Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5E9G4

Entry ID Method Resolution Chain Position Source
AF-Q5E9G4-F1 Predicted AlphaFoldDB

No variants for Q5E9G4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5E9G4

No associated diseases with Q5E9G4

14 regional properties for Q5E9G4

Type Name Position InterPro Accession
domain B-box-type zinc finger 94 - 135 IPR000315
domain Zinc finger, RING-type 16 - 61 IPR001841
domain B30.2/SPRY domain 292 - 486 IPR001870
domain SPRY domain 362 - 485 IPR003877
domain Butyrophylin-like, SPRY domain 308 - 325 IPR003879-1
domain Butyrophylin-like, SPRY domain 325 - 342 IPR003879-2
domain Butyrophylin-like, SPRY domain 347 - 371 IPR003879-3
domain Butyrophylin-like, SPRY domain 379 - 392 IPR003879-4
domain Butyrophylin-like, SPRY domain 422 - 446 IPR003879-5
domain Butyrophylin-like, SPRY domain 452 - 470 IPR003879-6
domain SPRY-associated 309 - 361 IPR006574
conserved_site Zinc finger, RING-type, conserved site 31 - 40 IPR017907
domain Zinc finger, C3HC4 RING-type 16 - 60 IPR018957
domain TRIM10, RING-HC finger 9 - 69 IPR042784

