AiPD: Autoinhibited Protein Database

Q49AA0

Gene name	ZFP69 (ZNF642)
Protein name	Zinc finger protein 69 homolog
Names	Zinc finger protein 642
Species	Homo sapiens (Human)
KEGG Pathway	hsa:339559
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

117-188 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

117-188 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q49AA0

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q49AA0-F1	Predicted				AlphaFoldDB

378 variants for Q49AA0

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA21066145 rs905588778	2	P>S		No	ClinGen TOPMed
CA792896 rs781275835	4	Q>R		No	ClinGen ExAC gnomAD
rs747920239 CA792897	5	L>F		No	ClinGen ExAC gnomAD
rs1356522109 CA339884168	8	T>I		No	ClinGen gnomAD
CA339884164 rs1570011635	8	T>P		No	ClinGen Ensembl
rs777765342 CA792899	11	T>A		No	ClinGen ExAC gnomAD
TCGA novel	12	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM1234396 rs139925087 CA792901	12	E>K	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA792902 rs370110368	14	S>N		No	ClinGen ESP ExAC gnomAD
rs745383450 CA792903	15	T>I		No	ClinGen ExAC gnomAD
rs554589796 CA21066177	17	V>A		No	ClinGen 1000Genomes
CA339884241 rs1341480605	20	Q>R		No	ClinGen gnomAD
rs771695245 CA792904	22	P>S		No	ClinGen ExAC gnomAD
TCGA novel	23	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA792905 rs775061188	24	K>R		No	ClinGen ExAC gnomAD
rs1254557736 CA339884274	25	A>P		No	ClinGen gnomAD
CA339884280 rs1197632620	26	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA339884285 rs1244503124	27	E>K		No	ClinGen gnomAD
CA792906 rs762231690	29	A>S		No	ClinGen ExAC gnomAD
CA339884299 rs762231690	29	A>T		No	ClinGen ExAC gnomAD
CA792907 rs548547006 COSM218446	29	A>V	Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA339884315 rs1166814307	32	W>G		No	ClinGen gnomAD
CA792910 rs767024803	33	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA339884357 rs1343641536	37	K>N		No	ClinGen TOPMed
TCGA novel	38	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767769267 CA792913	39	F>S		No	ClinGen ExAC gnomAD
CA21066267 rs551761308	41	G>R		No	ClinGen Ensembl
CA21066276 rs969927710	43	A>P		No	ClinGen TOPMed gnomAD
CA792926 rs538146379	43	A>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1340295677 CA339884509	46	S>F		No	ClinGen gnomAD
CA339884523 rs1425191036	47	Q>L		No	ClinGen TOPMed
rs1557539674 CA339884569	50	E>D		No	ClinGen Ensembl
CA339884577 rs1243027053	51	D>N		No	ClinGen TOPMed gnomAD
CA339884580 rs1243027053	51	D>Y		No	ClinGen TOPMed gnomAD
CA792928 rs114206274	52	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs114206274 CA339884592	52	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA792929 rs775057897	55	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA339884651 rs1279526574	57	E>K		No	ClinGen TOPMed
rs771601269 CA792931	59	L>*		No	ClinGen ExAC gnomAD
rs1256749565 CA339884682	59	L>S		No	ClinGen gnomAD
rs767536975 CA792932	61	D>E		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	65	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA792935 rs764300752	65	P>R		No	ClinGen ExAC gnomAD
rs753568695 CA792936	66	G>R		No	ClinGen ExAC TOPMed gnomAD
CA792938 COSM172311 rs769989618	68	P>L	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs757099497 CA792937	68	P>T		No	ClinGen ExAC TOPMed gnomAD
rs368379568 CA792941	69	T>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368379568 CA792940	69	T>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1037116976 CA21068123	70	A>V		No	ClinGen TOPMed
CA21072602 rs760835055	75	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1401509329 CA339886171	81	I>V		No	ClinGen gnomAD
rs1214138602 CA339886205	83	I>V		No	ClinGen gnomAD
CA792958 rs754102186	86	T>I		No	ClinGen ExAC TOPMed gnomAD
rs761593978 CA792959	87	Q>E		No	ClinGen ExAC gnomAD
CA792961 rs750246787	89	E>A		No	ClinGen ExAC gnomAD
CA339886330 rs1241375922	89	E>Q		No	ClinGen gnomAD
rs1290825138 CA339886367	90	W>*		No	ClinGen TOPMed
CA792963 rs758202634	90	W>L		No	ClinGen ExAC TOPMed gnomAD
CA792962 rs758202634	90	W>S		No	ClinGen ExAC TOPMed gnomAD
rs1018778213 CA21072631	91	G>R		No	ClinGen TOPMed gnomAD
CA339886420 rs1348615948	92	Q>H		No	ClinGen TOPMed
TCGA novel	92	Q>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339886431 rs1311644004	94	A>T		No	ClinGen TOPMed
CA339886467 rs1187346536	97	H>Y		No	ClinGen TOPMed gnomAD
CA792964 rs116419914	100	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA792965 rs376587289	102	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs145832267 CA792966	102	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs116054135 CA792967	103	E>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA339886577 rs1224573004	103	E>G		No	ClinGen Ensembl
CA792968 rs757680528	104	V>L		No	ClinGen ExAC gnomAD
rs1317165278 CA339886662	108	N>H		No	ClinGen TOPMed
CA21072686 rs984510764	109	Y>F		No	ClinGen Ensembl
rs1398649634 CA339886702	109	Y>H		No	ClinGen TOPMed
CA339886793 rs1173225312	111	N>S		No	ClinGen TOPMed gnomAD
CA792970 rs779359298	112	L>F		No	ClinGen ExAC gnomAD
RCV000946462 CA792971 rs34752670 VAR_033583	113	V>L		No	ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA792972 rs369107838	114	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs766262699 CA793004	117	Y>H		No	ClinGen ExAC TOPMed gnomAD
rs774140468 CA793005	118	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA793008 rs200696975	125	I>L		No	ClinGen ExAC TOPMed gnomAD
rs200047507 CA793009	125	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA339887090 rs1421694745	127	Q>H		No	ClinGen gnomAD
CA21072943 rs918091019	127	Q>P		No	ClinGen Ensembl
CA339887140 rs1447372026	131	G>E		No	ClinGen gnomAD
CA339887161 rs1160044206	133	E>K		No	ClinGen gnomAD
rs760315320 CA793010	135	W>S		No	ClinGen ExAC
