Q5VTD9
PR
Gene name |
GFI1B |
Protein name |
Zinc finger protein Gfi-1b |
Names |
Growth factor independent protein 1B, Potential regulator of CDKN1A translocated in CML |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:8328 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5VTD9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5VTD9-F1 | Predicted | AlphaFoldDB |
309 variants for Q5VTD9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA5301949 rs527297896 RCV002264884 |
168 | C>F | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
rs144046935 RCV000477857 CA5301997 |
190 | R>W | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
CA5302001 rs753406078 RCV000852161 RCV001816827 RCV002245659 |
194 | C>Y | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP |
|
RCV000710041 rs1564180346 |
242 | H>missing | Storage pool disease of platelets [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV000622939 CA375380703 COSM1106337 rs1554724691 |
262 | D>N | Variant assessed as Somatic; impact. endometrium Inborn genetic diseases [NCI-TCGA, Cosmic, ClinVar] | Yes |
ClinGen cosmic curated ClinVar Ensembl NCI-TCGA dbSNP |
|
RCV000505272 rs1554724694 CA375380771 |
265 | K>* | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
rs587777211 RCV000088664 CA150742 |
287 | Q>* | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV000074460 rs397989794 RCV000088665 |
294 | H>missing | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinVar dbSNP |
|
rs775963992 CA5302127 RCV000505268 |
308 | L>P | Platelet-type bleeding disorder 17 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA375377437 rs1166024852 |
2 | P>T | No |
ClinGen gnomAD |
|
|
rs1472210411 CA375377448 |
3 | R>C | No |
ClinGen TOPMed |
|
|
CA5301791 rs528249677 |
9 | S>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 10 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1431101028 CA375377557 |
12 | A>T | No |
ClinGen gnomAD |
|
|
rs1009956222 CA200898259 |
13 | H>Y | No |
ClinGen TOPMed |
|
|
rs1564177115 CA375377575 |
14 | T>I | No |
ClinGen Ensembl |
|
|
CA375377572 COSM3721923 rs1481886997 |
14 | T>S | upper_aerodigestive_tract [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA200898265 rs1021775815 |
16 | H>Q | No |
ClinGen Ensembl |
|
|
rs1361526628 CA375377604 |
18 | P>L | No |
ClinGen gnomAD |
|
|
rs1292353837 CA375377601 |
18 | P>S | No |
ClinGen gnomAD |
|
|
rs753257069 CA5301796 |
19 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs143455917 CA5301797 |
19 | R>H | No |
ClinGen ESP ExAC gnomAD |
|
|
rs776935786 CA5301798 |
22 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA375377634 rs1370237253 |
23 | D>G | No |
ClinGen TOPMed |
|
|
CA5301799 RCV000934964 rs544599977 |
23 | D>N | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA5301800 rs556644999 |
24 | E>* | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA5301801 rs775541235 |
24 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA375377637 rs556644999 |
24 | E>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs764276098 CA5301803 |
25 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA5301804 rs764276098 |
25 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
rs938560000 CA200898292 |
25 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA200898296 rs1143162 |
29 | P>H | No |
ClinGen ExAC gnomAD |
|
|
CA5301808 rs1143162 |
29 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA375377669 rs1402824889 |
29 | P>S | No |
ClinGen gnomAD |
|
|
rs778609270 CA5301809 |
31 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1446582350 CA375377687 |
32 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1446582350 CA375377685 |
32 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
CA375377684 rs1564177246 |
32 | T>P | No |
ClinGen Ensembl |
|
|
rs1446582350 CA375377686 |
32 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA375377682 rs1564177246 |
32 | T>S | No |
ClinGen Ensembl |
|
|
CA5301811 rs568826386 |
33 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 33 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
RCV000968653 CA5301814 rs114955344 |
34 | V>M | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA375377711 rs1344576755 |
35 | P>H | No |
ClinGen gnomAD |
|
|
CA375377709 rs1588438405 |
35 | P>S | No |
ClinGen Ensembl |
|
|
rs975575009 CA200898499 |
36 | R>G | No |
ClinGen gnomAD |
|
|
CA375377740 rs1316317138 |
39 | A>G | No |
ClinGen gnomAD |
|
|
CA5301840 rs377661083 |
40 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1588438461 CA375377771 |
44 | P>T | No |
ClinGen Ensembl |
|
|
rs776592642 CA5301843 |
46 | L>R | No |
ClinGen ExAC gnomAD |
|
|
rs1443015063 CA375377791 |
47 | S>N | No |
ClinGen TOPMed |
|
|
rs370708708 CA5301845 |
47 | S>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1202082073 CA375377797 |
48 | T>S | No |
ClinGen gnomAD |
|
|
CA200898522 rs947590696 |
49 | L>V | No |
ClinGen Ensembl |
|
|
rs139685732 CA5301847 |
50 | F>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA375377820 rs1373207619 |
52 | N>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 55 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs545885234 CA5301849 |
56 | D>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs934326404 CA200898534 |
57 | W>C | No |
ClinGen Ensembl |
|
|
rs1364914633 CA375377855 |
57 | W>R | No |
ClinGen gnomAD |
|
|
CA5301851 rs202104252 |
58 | T>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs202104252 CA375377865 |
58 | T>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 59 | N>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5301854 rs149810016 |
60 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5301853 rs149810016 RCV000931356 |
60 | L>I | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA375377877 rs1381935874 |
60 | L>P | No |
ClinGen gnomAD |
|
|
rs1296372718 CA375377888 |
62 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA5301855 rs749864797 |
62 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs755483011 CA5301856 |
64 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755483011 CA375377903 |
64 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375377909 rs1360853713 |
65 | E>G | No |
ClinGen gnomAD |
|
|
rs373691272 CA5301859 |
67 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs748212888 CA5301858 |
67 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778075619 CA5301860 |
