinGen gnomAD
TCGA novel	94	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765350328 CA3685569	97	L>V		No	ClinGen ExAC gnomAD
CA3685568 rs759584881	98	E>*		No	ClinGen ExAC gnomAD
rs759584881 CA362951492	98	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA3685567 rs754412937	99	Q>R		No	ClinGen ExAC gnomAD
rs1170257366 CA362951433	102	T>I		No	ClinGen gnomAD
CA362951403 rs1264506273	105	P>R		No	ClinGen TOPMed
rs1478460432 CA362951381	107	E>*		No	ClinGen TOPMed
CA362951362 rs1417329933	107	E>D		No	ClinGen gnomAD
CA362951351 rs1475622889	108	L>H		No	ClinGen gnomAD
CA362951344 rs766860943	109	Q>P		No	ClinGen ExAC gnomAD
CA3685566 rs766860943	109	Q>R		No	ClinGen ExAC gnomAD
rs1187268644 CA362951328	111	W>C		No	ClinGen TOPMed
rs761032698 CA3685565	111	W>G		No	ClinGen ExAC gnomAD
rs201333721 CA3685564	112	V>L		No	ClinGen ESP ExAC gnomAD
COSM1077170 rs1223749050 CA362951320	113	R>Q	endometrium [Cosmic]	No	ClinGen cosmic curated gnomAD
rs142753390 CA3685562	113	R>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA135894179 rs1029963836	114	E>D		No	ClinGen Ensembl
CA135894186 rs943962836	114	E>K		No	ClinGen TOPMed
TCGA novel	114	E>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761545484 CA3685561	115	H>R		No	ClinGen ExAC gnomAD
CA3685560 rs773848453	117	P>T		No	ClinGen ExAC TOPMed gnomAD
CA3685559 rs768321337	126	L>F		No	ClinGen ExAC
rs912453497 CA135894131	129	D>N		No	ClinGen TOPMed
rs1351746913 CA362951166	130	L>F		No	ClinGen gnomAD
rs1287001510 CA362951141	132	R>M		No	ClinGen TOPMed
CA135894129 rs892130831	133	E>*		No	ClinGen gnomAD
rs1233556529 CA362951126	133	E>V		No	ClinGen gnomAD
CA3685557 rs544592187	134	L>P		No	ClinGen 1000Genomes ExAC gnomAD
CA3685556 rs769865059	135	D>V		No	ClinGen ExAC gnomAD
CA362951098 rs1460139353	136	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA3685554 rs781064910	138	R>K		No	ClinGen ExAC gnomAD
CA362951048 rs1562041653	139	Q>R		No	ClinGen Ensembl
CA362950355 rs1321858017	141	V>F		No	ClinGen gnomAD
rs1158065942 CA362950250	147	G>V		No	ClinGen gnomAD
rs868838585 CA135890047	149	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs778255411 CA135890040	150	V>I		No	ClinGen TOPMed gnomAD
rs866561916 CA135890024	152	M>I		No	ClinGen Ensembl
rs1379603191 CA362950201	152	M>V		No	ClinGen TOPMed gnomAD
CA3685540 rs368592703	153	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs409029 CA3685539 VAR_027012	155	M>V		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs769139642 CA3685538	159	D>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1026054382 CA135889992	160	S>F		No	ClinGen Ensembl
rs1347929876 CA362950086	160	S>T		No	ClinGen TOPMed
rs1189204862 CA362950069	161	A>E		No	ClinGen gnomAD
CA362950020 rs1562037301	165	L>F		No	ClinGen Ensembl
CA3685535 rs561089497	167	T>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA3685534 rs756510174	168	Q>L		No	ClinGen ExAC TOPMed gnomAD
CA362949974 rs1362164781	169	L>F		No	ClinGen TOPMed
rs746770904 CA3685533	170	Q>*		No	ClinGen ExAC gnomAD
CA362949956 rs1347679152	171	S>T		No	ClinGen gnomAD
CA3685532 rs777490415	172	M>V		No	ClinGen ExAC TOPMed gnomAD
CA362949860 rs1330699998	177	E>G		No	ClinGen gnomAD
CA3685530 rs146345821	178	C>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs142014967 CA3685529	178	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685528 rs756122575	179	E>D		No	ClinGen ExAC TOPMed gnomAD
rs1038956223 CA135889938	179	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1404394053 CA362949807	181	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA3685526 rs368148700	184	H>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368148700 CA3685527	184	H>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs755514469 CA135889913 CA362949763	184	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA135889926 rs1007399822	184	H>Y		No	ClinGen TOPMed gnomAD
rs373859131 CA135889906	185	P>A		No	ClinGen ESP TOPMed gnomAD
CA3685524 rs751984170	185	P>R		No	ClinGen ExAC gnomAD
CA362949732 rs1416290438	187	Q>H		No	ClinGen TOPMed
TCGA novel	188	D>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362949719 rs1442531385	189	N>S		No	ClinGen gnomAD
CA3685515 rs746884939	190	G>E		No	ClinGen ExAC gnomAD
TCGA novel	190	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1258983360 CA362949712	190	G>W		No	ClinGen gnomAD
CA362949695 rs1185171727	191	S>L		No	ClinGen gnomAD
CA3685514 rs369663166	191	S>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA3685512 rs749558688	199	S>T		No	ClinGen ExAC gnomAD
TCGA novel	200	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362949611 rs1199935785	202	M>T		No	ClinGen TOPMed
rs1206136668 CA362949593	205	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	211	D>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362949518 rs1467676703	211	D>V		No	ClinGen TOPMed
rs1248165868 CA362949507	212	T>I		No	ClinGen TOPMed
CA362949489 rs1581892785	214	E>G		No	ClinGen Ensembl
CA3685511 rs780104784	218	E>V		No	ClinGen ExAC gnomAD
CA362949440 rs1211029143	219	P>A		No	ClinGen gnomAD
CA362949441 rs1211029143	219	P>S		No	ClinGen gnomAD
CA135888237 rs760474088	220	E>Q		No	ClinGen gnomAD
CA3685510 rs139935830	222	M>L		No	ClinGen ESP ExAC gnomAD
TCGA novel	223	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1467673237 CA362949389	223	R>S		No	ClinGen TOPMed
CA135888201 rs371210439	223	R>T		No	ClinGen ESP TOPMed
CA3685509 rs745922884	225	K>N		No	ClinGen ExAC TOPMed gnomAD
rs1393804418 CA362949336	228	R>K		No	ClinGen TOPMed
CA135888172 rs986833376	231	A>P		No	ClinGen TOPMed
CA3685508 rs376666912	232	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1440258855 CA362949237	238	S>G		No	ClinGen TOPMed gnomAD
CA3685506 rs371351534	238	S>T		No	ClinGen ESP ExAC gnomAD
rs752452643 CA362949208	240	N>K		No	ClinGen ExAC TOPMed gnomAD
rs1405675169 CA362949203	241	T>A		No	ClinGen gnomAD
rs758806235 CA3685504	241	T>I		No	ClinGen ExAC gnomAD
CA362949188 rs1162643056	242	K>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA3685503 rs752464562	243	I>L		No	ClinGen ExAC TOPMed gnomAD
rs752464562 CA362949183	243	I>V		No	ClinGen ExAC TOPMed gnomAD
CA362949158 rs1412022508	245	S>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA3685502 rs764788172	247	A>P		No	ClinGen ExAC TOPMed gnomAD
rs1333514268 CA362949103	251	Q>R		No	ClinGen TOPMed
rs185674931 CA3685500	252	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA362949093 rs1200040002	253	I>L		No	ClinGen gnomAD
TCGA novel	256	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs760625203 CA3685498	256	V>M		No	ClinGen ExAC gnomAD
CA362949054 rs1213577647	258	E>G		No	ClinGen gnomAD
CA362949057 rs996717352	258	E>K		No	ClinGen TOPMed gnomAD
CA135888105 rs996717352	258	E>Q		No	ClinGen TOPMed gnomAD
CA3685497 rs773108731	259	A>T		No	ClinGen ExAC gnomAD
rs373418471 CA3685496	263	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs373418471 COSM1319122 CA362949002	263	A>V	Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA3685493 rs775839865	266	E>G		No	ClinGen ExAC TOPMed gnomAD
rs1441398749 CA362948953	267	S>P		No	ClinGen gnomAD
rs1372861243 CA362948935	268	V>A		No	ClinGen gnomAD
CA362948905 rs1345329242	270	Y>*		No	ClinGen gnomAD
CA362948909 rs1440053075	270	Y>C		No	ClinGen gnomAD
CA135888032 rs998813719	271	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs769921503 CA3685491 COSM1496316	271	R>H	kidney [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs200083378 CA135888030	272	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA TOPMed gnomAD
rs746033700 CA3685490	281	V>E		No	ClinGen ExAC gnomAD
CA135888028 rs1000971684	281	V>I		No	ClinGen TOPMed
rs1193619647 CA362948763	283	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA362948751 rs1244274375	284	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA3685489 rs781160168	284	N>Y		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	285	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362948737 rs1316557206	285	E>G		No	ClinGen TOPMed
CA135888024 rs371868572	285	E>K		No	ClinGen ESP
CA3685488 rs771115235	286	K>N		No	ClinGen ExAC gnomAD
rs747560441 CA3685487	288	I>T		No	ClinGen ExAC TOPMed gnomAD
CA3685485 rs758890813	290	A>V		No	ClinGen ExAC gnomAD
CA3685484 rs759614062	293	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1160608210 CA362948637	294	E>*		No	ClinGen gnomAD
rs757103662	294	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA3685479 rs375395139	296	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs754620574 CA3685481	296	D>G		No	ClinGen ExAC gnomAD
rs999282193 CA135887950	297	K>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA135887939 rs1055423005	299	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs760144567 CA3685478	299	R>W		No	ClinGen ExAC gnomAD
rs1581892208 CA362948528	303	H>N		No	ClinGen Ensembl
CA362948501 rs767425005	304	S>R		No	ClinGen ExAC TOPMed gnomAD
CA362948486 rs1485608358	305	E>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs761681576 CA3685475	306	D>G		No	ClinGen ExAC gnomAD
CA3685474 rs774020117	307	L>V		No	ClinGen ExAC gnomAD
rs1257370499 CA362948454	308	F>S		No	ClinGen TOPMed
rs1474530825 CA362948448	309	D>N		No	ClinGen TOPMed
rs903639192 CA135887869	309	D>V		No	ClinGen gnomAD
rs768456437 CA3685473	312	H>R		No	ClinGen ExAC gnomAD
rs759406637 CA135887859	313	N>D		No	ClinGen Ensembl
TCGA novel	313	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362948360 rs1449624597	316	L>F		No	ClinGen Ensembl
rs759726961 CA3685472	317	S>N		No	ClinGen ExAC TOPMed gnomAD
CA3685471 rs776883621	318	I>T		No	ClinGen ExAC gnomAD
CA3685469 rs371350479	320	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685468 rs550481256	323	R>C		No	ClinGen 1000Genomes ExAC gnomAD
rs772714508 CA3685467	323	R>H		No	ClinGen ExAC TOPMed gnomAD
rs748650522 CA3685466	325	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA3685465 rs779170818	325	R>H		No	ClinGen ExAC TOPMed gnomAD
CA362948297 rs779170818	325	R>L		No	ClinGen ExAC TOPMed gnomAD