CA793011 rs763626748	136	M>V		No	ClinGen ExAC gnomAD
CA339887224 rs1418538152	137	A>T		No	ClinGen gnomAD
rs753596799 CA793012	137	A>V		No	ClinGen ExAC gnomAD
rs758678936 CA793014	138	E>K		No	ClinGen ExAC gnomAD
CA793013 rs758678936	138	E>Q		No	ClinGen ExAC gnomAD
CA793016 rs755438581	140	E>*		No	ClinGen ExAC TOPMed gnomAD
CA339887290 rs1376643286	140	E>V		No	ClinGen gnomAD
CA793017 rs781680395	141	G>V		No	ClinGen ExAC gnomAD
CA339887379 rs1372031312	146	S>I		No	ClinGen TOPMed
CA793018 rs748204975	147	S>*		No	ClinGen ExAC TOPMed gnomAD
rs1325984095 CA339888438	154	E>V		No	ClinGen TOPMed gnomAD
CA21076271 rs944843914	155	T>N		No	ClinGen TOPMed
rs371888521 CA793035	156	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA21076298 rs769119570	157	E>A		No	ClinGen Ensembl
rs41301076 CA793036	157	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1278922283 CA339888532	158	S>T		No	ClinGen gnomAD
rs756132763 CA793038	160	A>G		No	ClinGen ExAC gnomAD
rs777849287 CA793039	161	K>E		No	ClinGen ExAC gnomAD
TCGA novel	162	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1570047520 CA339888614	162	S>R		No	ClinGen Ensembl
CA793042 rs529696394	165	S>L		No	ClinGen ExAC
CA339888745 rs1557559147	166	Q>H		No	ClinGen Ensembl
CA793043 rs574548786	168	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA793044 rs777280499	168	R>H		No	ClinGen ExAC gnomAD
rs777280499 CA21076343	168	R>L		No	ClinGen ExAC gnomAD
rs148895979 CA793046	170	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA339888861 rs1273652120	171	H>R		No	ClinGen gnomAD
rs1557559256 CA339888921	174	M>I		No	ClinGen Ensembl
CA793050 rs772596917	176	E>*		No	ClinGen ExAC TOPMed gnomAD
CA339888949 rs1316408332	176	E>A		No	ClinGen gnomAD
rs772596917 CA793049	176	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs1193762670 CA339888976	177	S>T		No	ClinGen gnomAD
rs1273815850 CA339889055	179	M>I		No	ClinGen gnomAD
rs761253413 CA793051	179	M>K		No	ClinGen ExAC gnomAD
rs764921471 CA793052	180	R>K		No	ClinGen ExAC gnomAD
rs1017164447 CA21076375	181	D>Y		No	ClinGen TOPMed
rs772891274 CA793053	183	I>M		No	ClinGen ExAC gnomAD
CA339889144 rs1266077870	183	I>T		No	ClinGen gnomAD
rs868472357 CA21076385	184	I>M		No	ClinGen TOPMed gnomAD
rs759889298 CA793054	186	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA793056 rs146417933	187	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA339889291 rs1404902493	189	R>T		No	ClinGen gnomAD
CA339889358 rs1470356900	192	S>F		No	ClinGen TOPMed
rs757325035 CA793060	196	D>N		No	ClinGen ExAC gnomAD
rs1180227746 CA339889405	199	E>*		No	ClinGen TOPMed gnomAD
TCGA novel	200	R>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1338955263 CA339889415	200	R>W		No	ClinGen gnomAD
CA793061 rs779277679	201	H>N		No	ClinGen ExAC TOPMed gnomAD
rs746153506 CA793062	202	Q>R		No	ClinGen ExAC gnomAD
rs928994065 CA21076469	203	E>K		No	ClinGen TOPMed
rs896562041 CA21076471	205	C>F		No	ClinGen Ensembl
rs1463161886 CA339889488	207	R>T		No	ClinGen TOPMed
CA793063 rs758710455	208	D>V		No	ClinGen ExAC gnomAD
CA793065 rs140932083	213	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs140932083 CA793064	213	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA793066 rs768589632	214	L>W		No	ClinGen ExAC gnomAD
CA793067 rs376846774	215	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA21076483 rs1014133288	216	H>P		No	ClinGen gnomAD
TCGA novel	217	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1426588525 CA339890064	218	K>N		No	ClinGen gnomAD
CA21076493 rs1020113758	219	R>G		No	ClinGen TOPMed gnomAD
rs138445280 CA793069	219	R>T		No	ClinGen ESP ExAC gnomAD
CA793071 rs762532896	225	K>T		No	ClinGen ExAC TOPMed gnomAD
rs150232367 CA793072	226	F>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1420346917 CA339890215	227	G>W		No	ClinGen gnomAD
rs1434381841 CA339890232	228	E>G		No	ClinGen TOPMed
CA339890248 rs1324777114	229	N>S		No	ClinGen TOPMed
TCGA novel	229	N>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA793073 rs775881240	230	I>N		No	ClinGen ExAC TOPMed gnomAD
CA339890258 rs775881240	230	I>T		No	ClinGen ExAC TOPMed gnomAD
CA793075 rs764636898	231	I>T		No	ClinGen ExAC gnomAD
rs754373216 CA793076	232	V>L		No	ClinGen ExAC TOPMed gnomAD
CA793077 rs757349287	233	H>R		No	ClinGen ExAC gnomAD
rs1312436255 CA339890309	234	S>*		No	ClinGen gnomAD
CA339890317 rs149427370	235	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA793078 rs149427370	235	N>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA339890350 rs1285294240	236	V>G		No	ClinGen gnomAD
COSM1185424 CA793080 rs115439636	238	I>T	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
rs758655116 CA793081	240	Q>*		No	ClinGen ExAC
CA793083 rs746796647	241	R>S		No	ClinGen ExAC gnomAD
CA793082 rs780446998	241	R>T		No	ClinGen ExAC gnomAD
rs1202048802 CA339890444	241	R>W		No	ClinGen gnomAD
CA21076557 rs375909934	243	H>R		No	ClinGen ESP TOPMed
rs1182018765 CA339890493	243	H>Y		No	ClinGen gnomAD
rs1474110948 CA339890540	245	Y>C		No	ClinGen TOPMed
rs200740175 CA21076570	246	D>E		No	ClinGen TOPMed gnomAD
CA339890569 rs1243377718	246	D>G		No	ClinGen TOPMed
CA339890591 rs1362067319	248	P>S		No	ClinGen TOPMed gnomAD
CA339890602 rs1557560338	249	T>A		No	ClinGen Ensembl
rs1280311232 CA339890627	250	K>E		No	ClinGen TOPMed
CA793088 rs115883454	251	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs370592889 CA793087	251	R>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1394622796 CA339890669	252	N>D		No	ClinGen TOPMed gnomAD
CA21076601 rs911676554	258	L>M		No	ClinGen gnomAD
rs776781729 CA21076603	259	I>L		No	ClinGen ExAC TOPMed gnomAD
CA793090 rs776781729	259	I>V		No	ClinGen ExAC TOPMed gnomAD
CA793091 rs773919880	260	N>D		No	ClinGen ExAC TOPMed gnomAD
rs548238668 CA793093	261	H>L		No	ClinGen 1000Genomes ExAC gnomAD
rs373120900 CA21076618	261	H>Q		No	ClinGen ESP TOPMed gnomAD