70 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA5301861 rs745670907 |
72 | L>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5301862 rs769769380 |
73 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA375378150 rs1429729062 |
74 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1429729062 CA375378149 |
74 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA5301863 rs775420059 |
75 | M>L | No |
ClinGen ExAC gnomAD |
|
|
CA375378167 rs1384514886 |
75 | M>R | No |
ClinGen gnomAD |
|
|
rs368601873 CA5301864 |
77 | P>L | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 78 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA200898572 rs1022720842 |
80 | E>K | No |
ClinGen gnomAD |
|
|
rs115534814 CA5301888 RCV000889665 |
81 | G>V | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs760373604 CA5301890 |
82 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs760373604 CA200898836 |
82 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765677480 CA5301894 |
86 | S>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375378315 rs1220919198 |
87 | R>* | No |
ClinGen gnomAD |
|
|
CA375378316 rs200908551 |
87 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5301895 rs200908551 |
87 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA375378322 rs1263195120 |
88 | P>R | No |
ClinGen gnomAD |
|
|
rs767778204 CA200898847 |
91 | G>E | No |
ClinGen Ensembl |
|
|
COSM1737092 rs565772612 CA5301896 |
91 | G>R | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
rs1470967398 CA375378356 |
93 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
CA5301900 rs781432577 |
96 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5301903 rs145562579 COSM3212876 |
97 | D>N | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA375378391 rs143926538 |
98 | S>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5301904 RCV002298799 RCV000883926 rs143926538 |
98 | S>L | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA375378412 rs142654869 |
100 | P>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5301906 rs142654869 |
100 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs771980295 CA5301905 |
100 | P>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 101 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA375378451 rs1205060414 |
103 | K>Q | No |
ClinGen gnomAD |
|
|
CA5301909 rs372809223 |
104 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA375378476 rs1588440021 |
105 | S>G | No |
ClinGen Ensembl |
|
|
CA5301910 rs759097390 |
105 | S>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1481562524 CA375378537 |
109 | D>Y | No |
ClinGen gnomAD |
|
|
CA375378546 rs1588440053 |
110 | T>P | No |
ClinGen Ensembl |
|
|
rs763603738 CA5301913 |
111 | L>V | No |
ClinGen ExAC TOPMed |
|
|
CA375378577 rs1168624885 |
112 | A>D | No |
ClinGen gnomAD |
|
|
rs764644794 CA5301914 |
113 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA200898875 rs1047946772 |
114 | T>I | No |
ClinGen gnomAD |
|
|
CA375378602 rs1047946772 |
114 | T>S | No |
ClinGen gnomAD |
|
|
CA375378622 rs1204188537 COSM1701867 |
116 | G>S | skin [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs1479272040 CA375378673 |
119 | Y>* | No |
ClinGen TOPMed gnomAD |
|
|
CA375378677 rs533662277 |
120 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA375378680 rs1304184399 |
120 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs533662277 CA5301917 |
120 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5301918 rs750711297 |
121 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA5301921 rs77329269 |
122 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA200898890 rs77329269 |
122 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375378712 rs1317829813 |
123 | P>S | No |
ClinGen TOPMed |
|
|
CA375378709 rs1317829813 |
123 | P>T | No |
ClinGen TOPMed |
|
|
COSM4007084 CA5301922 rs778821265 |
124 | S>P | urinary_tract [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA5301924 rs758366716 |
125 | T>P | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 126 | M>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1274965157 CA375378745 |
126 | M>V | No |
ClinGen gnomAD |
|
|
rs1357251258 CA375378792 |
129 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1396268669 CA375378807 |
130 | F>C | No |
ClinGen TOPMed |
|
|
rs770534417 CA5301927 |
131 | L>P | No |
ClinGen ExAC |
|
|
rs776000235 CA5301928 |
133 | H>P | No |
ClinGen ExAC |
|
|
CA5301931 rs775944163 |
135 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA375378861 rs372949898 |
135 | V>F | No |
ClinGen TOPMed gnomAD |
|
|
rs372949898 CA200898913 |
135 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA375378885 rs1475760647 |
137 | L>M | No |
ClinGen gnomAD |
|
|
rs140090505 CA5301935 |
139 | G>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs140090505 CA5301933 |
139 | G>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs140090505 CA5301934 |
139 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA200898922 rs1049709369 |
140 | S>C | No |
ClinGen Ensembl |
|
|
CA5301936 rs767699735 |
141 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs750451502 CA5301937 |
143 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5301938 rs756385747 |
145 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA375378989 rs1418256970 |
146 | T>N | No |
ClinGen gnomAD |
|
|
rs1315739296 CA375379019 |
148 | P>L | No |
ClinGen gnomAD |
|
|
rs1430790946 CA375379022 |
149 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA5301940 rs368905369 |
152 | F>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 153 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5301941 rs150284911 |
154 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs78837507 CA5301943 |
155 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs560461496 CA5301945 |
155 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA5301944 rs560461496 |
155 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5301942 rs78837507 |
155 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs745314098 CA5301946 |
157 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375379131 rs951366034 |
158 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
CA200898939 rs951366034 |
158 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1414620986 CA375379147 |
159 | G>D | No |
ClinGen TOPMed |
|
