Q5E994
Gene name |
CHMP1B |
Protein name |
Charged multivesicular body protein 1b |
Names |
Chromatin-modifying protein 1b, CHMP1b |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:512033 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5E994
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5E994-F1 | Predicted | AlphaFoldDB |
No variants for Q5E994
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5E994 | |||||
No associated diseases with Q5E994
14 regional properties for Q5E994
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | B-box-type zinc finger | 94 - 135 | IPR000315 |
| domain | Zinc finger, RING-type | 16 - 61 | IPR001841 |
| domain | B30.2/SPRY domain | 292 - 486 | IPR001870 |
| domain | SPRY domain | 362 - 485 | IPR003877 |
| domain | Butyrophylin-like, SPRY domain | 308 - 325 | IPR003879-1 |
| domain | Butyrophylin-like, SPRY domain | 325 - 342 | IPR003879-2 |
| domain | Butyrophylin-like, SPRY domain | 347 - 371 | IPR003879-3 |
| domain | Butyrophylin-like, SPRY domain | 379 - 392 | IPR003879-4 |
| domain | Butyrophylin-like, SPRY domain | 422 - 446 | IPR003879-5 |
| domain | Butyrophylin-like, SPRY domain | 452 - 470 | IPR003879-6 |
| domain | SPRY-associated | 309 - 361 | IPR006574 |
| conserved_site | Zinc finger, RING-type, conserved site | 31 - 40 | IPR017907 |
| domain | Zinc finger, C3HC4 RING-type | 16 - 60 | IPR018957 |
| domain | TRIM10, RING-HC finger | 9 - 69 | IPR042784 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| ESCRT III complex | A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission). |
| late endosome membrane | The lipid bilayer surrounding a late endosome. |
| multivesicular body | A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| endosome transport via multivesicular body sorting pathway | The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment. |
| late endosome to vacuole transport | The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q58CS7 | CHMP3 | Charged multivesicular body protein 3 | Bos taurus (Bovine) | SS |
| Q5ZKX1 | CHMP1B | Charged multivesicular body protein 1b | Gallus gallus (Chicken) | PR |
| Q7LBR1 | CHMP1B | Charged multivesicular body protein 1b | Homo sapiens (Human) | PR |
| Q99LU0 | Chmp1b1 | Charged multivesicular body protein 1b-1 | Mus musculus (Mouse) | PR |
| Q84VG1 | CHMP1 | ESCRT-related protein CHMP1 | Oryza sativa subsp japonica (Rice) | PR |
| Q8LE58 | CHMP1A | ESCRT-related protein CHMP1A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SSM4 | CHMP1B | ESCRT-related protein CHMP1B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6DF27 | chmp1b | Charged multivesicular body protein 1b | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q7ZVB1 | chmp1b | Charged multivesicular body protein 1b | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNMEKHLFN | LKFAAKELGR | SAKKCDKEEK | AEKAKIKKAI | QKGNMEVARI | HAENAIRQKN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QAVNFLRMSA | RVDAVAARVQ | TAVTMGKVTK | SMAGVVKSMD | ATLKTMNLEK | ISALMDKFEH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QFETLDVQTQ | QMEDTMSSTT | TLTTPQGQVD | MLLQEMADEA | GLDLNMELPQ | GQTGSVGTSV |
| 190 | |||||
| ASAEQDELSQ | RLARLRDQV |