CA793092 rs761099928	261	H>Y		No	ClinGen ExAC gnomAD
CA793095 rs762347462	265	Y>*		No	ClinGen ExAC gnomAD
rs116083793 CA793094	265	Y>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA339890931 rs1239706330 CA339890933	266	I>L		No	ClinGen gnomAD
CA339890932 rs1239706330	266	I>V		No	ClinGen gnomAD
CA793096 rs142178729	270	T>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs375433261 CA21076646	271	Y>F		No	ClinGen ESP TOPMed
CA339891040 rs1248537483	272	E>*		No	ClinGen gnomAD
CA339891047 rs1194121339	272	E>D		No	ClinGen gnomAD
CA793098 rs763174967	273	C>S		No	ClinGen ExAC TOPMed gnomAD
CA339891066 rs1200249549	273	C>Y		No	ClinGen gnomAD
TCGA novel	274	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339891126 rs1173292271	275	I>M		No	ClinGen gnomAD
rs1468622951 CA339891120	275	I>T		No	ClinGen gnomAD
TCGA novel	279	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774870329	279	I>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs751794224 CA793101	279	I>T		No	ClinGen ExAC gnomAD
rs368571091 CA793102	280	F>Y		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	281	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	281	K>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA793104 rs780790718	283	P>L		No	ClinGen ExAC gnomAD
rs780790718 CA339891269	283	P>R		No	ClinGen ExAC gnomAD
rs926622370 CA21076718	285	H>Y		No	ClinGen Ensembl
TCGA novel	288	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA793108 rs777707369	290	M>I		No	ClinGen ExAC TOPMed gnomAD
CA21076734 rs149951455	290	M>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA793107 rs149951455	290	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs748769511 CA793109	291	R>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	291	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21076735 rs868753187	292	I>T		No	ClinGen Ensembl
CA339891420 rs1275456660	293	H>N		No	ClinGen TOPMed
rs1438885992 CA339891477	296	E>G		No	ClinGen gnomAD
TCGA novel	297	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339891540 rs1249804859	300	R>T		No	ClinGen TOPMed gnomAD
CA339891574 rs1210498170	302	K>R		No	ClinGen gnomAD
rs1266690303 CA339891589	303	E>K		No	ClinGen gnomAD
CA339891641 rs1479745792	306	R>M		No	ClinGen gnomAD
TCGA novel	307	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1291303896 CA339891661	308	F>L		No	ClinGen TOPMed
CA793111 rs140790385	308	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	315	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1445589347 CA339891777	315	S>R		No	ClinGen Ensembl
rs778618803 CA793113	316	T>R		No	ClinGen ExAC gnomAD
rs1307156552 CA339891821	318	Q>H		No	ClinGen TOPMed
CA339891828 rs1475105025	319	R>K		No	ClinGen TOPMed gnomAD
rs1419527806 CA339891863	321	H>D		No	ClinGen TOPMed gnomAD
rs1419527806 CA339891862	321	H>N		No	ClinGen TOPMed gnomAD
rs148842734 CA793118	321	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs773896680 CA793120	323	G>S		No	ClinGen ExAC gnomAD
CA339891924 rs1570049329	325	K>N		No	ClinGen Ensembl
CA793122 rs766427272	326	P>R		No	ClinGen ExAC gnomAD
CA793121 rs763121799	326	P>S		No	ClinGen ExAC gnomAD
CA339891925 rs763121799	326	P>T		No	ClinGen ExAC gnomAD
rs144613252 CA793124	328	E>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs866715032 CA21076802	330	E>K		No	ClinGen Ensembl
CA793125 rs759608631	332	C>S		No	ClinGen ExAC TOPMed gnomAD
rs902993702 CA21076814	334	K>R		No	ClinGen TOPMed
CA21076817 rs537310236	338	H>R		No	ClinGen gnomAD
rs767810347 CA793126	339	R>C		No	ClinGen ExAC TOPMed gnomAD
CA793127 rs752437339 COSM1473979	339	R>H	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA339892023 rs1185152636	340	S>*		No	ClinGen gnomAD
rs1185152636 CA339892024	340	S>L		No	ClinGen gnomAD
CA793130 rs370243933	346	H>R		No	ClinGen ESP ExAC gnomAD
rs1422180455 CA339892071	347	R>T		No	ClinGen gnomAD
CA793132 rs778221924	349	H>Q		No	ClinGen ExAC gnomAD
rs745417353 CA793134	350	T>I		No	ClinGen ExAC TOPMed gnomAD
CA793133 rs745417353	350	T>N		No	ClinGen ExAC TOPMed gnomAD
rs745417353 CA339892091	350	T>S		No	ClinGen ExAC TOPMed gnomAD
CA21076888 rs201996049	353	K>E		No	ClinGen 1000Genomes
CA339892118 rs1286907229	354	P>L		No	ClinGen gnomAD
CA21076889 rs939332736	355	Y>C		No	ClinGen TOPMed
rs770350728 CA793137	356	V>I		No	ClinGen ExAC gnomAD
rs953411599 CA21076897	357	C>Y		No	ClinGen Ensembl
CA339892149 rs1357430627	359	K>T		No	ClinGen gnomAD
rs1221789050 CA339892159	360	C>Y		No	ClinGen TOPMed
CA793138 rs374949421	361	Q>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA339892179 rs1286751614	363	A>S		No	ClinGen gnomAD
rs1007265976 CA21076904	364	F>L		No	ClinGen Ensembl
rs1557561780 CA339892193	365	S>N		No	ClinGen Ensembl
rs1214220438 CA339892215	368	I>V		No	ClinGen gnomAD
CA339892277 rs1182124439	376	T>I		No	ClinGen gnomAD
CA339892274 rs1557561850	376	T>S		No	ClinGen Ensembl
CA339892282 rs1292713672	377	H>R		No	ClinGen Ensembl
COSM426268 rs1242140787 CA339892291	378	S>F	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA339892295 rs1442301941	379	G>E		No	ClinGen gnomAD
rs771472344 CA793141	380	E>G		No	ClinGen ExAC gnomAD
rs759681560 CA793143	382	P>L		No	ClinGen ExAC TOPMed gnomAD
CA21076969 rs759681560	382	P>R		No	ClinGen ExAC TOPMed gnomAD
CA793144 rs767610239	383	F>L		No	ClinGen ExAC TOPMed gnomAD
rs1159032879 CA339892333	385	C>S		No	ClinGen TOPMed
CA793145 rs775725230	386	N>S		No	ClinGen ExAC gnomAD
rs760455369 CA793146	389	G>W		No	ClinGen ExAC gnomAD
rs763822040 CA793147	392	F>I		No	ClinGen ExAC gnomAD
rs1342481072 CA339892447	396	R>G		No	ClinGen gnomAD
rs753638413 CA793148	397	H>Y		No	ClinGen ExAC gnomAD
CA339892513 rs1570050163	400	E>G		No	ClinGen Ensembl
CA793152 rs371971720	402	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs559506806 CA21077025	402	I>R		No	ClinGen ExAC TOPMed gnomAD
