Q6JIY5

PR
Gene name
hoxc13a
Protein name
Homeobox protein Hox-C13a
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:58059
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

32-306 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6JIY5

Entry ID Method Resolution Chain Position Source
AF-Q6JIY5-F1 Predicted AlphaFoldDB

No variants for Q6JIY5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6JIY5

No associated diseases with Q6JIY5

3 regional properties for Q6JIY5

Type Name Position InterPro Accession
domain Homeobox domain 234 - 298 IPR001356
conserved_site Homeobox, conserved site 269 - 292 IPR017970
domain Homeobox protein Hox1A3 N-terminal 32 - 144 IPR022067

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

2 GO annotations of biological process

Name Definition
fin regeneration The regrowth of fin tissue following its loss or destruction.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P35452 HOXD12 Homeobox protein Hox-D12 Homo sapiens (Human) PR
P23812 Hoxd12 Homeobox protein Hox-D12 Mus musculus (Mouse) PR
Q9DDU0 hoxa11a Homeobox protein Hox-A11a Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MTTSQVLHPR WADTLMYVYE KSPNENNQNK SQIMEGLSGN CPATHCRELI SHPALGRHSG
70 80 90 100 110 120
TIATHQGSVY SDISSPETGR QCPAPQTSSS ASLSYGYPFG NPYYGCRLSH SHNVNLQQKP
130 140 150 160 170 180
CSYHPAEKYA ETSSALPTEE LSSRAKEFAF YPSLASSYQA VPGYLDMSVV PSISVHPEPR
190 200 210 220 230 240
HDALIPMEGY QHWALSNGWD GQVYCSKEQT QSSHLWKSPF PDVVPLQPEV SSYRRGRKKR
250 260 270 280 290 300
VPYTKIQLKE LEKEYAASKF ITKDKRRRIS ATTNLSERQV TIWFQNRRVK EKKFVSKSKT
NNHMHT