rs755344120 CA3685464	326	M>I		No	ClinGen ExAC gnomAD
CA362948255 rs1356610828	331	Q>*		No	ClinGen gnomAD
rs1169018629 CA362948246 COSM375091	332	A>V	lung [Cosmic]	No	ClinGen cosmic curated gnomAD
rs779673023 CA3685462	334	Y>*		No	ClinGen ExAC gnomAD
CA135887795 rs947768579	335	K>E		No	ClinGen TOPMed gnomAD
rs755675151 CA3685461	338	T>I		No	ClinGen ExAC gnomAD
CA362948177 rs1183125354	342	I>L		No	ClinGen gnomAD
rs1183125354 CA362948178	342	I>V		No	ClinGen gnomAD
CA362948166 rs1480862945	343	M>I		No	ClinGen gnomAD
CA3685459 rs766946778	343	M>V		No	ClinGen ExAC TOPMed
rs1280952360 CA362948137	348	L>F		No	ClinGen gnomAD
TCGA novel	356	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs367554363 CA3685456	358	K>E		No	ClinGen ESP ExAC gnomAD
rs144011793 CA3685455	359	L>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144011793 CA3685454	359	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	363	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA135887684 rs920913397	367	S>L		No	ClinGen TOPMed
CA3685452 rs374821729	368	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs866308071 CA135887680	370	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs760916497 CA135887672	372	S>N		No	ClinGen ExAC TOPMed gnomAD
CA3685450 rs760916497	372	S>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	373	S>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362947857 rs1562034219	374	R>*		No	ClinGen Ensembl
rs1167680955 CA362947794	379	L>V		No	ClinGen gnomAD
CA362947780 rs762661768	380	I>R		No	ClinGen TOPMed gnomAD
rs762661768 CA135887667	380	I>T		No	ClinGen TOPMed gnomAD
rs564571708 CA3685448	382	M>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs146240881 CA3685447	383	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362947708 rs1581891728	386	P>T		No	ClinGen Ensembl
CA362947651 rs1457119178	391	R>G		No	ClinGen gnomAD
CA362947645 rs1253581700	391	R>I		No	ClinGen gnomAD
TCGA novel	391	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA135887640 rs975332566	391	R>S		No	ClinGen TOPMed
TCGA novel	392	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685446 rs774887211	395	H>R		No	ClinGen ExAC gnomAD
TCGA novel	397	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs866166600 CA135887623	397	Q>P		No	ClinGen Ensembl
rs749647571 CA3685443	398	D>E		No	ClinGen ExAC TOPMed gnomAD
CA3685445 rs768966129	398	D>H		No	ClinGen ExAC gnomAD
TCGA novel	398	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs941196760 CA135887602	399	L>F		No	ClinGen Ensembl
rs112217331 CA135887601	401	T>A		No	ClinGen Ensembl
CA362947478 rs1304350780	401	T>R		No	ClinGen TOPMed gnomAD
rs752273361 CA3685442	404	T>S		No	ClinGen ExAC gnomAD
rs185476387 CA3685437	407	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs866662971 CA135887569	407	R>W		No	ClinGen gnomAD
CA3685436 rs751519787	412	K>E		No	ClinGen ExAC gnomAD
rs557568739 CA3685435	415	T>M		No	ClinGen 1000Genomes ExAC gnomAD
rs138636417 CA135887562	417	V>I		No	ClinGen ESP TOPMed
rs765088315 CA362947151	419	H>P		No	ClinGen ExAC gnomAD
CA3685432 rs765088315	419	H>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA362947119 rs1257038169	421	L>F		No	ClinGen TOPMed
CA362947090 rs1195486893	423	D>V		No	ClinGen gnomAD
CA135887561 rs1033666951	426	T>R		No	ClinGen TOPMed gnomAD
CA3685431 rs761002813	428	I>T		No	ClinGen ExAC TOPMed gnomAD
CA3685430 rs773549282	429	G>E		No	ClinGen ExAC gnomAD
rs767742393 CA3685429	430	A>T		No	ClinGen ExAC gnomAD
rs1349118678 CA362947012	432	S>G		No	ClinGen gnomAD
rs1306073049 CA362947010	432	S>N		No	ClinGen gnomAD
CA3685427 rs774775040	433	V>I		No	ClinGen ExAC gnomAD
CA362946993 rs1370922547	435	Q>*		No	ClinGen gnomAD
CA135887531 rs1002468162	435	Q>P		No	ClinGen TOPMed
CA135887522 rs267600930	436	S>F		No	ClinGen Ensembl
CA3685426 rs769216803	438	N>S		No	ClinGen ExAC gnomAD
CA362946948 rs1382847567	441	E>D		No	ClinGen gnomAD
COSM164189 CA362946927 rs1288566361	444	S>R	breast [Cosmic]	No	ClinGen cosmic curated gnomAD
rs368184338 CA3685424	445	Q>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685425 rs368184338	445	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1395530377 CA362946911	447	V>F		No	ClinGen gnomAD
rs1395530377 CA362946913	447	V>I		No	ClinGen gnomAD
rs746429038 CA135887498	453	I>T		No	ClinGen TOPMed gnomAD
TCGA novel	453	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1581891280 CA362946860	454	W>*		No	ClinGen Ensembl
rs745568755 CA3685422	454	W>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA
CA362946850 rs1377032378	455	P>L		No	ClinGen gnomAD
TCGA novel	456	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685420 rs770407328	461	H>R		No	ClinGen ExAC TOPMed gnomAD
rs777082620 CA3685418	463	K>N		No	ClinGen ExAC gnomAD
CA3685417 rs758395687	464	S>A		No	ClinGen ExAC gnomAD
CA135887465 rs1031917813	464	S>Y		No	ClinGen gnomAD
rs1344707009 CA362946784	465	Q>H		No	ClinGen gnomAD
CA3685416 rs41270593 VAR_061703	465	Q>K		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA3685414 rs754792535	467	C>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1168506788 CA362946743	471	S>C		No	ClinGen TOPMed
CA3685413 rs376727708	472	S>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA3685409 rs200493151	480	R>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs763539074 CA3685408	480	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1388841226 CA362946677	481	K>E		No	ClinGen TOPMed
CA3685407 rs775952071	481	K>M		No	ClinGen ExAC gnomAD
rs1051313452 CA135887416	485	S>C		No	ClinGen TOPMed gnomAD
rs776922995 CA3685404	487	M>I		No	ClinGen ExAC gnomAD
CA3685403 rs770622275	490	N>S		No	ClinGen ExAC TOPMed gnomAD
rs151305850 CA3685402	491	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA362946603 rs1259224285	491	N>S		No	ClinGen gnomAD
TCGA novel	493	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770949657 CA3685398	494	H>R		No	ClinGen ExAC gnomAD
CA3685399 rs748139014	494	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA3685397 rs754876151	495	W>*		No	ClinGen ExAC gnomAD
CA3685396 rs753695405	497	E>*		No	ClinGen ExAC TOPMed gnomAD
CA362946559 rs1489605733	498	F>I		No	ClinGen TOPMed
rs897120207 CA135887343	499	L>F		No	ClinGen Ensembl
rs1267759283 CA362946546	500	W>R		No	ClinGen TOPMed
CA3685393 rs751683471	501	F>L		No	ClinGen ExAC gnomAD
rs1414384320 CA362946534	501	F>S		No	ClinGen gnomAD
CA362946250 rs1329299227	509	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA362946251 rs1329299227	509	P>R		No	ClinGen TOPMed gnomAD
rs267600929 CA135887304	509	P>S		No	ClinGen Ensembl
rs762987939 CA3685390	514	M>T		No	ClinGen ExAC gnomAD
CA362946210 rs1461548057	515	Q>K		No	ClinGen gnomAD
TCGA novel	515	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753262940 CA3685389	517	T>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	517	T>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765749262 CA3685388	518	P>A		No	ClinGen ExAC gnomAD
CA3685387 rs759969184	518	P>L		No	ClinGen ExAC TOPMed gnomAD
CA135887244 rs925836938	519	C>Y		No	ClinGen TOPMed
rs941227808 CA135887243	522	A>T		No	ClinGen Ensembl
TCGA novel	522	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685385 rs771155248	523	F>L		No	ClinGen ExAC gnomAD
rs1238135484 CA362946137	525	S>F		No	ClinGen TOPMed gnomAD
rs1214838755 CA362946135	526	E>Q		No	ClinGen gnomAD
CA362946131 rs1562033313	526	E>V		No	ClinGen Ensembl
rs200974575 CA3685384	527	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA362946093 rs1361686923	532	S>C		No	ClinGen TOPMed
rs1227744849 CA362946063	537	T>A		No	ClinGen gnomAD
CA3685382 rs771683030	538	E>K		No	ClinGen ExAC gnomAD
rs1281437563 CA362946046	539	E>V		No	ClinGen gnomAD
CA3685381 rs762657554	541	V>A		No	ClinGen ExAC gnomAD
CA362946037 rs1444146624	541	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1444146624 CA362946036	541	V>L		No	ClinGen gnomAD
rs773937865 CA3685380	543	S>N		No	ClinGen ExAC gnomAD
rs12193707 CA135887219	543	S>R		No	ClinGen Ensembl
rs1441531871 CA362946016	544	L>W		No	ClinGen gnomAD
TCGA novel	547	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362945979 rs1581890604	549	E>G		No	ClinGen Ensembl
CA3685379 rs768715221	550	L>F		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	555	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685378 rs373152552	556	E>K		No	ClinGen ESP ExAC gnomAD
rs779921307 CA3685377	556	E>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	558	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362945916 rs1159899723	558	E>K		No	ClinGen gnomAD
CA362945909 rs1232701513	559	N>D		No	ClinGen TOPMed
rs777997535 CA3685375	561	L>*		No	ClinGen ExAC gnomAD
rs777997535 CA135887157	561	L>S		No	ClinGen ExAC gnomAD
rs755842509 CA3685376	561	L>V		No	ClinGen ExAC gnomAD
COSM1077159 rs777852841 CA3685374	562	R>K	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs752780762 CA3685372	563	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1332998480 CA362945880	564	Q>E		No	ClinGen gnomAD
CA3685371 rs765262452	564	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs866451020 CA135887104	566	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
TCGA novel	567	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1165808028 CA362945853	567	E>D		No	ClinGen gnomAD
CA3685370 rs755505254	567	E>V		No	ClinGen ExAC TOPMed gnomAD
rs754280984 CA3685369	569	I>T		No	ClinGen ExAC gnomAD
CA362945828 rs1562033068	571	T>S		No	ClinGen Ensembl
CA135887089 rs967653222	572	G>A		No	ClinGen TOPMed
rs967653222 CA362945820	572	G>V		No	ClinGen TOPMed
TCGA novel	573	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362945809 rs1478126401	574	D>G		No	ClinGen TOPMed
rs1265181705 CA362945813	574	D>N		No	ClinGen TOPMed
rs1181252056 CA362945803	575	S>C		No	ClinGen TOPMed
rs1308257232 CA362945796	576	S>G		No	ClinGen gnomAD
CA135887082 rs1024123074	576	S>R		No	ClinGen TOPMed
rs766810900 CA3685366	578	I>T		No	ClinGen ExAC gnomAD