CA793151 rs559506806	402	I>T		No	ClinGen ExAC TOPMed gnomAD
CA793150 rs201949234	402	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA793153 rs757968094	403	R>K		No	ClinGen ExAC gnomAD
rs1557562230 CA339892605	407	G>A		No	ClinGen Ensembl
CA339892603 rs1557562230	407	G>E		No	ClinGen Ensembl
CA793156 rs41303439 CA793155	407	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC TOPMed gnomAD NCI-TCGA
rs749700554 CA793158	408	E>K		No	ClinGen ExAC gnomAD
CA339892660 rs1485652858	411	Y>C		No	ClinGen TOPMed gnomAD
rs138821500 CA793159	412	A>G		No	ClinGen ESP ExAC TOPMed
rs1233359918 CA339892698	414	T>A		No	ClinGen TOPMed
rs1414889465 CA339892707	414	T>I		No	ClinGen TOPMed gnomAD
CA339892705 rs1414889465	414	T>S		No	ClinGen TOPMed gnomAD
rs1258765712 CA339892708	415	A>T		No	ClinGen gnomAD
CA339892776 rs1570050460	420	F>V		No	ClinGen Ensembl
CA793161 rs745900629	422	H>Y		No	ClinGen ExAC gnomAD
rs536644133 CA21077158	423	R>G		No	ClinGen TOPMed gnomAD
CA793163 rs775673778	424	A>V	Variant assessed as Somatic; 4.622e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs368253242 CA793165	425	Y>S		No	ClinGen ESP ExAC gnomAD
CA339892949 rs1223360550	428	H>Y		No	ClinGen gnomAD
CA339892978 rs1281811029	429	H>L		No	ClinGen gnomAD
CA339893026 rs1200199296	432	I>L		No	ClinGen gnomAD
CA21077205 rs201603138	433	H>R		No	ClinGen 1000Genomes
CA793167 rs776366189	433	H>Y		No	ClinGen ExAC TOPMed gnomAD
rs765054547 CA793169	434	T>I		No	ClinGen ExAC TOPMed gnomAD
rs757834688 CA793171	437	R>K		No	ClinGen ExAC gnomAD
rs1261168661 CA339893145	437	R>S		No	ClinGen TOPMed
CA339893203 rs1198535330	441	C>R		No	ClinGen gnomAD
CA793172 rs765929094	441	C>Y		No	ClinGen ExAC gnomAD
rs1570050831 CA339893263	444	C>R		No	ClinGen Ensembl
CA793173 rs751117427	444	C>Y		No	ClinGen ExAC gnomAD
CA339893274 rs1171738595	445	G>R		No	ClinGen gnomAD
CA21077310 rs372043105	446	K>E		No	ClinGen ESP TOPMed gnomAD
CA21077315 rs865973983	447	A>T		No	ClinGen Ensembl
rs139946046 CA21077316	450	Q>*		No	ClinGen ESP
rs781013030 CA793175	451	R>G		No	ClinGen ExAC TOPMed gnomAD
rs749590510 CA793176	451	R>T		No	ClinGen ExAC gnomAD
CA339893416 rs1570050968	453	H>P		No	ClinGen Ensembl
CA339893461 rs1435340814	456	N>H		No	ClinGen TOPMed gnomAD
rs938242289 CA21077325 COSM1317528	457	H>R	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated Ensembl
CA793177 rs757675815	458	K>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA339893492 rs1281907651	459	T>I		No	ClinGen gnomAD
CA793178 rs779281215	461	H>R		No	ClinGen ExAC TOPMed gnomAD
rs746442656 CA793179	462	T>S		No	ClinGen ExAC gnomAD
CA793180 rs772464976	464	V>A		No	ClinGen ExAC gnomAD
CA793182 rs747117509	466	A>V		No	ClinGen ExAC gnomAD
rs917897560 CA21077357 COSM909460	471	R>C	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA793185 rs149904505	471	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs769690997 CA793186	472	C>F		No	ClinGen ExAC gnomAD
CA339893683 rs1317948618	474	K>R		No	ClinGen TOPMed gnomAD
rs1374051840 CA339893714	477	R>W		No	ClinGen TOPMed
CA339893726 rs772897701	478	H>N		No	ClinGen ExAC TOPMed gnomAD
CA793188 rs376696045	478	H>R		No	ClinGen ESP ExAC gnomAD
rs772897701 CA793187	478	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA21077367 rs199725751	482	F>L		No	ClinGen 1000Genomes
rs1466718921 CA339893787	482	F>L		No	ClinGen TOPMed
CA339893799 rs1372770917	483	K>R		No	ClinGen TOPMed
rs751064339 CA793190	486	Q>E		No	ClinGen ExAC gnomAD
CA21077392 rs201801948	487	R>G		No	ClinGen 1000Genomes
CA339893867 rs1430449314	488	H>Y		No	ClinGen TOPMed
rs759165203 CA793191	489	H>N		No	ClinGen ExAC TOPMed gnomAD
CA339893881 rs759165203	489	H>Y		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	490	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767243679 CA793193	493	K>E		No	ClinGen ExAC gnomAD
CA21077417 rs867279066	493	K>R		No	ClinGen Ensembl
CA793194 rs752457187	494	P>H		No	ClinGen ExAC gnomAD
CA793195 rs752457187	494	P>L		No	ClinGen ExAC gnomAD
CA339893964 rs1244582788	495	Y>*		No	ClinGen TOPMed gnomAD
rs779276148 CA793196	495	Y>F		No	ClinGen ExAC TOPMed gnomAD
rs898578858 CA21077449	495	Y>H		No	ClinGen TOPMed gnomAD
CA793197 rs147751046	496	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA339893987 rs1228885243	497	C>G		No	ClinGen TOPMed
rs148293066 CA793200	499	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs1445046177 CA339894025	500	C>Y		No	ClinGen gnomAD
rs768791324 CA793201	501	G>R		No	ClinGen ExAC TOPMed gnomAD
CA339894094 rs1315154555	505	S>N		No	ClinGen TOPMed
CA793203 rs116699307	506	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1018581924 CA21077513	510	L>F		No	ClinGen Ensembl
rs372520998 CA21077539	511	S>G		No	ClinGen ESP TOPMed
CA793207 rs773018357	511	S>N		No	ClinGen ExAC TOPMed gnomAD
CA793208 rs200916688	512	R>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA793209 rs770968441	512	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA339894213 rs1164348217	513	H>Q		No	ClinGen TOPMed
rs780591542 CA21077560	513	H>R		No	ClinGen Ensembl
CA793210 rs774466943	514	H>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA339894295 rs1451375399	517	H>Q		No	ClinGen gnomAD
rs1312316242 CA339894306	518	R>K		No	ClinGen gnomAD
CA21077580 rs984998202	518	R>S		No	ClinGen Ensembl
CA793212 rs759108080	520	N>H		No	ClinGen ExAC gnomAD
rs752158456 CA793214	521	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	522	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA793216 rs572985366 COSM909463	523	R>*	endometrium [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs572985366 CA793215	523	R>G		No	ClinGen ExAC TOPMed gnomAD
rs750782473 CA793217	523	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs758806052 CA793218	524	N>D		No	ClinGen ExAC TOPMed gnomAD
rs1181921549 CA339894422	525	K>E		No	ClinGen TOPMed gnomAD