|
rs1588440461 CA375379141 |
159 | G>S | No |
ClinGen Ensembl |
|
| TCGA novel | 160 | M>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1376447537 CA375379155 |
160 | M>V | No |
ClinGen TOPMed |
|
|
rs769515561 CA5301947 |
162 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779785796 CA5301948 |
164 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1241436394 CA375379230 |
165 | C>Y | No |
ClinGen gnomAD |
|
|
CA375379251 rs754085243 |
167 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
rs754085243 CA200898945 |
167 | K>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1184678414 CA375379258 |
167 | K>R | No |
ClinGen gnomAD |
|
|
rs1468878225 CA375379303 |
170 | K>M | No |
ClinGen TOPMed gnomAD |
|
|
CA375379301 rs1468878225 |
170 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1027855830 CA200899187 |
171 | V>A | No |
ClinGen TOPMed |
|
|
CA5301979 rs142421593 |
171 | V>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs142421593 CA375379386 |
171 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1195749893 TCGA novel COSM169651 CA375379391 |
172 | F>L | Variant assessed as Somatic; impact. large_intestine [NCI-TCGA, Cosmic] | No |
NCI-TCGA ClinGen cosmic curated TOPMed |
|
rs762304847 CA200899192 |
174 | T>A | No |
ClinGen Ensembl |
|
|
rs376762177 CA5301982 |
174 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs376762177 RCV001310680 CA5301981 |
174 | T>N | No |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA5301983 rs146007027 |
175 | P>H | No |
ClinGen 1000Genomes ESP ExAC gnomAD |
|
|
CA5301984 rs146007027 |
175 | P>L | No |
ClinGen 1000Genomes ESP ExAC gnomAD |
|
| TCGA novel | 175 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA200899198 rs138653823 CA5301985 |
176 | H>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 176 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA200899202 rs1005136553 |
177 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA375379461 rs1345110952 |
179 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA375379475 rs1405838680 |
180 | V>L | No |
ClinGen gnomAD |
|
|
CA200899209 rs973515605 |
181 | H>L | No |
ClinGen TOPMed gnomAD |
|
|
CA375379493 rs973515605 |
181 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1397252914 CA375379507 |
182 | V>G | No |
ClinGen TOPMed |
|
|
rs778195914 CA5301989 |
183 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1554195 CA5301990 rs148728985 |
183 | R>Q | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs771408008 CA5301991 |
184 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375379523 rs771408008 |
184 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5301992 rs570058270 |
184 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5301994 rs748303990 |
186 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs1269061411 CA375379560 |
187 | S>G | No |
ClinGen gnomAD |
|
| TCGA novel | 188 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA375379586 rs1181677415 |
189 | T>I | No |
ClinGen TOPMed |
|
|
CA5301998 rs192854759 |
190 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 193 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs766382842 CA5302000 |
193 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1364664092 CA375379637 |
194 | C>R | No |
ClinGen gnomAD |
|
|
CA5302003 rs754483976 |
196 | I>F | No |
ClinGen ExAC gnomAD |
|
|
rs754483976 CA5302002 |
196 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA5302006 rs146440020 |
198 | G>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA200899237 rs370269669 |
198 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5302005 rs370269669 |
198 | G>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1367971464 CA375379755 |
200 | T>N | No |
ClinGen gnomAD |
|
|
CA375379773 rs145418687 |
201 | F>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs781610790 CA5302009 |
202 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781610790 CA5302010 |
202 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781610790 CA375379777 |
202 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375379804 rs147726410 |
203 | H>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs62638686 CA5302013 |
204 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
RCV000956759 rs62638686 CA5302012 |
204 | A>T | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA5302014 rs768898305 |
205 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 206 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1450806158 CA375379895 |
209 | Q>K | No |
ClinGen gnomAD |
|
|
rs776772049 CA5302018 |
211 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA375379941 rs1383225691 |
211 | T>S | No |
ClinGen TOPMed |
|
|
rs145867669 CA5302021 |
213 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5302023 rs763764108 |
214 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs148996720 CA5302022 |
214 | H>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5302024 rs373796028 |
216 | Q>H | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA375380137 rs1430002750 |
217 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA200899508 rs1016682120 |
218 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA5302062 rs762784268 |
218 | R>H | No |
ClinGen ExAC |
|
|
CA375380145 rs1016682120 |
218 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
rs374075090 CA5302063 |
220 | F>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs142322678 CA5302064 |
221 | E>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs371395428 CA200899518 |
222 | C>R | No |
ClinGen ESP TOPMed |
|
|
rs1462798363 CA375380180 |
223 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs367947845 CA5302065 |
223 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs367947845 CA200899523 |
223 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs767105897 CA5302066 |
224 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs371084332 CA5302067 |
226 | G>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA375380218 rs1367615343 |
228 | A>P | No |
ClinGen gnomAD |
|
|
rs201349915 CA200899535 |
231 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs761044764 VAR_035556 CA5302068 COSM32833 |
231 | R>H | large_intestine a colorectal cancer sample; somatic mutation [Cosmic, UniProt] | No |
ClinGen cosmic curated UniProt ExAC TOPMed dbSNP gnomAD |
|
rs754439744 CA5302070 |
