Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6AXQ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6AXQ7-F1 | Predicted | AlphaFoldDB |
No variants for Q6AXQ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6AXQ7 | |||||
No associated diseases with Q6AXQ7
3 regional properties for Q6AXQ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | 14-3-3 protein, conserved site | 43 - 53 | IPR023409-1 |
| conserved_site | 14-3-3 protein, conserved site | 216 - 235 | IPR023409-2 |
| domain | 14-3-3 domain | 5 - 247 | IPR023410 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VQN8 | CG3326 | Fidgetin-like protein 1 | Drosophila melanogaster (Fruit fly) | PR |
| Q6PIW4 | FIGNL1 | Fidgetin-like protein 1 | Homo sapiens (Human) | PR |
| Q9UBP0 | SPAST | Spastin | Homo sapiens (Human) | PR |
| A6NCM1 | IQCA1L | IQ and AAA domain-containing protein 1-like | Homo sapiens (Human) | PR |
| A6H690 | Iqca1l | IQ and AAA domain-containing protein 1-like | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEGTYQRLW | EASHATLEEV | LEKEPSPLEP | VLTRERQSFQ | YRISVLYLYY | LGLLRRFNLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YDQMVQPQKR | RLLRRLLDGV | AGRVLELKDE | LVRVDLCETH | CLDRVLQELK | LTPVDLEVPI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PKYFQLEQTS | TMKARQQMLA | EILARLEPLA | SQENLRGMSR | TEALIIVQCA | ERARQGRLRA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TFMREIRKEE | ERDRRIRENG | RQKFSQDQGA | IVIQKVWKGY | LQRKRIEQDR | RMEMEFIGML |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PSSSQTTRQN | ALAQAFVGEE | SRRTRQVEKE | EEFQEAIAKT | HESLTETEGP | DMKERMKDQI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RQWFIECHAL | TGRFPDYPDE | ASGGSYLIFA | DKTPEQVRQE | LEAQAQENKK | KEQEKNKDKV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KEKKEKKKKK | TKEEKAKKDP | EVMFKVLPSK | SIPVINAGHE | EFTSIWKSRY | DNKHPSQSFD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SETLREEKRK | QVEMEIRVQV | DELMRQELRN | LRLAVDREET | RPLKSPKKKG | GKKSGKKKKE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KDLTPDRSVD | SLFEELVVIG | LIKKSLLVTL | NDYIGDCLYL | GSTLTLANKI | PMPSLFDIRQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NIALYGVLRL | GSHDIHTMAP | LVRSILLVGP | SGMGKKMLVQ | AVCTETGANL | FDLSPGNVMG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KYPGKNGSQL | LMHIVFKVAR | VFQPSVIWIG | NTEKTFYKKI | PKEERRMDPK | RIKKDLMRAT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RQLGPGDRVM | LIGTTERPQL | AEMKGLCRFY | ERILFIPRPD | YASRYVLWKR | MIENQGIGVQ |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QTQSLDISAL | ARVSDGYTPG | HILQSIQSVL | TERRLLQLTK | KPLVASEFVV | HLAKLDPVYR |
| 790 | 800 | 810 | 820 | ||
| EEEESLKEWF | YKTPLGKKNI | KFTKDQQEAE | EARLAKEKKK | KK |