CA135887077 rs1049854045	578	I>V		No	ClinGen TOPMed gnomAD
TCGA novel	580	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs567149204 CA3685364	582	L>P		No	ClinGen 1000Genomes ExAC gnomAD
rs1418348852 CA362945751	582	L>V		No	ClinGen gnomAD
rs992680765 CA135887073	584	V>A		No	ClinGen TOPMed
CA362945727 rs1359504265	586	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs761488932 CA3685362	587	K>R		No	ClinGen ExAC gnomAD
CA3685361 rs774026940	589	A>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	590	E>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685360 rs768231258	590	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1189764003	592	S>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362945664 rs1300459216	595	E>D		No	ClinGen TOPMed
CA362945667 rs1174671812	595	E>G		No	ClinGen gnomAD
CA362945656 rs960751056 CA135887024	596	S>R		No	ClinGen TOPMed
CA362945651 rs1301664543	597	R>K		No	ClinGen TOPMed
rs749285848 CA3685359	599	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1484678340 CA362945633	600	F>S		No	ClinGen gnomAD
CA362945623 rs1228964560	601	L>F		No	ClinGen TOPMed
rs267600928 CA135887018	602	S>F		No	ClinGen Ensembl
CA3685358 rs377354714	603	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs1209587239 CA362945610	604	V>I		No	ClinGen gnomAD
rs1475812728 CA362945601	605	V>A		No	ClinGen gnomAD
CA3685357 rs769697195	605	V>L		No	ClinGen ExAC TOPMed gnomAD
CA3685356 rs373843219	607	E>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs932687363 CA362945572	609	E>A		No	ClinGen TOPMed
CA135887000 rs932687363	609	E>V		No	ClinGen TOPMed
CA135886993 rs143317108	612	G>D		No	ClinGen ESP
CA362945554 rs1581890105	612	G>R		No	ClinGen Ensembl
CA3685352 rs376105981	613	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs754439812 CA3685350	615	S>N		No	ClinGen ExAC gnomAD
rs865851767 CA135886970	616	C>R		No	ClinGen Ensembl
CA3685349 rs766785848	616	C>W		No	ClinGen ExAC
rs1181955211 CA362945520	617	I>T		No	ClinGen TOPMed
CA135886943 rs962696499	622	N>D		No	ClinGen TOPMed
CA362945479 rs1362125099	623	I>N		No	ClinGen gnomAD
rs1271436330 CA362945446	628	G>R		No	ClinGen gnomAD
rs1397524400 CA362945426	631	S>P		No	ClinGen TOPMed gnomAD
CA362945411 rs1317474044	633	H>P		No	ClinGen TOPMed gnomAD
CA3685348 rs750752782	633	H>Q		No	ClinGen ExAC gnomAD
rs1317474044 CA362945410	633	H>R		No	ClinGen TOPMed gnomAD
TCGA novel	634	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1332688410 CA362945393	636	E>K		No	ClinGen TOPMed
rs767951243 COSM227495 CA3685346	637	G>S	skin [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs1017644371 CA135886929	639	G>S		No	ClinGen TOPMed gnomAD
CA3685344 rs774123229	640	R>Q		No	ClinGen ExAC gnomAD
CA3685345 rs761577088	640	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA362945339 rs1448786052	644	C>W		No	ClinGen TOPMed
rs368567492 CA3685342	644	C>Y		No	ClinGen ESP ExAC gnomAD
rs769624595 CA3685340	646	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1258527312 CA362945280	653	M>V		No	ClinGen TOPMed gnomAD
CA362945266 rs370520 CA362945265	654	K>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs192789581 CA3685338	655	R>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs529862162 CA3685337	657	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1276351896 CA362945239	658	D>A		No	ClinGen TOPMed
rs1562032557 CA362945229	659	E>D		No	ClinGen Ensembl
CA362945235 rs1209082226	659	E>K		No	ClinGen gnomAD
rs779106641 CA3685335	660	I>F		No	ClinGen ExAC gnomAD
CA3685336 rs779106641	660	I>L		No	ClinGen ExAC gnomAD
rs114011801 CA3685334	664	L>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs754946886 CA135886905	669	S>C		No	ClinGen TOPMed
CA362945163 rs754946886	669	S>F		No	ClinGen TOPMed
TCGA novel	671	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1377527429 CA362945120	676	G>R		No	ClinGen gnomAD
CA3685331 rs149460983	677	T>A		No	ClinGen 1000Genomes ExAC gnomAD
rs542386571 CA135886861	678	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA TOPMed gnomAD
CA135886851 rs1012007599	681	P>L		No	ClinGen TOPMed
CA3685330 rs750890929	682	D>H		No	ClinGen ExAC gnomAD
rs781723137 CA3685329	683	K>E		No	ClinGen ExAC TOPMed
CA362945052 rs450630	686	D>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1034773994 CA135886830	687	W>*		No	ClinGen TOPMed
CA135886339 rs901018518	688	M>T		No	ClinGen Ensembl
CA362945030 rs1368146817	688	M>V		No	ClinGen TOPMed gnomAD
CA362945018 rs1160057704	689	A>V		No	ClinGen gnomAD
CA362944987 rs1176771322	694	L>P		No	ClinGen gnomAD
CA3685316 rs768761726	695	D>N		No	ClinGen ExAC TOPMed gnomAD
CA362944969 rs1289554416	697	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA3685315 rs749481956	698	V>F		No	ClinGen ExAC gnomAD
rs1562031803 CA362944955	699	K>E		No	ClinGen Ensembl
rs1376129023 CA362944929	702	H>R		No	ClinGen gnomAD
CA362944922 rs998682189	703	A>G		No	ClinGen TOPMed gnomAD
rs998682189 CA135886298	703	A>V		No	ClinGen TOPMed gnomAD
TCGA novel	707	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362944887 rs1487198562	708	S>N		No	ClinGen gnomAD
CA362944882 rs1191478668	709	S>R		No	ClinGen TOPMed
rs1421010078 CA362944871	710	S>N		No	ClinGen TOPMed
rs1264536392 CA362944863	711	N>S		No	ClinGen gnomAD
rs780017982 CA3685314	715	V>A		No	ClinGen ExAC gnomAD
rs1163549144 CA362944822	717	N>Y		No	ClinGen TOPMed
rs749299834 CA3685312	721	P>R		No	ClinGen ExAC gnomAD
TCGA novel	723	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685311 rs781762980	723	E>K		No	ClinGen ExAC gnomAD
rs1445386609 CA362944774	723	E>V		No	ClinGen gnomAD
rs903309112 CA135886244	726	T>I		No	ClinGen Ensembl
TCGA novel	727	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685310 rs757754219	727	K>R		No	ClinGen ExAC TOPMed gnomAD
rs1306214726 CA362944733	729	V>A		No	ClinGen gnomAD
rs1385199375 CA362944717	732	S>G		No	ClinGen gnomAD
rs778243531 CA3685308	735	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs751985909 CA3685309	735	R>W		No	ClinGen ExAC TOPMed gnomAD
rs758010103 CA3685307	737	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA362944672 rs1358786818	738	D>E		No	ClinGen gnomAD
rs1327505078 CA362944665	739	P>L		No	ClinGen TOPMed gnomAD
rs1156629960 CA362944663	740	S>P		No	ClinGen gnomAD
rs146781571 CA3685305	742	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs752375309 CA3685306	742	I>V		No	ClinGen ExAC gnomAD
rs373445500 CA3685303	744	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs894449718 CA135886179	747	V>A		No	ClinGen Ensembl
rs1562031552 CA362944582	752	G>D		No	ClinGen Ensembl
rs137872757 CA3685302	752	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs760535272 CA3685301	754	V>I		No	ClinGen ExAC gnomAD
CA3685299 rs201359181	758	Q>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA3685298 rs763130489	758	Q>H		No	ClinGen ExAC
CA3685296 rs368697738	765	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1180797926 CA362944451	771	M>I		No	ClinGen TOPMed
rs1159510258 CA362944447	772	K>T		No	ClinGen TOPMed gnomAD
rs771597767 CA3685293	773	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
COSM1077155 rs747470312 CA3685292	778	R>*	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs150277871 COSM173896 CA3685291	778	R>Q	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs747825138 CA3685289	781	Y>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1418914824 CA362944380	782	S>*		No	ClinGen gnomAD
TCGA novel	783	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362944343 rs1174308088	787	I>R		No	ClinGen TOPMed gnomAD
TCGA novel	788	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA135886105 rs983266022 COSM1077154	794	F>L	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA362944268 rs1193303723	797	R>T		No	ClinGen gnomAD
rs756349242 CA135886101	800	S>T		No	ClinGen Ensembl
CA3685286 rs748371281	805	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA3685285 rs376518990	807	K>E		No	ClinGen ESP ExAC gnomAD
CA135886089 rs200971932	808	Q>E		No	ClinGen gnomAD
rs200971932 CA362944191	808	Q>K		No	ClinGen gnomAD
rs1381489347 CA362944184	809	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA3685283 rs756063944	811	N>D		No	ClinGen ExAC gnomAD
CA3685282 rs563376661	811	N>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1453637748 CA362944167	811	N>T		No	ClinGen TOPMed
CA3685280 rs150565596	812	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1237704087 CA362944146	814	H>Q		No	ClinGen TOPMed
rs781012024 CA3685279	815	I>V		No	ClinGen ExAC gnomAD
TCGA novel	819	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685277 rs373276293	819	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685273 rs747560340	821	R>L		No	ClinGen ExAC gnomAD
CA3685274 rs747560340	821	R>Q		No	ClinGen ExAC gnomAD
COSM1642973 rs199908707 CA3685275	821	R>W	Variant assessed as Somatic; 0.0 impact. stomach [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs564677406 CA3685272	822	A>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362944101 rs564677406	822	A>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362944102 rs564677406	822	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362944071 rs1168391333	826	V>A		No	ClinGen gnomAD
rs748562566 CA3685270	828	L>F		No	ClinGen ExAC gnomAD
rs142639079 CA135885977 COSM303157	829	P>L	Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP NCI-TCGA TOPMed gnomAD
rs754652587 CA3685268	831	A>S		No	ClinGen ExAC TOPMed gnomAD
rs754652587 CA362944047	831	A>T		No	ClinGen ExAC TOPMed gnomAD
CA362944043 rs1179347946	831	A>V		No	ClinGen TOPMed
rs748887749 CA3685267	832	K>R		No	ClinGen ExAC gnomAD
CA135885950 rs201449726	836	P>S		No	ClinGen Ensembl
rs755587318 CA3685265	838	T>A		No	ClinGen ExAC gnomAD
rs1456549590 CA362943944	846	D>E		No	ClinGen gnomAD
CA362943942 rs1257504256	847	C>R		No	ClinGen gnomAD
rs1233906347 CA362943934	848	I>L		No	ClinGen gnomAD
rs1233906347 CA362943935	848	I>V		No	ClinGen gnomAD
CA135885943 rs964233763	849	K>E		No	ClinGen TOPMed