No associated diseases with Q49AA0

2 regional properties for Q49AA0

Type	Name	Position	InterPro Accession
domain	Protein kinase domain	133 - 388	IPR000719
active_site	Serine/threonine-protein kinase, active site	249 - 261	IPR008271

Functions

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

1 GO annotations of cellular component

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name	Definition
DNA-binding transcription factor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
DNA-binding transcription repressor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.
metal ion binding	Binding to a metal ion.
RNA polymerase II transcription regulatory region sequence-specific DNA binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.

4 GO annotations of biological process

Name	Definition
lipid metabolic process	The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
negative regulation of transcription by RNA polymerase II	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
regulation of lipid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
regulation of transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

177 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q08DS3	OSR1	Protein odd-skipped-related 1	Bos taurus (Bovine)	PR
Q2VWH6	FEZF2	Fez family zinc finger protein 2	Bos taurus (Bovine)	PR
A6QNZ0	ZSCAN26	Zinc finger and SCAN domain-containing protein 26	Bos taurus (Bovine)	PR
A7MBI1	ZFP69	Zinc finger protein 69 homolog	Bos taurus (Bovine)	PR
Q08705	CTCF	Transcriptional repressor CTCF	Gallus gallus (Chicken)	PR
O42409	GFI1B	Zinc finger protein Gfi-1b	Gallus gallus (Chicken)	PR
A2T6W2	ZNF449	Zinc finger protein 449	Pan troglodytes (Chimpanzee)	PR
Q9U405	grau	Transcription factor grauzone	Drosophila melanogaster (Fruit fly)	PR
Q7K0S9	sug	Zinc finger protein GLIS2 homolog	Drosophila melanogaster (Fruit fly)	PR
P20385	Cf2	Chorion transcription factor Cf2	Drosophila melanogaster (Fruit fly)	PR
Q86P48	ATbp	AT-rich binding protein	Drosophila melanogaster (Fruit fly)	PR
P28698	MZF1	Myeloid zinc finger 1	Homo sapiens (Human)	PR
Q9NTW7	ZFP64	Zinc finger protein 64	Homo sapiens (Human)	PR
O14978	ZNF263	Zinc finger protein 263	Homo sapiens (Human)	PR
O60304	ZNF500	Zinc finger protein 500	Homo sapiens (Human)	PR
P08151	GLI1	Zinc finger protein GLI1	Homo sapiens (Human)	PR
Q9UFB7	ZBTB47	Zinc finger and BTB domain-containing protein 47	Homo sapiens (Human)	PR
P18146	EGR1	Early growth response protein 1	Homo sapiens (Human)	PR
Q9Y5W3	KLF2	Krueppel-like factor 2	Homo sapiens (Human)	PR
Q9UNY5	ZNF232	Zinc finger protein 232	Homo sapiens (Human)	PR
Q96SZ4	ZSCAN10	Zinc finger and SCAN domain-containing protein 10	Homo sapiens (Human)	PR
P17028	ZNF24	Zinc finger protein 24	Homo sapiens (Human)	PR
P57682	KLF3	Krueppel-like factor 3	Homo sapiens (Human)	PR
P25490	YY1	Transcriptional repressor protein YY1	Homo sapiens (Human)	SS
O43296	ZNF264	Zinc finger protein 264	Homo sapiens (Human)	PR
P49711	CTCF	Transcriptional repressor CTCF	Homo sapiens (Human)	PR
Q9NQX1	PRDM5	PR domain zinc finger protein 5	Homo sapiens (Human)	PR
Q9HBE1	PATZ1	POZ-, AT hook-, and zinc finger-containing protein 1	Homo sapiens (Human)	PR
Q8TAX0	OSR1	Protein odd-skipped-related 1	Homo sapiens (Human)	PR
Q9UL58	ZNF215	Zinc finger protein 215	Homo sapiens (Human)	PR
Q8TBJ5	FEZF2	Fez family zinc finger protein 2	Homo sapiens (Human)	PR
Q96SR6	ZNF382	Zinc finger protein 382	Homo sapiens (Human)	PR
Q96IT1	ZNF496	Zinc finger protein 496	Homo sapiens (Human)	PR
Q96N95	ZNF396	Zinc finger protein 396	Homo sapiens (Human)	PR
Q9ULJ3	ZBTB21	Zinc finger and BTB domain-containing protein 21	Homo sapiens (Human)	PR
O75840	KLF7	Krueppel-like factor 7	Homo sapiens (Human)	PR
Q9H9D4	ZNF408	Zinc finger protein 408	Homo sapiens (Human)	PR
Q13127	REST	RE1-silencing transcription factor	Homo sapiens (Human)	PR
Q8IZM8	ZNF654	Zinc finger protein 654	Homo sapiens (Human)	PR
Q14526	HIC1	Hypermethylated in cancer 1 protein	Homo sapiens (Human)	PR
P17022	ZNF18	Zinc finger protein 18	Homo sapiens (Human)	PR
Q86XF7	ZNF575	Zinc finger protein 575	Homo sapiens (Human)	PR
Q06889	EGR3	Early growth response protein 3	Homo sapiens (Human)	PR
Q8NAM6	ZSCAN4	Zinc finger and SCAN domain-containing protein 4	Homo sapiens (Human)	PR
Q08ER8	ZNF543	Zinc finger protein 543	Homo sapiens (Human)	PR
P17029	ZKSCAN1	Zinc finger protein with KRAB and SCAN domains 1	Homo sapiens (Human)	PR
Q8N680	ZBTB2	Zinc finger and BTB domain-containing protein 2	Homo sapiens (Human)	PR
O95625	ZBTB11	Zinc finger and BTB domain-containing protein 11	Homo sapiens (Human)	PR
Q9NPC7	MYNN	Myoneurin	Homo sapiens (Human)	PR
