Q6L5D4
Gene name |
MPK9 (Os05g0582400, LOC_Os05g50560, OJ1651_G11.11, OSJNBb0035N21.16) |
Protein name |
Mitogen-activated protein kinase 9 |
Names |
MAP kinase 9 |
Species |
Oryza sativa subsp japonica (Rice) |
KEGG Pathway |
|
EC number |
2.7.11.24: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
250-276 (Activation loop from InterPro)
Target domain |
107-398 (Protein kinase domain) |
Relief mechanism |
|
Assay |
|
Autoinhibited structure
Activated structure
1 structures for Q6L5D4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6L5D4-F1 | Predicted | AlphaFoldDB |
No variants for Q6L5D4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6L5D4 | |||||
No associated diseases with Q6L5D4
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.24 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| MAP kinase activity | Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular signal transduction | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. |
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
28 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P41808 | SMK1 | Sporulation-specific mitogen-activated protein kinase SMK1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q00772 | SLT2 | Mitogen-activated protein kinase SLT2/MPK1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| A5PKJ4 | MAPK7 | Mitogen-activated protein kinase 7 | Bos taurus (Bovine) | SS |
| Q9UBE8 | NLK | Serine/threonine-protein kinase NLK | Homo sapiens (Human) | SS |
| Q13164 | MAPK7 | Mitogen-activated protein kinase 7 | Homo sapiens (Human) | SS |
| Q9WVS8 | Mapk7 | Mitogen-activated protein kinase 7 | Mus musculus (Mouse) | SS |
| P0C865 | Mapk7 | Mitogen-activated protein kinase 7 | Rattus norvegicus (Rat) | SS |
| Q5J4W4 | MPK2 | Mitogen-activated protein kinase 2 | Oryza sativa subsp. japonica (Rice) | SS |
| Q336X9 | MPK6 | Mitogen-activated protein kinase 6 | Oryza sativa subsp. japonica (Rice) | SS |
| Q6L5F7 | MPK17 | Mitogen-activated protein kinase 17 | Oryza sativa subsp. japonica (Rice) | SS |
| Q5VP69 | MPK16 | Mitogen-activated protein kinase 16 | Oryza sativa subsp. japonica (Rice) | SS |
| Q0E459 | MPK13 | Mitogen-activated protein kinase 13 | Oryza sativa subsp. japonica (Rice) | SS |
| Q5Z9J0 | MPK12 | Mitogen-activated protein kinase 12 | Oryza sativa subsp. japonica (Rice) | SS |
| Q75KK8 | MPK14 | Mitogen-activated protein kinase 14 | Oryza sativa subsp. japonica (Rice) | SS |
| Q53N72 | MPK15 | Mitogen-activated protein kinase 15 | Oryza sativa subsp. japonica (Rice) | SS |
| Q5SN53 | MPK8 | Mitogen-activated protein kinase 8 | Oryza sativa subsp. japonica (Rice) | SS |
| Q67C40 | MPK7 | Mitogen-activated protein kinase 7 | Oryza sativa subsp. japonica (Rice) | SS |
| Q5VN19 | MPK11 | Mitogen-activated protein kinase 11 | Oryza sativa subsp. japonica (Rice) | SS |
| Q5ZCI1 | MPK10 | Mitogen-activated protein kinase 10 | Oryza sativa subsp. japonica (Rice) | SS |
| Q6Z437 | MPK3 | Mitogen-activated protein kinase 3 | Oryza sativa subsp. japonica (Rice) | SS |
| Q5Z859 | MPK4 | Mitogen-activated protein kinase 4 | Oryza sativa subsp. japonica (Rice) | SS |
| Q84UI5 | MPK1 | Mitogen-activated protein kinase 1 | Oryza sativa subsp. japonica (Rice) | SS |
| Q10N20 | MPK5 | Mitogen-activated protein kinase 5 | Oryza sativa subsp. japonica (Rice) | SS |
| O44514 | pmk-3 | Mitogen-activated protein kinase pmk-3 | Caenorhabditis elegans | PR |
| G5EBT1 | sma-5 | Mitogen-activated protein kinase sma-5 | Caenorhabditis elegans | SS |
| Q9SJG9 | MPK20 | Mitogen-activated protein kinase 20 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9C5C0 | MPK18 | Mitogen-activated protein kinase 18 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9LUC3 | MPK19 | Mitogen-activated protein kinase 19 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVKMRIGRR | RAIQQGIAEG | GFEWRRVWGC | READSRGALW | ELVWGERSVR | ERNAAGAAEE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VIALFIMDEM | CDPASNLEYV | VEKAKCDVHR | TSSAEEFFTE | YGDANRYRIQ | EVIGKGSYGV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VCSAIDLHTR | QKVAIKKVHN | IFEHVSDAAR | ILREIKLLRL | LRHPDIVEIK | HIMLPPSRRD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FKDIYVVFEL | MESDLHQVIK | ANDDLTKEHY | QFFLYQLLRA | LKYIHTASVY | HRDLKPKNIL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANSNCKLKIC | DFGLARVAFN | DTPTTVFWTD | YVATRWYRAP | ELCGSFFSKY | TPAIDIWSIG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CIFAEVLTGK | PLFPGKNVVH | QLDLMTDLLG | TPSMDTISRV | RNEKARRYLS | SMRKKDPVPF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SQKFPNADPL | ALKLLQRLLA | FDPKDRPTAE | EALTDPYFKG | LSKIDREPSC | QPIRKLEFEF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EQKKLSKEDI | RELIFQEILE | YHPQLQKNYR | NGRERATFLY | PSAVDQFKKQ | FSNLEESNGS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GSAIPMERKH | ASLPRSTTVH | STPIPPKEQP | LAASLKSSRP | VSDEPCKNPW | VMGGFSGNIP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TSSQVSQVAK | PVAPGRPVGS | VFPYETGSTN | DPYGPRGPVM | SSGYPPQQQI | SQAYGYHQVP |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ARMNCVEQSQ | AMDAYKMHSQ | SQTQAYAYPN | SKVTADVALD | MRGSTFHHSA | GSKNGSLDRM |
| 670 | 680 | 690 | |||
| VTQTDIYTRS | LNGIVAAATS | AGVGTNRKVG | AVPISTSRMY |