CA135885942 rs201001683	853	L>S		No	ClinGen 1000Genomes TOPMed
TCGA novel	857	G>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	857	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751373949 CA3685261	860	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA362943832 rs1329527480	862	K>N		No	ClinGen gnomAD
TCGA novel	863	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362943811 rs1448898280	865	A>V		No	ClinGen gnomAD
TCGA novel	866	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362943785 rs1374981736	869	L>P		No	ClinGen TOPMed
CA362943779 rs1239972042	870	S>F		No	ClinGen gnomAD
CA362943774 rs1330106072	871	N>S		No	ClinGen gnomAD
rs763747464 CA362943758	873	T>I		No	ClinGen ExAC gnomAD
CA3685260 rs763747464	873	T>S		No	ClinGen ExAC gnomAD
rs142877647 CA3685259	874	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs541386862 CA3685258 COSM1077153	876	R>Q	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA3685257 rs766635355	877	R>C		No	ClinGen ExAC gnomAD
CA135885929 rs766635355	877	R>G		No	ClinGen ExAC gnomAD
CA3685256 rs572680396	877	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362943737 rs1181136488	878	I>V		No	ClinGen gnomAD
CA3685254 rs772641291	882	A>V		No	ClinGen ExAC gnomAD
rs1214427947 CA362943700	883	N>I		No	ClinGen TOPMed gnomAD
rs998713311 CA135885908	885	M>T		No	ClinGen TOPMed
CA362943666 rs1324990945	887	D>E		No	ClinGen TOPMed
CA362943648 rs1209449103	890	I>T		No	ClinGen gnomAD
rs774796991 CA3685252	890	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	891	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685251 rs138676911	893	I>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs369649396 CA135885902	895	L>P		No	ClinGen ESP
CA362943606 rs1309719695	896	A>G		No	ClinGen TOPMed gnomAD
CA362943576 rs1241975317	900	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA362943559 rs779674912	903	L>F		No	ClinGen ExAC TOPMed gnomAD
CA3685248 rs769349447	903	L>R		No	ClinGen ExAC gnomAD
CA3685249 rs779674912	903	L>V		No	ClinGen ExAC TOPMed gnomAD
CA362943537 rs1432638426	906	C>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1358322679 CA362943532	907	R>G		No	ClinGen gnomAD
rs745394917 CA3685247	908	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA3685246 rs780500503	910	A>G		No	ClinGen ExAC gnomAD
CA362943511 rs1189916536	910	A>T		No	ClinGen TOPMed
CA3685245 rs757249850	911	N>D		No	ClinGen ExAC gnomAD
rs376579572 CA135885849	912	M>L		No	ClinGen ESP TOPMed gnomAD
CA3685244 rs751429782	913	I>V		No	ClinGen ExAC gnomAD
rs777751804 CA3685243	914	I>L		No	ClinGen ExAC gnomAD
rs541816467 CA3685242	916	L>V		No	ClinGen 1000Genomes ExAC gnomAD
CA362943465 rs1438176441	917	V>F		No	ClinGen gnomAD
rs766723549 CA3685240	918	Y>C		No	ClinGen ExAC gnomAD
CA3685241 rs754173115	918	Y>H		No	ClinGen ExAC gnomAD
rs371912682 CA135885790	919	V>M		No	ClinGen ESP TOPMed gnomAD
CA135885789 rs112370819	920	R>G		No	ClinGen Ensembl
TCGA novel	922	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs760916515 CA3685238	923	H>R		No	ClinGen ExAC gnomAD
CA3685237 rs750552121	924	D>E		No	ClinGen ExAC TOPMed gnomAD
rs767442848 CA3685236	926	D>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	928	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA566284129 rs1491209634	932	F>I		No	ClinGen gnomAD
CA3685235 rs762427961	935	A>T		No	ClinGen ExAC gnomAD
CA362943328 rs1266926620	936	S>F		No	ClinGen TOPMed gnomAD
CA362943330 rs1266926620	936	S>Y		No	ClinGen TOPMed gnomAD
rs769073471 CA3685233	938	P>L		No	ClinGen ExAC gnomAD
CA3685232 rs763289698	940	N>S		No	ClinGen ExAC gnomAD
rs1281242264 CA362943300	941	T>S		No	ClinGen TOPMed
CA3685231 rs192141084	942	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362943296 rs192141084	942	T>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	944	S>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362943260 rs1418304434	947	Y>C		No	ClinGen gnomAD
rs745470348 CA3685229	950	V>A		No	ClinGen ExAC gnomAD
CA362943230 COSM3430417 rs1261405055	951	K>N	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA362943216 rs1315587404	953	Y>S		No	ClinGen TOPMed
rs780803534 CA3685228 CA362943194	956	N>K		No	ClinGen ExAC TOPMed gnomAD
CA362943190 rs1451334018	957	K>T		No	ClinGen TOPMed
rs770317152 CA3685227	958	C>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA362943183 rs1281890003	958	C>Y		No	ClinGen TOPMed gnomAD
rs1265668816 CA362943174	959	G>A		No	ClinGen TOPMed gnomAD
rs1265668816 CA362943175	959	G>D		No	ClinGen TOPMed gnomAD
rs375502311 CA135885701	963	K>E		No	ClinGen Ensembl
rs1191755167 CA362943126	966	V>I		No	ClinGen gnomAD
CA3685225 rs777841694	968	V>I		No	ClinGen ExAC TOPMed gnomAD
CA135885697 rs147729602	971	D>A		No	ClinGen 1000Genomes gnomAD
rs941909569 CA135885696	973	A>T		No	ClinGen TOPMed gnomAD
rs758355326 CA3685224	974	A>V		No	ClinGen ExAC gnomAD
CA3685223 rs747964848	976	M>V		No	ClinGen ExAC gnomAD
rs778815445 CA3685222	977	T>R		No	ClinGen ExAC gnomAD
CA3685221 rs756385802	979	K>E		No	ClinGen ExAC TOPMed gnomAD
CA3685220 rs147087175	980	H>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA362943028 rs1450571512	981	S>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1303806449 CA362943033	981	S>T		No	ClinGen gnomAD
rs1357958442 CA362943026	982	E>Q		No	ClinGen gnomAD
CA135885672 rs930036685	986	Q>*		No	ClinGen TOPMed
CA135885669 rs867739512	989	E>K		No	ClinGen Ensembl
rs141069135 CA3685217	991	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs150320923 CA3685218	991	A>S		No	ClinGen ESP ExAC gnomAD
CA3685216 rs141069135 COSM1077149	991	A>V	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs976696672 CA135885640	993	E>G		No	ClinGen TOPMed
rs1484091009 CA362942930	996	T>I		No	ClinGen gnomAD
rs1209317532 CA362942921	998	H>D		No	ClinGen gnomAD
CA3685213 rs765536819	998	H>L		No	ClinGen ExAC TOPMed gnomAD
rs751419889 CA135885632	1002	H>D		No	ClinGen TOPMed gnomAD
CA3685211 rs759273140	1002	H>R		No	ClinGen ExAC TOPMed gnomAD
rs267600926 CA135885626	1003	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA362942884 rs1294374094	1003	R>Q		No	ClinGen TOPMed
rs1312936565 CA362942879	1004	E>A		No	ClinGen gnomAD
rs776144995 CA3685210	1006	L>I		No	ClinGen ExAC gnomAD
rs746517243 CA3685208	1007	A>D		No	ClinGen ExAC gnomAD
CA135885621 rs1036552946	1007	A>T		No	ClinGen Ensembl
rs369960728 CA362942856	1008	M>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685207 rs369960728	1008	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685206 rs571375385	1009	K>E		No	ClinGen 1000Genomes ExAC gnomAD
CA362942846 rs1329415379	1009	K>R		No	ClinGen gnomAD
TCGA novel	1010	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685205 rs202191570	1011	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA362942826 rs1237083234	1012	S>A		No	ClinGen TOPMed
rs754694007 CA3685202	1014	E>K		No	ClinGen ExAC TOPMed gnomAD
rs754694007 CA362942816	1014	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA362942800 rs1562030239	1016	N>S		No	ClinGen Ensembl
rs1425068182 CA823648354	1017	S>K		No	ClinGen TOPMed
rs1440252678 CA362942791	1017	S>N		No	ClinGen gnomAD
CA135885570 rs979415568	1017	S>R		No	ClinGen TOPMed gnomAD
rs968937923 CA135885567	1019	L>F		No	ClinGen TOPMed
CA135885566 rs931037978	1022	I>R		No	ClinGen Ensembl
rs757440181 CA3685199	1025	I>L		No	ClinGen ExAC TOPMed gnomAD
CA3685198 rs201118541	1027	N>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA3685196 rs200192395	1027	N>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs959754321 CA135885539	1029	I>M		No	ClinGen TOPMed
rs868370764 CA135885532	1033	S>L		No	ClinGen Ensembl
rs867873595 CA135885527	1036	S>L		No	ClinGen Ensembl
rs377545578 CA135885521	1037	R>G		No	ClinGen ESP TOPMed
rs1320365830 CA362942660	1037	R>I		No	ClinGen gnomAD
CA362942661 rs1320365830	1037	R>T		No	ClinGen gnomAD
CA3685195 rs535454300	1040	S>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs749944224 CA135885519	1043	C>R		No	ClinGen Ensembl
CA135885518 CA3685194 rs145912647	1049	D>E		No	ClinGen ESP ExAC gnomAD
rs1307661298 CA362942573	1049	D>G		No	ClinGen gnomAD
rs1239897307 CA362942568	1050	H>R		No	ClinGen TOPMed
rs1295575508 CA362942532	1055	L>P		No	ClinGen gnomAD
CA362942527 rs1258849297	1056	H>P		No	ClinGen gnomAD
TCGA novel	1058	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776998149 CA3685192	1059	I>V		No	ClinGen ExAC gnomAD
CA3685190 rs760366616	1060	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs765954782 COSM1077148 CA3685191	1060	R>W	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1176675800 CA362942496	1061	W>*		No	ClinGen TOPMed gnomAD
rs146788972 CA3685188	1064	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA3685189 rs772875546	1064	R>W		No	ClinGen ExAC TOPMed gnomAD
CA3685187 rs774422230	1067	V>F		No	ClinGen ExAC TOPMed gnomAD
CA3685186 rs774422230	1067	V>L		No	ClinGen ExAC TOPMed gnomAD
rs768550704 CA3685185	1068	L>V		No	ClinGen ExAC gnomAD
CA362942443 rs1361889470	1070	R>T		No	ClinGen TOPMed
rs1217851293 CA362942438	1071	M>V		No	ClinGen gnomAD
rs1455263971 CA362942426	1072	F>S		No	ClinGen TOPMed
CA3685183 rs779833593	1073	E>G		No	ClinGen ExAC gnomAD
TCGA novel	1073	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362942415 rs1159135980	1074	I>L		No	ClinGen TOPMed
COSM1077147 CA3685182 rs143546833	1075	R>*	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA362942406 rs1240047379 COSM3623805	1075	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs149136448 CA3685181	1076	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
COSM3777422 CA135885423 rs868501361	1077	E>K	Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated Ensembl NCI-TCGA
rs1303514217 CA362942390	1078	L>F		No	ClinGen gnomAD
rs1385102830 CA362942383	1079	L>V		No	ClinGen gnomAD
rs1406393337 CA362942373	1080	V>E		No	ClinGen TOPMed
CA362942367 rs1367206932	1081	F>S		No	ClinGen gnomAD
TCGA novel	1082	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA135885420 rs865936980	1084	G>S		No	ClinGen Ensembl