Q96BV0	ZNF775	Zinc finger protein 775	Homo sapiens (Human)	PR
Q8NF99	ZNF397	Zinc finger protein 397	Homo sapiens (Human)	PR
Q63HK3	ZKSCAN2	Zinc finger protein with KRAB and SCAN domains 2	Homo sapiens (Human)	PR
Q5FWF6	ZNF789	Zinc finger protein 789	Homo sapiens (Human)	PR
Q15776	ZKSCAN8	Zinc finger protein with KRAB and SCAN domains 8	Homo sapiens (Human)	PR
Q53GI3	ZNF394	Zinc finger protein 394	Homo sapiens (Human)	PR
O95125	ZNF202	Zinc finger protein 202	Homo sapiens (Human)	PR
Q05516	ZBTB16	Zinc finger and BTB domain-containing protein 16	Homo sapiens (Human)	PR
Q9H116	GZF1	GDNF-inducible zinc finger protein 1	Homo sapiens (Human)	PR
Q8N0Y2	ZNF444	Zinc finger protein 444	Homo sapiens (Human)	PR
Q6P9G9	ZNF449	Zinc finger protein 449	Homo sapiens (Human)	PR
Q8IW36	ZNF695	Zinc finger protein 695	Homo sapiens (Human)	PR
Q5VTD9	GFI1B	Zinc finger protein Gfi-1b	Homo sapiens (Human)	PR
Q6PG37	ZNF790	Zinc finger protein 790	Homo sapiens (Human)	PR
Q9NQV6	PRDM10	PR domain zinc finger protein 10	Homo sapiens (Human)	PR
Q9Y2D9	ZNF652	Zinc finger protein 652	Homo sapiens (Human)	PR
Q5TC79	ZBTB37	Zinc finger and BTB domain-containing protein 37	Homo sapiens (Human)	PR
Q9Y4E5	ZNF451	E3 SUMO-protein ligase ZNF451	Homo sapiens (Human)	PR
Q8ND82	ZNF280C	Zinc finger protein 280C	Homo sapiens (Human)	PR
O43298	ZBTB43	Zinc finger and BTB domain-containing protein 43	Homo sapiens (Human)	PR
Q9Y330	ZBTB12	Zinc finger and BTB domain-containing protein 12	Homo sapiens (Human)	PR
Q13105	ZBTB17	Zinc finger and BTB domain-containing protein 17	Homo sapiens (Human)	PR
P51508	ZNF81	Zinc finger protein 81	Homo sapiens (Human)	PR
Q5JNZ3	ZNF311	Zinc finger protein 311	Homo sapiens (Human)	PR
Q9BRR0	ZKSCAN3	Zinc finger protein with KRAB and SCAN domains 3	Homo sapiens (Human)	PR
Q969J2	ZKSCAN4	Zinc finger protein with KRAB and SCAN domains 4	Homo sapiens (Human)	PR
P49910	ZNF165	Zinc finger protein 165	Homo sapiens (Human)	PR
Q9Y4X4	KLF12	Krueppel-like factor 12	Homo sapiens (Human)	PR
P10074	ZBTB48	Telomere zinc finger-associated protein	Homo sapiens (Human)	PR
P17010	ZFX	Zinc finger X-chromosomal protein	Homo sapiens (Human)	PR
Q6NSZ9	ZSCAN25	Zinc finger and SCAN domain-containing protein 25	Homo sapiens (Human)	PR
Q9Y2L8	ZKSCAN5	Zinc finger protein with KRAB and SCAN domains 5	Homo sapiens (Human)	PR
Q86UZ6	ZBTB46	Zinc finger and BTB domain-containing protein 46	Homo sapiens (Human)	PR
Q9NX65	ZSCAN32	Zinc finger and SCAN domain-containing protein 32	Homo sapiens (Human)	PR
O14771	ZNF213	Zinc finger protein 213	Homo sapiens (Human)	PR
Q8IWY8	ZSCAN29	Zinc finger and SCAN domain-containing protein 29	Homo sapiens (Human)	PR
Q8NCP5	ZBTB44	Zinc finger and BTB domain-containing protein 44	Homo sapiens (Human)	PR
P41182	BCL6	B-cell lymphoma 6 protein	Homo sapiens (Human)	PR
Q9NQX0	PRDM6	Putative histone-lysine N-methyltransferase PRDM6	Homo sapiens (Human)	PR
Q9BU19	ZNF692	Zinc finger protein 692	Homo sapiens (Human)	PR
Q08AG5	ZNF844	Zinc finger protein 844	Homo sapiens (Human)	PR
Q6R2W3	ZBED9	SCAN domain-containing protein 3	Homo sapiens (Human)	PR
P98182	ZNF200	Zinc finger protein 200	Homo sapiens (Human)	PR
Q9UK11	ZNF223	Zinc finger protein 223	Homo sapiens (Human)	PR
O15156	ZBTB7B	Zinc finger and BTB domain-containing protein 7B	Homo sapiens (Human)	PR
Q6ZMS7	ZNF783	Zinc finger protein 783	Homo sapiens (Human)	PR
P59923	ZNF445	Zinc finger protein 445	Homo sapiens (Human)	PR
Q8N859	ZNF713	Zinc finger protein 713	Homo sapiens (Human)	PR
Q99612	KLF6	Krueppel-like factor 6	Homo sapiens (Human)	PR
P52739	ZNF131	Zinc finger protein 131	Homo sapiens (Human)	PR
A6NGD5	ZSCAN5C	Zinc finger and SCAN domain-containing protein 5C	Homo sapiens (Human)	PR
Q05215	EGR4	Early growth response protein 4	Homo sapiens (Human)	PR
Q9Y2K1	ZBTB1	Zinc finger and BTB domain-containing protein 1	Homo sapiens (Human)	PR
A6NJL1	ZSCAN5B	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	PR
A1YPR0	ZBTB7C	Zinc finger and BTB domain-containing protein 7C	Homo sapiens (Human)	PR
Q9NWS9	ZNF446	Zinc finger protein 446	Homo sapiens (Human)	PR
P24278	ZBTB25	Zinc finger and BTB domain-containing protein 25	Homo sapiens (Human)	PR
Q96N38	ZNF714	Zinc finger protein 714	Homo sapiens (Human)	PR
Q86YH2	ZNF280B	Zinc finger protein 280B	Homo sapiens (Human)	PR
Q96N20	ZNF75A	Zinc finger protein 75A	Homo sapiens (Human)	PR
Q9H5H4	ZNF768	Zinc finger protein 768	Homo sapiens (Human)	PR
Q7Z398	ZNF550	Zinc finger protein 550	Homo sapiens (Human)	PR
Q8TD17	ZNF398	Zinc finger protein 398	Homo sapiens (Human)	PR
O08584	Klf6	Krueppel-like factor 6	Mus musculus (Mouse)	PR
Q61164	Ctcf	Transcriptional repressor CTCF	Mus musculus (Mouse)	PR