232 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA375380277 rs754439744 |
232 | S>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1554724654 CA375380303 |
234 | T>M | No |
ClinGen Ensembl |
|
|
rs752776987 CA200899572 |
237 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs752776987 CA5302073 |
237 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs986660744 CA200899573 |
238 | H>Q | No |
ClinGen TOPMed |
|
|
rs758726712 CA5302074 |
239 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1196364560 CA375380453 |
245 | T>M | No |
ClinGen TOPMed |
|
|
rs1201544876 CA375380461 |
246 | R>Q | No |
ClinGen TOPMed |
|
|
CA5302076 rs745670434 |
246 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA200899604 rs910795219 |
247 | P>L | No |
ClinGen gnomAD |
|
|
CA375380488 rs1170867202 |
248 | Y>S | No |
ClinGen gnomAD |
|
|
rs1364041454 CA375380526 |
250 | C>Y | No |
ClinGen gnomAD |
|
|
rs1302101616 CA375380543 |
251 | Q>R | No |
ClinGen gnomAD |
|
|
CA200899605 rs944694471 |
252 | F>Y | No |
ClinGen TOPMed |
|
|
rs749288375 CA5302079 |
254 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765446969 CA5302078 |
254 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768451177 CA5302080 |
256 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA5302081 rs773869692 |
256 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA375380652 rs1299732331 |
258 | H>N | No |
ClinGen TOPMed gnomAD |
|
|
rs866282944 CA200899615 |
261 | S>F | No |
ClinGen Ensembl |
|
| TCGA novel | 262 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1053415693 CA200899624 |
267 | T>I | No |
ClinGen gnomAD |
|
|
rs766810669 CA5302086 |
269 | I>T | No |
ClinGen ExAC |
|
|
CA5302085 rs543334869 |
269 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA375380880 rs1465414678 |
271 | T>S | No |
ClinGen gnomAD |
|
|
CA5302108 rs759753475 |
274 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA5302109 rs543214484 |
275 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 276 | H>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5302111 rs763548823 |
279 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
CA375381198 rs1166124418 |
280 | V>L | No |
ClinGen TOPMed |
|
|
rs753669252 CA5302116 COSM1701868 |
282 | G>E | skin [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA5302114 rs762113108 CA5302115 COSM3413407 |
282 | G>R | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD NCI-TCGA |
|
rs753669252 CA5302117 |
282 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1439794611 CA375381225 |
283 | K>Q | No |
ClinGen gnomAD |
|
|
CA375381242 rs1279137850 |
284 | A>S | No |
ClinGen gnomAD |
|
|
CA375381260 rs1197266637 |
286 | S>N | No |
ClinGen TOPMed |
|
|
rs1041169993 CA200900171 |
287 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1230296068 CA375381289 |
288 | S>N | No |
ClinGen gnomAD |
|
| TCGA novel | 288 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA375381325 rs1375064224 |
291 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs74332772 CA200900179 |
293 | T>P | No |
ClinGen Ensembl |
|
|
CA375381377 rs1225851256 |
295 | S>G | No |
ClinGen gnomAD |
|
|
CA200900184 rs990886827 |
296 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA5302122 rs537470322 |
296 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA5302121 rs537470322 |
296 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770622297 CA5302123 |
297 | K>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770622297 CA200900193 |
297 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1309426757 CA375381442 |
300 | G>D | No |
ClinGen TOPMed |
|
| TCGA novel | 302 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA375381497 rs1426521584 |
304 | F>V | No |
ClinGen gnomAD |
|
|
CA375381538 rs1390492908 |
306 | C>Y | No |
ClinGen TOPMed |
|
|
rs775963992 CA375381575 |
308 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5302129 rs769236543 |
310 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA375381633 rs1307228755 |
312 | G>S | No |
ClinGen gnomAD |
|
|
CA5302130 rs774517040 COSM255919 |
315 | R>C | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA5302131 rs761729738 COSM296000 |
315 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs955174616 CA200900205 |
318 | D>H | No |
ClinGen Ensembl |
|
|
rs760858233 CA5302134 |
320 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5302133 rs750680851 |
320 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs369095339 CA5302137 |
321 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369095339 CA5302136 |
321 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM1106338 CA5302135 rs765068455 |
321 | R>W | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA5302139 rs751095810 |
322 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777505501 CA5302138 |
322 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs756778026 COSM753304 CA5302140 |
323 | R>C | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA5302141 rs373040348 |
323 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs373040348 CA5302142 |
323 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1281439058 CA375381855 |
325 | S>G | No |
ClinGen TOPMed |
|
|
rs1231376875 CA375381856 |
325 | S>N | No |
ClinGen TOPMed |
|
|
rs1474417793 CA375381956 |
330 | K>N | No |
ClinGen gnomAD |
|
| TCGA novel | 331 | K>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs749626626 CA5302145 |
331 | K>L | No |
ClinGen ExAC gnomAD |
|
|
CA5302146 rs769206886 |
331 | K>W | No |
ClinGen ExAC gnomAD |
1 associated diseases with Q5VTD9
[MIM: 187900]: Bleeding disorder, platelet-type, 17 (BDPLT17)
An autosomal dominant disorder characterized by increased bleeding tendency due to platelet dysfunction, and associated with macrothrombocytopenia and red cell anisopoikilocytosis. Platelets appear abnormal on light microscopy, while electron microscopy shows a heterogeneous decrease of alpha granules within platelets. Bone marrow biopsy shows increased numbers of abnormal megakaryocytes, suggesting a defect in megakaryopoiesis and platelet production. The severity of bleeding is variable with some affected individuals experiencing spontaneous bleeding while other exhibit only abnormal bleeding with surgery. {ECO:0000269|PubMed:23927492, ECO:0000269|PubMed:24325358}. Note=The disease is caused by variants affecting the gene represented in this entry.