TCGA novel	1084	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1298996316 CA362942344	1085	K>E		No	ClinGen gnomAD
rs777879220 CA3685180	1085	K>R		No	ClinGen ExAC gnomAD
TCGA novel	1086	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362942309 rs1156848753	1089	W>*		No	ClinGen TOPMed gnomAD
CA362942307 rs1156848753	1089	W>C		No	ClinGen TOPMed gnomAD
TCGA novel	1090	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1090	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685177 rs779299649	1093	F>L		No	ClinGen ExAC gnomAD
rs201770579 CA3685175	1094	K>E		No	ClinGen 1000Genomes ExAC
CA362942268 rs766714456	1095	D>G		No	ClinGen ExAC gnomAD
CA3685174 rs766714456	1095	D>V		No	ClinGen ExAC gnomAD
rs760448501 CA3685173	1096	V>M		No	ClinGen ExAC gnomAD
rs1562029849 CA362942258	1097	N>Y		No	ClinGen Ensembl
CA362942241 rs1261480452	1099	T>S		No	ClinGen gnomAD
CA362942237 rs1204858672	1100	A>S		No	ClinGen gnomAD
rs767206859 CA3685170	1104	Y>F		No	ClinGen ExAC TOPMed gnomAD
rs750074334 CA3685171	1104	Y>H		No	ClinGen ExAC TOPMed gnomAD
rs368224878 CA3685169	1105	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685168 rs773856808	1107	D>G		No	ClinGen ExAC gnomAD
rs1310491000 CA362942169	1110	S>N		No	ClinGen gnomAD
CA3685165 rs762908967	1114	D>N		No	ClinGen ExAC gnomAD
CA3685166 rs762908967	1114	D>Y		No	ClinGen ExAC gnomAD
TCGA novel	1115	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1115	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362942118 rs1338623454	1117	A>V		No	ClinGen gnomAD
rs886300295 CA135885382	1119	M>V		No	ClinGen TOPMed gnomAD
CA362942093 rs1321429810	1121	G>W		No	ClinGen TOPMed
CA362942071 rs1402864939	1124	A>T		No	ClinGen gnomAD
rs1464151930 CA362942063	1125	T>A		No	ClinGen gnomAD
CA3685162 rs747298977	1126	Y>S		No	ClinGen ExAC TOPMed gnomAD
CA3685161 rs777957320	1129	M>V		No	ClinGen ExAC gnomAD
CA362942030 rs1478604842	1130	A>T		No	ClinGen gnomAD
CA362941990 rs1192957132	1135	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs772223532 CA3685160	1138	Q>R		No	ClinGen ExAC gnomAD
CA135885365 rs967224128	1139	K>E		No	ClinGen gnomAD
rs1258936935 CA362941962	1139	K>R		No	ClinGen gnomAD
TCGA novel	1141	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3685159 rs370862886	1141	E>K		No	ClinGen ESP ExAC gnomAD
CA362941913 rs1457458716	1146	R>G		No	ClinGen TOPMed
CA3685158 rs533040091	1146	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA3685156 rs755459471	1148	S>F		No	ClinGen ExAC TOPMed gnomAD
CA3685155 rs754344047	1151	C>F		No	ClinGen ExAC gnomAD
rs756546832 CA3685153	1152	Y>*		No	ClinGen ExAC gnomAD
rs780318572 CA3685154	1152	Y>C		No	ClinGen ExAC gnomAD
rs750162206 CA3685152	1153	D>N		No	ClinGen ExAC gnomAD
CA135885331 rs199878572	1154	M>T		No	ClinGen 1000Genomes TOPMed gnomAD
CA3685151 rs767294571	1155	F>S		No	ClinGen ExAC gnomAD
rs761493188 CA3685150	1156	H>N		No	ClinGen ExAC gnomAD
rs1331464317 CA362941843	1156	H>R		No	ClinGen TOPMed gnomAD
rs1397722950 CA362941813	1160	T>I		No	ClinGen gnomAD
CA3685148 rs555807076	1163	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1444577050 CA362941785	1164	E>D		No	ClinGen gnomAD
CA135885295 rs530512827	1165	V>I		No	ClinGen gnomAD
CA362941783 rs530512827	1165	V>L		No	ClinGen gnomAD
CA135885292 rs1041031049	1166	G>C		No	ClinGen TOPMed gnomAD
rs1423705875 CA362941738	1171	I>M		No	ClinGen gnomAD
rs1554168045 CA3685145	1171	I>V		No	ClinGen Ensembl
rs775467846 CA3685144	1172	A>G		No	ClinGen ExAC gnomAD
TCGA novel	1172	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs373444968 CA3685143	1173	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
COSM284798 CA3685142 rs759339292	1175	R>*	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA3685141 rs776339464	1175	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA135885280 rs942737928	1177	V>G		No	ClinGen TOPMed gnomAD
CA362941700 rs1309848477	1178	I>T		No	ClinGen gnomAD
TCGA novel	1184	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1185	L>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs748350026 CA362941647	1185	L>F		No	ClinGen ExAC TOPMed gnomAD
rs201848424 CA3685138	1186	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs768746835 CA3685137	1187	E>Q		No	ClinGen ExAC gnomAD
TCGA novel	1189	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1015141862 CA135885273	1190	E>*		No	ClinGen Ensembl
TCGA novel	1191	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1392361046 CA362941598	1192	Y>C		No	ClinGen gnomAD
CA3685135 rs780601128	1197	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs756634654 CA3685134 COSM1264912	1200	R>C	Variant assessed as Somatic; 0.0 impact. oesophagus [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs375814055 CA3685132	1200	R>H	Variant assessed as Somatic; 4.733e-05 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
COSM323205 rs375814055 CA3685133	1200	R>L	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs1268051518 CA362941536	1201	I>M		No	ClinGen TOPMed
CA362941538 rs1196185147	1201	I>T		No	ClinGen TOPMed
CA362941542 rs1481460885	1201	I>V		No	ClinGen TOPMed
rs868646271 CA135885251	1202	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA135885246 rs376185929	1204	L>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1437975122 CA362941514	1205	W>G		No	ClinGen gnomAD
TCGA novel	1210	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751202396 CA3685130	1211	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA3685129 rs145291497	1211	L>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1453559007 CA362941455	1213	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1581885156 CA362941442	1215	D>V		No	ClinGen Ensembl
rs757912563 CA3685128	1216	N>K		No	ClinGen ExAC TOPMed gnomAD
rs1286721691 CA362941403	1221	V>I		No	ClinGen gnomAD
CA362941396 rs1242219710	1222	T>A		No	ClinGen gnomAD
CA362941345 rs1336246576	1229	K>T		No	ClinGen TOPMed gnomAD
CA135885221 rs969732913	1231	A>V		No	ClinGen TOPMed
rs1300872917 CA362941327	1232	T>N		No	ClinGen gnomAD
rs766136394 CA3685122	1233	D>N		No	ClinGen ExAC TOPMed gnomAD
CA3685121 rs761977291 COSM314996	1233	D>V	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
TCGA novel	1236	L>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362941283 rs1339852131	1238	I>M		No	ClinGen TOPMed
rs147395811 CA3685118	1239	S>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs1297938345 CA362941270	1240	F>C		No	ClinGen TOPMed
rs1173263131 CA362941254	1242	N>S		No	ClinGen gnomAD
rs775648744 CA3685117	1243	T>K		No	ClinGen ExAC TOPMed gnomAD
rs770457386 CA3685116	1244	A>S		No	ClinGen ExAC TOPMed gnomAD
rs1290737587 CA362941242	1244	A>V		No	ClinGen TOPMed
CA135885163 rs776184651	1247	P>H		No	ClinGen Ensembl
CA362941220 rs1330935201	1248	S>*		No	ClinGen gnomAD
rs746329974 CA3685115	1249	F>L		No	ClinGen ExAC gnomAD
CA362941203 rs1357090299	1250	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	1253	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362941178 rs1224538691	1254	K>T		No	ClinGen TOPMed
rs1393372535 CA362941172	1255	N>D		No	ClinGen TOPMed gnomAD
CA362941168 rs1161797088	1255	N>I		No	ClinGen gnomAD
CA3685114 rs781724385	1255	N>K		No	ClinGen ExAC gnomAD
rs147907593 CA3685113	1256	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA135885134 rs977340930	1257	Y>C		No	ClinGen TOPMed
rs1218445832 CA362941158	1257	Y>H		No	ClinGen TOPMed gnomAD
TCGA novel	1261	A>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA135885132 rs867552316	1262	E>*		No	ClinGen Ensembl
CA3685112 rs189163480	1263	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA3685111 rs144540037	1264	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA3685110 rs757920531	1265	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA362941080 rs1581884700	1269	L>F		No	ClinGen Ensembl
TCGA novel	1269	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1222522631 CA362941069	1271	F>L		No	ClinGen gnomAD
CA3685108 rs764676290	1271	F>S		No	ClinGen ExAC TOPMed gnomAD
rs1429007456 CA362941060	1272	P>L		No	ClinGen gnomAD
CA3685102 rs764385294	1276	L>F		No	ClinGen ExAC gnomAD
CA3685103 rs764385294	1276	L>I		No	ClinGen ExAC gnomAD
rs1562028959 CA362941033	1277	C>R		No	ClinGen Ensembl
CA3685100 rs140560647 COSM2155203	1280	G>R	Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs769973774 CA3685099	1281	F>S		No	ClinGen ExAC TOPMed gnomAD
rs1195617649 CA362940997	1282	S>A		No	ClinGen gnomAD
CA3685098 rs760161942	1282	S>F		No	ClinGen ExAC gnomAD
CA362940989 rs1241497756	1283	T>I		No	ClinGen TOPMed gnomAD
TCGA novel	1283	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362940990 rs1241497756	1283	T>S		No	ClinGen TOPMed gnomAD
rs1222990785 CA362940985	1284	L>S		No	ClinGen Ensembl
rs1006917126 CA135885067	1285	S>N		No	ClinGen TOPMed
rs771284097 CA3685096	1291	H>D		No	ClinGen ExAC gnomAD
CA3685095 rs747403899	1291	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1318187581 CA362940930	1292	R>T		No	ClinGen gnomAD
CA362940915 rs1351632322	1294	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	1298	H>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362940884 rs1485947171	1298	H>R		No	ClinGen TOPMed
rs771777005 CA3685093	1299	Y>C		No	ClinGen ExAC gnomAD
CA135885064 rs373104733	1299	Y>H		No	ClinGen ESP gnomAD
CA3685092 rs747773591	1303	V>I		No	ClinGen ExAC gnomAD
CA3685090 rs754476328	1305	L>F		No	ClinGen ExAC gnomAD
rs143458888 CA3685089	1308	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs779983949 CA3685088	1310	P>L		No	ClinGen ExAC gnomAD
CA3685086 rs750266983	1313	D>E		No	ClinGen ExAC gnomAD
rs767170997 CA3685085	1319	K>*		No	ClinGen ExAC gnomAD
rs1562028722 CA362940747	1319	K>R		No	ClinGen Ensembl
CA362940735 rs1473746908	1321	A>T		No	ClinGen TOPMed gnomAD
rs1182484361 CA362940717	1323	L>*		No	ClinGen gnomAD
rs1241149417 CA362940720	1323	L>V		No	ClinGen gnomAD
rs1457801919 CA362940713	1324	S>P		No	ClinGen gnomAD
CA135885021 rs996388524	1325	H>R		No	ClinGen Ensembl

