| anatomical structure morphogenesis |
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. |
| angiogenesis |
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. |
| apoptotic process involved in outflow tract morphogenesis |
Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. |
| artery morphogenesis |
The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. |
| blood vessel development |
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. |
| blood vessel diameter maintenance |
Any process that modulates the diameter of blood vessels. |
| blood vessel remodeling |
The reorganization or renovation of existing blood vessels. |
| brain development |
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
| camera-type eye development |
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. |
| cardiac muscle cell proliferation |
The expansion of a cardiac muscle cell population by cell division. |
| cell differentiation |
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| cell migration |
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. |
| cell population proliferation |
The multiplication or reproduction of cells, resulting in the expansion of a cell population. |
| cellular response to chemokine |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus. |
| cellular response to epidermal growth factor stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. |
| cerebellum development |
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. |
| chemokine-mediated signaling pathway |
The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| collagen fibril organization |
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. |
| embryonic heart tube development |
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. |
| endochondral ossification |
Replacement ossification wherein bone tissue replaces cartilage. |
| eye development |
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. |
| germ cell migration |
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. |
| glomerular epithelium development |
The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. |
| glycosaminoglycan metabolic process |
The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. |
| heart development |
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
| heart morphogenesis |
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
| in utero embryonic development |
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. |
| kidney development |
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. |
| lacrimal gland development |
The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. |
| lymph vessel development |
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. |
| maintenance of lens transparency |
A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina. |
| mesenchymal cell development |
The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. |
| mesenchymal cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. |
| negative regulation of angiogenesis |
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. |
| negative regulation of apoptotic process involved in outflow tract morphogenesis |
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. |
| negative regulation of lymphangiogenesis |
Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. |
| negative regulation of mitotic cell cycle |
Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. |
| negative regulation of transcription by RNA polymerase II |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| neural crest cell development |
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. |
| Notch signaling pathway |
The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| odontogenesis of dentin-containing tooth |
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. |
| ossification |
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. |
| ovarian follicle development |
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. |
| paraxial mesoderm formation |
The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. |
| positive regulation of core promoter binding |
Any process that activates or increases the frequency, rate or extent of core promoter binding. |
| positive regulation of DNA binding |
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). |
| positive regulation of DNA-templated transcription |
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| positive regulation of epithelial to mesenchymal transition |
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. |
| positive regulation of gene expression |
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| positive regulation of hematopoietic progenitor cell differentiation |
Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. |
| positive regulation of hematopoietic stem cell differentiation |
Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. |
| positive regulation of keratinocyte differentiation |
Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. |
| positive regulation of transcription by RNA polymerase II |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of DNA-templated transcription |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of organ growth |
Any process that modulates the frequency, rate or extent of growth of an organ of an organism. |
| regulation of transcription by RNA polymerase II |
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| skeletal system development |
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). |
| somitogenesis |
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. |
| ureteric bud development |
The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. |
| vascular endothelial growth factor receptor signaling pathway |
The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| vascular endothelial growth factor signaling pathway |
The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| ventricular cardiac muscle tissue morphogenesis |
The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. |
