Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4UNK8

Entry ID Method Resolution Chain Position Source
AF-Q4UNK8-F1 Predicted AlphaFoldDB

No variants for Q4UNK8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4UNK8

No associated diseases with Q4UNK8

3 regional properties for Q4UNK8

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 4 - 376 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 378 - 557 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 380 - 558 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNQTRVFLIF AWLMVAALLW MEWGKDKAPA NAPTPIASQA VPAARDPDAA APAANVPSAQ
70 80 90 100 110 120
AIPQAGSPAA VPATSTTTAT PATTGAAPAI TLTSDVLRLK LDGRSVLDAE LLQFPQTKDG
130 140 150 160 170 180
TEPVKLLTED AAHPYNATSG WASERSPVPG VGGFRAEQPG TTFELAKGQN TLVVPFVWNG
190 200 210 220 230 240
PNGVSIRRIF TLQRGSYAIS IKDEVINKSD AAWNGYVFRK LSRVPTILSR GMTNPDSFSF
250 260 270 280 290 300
NGATWYSPQE GYERRAFKDY MDDGGLNRQI TGGWVALLQH HFFTAWIPQK DQASLYVLAQ
310 320 330 340 350 360
DGPRDVAELR GPAFTVAPGQ SASTEARLWV GPKLVSLLAK EDVKGLDRVV DYSRFSIMAI
370 380 390 400 410 420
IGQGLFWVLS HLHSFLHNWG WAIIGLVVLL RLALYPLSAA QYKSGAKMRR FQPRLAQLKE
430 440 450 460 470 480
RYGDDRQKYQ QATMELFKKE KINPMGGCLP LLIQMPIFFA LYWVLVESVE LRQAPWLGWI
490 500 510 520 530 540
QDLTARDPYF ILPVLNIAIM WATQKLTPTP GMDPMQAKMM QFMPLVFGVM MAFMPAGLVL
550 560 570
YWVVNGGLGL LIQWWMIRQH GEKPSKIIQA NAK