Without disease ID
- An autosomal dominant disorder characterized by increased bleeding tendency due to platelet dysfunction, and associated with macrothrombocytopenia and red cell anisopoikilocytosis. Platelets appear abnormal on light microscopy, while electron microscopy shows a heterogeneous decrease of alpha granules within platelets. Bone marrow biopsy shows increased numbers of abnormal megakaryocytes, suggesting a defect in megakaryopoiesis and platelet production. The severity of bleeding is variable with some affected individuals experiencing spontaneous bleeding while other exhibit only abnormal bleeding with surgery. {ECO:0000269|PubMed:23927492, ECO:0000269|PubMed:24325358}. Note=The disease is caused by variants affecting the gene represented in this entry.
6 regional properties for Q5VTD9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger C2H2-type | 163 - 191 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 192 - 219 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 220 - 247 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 248 - 275 | IPR013087-4 |
| domain | Zinc finger C2H2-type | 276 - 303 | IPR013087-5 |
| domain | Zinc finger C2H2-type | 304 - 330 | IPR013087-6 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| nuclear matrix | The dense fibrillar network lying on the inner side of the nuclear membrane. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| transcription regulator complex | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription activator activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| metal ion binding | Binding to a metal ion. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
| RNA polymerase II-specific DNA-binding transcription factor binding | Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. |
| sequence-specific double-stranded DNA binding | Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| negative regulation of G1/S transition of mitotic cell cycle | Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. |
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| regulation of hemopoiesis | Any process that modulates the frequency, rate or extent of hemopoiesis. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
177 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08DS3 | OSR1 | Protein odd-skipped-related 1 | Bos taurus (Bovine) | PR |
| Q2VWH6 | FEZF2 | Fez family zinc finger protein 2 | Bos taurus (Bovine) | PR |
| A6QNZ0 | ZSCAN26 | Zinc finger and SCAN domain-containing protein 26 | Bos taurus (Bovine) | PR |
| A7MBI1 | ZFP69 | Zinc finger protein 69 homolog | Bos taurus (Bovine) | PR |
| Q08705 | CTCF | Transcriptional repressor CTCF | Gallus gallus (Chicken) | PR |
| O42409 | GFI1B | Zinc finger protein Gfi-1b | Gallus gallus (Chicken) | PR |
| A2T6W2 | ZNF449 | Zinc finger protein 449 | Pan troglodytes (Chimpanzee) | PR |
| Q9U405 | grau | Transcription factor grauzone | Drosophila melanogaster (Fruit fly) | PR |
| Q7K0S9 | sug | Zinc finger protein GLIS2 homolog | Drosophila melanogaster (Fruit fly) | PR |
| P20385 | Cf2 | Chorion transcription factor Cf2 | Drosophila melanogaster (Fruit fly) | PR |
| Q86P48 | ATbp | AT-rich binding protein | Drosophila melanogaster (Fruit fly) | PR |
| P28698 | MZF1 | Myeloid zinc finger 1 | Homo sapiens (Human) | PR |
| Q9NTW7 | ZFP64 | Zinc finger protein 64 | Homo sapiens (Human) | PR |
| O14978 | ZNF263 | Zinc finger protein 263 | Homo sapiens (Human) | PR |
| O60304 | ZNF500 | Zinc finger protein 500 | Homo sapiens (Human) | PR |
| P08151 | GLI1 | Zinc finger protein GLI1 | Homo sapiens (Human) | PR |
| Q9UFB7 | ZBTB47 | Zinc finger and BTB domain-containing protein 47 | Homo sapiens (Human) | PR |
| P18146 | EGR1 | Early growth response protein 1 | Homo sapiens (Human) | PR |
| Q9Y5W3 | KLF2 | Krueppel-like factor 2 | Homo sapiens (Human) | PR |
| Q9UNY5 | ZNF232 | Zinc finger protein 232 | Homo sapiens (Human) | PR |
| Q96SZ4 | ZSCAN10 | Zinc finger and SCAN domain-containing protein 10 | Homo sapiens (Human) | PR |
| P17028 | ZNF24 | Zinc finger protein 24 | Homo sapiens (Human) | PR |
| P57682 | KLF3 | Krueppel-like factor 3 | Homo sapiens (Human) | PR |
| P25490 | YY1 | Transcriptional repressor protein YY1 | Homo sapiens (Human) | SS |
| O43296 | ZNF264 | Zinc finger protein 264 | Homo sapiens (Human) | PR |
| P49711 | CTCF | Transcriptional repressor CTCF | Homo sapiens (Human) | PR |