1 associated diseases with Q6R2W3

[MIM: 619401]: Lymphatic malformation 11 (LMPHM11)

A form of primary lymphedema, a disease characterized by swelling of body parts due to developmental anomalies and functional defects of the lymphatic system. Patients with lymphedema may suffer from recurrent local infections. LMPHM11 is an autosomal dominant form characterized by onset of lower extremity edema in the second or third decade of life. Some affected individuals may have subclinical lymphatic malformations. {ECO:0000269|PubMed:32947856}. Note=The disease may be caused by variants affecting the gene represented in this entry.

Without disease ID

A form of primary lymphedema, a disease characterized by swelling of body parts due to developmental anomalies and functional defects of the lymphatic system. Patients with lymphedema may suffer from recurrent local infections. LMPHM11 is an autosomal dominant form characterized by onset of lower extremity edema in the second or third decade of life. Some affected individuals may have subclinical lymphatic malformations. {ECO:0000269|PubMed:32947856}. Note=The disease may be caused by variants affecting the gene represented in this entry.

4 regional properties for Q6R2W3

Type	Name	Position	InterPro Accession
domain	Helicase, C-terminal	305 - 473	IPR001650
domain	DEAD/DEAH box helicase domain	116 - 280	IPR011545
domain	Helicase superfamily 1/2, ATP-binding domain	110 - 309	IPR014001
domain	RNA helicase, DEAD-box type, Q motif	91 - 119	IPR014014

Functions

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

2 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name	Definition
nucleic acid binding	Binding to a nucleic acid.

3 GO annotations of biological process

Name	Definition
DNA integration	The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
positive regulation of cell cycle	Any process that activates or increases the rate or extent of progression through the cell cycle.
positive regulation of epithelial cell proliferation	Any process that activates or increases the rate or extent of epithelial cell proliferation.