Q810A1	Znf18	Zinc finger protein 18	Mus musculus (Mouse)	PR
Q8BGS3	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Mus musculus (Mouse)	PR
Q00899	Yy1	Transcriptional repressor protein YY1	Mus musculus (Mouse)	PR
P41183	Bcl6	B-cell lymphoma 6 protein homolog	Mus musculus (Mouse)	PR
Q9DAI4	Zbtb43	Zinc finger and BTB domain-containing protein 43	Mus musculus (Mouse)	PR
O70237	Gfi1b	Zinc finger protein Gfi-1b	Mus musculus (Mouse)	PR
Q99KZ6	Znf639	Zinc finger protein 639	Mus musculus (Mouse)	PR
Q9Z1D9	Znf394	Zinc finger protein 394	Mus musculus (Mouse)	PR
Q9CXE0	Prdm5	PR domain zinc finger protein 5	Mus musculus (Mouse)	PR
P43300	Egr3	Early growth response protein 3	Mus musculus (Mouse)	PR
Q9DAU9	Znf654	Zinc finger protein 654	Mus musculus (Mouse)	PR
Q9R1Y5	Hic1	Hypermethylated in cancer 1 protein	Mus musculus (Mouse)	PR
Q8R0T2	Znf768	Zinc finger protein 768	Mus musculus (Mouse)	PR
Q9WVG7	Osr1	Protein odd-skipped-related 1	Mus musculus (Mouse)	PR
Q8BI73	Znf775	Zinc finger protein 775	Mus musculus (Mouse)	PR
Q8VCZ7	Zbtb7c	Zinc finger and BTB domain-containing protein 7C	Mus musculus (Mouse)	PR
Q91VN1	Znf24	Zinc finger protein 24	Mus musculus (Mouse)	PR
Q9DB38	Znf580	Zinc finger protein 580	Mus musculus (Mouse)	PR
A7KBS4	Zscan4d	Zinc finger and SCAN domain containing protein 4D	Mus musculus (Mouse)	PR
Q91VW9	Zkscan3	Zinc finger protein with KRAB and SCAN domains 3	Mus musculus (Mouse)	PR
P10925	Zfy1	Zinc finger Y-chromosomal protein 1	Mus musculus (Mouse)	PR
P08046	Egr1	Early growth response protein 1	Mus musculus (Mouse)	PR
Q3TTC2	Yy2	Transcription factor YY2	Mus musculus (Mouse)	PR
Q3UTQ7	Prdm10	PR domain zinc finger protein 10	Mus musculus (Mouse)	PR
Q6P3Y5	Znf280c	Zinc finger protein 280C	Mus musculus (Mouse)	PR
Q9ERU3	Znf22	Zinc finger protein 22	Mus musculus (Mouse)	PR
Q8VIG1	Rest	RE1-silencing transcription factor	Mus musculus (Mouse)	PR
Q9Z1D8	Zkscan5	Zinc finger protein with KRAB and SCAN domains 5	Mus musculus (Mouse)	PR
Q8BID6	Zbtb46	Zinc finger and BTB domain-containing protein 46	Mus musculus (Mouse)	PR
P17012	Zfx	Zinc finger X-chromosomal protein	Mus musculus (Mouse)	PR
Q9WUK6	Zbtb18	Zinc finger and BTB domain-containing protein 18	Mus musculus (Mouse)	PR
O35738	Klf12	Krueppel-like factor 12	Mus musculus (Mouse)	PR
B2RXC5	Znf382	Zinc finger protein 382	Mus musculus (Mouse)	PR
O08900	Ikzf3	Zinc finger protein Aiolos	Mus musculus (Mouse)	PR
Q5DU09	Znf652	Zinc finger protein 652	Mus musculus (Mouse)	PR
Q5RJ54	Zscan26	Zinc finger and SCAN domain-containing protein 26	Mus musculus (Mouse)	PR
Q8BLM0	Klf8	Krueppel-like factor 8	Mus musculus (Mouse)	PR
Q99JB0	Klf7	Krueppel-like factor 7	Mus musculus (Mouse)	PR
Q8R0A2	Zbtb44	Zinc finger and BTB domain-containing protein 44	Mus musculus (Mouse)	PR
P20662	Zfy2	Zinc finger Y-chromosomal protein 2	Mus musculus (Mouse)	PR
Q80VJ6	Zscan4c	Zinc finger and SCAN domain containing protein 4C	Mus musculus (Mouse)	PR
Q3URS2	Zscan4f	Zinc finger and SCAN domain containing protein 4F	Mus musculus (Mouse)	PR
Q60980	Klf3	Krueppel-like factor 3	Mus musculus (Mouse)	PR
Q8K3J5	Znf131	Zinc finger protein 131	Mus musculus (Mouse)	PR
Q9Z2K3	Znf394	Zinc finger protein 394	Rattus norvegicus (Rat)	PR
Q642B9	Znf18	Zinc finger protein 18	Rattus norvegicus (Rat)	PR
B0K011	Osr1	Protein odd-skipped-related 1	Rattus norvegicus (Rat)	PR
D3ZUU2	Gzf1	GDNF-inducible zinc finger protein 1	Rattus norvegicus (Rat)	PR
B1WBU4	Zbtb8a	Zinc finger and BTB domain-containing protein 8A	Rattus norvegicus (Rat)	PR
Q7TNK3	Znf24	Zinc finger protein 24	Rattus norvegicus (Rat)	PR
O35819	Klf6	Krueppel-like factor 6	Rattus norvegicus (Rat)	PR
Q9R1D1	Ctcf	Transcriptional repressor CTCF	Rattus norvegicus (Rat)	PR
P43301	Egr3	Early growth response protein 3	Rattus norvegicus (Rat)	PR
P08154	Egr1	Early growth response protein 1	Rattus norvegicus (Rat)	PR
A0JPL0	Znf382	Zinc finger protein 382	Rattus norvegicus (Rat)	PR
Q4KLI1	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Rattus norvegicus (Rat)	PR
A1L1J6	Znf652	Zinc finger protein 652	Rattus norvegicus (Rat)	PR
Q9SHD0	ZAT4	Zinc finger protein ZAT4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q0P4X6	zbtb44	Zinc finger and BTB domain-containing protein 44	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
A4II20	egr1	Early growth response protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q6P882	zbtb8a.2	Zinc finger and BTB domain-containing protein 8A.2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q567C6	znf367	Zinc finger protein 367	Danio rerio (Zebrafish) (Brachydanio rerio)	PR
A7Y7X5	znf711	Zinc finger protein 711	Danio rerio (Zebrafish) (Brachydanio rerio)	PR