| Q9NQX1 | PRDM5 | PR domain zinc finger protein 5 | Homo sapiens (Human) | PR |
| Q9HBE1 | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 | Homo sapiens (Human) | PR |
| Q8TAX0 | OSR1 | Protein odd-skipped-related 1 | Homo sapiens (Human) | PR |
| Q9UL58 | ZNF215 | Zinc finger protein 215 | Homo sapiens (Human) | PR |
| Q8TBJ5 | FEZF2 | Fez family zinc finger protein 2 | Homo sapiens (Human) | PR |
| Q96SR6 | ZNF382 | Zinc finger protein 382 | Homo sapiens (Human) | PR |
| Q96IT1 | ZNF496 | Zinc finger protein 496 | Homo sapiens (Human) | PR |
| Q96N95 | ZNF396 | Zinc finger protein 396 | Homo sapiens (Human) | PR |
| Q9ULJ3 | ZBTB21 | Zinc finger and BTB domain-containing protein 21 | Homo sapiens (Human) | PR |
| O75840 | KLF7 | Krueppel-like factor 7 | Homo sapiens (Human) | PR |
| Q9H9D4 | ZNF408 | Zinc finger protein 408 | Homo sapiens (Human) | PR |
| Q13127 | REST | RE1-silencing transcription factor | Homo sapiens (Human) | PR |
| Q8IZM8 | ZNF654 | Zinc finger protein 654 | Homo sapiens (Human) | PR |
| Q14526 | HIC1 | Hypermethylated in cancer 1 protein | Homo sapiens (Human) | PR |
| P17022 | ZNF18 | Zinc finger protein 18 | Homo sapiens (Human) | PR |
| Q86XF7 | ZNF575 | Zinc finger protein 575 | Homo sapiens (Human) | PR |
| Q06889 | EGR3 | Early growth response protein 3 | Homo sapiens (Human) | PR |
| Q8NAM6 | ZSCAN4 | Zinc finger and SCAN domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q08ER8 | ZNF543 | Zinc finger protein 543 | Homo sapiens (Human) | PR |
| P17029 | ZKSCAN1 | Zinc finger protein with KRAB and SCAN domains 1 | Homo sapiens (Human) | PR |
| Q8N680 | ZBTB2 | Zinc finger and BTB domain-containing protein 2 | Homo sapiens (Human) | PR |
| O95625 | ZBTB11 | Zinc finger and BTB domain-containing protein 11 | Homo sapiens (Human) | PR |
| Q9NPC7 | MYNN | Myoneurin | Homo sapiens (Human) | PR |
| Q96BV0 | ZNF775 | Zinc finger protein 775 | Homo sapiens (Human) | PR |
| Q8NF99 | ZNF397 | Zinc finger protein 397 | Homo sapiens (Human) | PR |
| Q63HK3 | ZKSCAN2 | Zinc finger protein with KRAB and SCAN domains 2 | Homo sapiens (Human) | PR |
| Q5FWF6 | ZNF789 | Zinc finger protein 789 | Homo sapiens (Human) | PR |
| Q15776 | ZKSCAN8 | Zinc finger protein with KRAB and SCAN domains 8 | Homo sapiens (Human) | PR |
| Q53GI3 | ZNF394 | Zinc finger protein 394 | Homo sapiens (Human) | PR |
| O95125 | ZNF202 | Zinc finger protein 202 | Homo sapiens (Human) | PR |
| Q9H116 | GZF1 | GDNF-inducible zinc finger protein 1 | Homo sapiens (Human) | PR |
| Q8N0Y2 | ZNF444 | Zinc finger protein 444 | Homo sapiens (Human) | PR |
| Q6P9G9 | ZNF449 | Zinc finger protein 449 | Homo sapiens (Human) | PR |
| Q8IW36 | ZNF695 | Zinc finger protein 695 | Homo sapiens (Human) | PR |
| Q6PG37 | ZNF790 | Zinc finger protein 790 | Homo sapiens (Human) | PR |
| Q9NQV6 | PRDM10 | PR domain zinc finger protein 10 | Homo sapiens (Human) | PR |
| Q9Y2D9 | ZNF652 | Zinc finger protein 652 | Homo sapiens (Human) | PR |
| Q5TC79 | ZBTB37 | Zinc finger and BTB domain-containing protein 37 | Homo sapiens (Human) | PR |
| Q9Y4E5 | ZNF451 | E3 SUMO-protein ligase ZNF451 | Homo sapiens (Human) | PR |
| Q8ND82 | ZNF280C | Zinc finger protein 280C | Homo sapiens (Human) | PR |
| Q49AA0 | ZFP69 | Zinc finger protein 69 homolog | Homo sapiens (Human) | PR |
| O43298 | ZBTB43 | Zinc finger and BTB domain-containing protein 43 | Homo sapiens (Human) | PR |
| Q9Y330 | ZBTB12 | Zinc finger and BTB domain-containing protein 12 | Homo sapiens (Human) | PR |
| Q13105 | ZBTB17 | Zinc finger and BTB domain-containing protein 17 | Homo sapiens (Human) | PR |
| P51508 | ZNF81 | Zinc finger protein 81 | Homo sapiens (Human) | PR |
| Q5JNZ3 | ZNF311 | Zinc finger protein 311 | Homo sapiens (Human) | PR |
| Q9BRR0 | ZKSCAN3 | Zinc finger protein with KRAB and SCAN domains 3 | Homo sapiens (Human) | PR |
| Q969J2 | ZKSCAN4 | Zinc finger protein with KRAB and SCAN domains 4 | Homo sapiens (Human) | PR |
| P49910 | ZNF165 | Zinc finger protein 165 | Homo sapiens (Human) | PR |
| Q9Y4X4 | KLF12 | Krueppel-like factor 12 | Homo sapiens (Human) | PR |
| P10074 | ZBTB48 | Telomere zinc finger-associated protein | Homo sapiens (Human) | PR |
| P17010 | ZFX | Zinc finger X-chromosomal protein | Homo sapiens (Human) | PR |
| Q9H5H4 | ZNF768 | Zinc finger protein 768 | Homo sapiens (Human) | PR |
