| actin cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| actin filament bundle assembly |
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. |
| actin filament organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. |
| adult walking behavior |
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg. |
| aggressive behavior |
A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual. |
| alpha-beta T cell differentiation |
The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex. |
| auditory behavior |
The behavior of an organism in response to a sound. |
| Bergmann glial cell differentiation |
The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. |
| canonical NF-kappaB signal transduction |
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. |
| cell-cell adhesion |
The attachment of one cell to another cell via adhesion molecules. |
| cerebellum morphogenesis |
The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. |
| circulatory system development |
The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. |
| dendrite morphogenesis |
The process in which the anatomical structures of a dendrite are generated and organized. |
| dendritic spine maintenance |
The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission. |
| DN4 thymocyte differentiation |
The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-. |
| epidermal growth factor receptor signaling pathway |
The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
| establishment of localization in cell |
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
| exploration behavior |
The specific behavior of an organism in response to a novel environment or stimulus. |
| learning |
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. |
| multicellular organism growth |
The increase in size or mass of an entire multicellular organism, as opposed to cell growth. |
| negative regulation of cell-cell adhesion |
Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. |
| negative regulation of endothelial cell apoptotic process |
Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. |
| negative regulation of Rho protein signal transduction |
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction. |
| neural tube closure |
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. |
| neuroepithelial cell differentiation |
The process in which epiblast cells acquire specialized features of neuroepithelial cells. |
| neuromuscular process controlling balance |
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. |
| neuron differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a neuron. |
| neuron remodeling |
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development. |
| peptidyl-tyrosine phosphorylation |
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. |
| phagocytosis |
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. |
| platelet-derived growth factor receptor signaling pathway |
The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| positive regulation of canonical NF-kappaB signal transduction |
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling. |
| positive regulation of cytosolic calcium ion concentration |
Any process that increases the concentration of calcium ions in the cytosol. |
| positive regulation of ERK1 and ERK2 cascade |
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. |
| positive regulation of establishment of T cell polarity |
Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. |
| positive regulation of interleukin-2 production |
Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. |
| positive regulation of neuron projection development |
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). |
| positive regulation of T cell migration |
Any process that activates or increases the frequency, rate or extent of T cell migration. |
| positive regulation of type II interferon production |
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. |
| positive regulation of Wnt signaling pathway, planar cell polarity pathway |
Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. |
| post-embryonic development |
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. |
| protein localization |
Any process in which a protein is transported to, or maintained in, a specific location. |
| protein phosphorylation |
The process of introducing a phosphate group on to a protein. |
| regulation of extracellular matrix organization |
Any process that modulates the frequency, rate or extent of extracellular matrix organization. |
| reproductive process |
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. |
| Rho protein signal transduction |
The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
| substrate-dependent cell migration, cell extension |
The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell. |
| synapse maturation |
The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development. |
| visual learning |
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue. |
