Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5VPE5

Entry ID Method Resolution Chain Position Source
AF-Q5VPE5-F1 Predicted AlphaFoldDB

No variants for Q5VPE5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5VPE5

No associated diseases with Q5VPE5

3 regional properties for Q5VPE5

Type Name Position InterPro Accession
domain Homeobox domain 89 - 153 IPR001356
domain Leucine zipper, homeobox-associated 149 - 192 IPR003106
conserved_site Homeobox, conserved site 124 - 147 IPR017970

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q03014 HHEX Hematopoietically-expressed homeobox protein HHEX Homo sapiens (Human) PR
Q6H6S3 HOX24 Homeobox-leucine zipper protein HOX24 Oryza sativa subsp japonica (Rice) PR
Q7XUJ5 HOX22 Homeobox-leucine zipper protein HOX22 Oryza sativa subsp japonica (Rice) PR
A3BYC1 HOX25 Homeobox-leucine zipper protein HOX25 Oryza sativa subsp japonica (Rice) PR
P46603 HAT9 Homeobox-leucine zipper protein HAT9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M276 ATHB-12 Homeobox-leucine zipper protein ATHB-12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN29 ATHB-52 Homeobox-leucine zipper protein ATHB-52 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MERQGLDLGL SLGLGLTTAA TWPAAGFCLN SGMAEQEVIR RDDVVAATAA EDERFACSPG
70 80 90 100 110 120
SPVSSGSGKR GSGSGSGDEV DDAGCDVGGG GARKKLRLSK DQAAVLEECF KTHHTLTPKQ
130 140 150 160 170 180
KVALAKSLNL RPRQVEVWFQ NRRARTKLKQ TEVDCEHLKR WCDQLADDNR RLHKELAELR
190 200 210 220 230 240
ALKATPTPPA AAPPLTTLTM CLSCKRVANA GVPSPAAAIF PGHPQFLCGF RDHAGAASSS
250
YGGASSGLAK AVRAAR