| Q6NSZ9 | ZSCAN25 | Zinc finger and SCAN domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q9Y2L8 | ZKSCAN5 | Zinc finger protein with KRAB and SCAN domains 5 | Homo sapiens (Human) | PR |
| Q86UZ6 | ZBTB46 | Zinc finger and BTB domain-containing protein 46 | Homo sapiens (Human) | PR |
| Q9NX65 | ZSCAN32 | Zinc finger and SCAN domain-containing protein 32 | Homo sapiens (Human) | PR |
| O14771 | ZNF213 | Zinc finger protein 213 | Homo sapiens (Human) | PR |
| Q8IWY8 | ZSCAN29 | Zinc finger and SCAN domain-containing protein 29 | Homo sapiens (Human) | PR |
| Q8NCP5 | ZBTB44 | Zinc finger and BTB domain-containing protein 44 | Homo sapiens (Human) | PR |
| P41182 | BCL6 | B-cell lymphoma 6 protein | Homo sapiens (Human) | PR |
| Q9NQX0 | PRDM6 | Putative histone-lysine N-methyltransferase PRDM6 | Homo sapiens (Human) | PR |
| Q9BU19 | ZNF692 | Zinc finger protein 692 | Homo sapiens (Human) | PR |
| Q08AG5 | ZNF844 | Zinc finger protein 844 | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| P98182 | ZNF200 | Zinc finger protein 200 | Homo sapiens (Human) | PR |
| Q9UK11 | ZNF223 | Zinc finger protein 223 | Homo sapiens (Human) | PR |
| O15156 | ZBTB7B | Zinc finger and BTB domain-containing protein 7B | Homo sapiens (Human) | PR |
| Q6ZMS7 | ZNF783 | Zinc finger protein 783 | Homo sapiens (Human) | PR |
| P59923 | ZNF445 | Zinc finger protein 445 | Homo sapiens (Human) | PR |
| Q8N859 | ZNF713 | Zinc finger protein 713 | Homo sapiens (Human) | PR |
| Q99612 | KLF6 | Krueppel-like factor 6 | Homo sapiens (Human) | PR |
| Q8TD17 | ZNF398 | Zinc finger protein 398 | Homo sapiens (Human) | PR |
| P52739 | ZNF131 | Zinc finger protein 131 | Homo sapiens (Human) | PR |
| A6NGD5 | ZSCAN5C | Zinc finger and SCAN domain-containing protein 5C | Homo sapiens (Human) | PR |
| Q05215 | EGR4 | Early growth response protein 4 | Homo sapiens (Human) | PR |
| Q7Z398 | ZNF550 | Zinc finger protein 550 | Homo sapiens (Human) | PR |
| Q9Y2K1 | ZBTB1 | Zinc finger and BTB domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q96N20 | ZNF75A | Zinc finger protein 75A | Homo sapiens (Human) | PR |
| A6NJL1 | ZSCAN5B | Zinc finger and SCAN domain-containing protein 5B | Homo sapiens (Human) | PR |
| A1YPR0 | ZBTB7C | Zinc finger and BTB domain-containing protein 7C | Homo sapiens (Human) | PR |
| Q9NWS9 | ZNF446 | Zinc finger protein 446 | Homo sapiens (Human) | PR |
| P24278 | ZBTB25 | Zinc finger and BTB domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q96N38 | ZNF714 | Zinc finger protein 714 | Homo sapiens (Human) | PR |
| Q86YH2 | ZNF280B | Zinc finger protein 280B | Homo sapiens (Human) | PR |
| Q05516 | ZBTB16 | Zinc finger and BTB domain-containing protein 16 | Homo sapiens (Human) | PR |
| O08584 | Klf6 | Krueppel-like factor 6 | Mus musculus (Mouse) | PR |
| Q61164 | Ctcf | Transcriptional repressor CTCF | Mus musculus (Mouse) | PR |
| Q810A1 | Znf18 | Zinc finger protein 18 | Mus musculus (Mouse) | PR |
| Q8BGS3 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Mus musculus (Mouse) | PR |
| Q00899 | Yy1 | Transcriptional repressor protein YY1 | Mus musculus (Mouse) | PR |
| P41183 | Bcl6 | B-cell lymphoma 6 protein homolog | Mus musculus (Mouse) | PR |
| Q9DAI4 | Zbtb43 | Zinc finger and BTB domain-containing protein 43 | Mus musculus (Mouse) | PR |
| Q99KZ6 | Znf639 | Zinc finger protein 639 | Mus musculus (Mouse) | PR |
| Q9Z1D9 | Znf394 | Zinc finger protein 394 | Mus musculus (Mouse) | PR |
| Q9CXE0 | Prdm5 | PR domain zinc finger protein 5 | Mus musculus (Mouse) | PR |
| P43300 | Egr3 | Early growth response protein 3 | Mus musculus (Mouse) | PR |
| Q9DAU9 | Znf654 | Zinc finger protein 654 | Mus musculus (Mouse) | PR |
| Q9R1Y5 | Hic1 | Hypermethylated in cancer 1 protein | Mus musculus (Mouse) | PR |
| Q8R0T2 | Znf768 | Zinc finger protein 768 | Mus musculus (Mouse) | PR |
| Q9WVG7 | Osr1 | Protein odd-skipped-related 1 | Mus musculus (Mouse) | PR |
| Q8BI73 | Znf775 | Zinc finger protein 775 | Mus musculus (Mouse) | PR |
| Q8VCZ7 | Zbtb7c | Zinc finger and BTB domain-containing protein 7C | Mus musculus (Mouse) | PR |
| Q91VN1 | Znf24 | Zinc finger protein 24 | Mus musculus (Mouse) | PR |
| Q9DB38 | Znf580 | Zinc finger protein 580 | Mus musculus (Mouse) | PR |
| A7KBS4 | Zscan4d | Zinc finger and SCAN domain containing protein 4D | Mus musculus (Mouse) | PR |
| Q91VW9 | Zkscan3 | Zinc finger protein with KRAB and SCAN domains 3 | Mus musculus (Mouse) | PR |