189 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
A4FUB7	GIN1	Gypsy retrotransposon integrase-like protein 1	Bos taurus (Bovine)	PR
Q08DS3	OSR1	Protein odd-skipped-related 1	Bos taurus (Bovine)	PR
Q2VWH6	FEZF2	Fez family zinc finger protein 2	Bos taurus (Bovine)	PR
A6QNZ0	ZSCAN26	Zinc finger and SCAN domain-containing protein 26	Bos taurus (Bovine)	PR
A7MBI1	ZFP69	Zinc finger protein 69 homolog	Bos taurus (Bovine)	PR
Q08705	CTCF	Transcriptional repressor CTCF	Gallus gallus (Chicken)	PR
O42409	GFI1B	Zinc finger protein Gfi-1b	Gallus gallus (Chicken)	PR
A2T6W2	ZNF449	Zinc finger protein 449	Pan troglodytes (Chimpanzee)	PR
Q9U405	grau	Transcription factor grauzone	Drosophila melanogaster (Fruit fly)	PR
Q7K0S9	sug	Zinc finger protein GLIS2 homolog	Drosophila melanogaster (Fruit fly)	PR
P20385	Cf2	Chorion transcription factor Cf2	Drosophila melanogaster (Fruit fly)	PR
Q86P48	ATbp	AT-rich binding protein	Drosophila melanogaster (Fruit fly)	PR
Q9P2P1	NYNRIN	Protein NYNRIN	Homo sapiens (Human)	PR
Q9UN19	DAPP1	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide	Homo sapiens (Human)	PR
P28698	MZF1	Myeloid zinc finger 1	Homo sapiens (Human)	PR
Q9NTW7	ZFP64	Zinc finger protein 64	Homo sapiens (Human)	PR
O14978	ZNF263	Zinc finger protein 263	Homo sapiens (Human)	PR
O60304	ZNF500	Zinc finger protein 500	Homo sapiens (Human)	PR
P08151	GLI1	Zinc finger protein GLI1	Homo sapiens (Human)	PR
Q9UFB7	ZBTB47	Zinc finger and BTB domain-containing protein 47	Homo sapiens (Human)	PR
P18146	EGR1	Early growth response protein 1	Homo sapiens (Human)	PR
Q9Y5W3	KLF2	Krueppel-like factor 2	Homo sapiens (Human)	PR
Q9UNY5	ZNF232	Zinc finger protein 232	Homo sapiens (Human)	PR
Q96SZ4	ZSCAN10	Zinc finger and SCAN domain-containing protein 10	Homo sapiens (Human)	PR
P17028	ZNF24	Zinc finger protein 24	Homo sapiens (Human)	PR
P57682	KLF3	Krueppel-like factor 3	Homo sapiens (Human)	PR
P25490	YY1	Transcriptional repressor protein YY1	Homo sapiens (Human)	SS
O43296	ZNF264	Zinc finger protein 264	Homo sapiens (Human)	PR
P49711	CTCF	Transcriptional repressor CTCF	Homo sapiens (Human)	PR
Q9NQX1	PRDM5	PR domain zinc finger protein 5	Homo sapiens (Human)	PR
Q9HBE1	PATZ1	POZ-, AT hook-, and zinc finger-containing protein 1	Homo sapiens (Human)	PR
Q8TAX0	OSR1	Protein odd-skipped-related 1	Homo sapiens (Human)	PR
Q9UL58	ZNF215	Zinc finger protein 215	Homo sapiens (Human)	PR
Q8TBJ5	FEZF2	Fez family zinc finger protein 2	Homo sapiens (Human)	PR
Q96SR6	ZNF382	Zinc finger protein 382	Homo sapiens (Human)	PR
Q96IT1	ZNF496	Zinc finger protein 496	Homo sapiens (Human)	PR
Q96N95	ZNF396	Zinc finger protein 396	Homo sapiens (Human)	PR
Q9ULJ3	ZBTB21	Zinc finger and BTB domain-containing protein 21	Homo sapiens (Human)	PR
O75840	KLF7	Krueppel-like factor 7	Homo sapiens (Human)	PR
Q9H9D4	ZNF408	Zinc finger protein 408	Homo sapiens (Human)	PR
Q13127	REST	RE1-silencing transcription factor	Homo sapiens (Human)	PR
Q8IZM8	ZNF654	Zinc finger protein 654	Homo sapiens (Human)	PR
Q14526	HIC1	Hypermethylated in cancer 1 protein	Homo sapiens (Human)	PR
P17022	ZNF18	Zinc finger protein 18	Homo sapiens (Human)	PR
Q86XF7	ZNF575	Zinc finger protein 575	Homo sapiens (Human)	PR
Q06889	EGR3	Early growth response protein 3	Homo sapiens (Human)	PR
Q8NAM6	ZSCAN4	Zinc finger and SCAN domain-containing protein 4	Homo sapiens (Human)	PR
Q08ER8	ZNF543	Zinc finger protein 543	Homo sapiens (Human)	PR
P17029	ZKSCAN1	Zinc finger protein with KRAB and SCAN domains 1	Homo sapiens (Human)	PR
Q8N680	ZBTB2	Zinc finger and BTB domain-containing protein 2	Homo sapiens (Human)	PR
O95625	ZBTB11	Zinc finger and BTB domain-containing protein 11	Homo sapiens (Human)	PR
Q9NPC7	MYNN	Myoneurin	Homo sapiens (Human)	PR
Q96BV0	ZNF775	Zinc finger protein 775	Homo sapiens (Human)	PR
Q8NF99	ZNF397	Zinc finger protein 397	Homo sapiens (Human)	PR
Q63HK3	ZKSCAN2	Zinc finger protein with KRAB and SCAN domains 2	Homo sapiens (Human)	PR
Q5FWF6	ZNF789	Zinc finger protein 789	Homo sapiens (Human)	PR
Q15776	ZKSCAN8	Zinc finger protein with KRAB and SCAN domains 8	Homo sapiens (Human)	PR
Q53GI3	ZNF394	Zinc finger protein 394	Homo sapiens (Human)	PR
O95125	ZNF202	Zinc finger protein 202	Homo sapiens (Human)	PR
Q05516	ZBTB16	Zinc finger and BTB domain-containing protein 16	Homo sapiens (Human)	PR
Q9H116	GZF1	GDNF-inducible zinc finger protein 1	Homo sapiens (Human)	PR
Q8N0Y2	ZNF444	Zinc finger protein 444	Homo sapiens (Human)	PR
Q6P9G9	ZNF449	Zinc finger protein 449	Homo sapiens (Human)	PR
Q8IW36	ZNF695	Zinc finger protein 695	Homo sapiens (Human)	PR
Q5VTD9	GFI1B	Zinc finger protein Gfi-1b	Homo sapiens (Human)	PR
Q6PG37	ZNF790	Zinc finger protein 790	Homo sapiens (Human)	PR
Q9NQV6	PRDM10	PR domain zinc finger protein 10	Homo sapiens (Human)	PR
Q9Y2D9	ZNF652	Zinc finger protein 652	Homo sapiens (Human)	PR
Q5TC79	ZBTB37	Zinc finger and BTB domain-containing protein 37	Homo sapiens (Human)	PR
Q9Y4E5	ZNF451	E3 SUMO-protein ligase ZNF451	Homo sapiens (Human)	PR
Q8ND82	ZNF280C	Zinc finger protein 280C	Homo sapiens (Human)	PR
Q49AA0	ZFP69	Zinc finger protein 69 homolog	Homo sapiens (Human)	PR
O43298	ZBTB43	Zinc finger and BTB domain-containing protein 43	Homo sapiens (Human)	PR
Q9Y330	ZBTB12	Zinc finger and BTB domain-containing protein 12	Homo sapiens (Human)	PR
Q13105	ZBTB17	Zinc finger and BTB domain-containing protein 17	Homo sapiens (Human)	PR
P51508	ZNF81	Zinc finger protein 81	Homo sapiens (Human)	PR
Q5JNZ3	ZNF311	Zinc finger protein 311	Homo sapiens (Human)	PR
Q9BRR0	ZKSCAN3	Zinc finger protein with KRAB and SCAN domains 3	Homo sapiens (Human)	PR
Q969J2	ZKSCAN4	Zinc finger protein with KRAB and SCAN domains 4	Homo sapiens (Human)	PR
P49910	ZNF165	Zinc finger protein 165	Homo sapiens (Human)	PR
Q9Y4X4	KLF12	Krueppel-like factor 12	Homo sapiens (Human)	PR
P10074	ZBTB48	Telomere zinc finger-associated protein	Homo sapiens (Human)	PR
P17010	ZFX	Zinc finger X-chromosomal protein	Homo sapiens (Human)	PR
Q9H5H4	ZNF768	Zinc finger protein 768	Homo sapiens (Human)	PR
Q6NSZ9	ZSCAN25	Zinc finger and SCAN domain-containing protein 25	Homo sapiens (Human)	PR
Q9Y2L8	ZKSCAN5	Zinc finger protein with KRAB and SCAN domains 5	Homo sapiens (Human)	PR
Q86UZ6	ZBTB46	Zinc finger and BTB domain-containing protein 46	Homo sapiens (Human)	PR
Q9NX65	ZSCAN32	Zinc finger and SCAN domain-containing protein 32	Homo sapiens (Human)	PR
O14771	ZNF213	Zinc finger protein 213	Homo sapiens (Human)	PR
Q8IWY8	ZSCAN29	Zinc finger and SCAN domain-containing protein 29	Homo sapiens (Human)	PR
Q8NCP5	ZBTB44	Zinc finger and BTB domain-containing protein 44	Homo sapiens (Human)	PR
P41182	BCL6	B-cell lymphoma 6 protein	Homo sapiens (Human)	PR
Q9NQX0	PRDM6	Putative histone-lysine N-methyltransferase PRDM6	Homo sapiens (Human)	PR
Q9BU19	ZNF692	Zinc finger protein 692	Homo sapiens (Human)	PR
Q08AG5	ZNF844	Zinc finger protein 844	Homo sapiens (Human)	PR
P98182	ZNF200	Zinc finger protein 200	Homo sapiens (Human)	PR
Q9UK11	ZNF223	Zinc finger protein 223	Homo sapiens (Human)	PR
O15156	ZBTB7B	Zinc finger and BTB domain-containing protein 7B	Homo sapiens (Human)	PR
Q6ZMS7	ZNF783	Zinc finger protein 783	Homo sapiens (Human)	PR
P59923	ZNF445	Zinc finger protein 445	Homo sapiens (Human)	PR
Q8N859	ZNF713	Zinc finger protein 713	Homo sapiens (Human)	PR
Q99612	KLF6	Krueppel-like factor 6	Homo sapiens (Human)	PR
Q8TD17	ZNF398	Zinc finger protein 398	Homo sapiens (Human)	PR
P52739	ZNF131	Zinc finger protein 131	Homo sapiens (Human)	PR
A6NGD5	ZSCAN5C	Zinc finger and SCAN domain-containing protein 5C	Homo sapiens (Human)	PR
Q05215	EGR4	Early growth response protein 4	Homo sapiens (Human)	PR
Q7Z398	ZNF550	Zinc finger protein 550	Homo sapiens (Human)	PR
Q9Y2K1	ZBTB1	Zinc finger and BTB domain-containing protein 1	Homo sapiens (Human)	PR
Q96N20	ZNF75A	Zinc finger protein 75A	Homo sapiens (Human)	PR
A6NJL1	ZSCAN5B	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	PR
A1YPR0	ZBTB7C	Zinc finger and BTB domain-containing protein 7C	Homo sapiens (Human)	PR
Q9NWS9	ZNF446	Zinc finger protein 446	Homo sapiens (Human)	PR
P24278	ZBTB25	Zinc finger and BTB domain-containing protein 25	Homo sapiens (Human)	PR
Q96N38	ZNF714	Zinc finger protein 714	Homo sapiens (Human)	PR
Q86YH2	ZNF280B	Zinc finger protein 280B	Homo sapiens (Human)	PR
Q6ZNG9	KRBA2	KRAB-A domain-containing protein 2	Homo sapiens (Human)	PR
P0CF97	FAM200B	Protein FAM200B	Homo sapiens (Human)	PR
Q9QXT1	Dapp1	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide	Mus musculus (Mouse)	PR
O08584	Klf6	Krueppel-like factor 6	Mus musculus (Mouse)	PR
Q61164	Ctcf	Transcriptional repressor CTCF	Mus musculus (Mouse)	PR
Q810A1	Znf18	Zinc finger protein 18	Mus musculus (Mouse)	PR
Q8BGS3	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Mus musculus (Mouse)	PR
Q00899	Yy1	Transcriptional repressor protein YY1	Mus musculus (Mouse)	PR
P41183	Bcl6	B-cell lymphoma 6 protein homolog	Mus musculus (Mouse)	PR
Q9DAI4	Zbtb43	Zinc finger and BTB domain-containing protein 43	Mus musculus (Mouse)	PR
O70237	Gfi1b	Zinc finger protein Gfi-1b	Mus musculus (Mouse)	PR
Q99KZ6	Znf639	Zinc finger protein 639	Mus musculus (Mouse)	PR
Q9Z1D9	Znf394	Zinc finger protein 394	Mus musculus (Mouse)	PR
Q9CXE0	Prdm5	PR domain zinc finger protein 5	Mus musculus (Mouse)	PR
P43300	Egr3	Early growth response protein 3	Mus musculus (Mouse)	PR
Q9DAU9	Znf654	Zinc finger protein 654	Mus musculus (Mouse)	PR
Q9R1Y5	Hic1	Hypermethylated in cancer 1 protein	Mus musculus (Mouse)	PR
Q8R0T2	Znf768	Zinc finger protein 768	Mus musculus (Mouse)	PR
Q9WVG7	Osr1	Protein odd-skipped-related 1	Mus musculus (Mouse)	PR
Q8BI73	Znf775	Zinc finger protein 775	Mus musculus (Mouse)	PR
Q8VCZ7	Zbtb7c	Zinc finger and BTB domain-containing protein 7C	Mus musculus (Mouse)	PR
Q91VN1	Znf24	Zinc finger protein 24	Mus musculus (Mouse)	PR
Q9DB38	Znf580	Zinc finger protein 580	Mus musculus (Mouse)	PR
A7KBS4	Zscan4d	Zinc finger and SCAN domain containing protein 4D	Mus musculus (Mouse)	PR
Q91VW9	Zkscan3	Zinc finger protein with KRAB and SCAN domains 3	Mus musculus (Mouse)	PR
P10925	Zfy1	Zinc finger Y-chromosomal protein 1	Mus musculus (Mouse)	PR
P08046	Egr1	Early growth response protein 1	Mus musculus (Mouse)	PR
Q3TTC2	Yy2	Transcription factor YY2	Mus musculus (Mouse)	PR
Q3UTQ7	Prdm10	PR domain zinc finger protein 10	Mus musculus (Mouse)	PR
Q6P3Y5	Znf280c	Zinc finger protein 280C	Mus musculus (Mouse)	PR
Q9ERU3	Znf22	Zinc finger protein 22	Mus musculus (Mouse)	PR
Q8VIG1	Rest	RE1-silencing transcription factor	Mus musculus (Mouse)	PR
Q9Z1D8	Zkscan5	Zinc finger protein with KRAB and SCAN domains 5	Mus musculus (Mouse)	PR
Q8BID6	Zbtb46	Zinc finger and BTB domain-containing protein 46	Mus musculus (Mouse)	PR
P17012	Zfx	Zinc finger X-chromosomal protein	Mus musculus (Mouse)	PR
Q9WUK6	Zbtb18	Zinc finger and BTB domain-containing protein 18	Mus musculus (Mouse)	PR
O35738	Klf12	Krueppel-like factor 12	Mus musculus (Mouse)	PR
B2RXC5	Znf382	Zinc finger protein 382	Mus musculus (Mouse)	PR
O08900	Ikzf3	Zinc finger protein Aiolos	Mus musculus (Mouse)	PR
Q5DU09	Znf652	Zinc finger protein 652	Mus musculus (Mouse)	PR
Q5RJ54	Zscan26	Zinc finger and SCAN domain-containing protein 26	Mus musculus (Mouse)	PR
Q8BLM0	Klf8	Krueppel-like factor 8	Mus musculus (Mouse)	PR
Q99JB0	Klf7	Krueppel-like factor 7	Mus musculus (Mouse)	PR
Q8R0A2	Zbtb44	Zinc finger and BTB domain-containing protein 44	Mus musculus (Mouse)	PR
P20662	Zfy2	Zinc finger Y-chromosomal protein 2	Mus musculus (Mouse)	PR
Q80VJ6	Zscan4c	Zinc finger and SCAN domain containing protein 4C	Mus musculus (Mouse)	PR
Q3URS2	Zscan4f	Zinc finger and SCAN domain containing protein 4F	Mus musculus (Mouse)	PR
Q60980	Klf3	Krueppel-like factor 3	Mus musculus (Mouse)	PR
Q8K3J5	Znf131	Zinc finger protein 131	Mus musculus (Mouse)	PR
Q9Z2K3	Znf394	Zinc finger protein 394	Rattus norvegicus (Rat)	PR
Q642B9	Znf18	Zinc finger protein 18	Rattus norvegicus (Rat)	PR
B0K011	Osr1	Protein odd-skipped-related 1	Rattus norvegicus (Rat)	PR
D3ZUU2	Gzf1	GDNF-inducible zinc finger protein 1	Rattus norvegicus (Rat)	PR
B1WBU4	Zbtb8a	Zinc finger and BTB domain-containing protein 8A	Rattus norvegicus (Rat)	PR
Q7TNK3	Znf24	Zinc finger protein 24	Rattus norvegicus (Rat)	PR
O35819	Klf6	Krueppel-like factor 6	Rattus norvegicus (Rat)	PR
Q9R1D1	Ctcf	Transcriptional repressor CTCF	Rattus norvegicus (Rat)	PR
P43301	Egr3	Early growth response protein 3	Rattus norvegicus (Rat)	PR
P08154	Egr1	Early growth response protein 1	Rattus norvegicus (Rat)	PR
A0JPL0	Znf382	Zinc finger protein 382	Rattus norvegicus (Rat)	PR
Q4KLI1	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Rattus norvegicus (Rat)	PR
A1L1J6	Znf652	Zinc finger protein 652	Rattus norvegicus (Rat)	PR
Q94KB1	MLO14	MLO-like protein 14	Arabidopsis thaliana (Mouse-ear cress)	PR
O80580	MLO15	MLO-like protein 15	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SMP1	XTH11	Probable xyloglucan endotransglucosylase/hydrolase protein 11	Arabidopsis thaliana (Mouse-ear cress)	PR
O49621	MLO1	MLO-like protein 1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FK75	At5g45670	GDSL esterase/lipase At5g45670	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FI00	MLO11	MLO-like protein 11	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SHD0	ZAT4	Zinc finger protein ZAT4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q0P4X6	zbtb44	Zinc finger and BTB domain-containing protein 44	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
A4II20	egr1	Early growth response protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q6P882	zbtb8a.2	Zinc finger and BTB domain-containing protein 8A.2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q567C6	znf367	Zinc finger protein 367	Danio rerio (Zebrafish) (Brachydanio rerio)	PR
A7Y7X5	znf711	Zinc finger protein 711	Danio rerio (Zebrafish) (Brachydanio rerio)	PR

