Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5K4R0

Entry ID Method Resolution Chain Position Source
AF-Q5K4R0-F1 Predicted AlphaFoldDB

No variants for Q5K4R0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5K4R0

No associated diseases with Q5K4R0

14 regional properties for Q5K4R0

Type Name Position InterPro Accession
domain Protein kinase domain 814 - 1095 IPR000719
repeat Leucine-rich repeat 105 - 172 IPR001611-1
repeat Leucine-rich repeat 277 - 336 IPR001611-2
repeat Leucine-rich repeat 421 - 481 IPR001611-3
repeat Leucine-rich repeat, typical subtype 110 - 134 IPR003591-1
repeat Leucine-rich repeat, typical subtype 156 - 182 IPR003591-2
repeat Leucine-rich repeat, typical subtype 299 - 323 IPR003591-3
repeat Leucine-rich repeat, typical subtype 372 - 396 IPR003591-4
repeat Leucine-rich repeat, typical subtype 420 - 443 IPR003591-5
repeat Leucine-rich repeat, typical subtype 444 - 468 IPR003591-6
repeat Leucine-rich repeat, typical subtype 593 - 617 IPR003591-7
active_site Serine/threonine-protein kinase, active site 937 - 949 IPR008271
domain Leucine-rich repeat-containing N-terminal, plant-type 39 - 82 IPR013210
binding_site Protein kinase, ATP binding site 820 - 843 IPR017441

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

3 GO annotations of biological process

Name Definition
brassinosteroid mediated signaling pathway The series of molecular signals mediated by the detection of brassinosteroid.
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A2VDZ3 MEF2A Myocyte-specific enhancer factor 2A Bos taurus (Bovine) SS
Q9W6U8 MEF2A Myocyte-specific enhancer factor 2A Gallus gallus (Chicken) SS
Q06413 MEF2C Myocyte-specific enhancer factor 2C Homo sapiens (Human) EV
Q02078 MEF2A Myocyte-specific enhancer factor 2A Homo sapiens (Human) SS
Q60929 Mef2a Myocyte-specific enhancer factor 2A Mus musculus (Mouse) SS
Q8CFN5 Mef2c Myocyte-specific enhancer factor 2C Mus musculus (Mouse) SS
A2ICN5 MEF2A Myocyte-specific enhancer factor 2A Sus scrofa (Pig) SS
A4UTP7 MEF2C Myocyte-specific enhancer factor 2C Sus scrofa (Pig) SS
Q2MJT0 Mef2a Myocyte-specific enhancer factor 2A Rattus norvegicus (Rat) SS
A0A096MJY4 Mef2c Myocyte-specific enhancer factor 2C Rattus norvegicus (Rat) SS
Q655V4 MADS30 MADS-box transcription factor 30 Oryza sativa subsp japonica (Rice) PR
Q40702 MADS2 MADS-box transcription factor 2 Oryza sativa subsp japonica (Rice) PR
Q1PFA4 AGL30 Agamous-like MADS-box protein AGL30 Arabidopsis thaliana (Mouse-ear cress) PR
P29383 AGL3 Agamous-like MADS-box protein AGL3 Arabidopsis thaliana (Mouse-ear cress) PR
P35632 AP3 Floral homeotic protein APETALA 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q683D7 MAF5 Protein MADS AFFECTING FLOWERING 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FUY6 J MADS-box protein JOINTLESS Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MAGGGGGGGR GEGEGRAATG KRERIAIRRI DNLAARQVTF SKRRRGLFKK AEELSILCDA
70 80 90 100 110 120
EVGLVVFSAT GKLFQFASTS MEQIIDRYNS HSKTLQRAEP SQLDLQGEDS STCARLKEEL
130 140 150 160 170 180
AETSLRLRQM RGEELHRLNV EQLQELEKSL ESGLGSVLKT KSKKILDEID GLERKRMQLI
190 200 210 220 230 240
EENLRLKEQL QVSRMSRMEE MQPGPDSEIV YEEGQSSESV TNASYPRPPP DNDYSSDTSL
RLGLSLFSSK