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

46 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
E1BJS7 TRIM71 E3 ubiquitin-protein ligase TRIM71 Bos taurus (Bovine) PR
Q7YRV4 TRIM21 E3 ubiquitin-protein ligase TRIM21 Bos taurus (Bovine) PR
Q2T9Z0 TRIM17 E3 ubiquitin-protein ligase TRIM17 Bos taurus (Bovine) PR
Q1PRL4 TRIM71 E3 ubiquitin-protein ligase TRIM71 Gallus gallus (Chicken) PR
Q7YR32 TRIM10 Tripartite motif-containing protein 10 Pan troglodytes (Chimpanzee) PR
O15553 MEFV Pyrin Homo sapiens (Human) SS
Q9BTV5 FSD1 Fibronectin type III and SPRY domain-containing protein 1 Homo sapiens (Human) PR
Q9H2S5 RNF39 RING finger protein 39 Homo sapiens (Human) PR
P19474 TRIM21 E3 ubiquitin-protein ligase TRIM21 Homo sapiens (Human) PR
Q9UJV3 MID2 Probable E3 ubiquitin-protein ligase MID2 Homo sapiens (Human) PR
P29590 PML Protein PML Homo sapiens (Human) PR
Q9C029 TRIM7 E3 ubiquitin-protein ligase TRIM7 Homo sapiens (Human) PR
Q9NQ86 TRIM36 E3 ubiquitin-protein ligase TRIM36 Homo sapiens (Human) PR
Q86UV6 TRIM74 Tripartite motif-containing protein 74 Homo sapiens (Human) PR
Q9UPQ4 TRIM35 E3 ubiquitin-protein ligase TRIM35 Homo sapiens (Human) PR
Q6ZMU5 TRIM72 Tripartite motif-containing protein 72 Homo sapiens (Human) PR
Q86UV7 TRIM73 Tripartite motif-containing protein 73 Homo sapiens (Human) PR
Q8N9V2 TRIML1 Probable E3 ubiquitin-protein ligase TRIML1 Homo sapiens (Human) PR
Q86XT4 TRIM50 E3 ubiquitin-protein ligase TRIM50 Homo sapiens (Human) PR
Q5EBN2 TRIM61 Putative tripartite motif-containing protein 61 Homo sapiens (Human) PR
Q9BZY9 TRIM31 E3 ubiquitin-protein ligase TRIM31 Homo sapiens (Human) PR
Q2Q1W2 TRIM71 E3 ubiquitin-protein ligase TRIM71 Homo sapiens (Human) PR
Q9BXM9 FSD1L FSD1-like protein Homo sapiens (Human) PR
Q8BZT2 Sh3rf2 E3 ubiquitin-protein ligase SH3RF2 Mus musculus (Mouse) PR
Q7TPM3 Trim17 E3 ubiquitin-protein ligase TRIM17 Mus musculus (Mouse) PR
Q1XH17 Trim72 Tripartite motif-containing protein 72 Mus musculus (Mouse) PR
Q60953 Pml Protein PML Mus musculus (Mouse) PR
Q9JJ26 Mefv Pyrin Mus musculus (Mouse) SS
Q99PQ1 Trim12a Tripartite motif-containing protein 12A Mus musculus (Mouse) PR
Q61510 Trim25 E3 ubiquitin/ISG15 ligase TRIM25 Mus musculus (Mouse) PR
Q810I2 Trim50 E3 ubiquitin-protein ligase TRIM50 Mus musculus (Mouse) PR
Q1PSW8 Trim71 E3 ubiquitin-protein ligase TRIM71 Mus musculus (Mouse) PR
Q3TL54 Trim43a Tripartite motif-containing protein 43A Mus musculus (Mouse) PR
P86449 Trim43c Tripartite motif-containing protein 43C Mus musculus (Mouse) PR
Q9WUH5 Trim10 Tripartite motif-containing protein 10 Mus musculus (Mouse) PR
O77666 TRIM26 Tripartite motif-containing protein 26 Sus scrofa (Pig) PR
Q865W2 TRIM50 E3 ubiquitin-protein ligase TRIM50 Sus scrofa (Pig) PR
O19085 TRIM10 Tripartite motif-containing protein 10 Sus scrofa (Pig) PR
Q920M2 Rnf39 RING finger protein 39 Rattus norvegicus (Rat) PR
Q9JJ25 Mefv Pyrin Rattus norvegicus (Rat) SS
A0JPQ4 Trim72 Tripartite motif-containing protein 72 Rattus norvegicus (Rat) PR
Q810I1 Trim50 E3 ubiquitin-protein ligase TRIM50 Rattus norvegicus (Rat) PR
D3ZVM4 Trim71 E3 ubiquitin-protein ligase TRIM71 Rattus norvegicus (Rat) PR
F6QEU4 trim71 E3 ubiquitin-protein ligase TRIM71 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q640S6 trim72 Tripartite motif-containing protein 72 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
E7FAM5 trim71 E3 ubiquitin-protein ligase TRIM71 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MASAASVTSL ADEVNCPVCQ GTLREPVTID CGHNFCRVCL TRYLEITSPD PEEPPTCPLC
70 80 90 100 110 120
KEPFRPGNFR PNWQLANVVE NIERLKLVSQ MDLDEEDVCP EHGEKVYFFC EDDEMQLCVV
130 140 150 160 170 180
CREAWEHRAH TVRFLEDAAG PYREQIQKCL ECLRKEREEI QEIQSRENRR IQVLLTQVAT
190 200 210 220 230 240
KKQKVISEFA HLSQFLEEQQ NILLDQLEKL DEDILKHRDE FDVLVTGEIG RFNTLIEELE
250 260 270 280 290 300
EKKERPAREL LTDIRSTLIR CETRRCRKPV AISPELGQRI RDFPQQAFPL QREMKMFLEK
310 320 330 340 350 360
LSFELDYEPA HISLDPRTSH PKLLLSEDYQ QARFSYKWQK SPDNPQRFDR ATCVLAHGGF
370 380 390 400 410 420
TGGRHTWVVS VDLAHGGSCT LGVVSKDIRR KGELRMRPEE GVWAVRLAWG FVSALSSFPT
430 440 450 460 470 480
RLTLEEQPQQ VRVSIDYEVG WVTFANAVTQ EPIYTFTASF TQKVFPFFGL WGRGSKFSLS
SQEGAATLS