10	20	30	40	50	60
MEAVSRVFPA	LAGQAPEEQG	EIIKVKVKEE	DHTWDQESAL	RRNLSYTREL	SRQRFRQFCY
70	80	90	100	110	120
QETPGPREAL	SQLRELCRQW	LNPEIHTKEQ	ILELLVLEQF	LTILPEELQS	WVREHNPESG
130	140	150	160	170	180
EEVVTLLEDL	ERELDEPRQQ	VSQGTYGQEV	SMEEMIPLDS	AKESLGTQLQ	SMEDRMECES
190	200	210	220	230	240
PEPHPLQDNG	SFLWFSMMSQ	SMGGDNLSSL	DTNEAEIEPE	NMREKFFRSL	ARLLENKSNN
250	260	270	280	290	300
TKIFSKAKYC	QLIKEVKEAK	AKAKKESVDY	RRLARFDVIL	VQGNEKLIEA	VNGETDKIRY
310	320	330	340	350	360
YLHSEDLFDI	LHNTHLSIGH	GGRTRMEKEL	QAKYKNITKE	VIMLYLTLCK	PCQQKNSKLK
370	380	390	400	410	420
KVLTSKSIKE	VSSRCQVDLI	DMQLNPDGEY	RFILHYQDLC	TKLTFLRSLK	SKRPTEVAHA
430	440	450	460	470	480
LLDIFTIIGA	PSVLQSDNGR	EFSSQVVSEL	SNIWPELKIV	HGKSQTCQSQ	SSAEQTEDIR
490	500	510	520	530	540
KRIFSWMQTN	NSSHWTEFLW	FIQMSQNQPY	HRSMQQTPCE	SAFSSEAKLG	LSHSQLTEEL
550	560	570	580	590	600
VASLHTENEL	DQADKELENT	LRAQYEENIE	TGTDSSDIEE	NLSVTPKVAE	KSPPESRLRF
610	620	630	640	650	660
LSCVVCEKEC	TGVNSCISCD	GNIHAICGVP	SQHGTEGCGR	QITCSLCYET	STMKRKHDEI
670	680	690	700	710	720
QRSLPVKPSK	MLKPSGTPFS	PDKVGDWMAK	QASLDFFVKK	RHAFSEHSSS	NKRNVNNRSY
730	740	750	760	770	780
PEEGKTKRVH	ASFTRKYDPS	YIEFGFVAVI	DGEVLKPQCI	ICGDVLANEA	MKPSKLKRHL
790	800	810	820	830	840
YSKHKEISSQ	PKEFFERKSS	ELKSQPKQVF	NVSHINISAL	RASYKVALPV	AKSKTPYTIA
850	860	870	880	890	900
ETLVKDCIKE	VCLEMLGESA	AKKVAQVPLS	NDTIARRIQE	LANDMEDQLI	EQIKLAKYFS
910	920	930	940	950	960
LQLDECRDIA	NMIILLVYVR	FEHDDDIKEE	FFFSASLPTN	TTSSELYEAV	KNYIVNKCGL
970	980	990	1000	1010	1020
EFKFCVGVCS	DGAASMTGKH	SEVVTQIKEL	APECKTTHCF	IHRESLAMKK	ISAELNSVLN
1030	1040	1050	1060	1070	1080
DIVKIVNYIK	SNSLNSRLFS	LLCDNMEADH	KQLLLHAEIR	WLSRGKVLSR	MFEIRNELLV
1090	1100	1110	1120	1130	1140
FLQGKKPMWS	QLFKDVNWTA	RLAYLSDIFS	IFNDLNASMQ	GKNATYFSMA	DKVEGQKQKL
1150	1160	1170	1180	1190	1200
EAWKNRISTD	CYDMFHNLTT	IINEVGNDLD	IAHLRKVISE	HLTNLLECFE	FYFPSKEDPR
1210	1220	1230	1240	1250	1260
IGNLWIQNPF	LSSKDNLNLT	VTLQDKLLKL	ATDEGLKISF	ENTASLPSFW	IKAKNDYPEL
1270	1280	1290	1300	1310	1320
AEIALKLLLL	FPSTYLCETG	FSTLSVIKTK	HRNSLNIHYP	LRVALSSIQP	RLDKLTSKKQ

AHLSH