| P10925 | Zfy1 | Zinc finger Y-chromosomal protein 1 | Mus musculus (Mouse) | PR |
| P08046 | Egr1 | Early growth response protein 1 | Mus musculus (Mouse) | PR |
| Q3TTC2 | Yy2 | Transcription factor YY2 | Mus musculus (Mouse) | PR |
| Q3UTQ7 | Prdm10 | PR domain zinc finger protein 10 | Mus musculus (Mouse) | PR |
| Q6P3Y5 | Znf280c | Zinc finger protein 280C | Mus musculus (Mouse) | PR |
| Q9ERU3 | Znf22 | Zinc finger protein 22 | Mus musculus (Mouse) | PR |
| Q8VIG1 | Rest | RE1-silencing transcription factor | Mus musculus (Mouse) | PR |
| Q9Z1D8 | Zkscan5 | Zinc finger protein with KRAB and SCAN domains 5 | Mus musculus (Mouse) | PR |
| Q8BID6 | Zbtb46 | Zinc finger and BTB domain-containing protein 46 | Mus musculus (Mouse) | PR |
| P17012 | Zfx | Zinc finger X-chromosomal protein | Mus musculus (Mouse) | PR |
| Q9WUK6 | Zbtb18 | Zinc finger and BTB domain-containing protein 18 | Mus musculus (Mouse) | PR |
| O35738 | Klf12 | Krueppel-like factor 12 | Mus musculus (Mouse) | PR |
| B2RXC5 | Znf382 | Zinc finger protein 382 | Mus musculus (Mouse) | PR |
| O08900 | Ikzf3 | Zinc finger protein Aiolos | Mus musculus (Mouse) | PR |
| Q5DU09 | Znf652 | Zinc finger protein 652 | Mus musculus (Mouse) | PR |
| Q5RJ54 | Zscan26 | Zinc finger and SCAN domain-containing protein 26 | Mus musculus (Mouse) | PR |
| Q8BLM0 | Klf8 | Krueppel-like factor 8 | Mus musculus (Mouse) | PR |
| Q99JB0 | Klf7 | Krueppel-like factor 7 | Mus musculus (Mouse) | PR |
| Q8R0A2 | Zbtb44 | Zinc finger and BTB domain-containing protein 44 | Mus musculus (Mouse) | PR |
| P20662 | Zfy2 | Zinc finger Y-chromosomal protein 2 | Mus musculus (Mouse) | PR |
| Q80VJ6 | Zscan4c | Zinc finger and SCAN domain containing protein 4C | Mus musculus (Mouse) | PR |
| Q3URS2 | Zscan4f | Zinc finger and SCAN domain containing protein 4F | Mus musculus (Mouse) | PR |
| Q60980 | Klf3 | Krueppel-like factor 3 | Mus musculus (Mouse) | PR |
| Q8K3J5 | Znf131 | Zinc finger protein 131 | Mus musculus (Mouse) | PR |
| O70237 | Gfi1b | Zinc finger protein Gfi-1b | Mus musculus (Mouse) | PR |
| Q9Z2K3 | Znf394 | Zinc finger protein 394 | Rattus norvegicus (Rat) | PR |
| Q642B9 | Znf18 | Zinc finger protein 18 | Rattus norvegicus (Rat) | PR |
| B0K011 | Osr1 | Protein odd-skipped-related 1 | Rattus norvegicus (Rat) | PR |
| D3ZUU2 | Gzf1 | GDNF-inducible zinc finger protein 1 | Rattus norvegicus (Rat) | PR |
| B1WBU4 | Zbtb8a | Zinc finger and BTB domain-containing protein 8A | Rattus norvegicus (Rat) | PR |
| Q7TNK3 | Znf24 | Zinc finger protein 24 | Rattus norvegicus (Rat) | PR |
| O35819 | Klf6 | Krueppel-like factor 6 | Rattus norvegicus (Rat) | PR |
| Q9R1D1 | Ctcf | Transcriptional repressor CTCF | Rattus norvegicus (Rat) | PR |
| P43301 | Egr3 | Early growth response protein 3 | Rattus norvegicus (Rat) | PR |
| P08154 | Egr1 | Early growth response protein 1 | Rattus norvegicus (Rat) | PR |
| A0JPL0 | Znf382 | Zinc finger protein 382 | Rattus norvegicus (Rat) | PR |
| Q4KLI1 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Rattus norvegicus (Rat) | PR |
| A1L1J6 | Znf652 | Zinc finger protein 652 | Rattus norvegicus (Rat) | PR |
| Q9SHD0 | ZAT4 | Zinc finger protein ZAT4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0P4X6 | zbtb44 | Zinc finger and BTB domain-containing protein 44 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A4II20 | egr1 | Early growth response protein 1 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q6P882 | zbtb8a.2 | Zinc finger and BTB domain-containing protein 8A.2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q567C6 | znf367 | Zinc finger protein 367 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| A7Y7X5 | znf711 | Zinc finger protein 711 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPRSFLVKSK | KAHTYHQPRV | QEDEPLWPPA | LTPVPRDQAP | SNSPVLSTLF | PNQCLDWTNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KREPELEQDQ | NLARMAPAPE | GPIVLSRPQD | GDSPLSDSPP | FYKPSFSWDT | LATTYGHSYR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QAPSTMQSAF | LEHSVSLYGS | PLVPSTEPAL | DFSLRYSPGM | DAYHCVKCNK | VFSTPHGLEV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HVRRSHSGTR | PFACDICGKT | FGHAVSLEQH | THVHSQERSF | ECRMCGKAFK | RSSTLSTHLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IHSDTRPYPC | QFCGKRFHQK | SDMKKHTYIH | TGEKPHKCQV | CGKAFSQSSN | LITHSRKHTG |
| 310 | 320 | ||||
| FKPFSCELCT | KGFQRKVDLR | RHRESQHNLK |