10	20	30	40	50	60
MPQQLLITLP	TEASTWVKLQ	HPKKAVEGAP	LWEDVTKMFE	GEALLSQDAE	DVKTQRESLE
70	80	90	100	110	120
DEVTPGLPTA	ESQELLTFKD	ISIDFTQEEW	GQLAPAHQNL	YREVMLENYS	NLVSVGYQLS
130	140	150	160	170	180
KPSVISQLEK	GEEPWMAEKE	GPGDPSSDLK	SKIETIESTA	KSTISQERLY	HGIMMESFMR
190	200	210	220	230	240
DDIIYSTLRK	VSTYDDVLER	HQETCMRDVR	QAILTHKKRV	QETNKFGENI	IVHSNVIIEQ
250	260	270	280	290	300
RHHKYDTPTK	RNTYKLDLIN	HPTSYIRTKT	YECNICEKIF	KQPIHLTEHM	RIHTGEKPFR
310	320	330	340	350	360
CKECGRAFSQ	SASLSTHQRI	HTGEKPFECE	ECGKAFRHRS	SLNQHHRTHT	GEKPYVCDKC
370	380	390	400	410	420
QKAFSQNISL	VQHLRTHSGE	KPFTCNECGK	TFRQIRHLSE	HIRIHTGEKP	YACTACCKTF
430	440	450	460	470	480
SHRAYLTHHQ	RIHTGERPYK	CKECGKAFRQ	RIHLSNHKTV	HTGVKAYECN	RCGKAYRHDS
490	500	510	520
SFKKHQRHHT	GEKPYECNEC	GKAFSYNSSL	SRHHEIHRRN	AFRNKV