Q2TBP1
Gene name |
DDX25 |
Protein name |
ATP-dependent RNA helicase DDX25 |
Names |
DEAD box protein 25 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:508962 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2TBP1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2TBP1-F1 | Predicted | AlphaFoldDB |
No variants for Q2TBP1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2TBP1 | |||||
No associated diseases with Q2TBP1
4 regional properties for Q2TBP1
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatoid body | A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182). |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA export from nucleus | The directed movement of mRNA from the nucleus to the cytoplasm. |
| regulation of translation | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. |
| spermatid development | The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2NL22 | EIF4A3 | Eukaryotic initiation factor 4A-III | Bos taurus (Bovine) | PR |
| Q5W5U4 | DDX4 | Probable ATP-dependent RNA helicase DDX4 | Bos taurus (Bovine) | SS |
| Q3ZBV2 | DDX19A | ATP-dependent RNA helicase DDX19A | Bos taurus (Bovine) | SS |
| Q3SZ65 | EIF4A2 | Eukaryotic initiation factor 4A-II | Bos taurus (Bovine) | PR |
| Q3T147 | DDX39B | Spliceosome RNA helicase DDX39B | Bos taurus (Bovine) | PR |
| Q0IIK5 | DDX1 | ATP-dependent RNA helicase DDX1 | Bos taurus (Bovine) | PR |
| Q9UMR2 | DDX19B | ATP-dependent RNA helicase DDX19B | Homo sapiens (Human) | PR |
| Q9NUU7 | DDX19A | ATP-dependent RNA helicase DDX19A | Homo sapiens (Human) | PR |
| Q9UHL0 | DDX25 | ATP-dependent RNA helicase DDX25 | Homo sapiens (Human) | PR |
| Q61655 | Ddx19a | ATP-dependent RNA helicase DDX19A | Mus musculus (Mouse) | SS |
| Q9QY15 | Ddx25 | ATP-dependent RNA helicase DDX25 | Mus musculus (Mouse) | PR |
| Q10RI7 | Os03g0158200 | DEAD-box ATP-dependent RNA helicase 38 | Oryza sativa subsp japonica (Rice) | PR |
| Q93ZG7 | RH38 | DEAD-box ATP-dependent RNA helicase 38 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASLLWGGDA | GAAESERLNG | HFSNLIHPQN | HLLGIKSATI | PNIDGSVNRI | EEDDEDDVVD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LAANSLLNKL | IRQSLVESSH | RVEVLQKDPS | SPLYSVKTFE | ELRLKEELLK | GIYAMGFNRP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SKIQEMALPM | MLAHPPQNLI | AQSQSGTGKT | AAFVLAMLSR | VNALKLFPQC | LCLAPTYELA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LQTGRVVERM | GKFCVDVQVM | YAIRGNRIPR | GTDVTKQIVI | GTPGTVLDWC | FKRKLIDLTK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IRVFVLDEAD | VMIDTQGFED | QSIRIQRALP | SECQMLLFSA | TFEDSVWQFA | ERIIPDPNVI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KLRKEELTLN | NIRQYYVLCG | NRKDKYQALC | NIYGGITIGQ | AIIFCQTRRN | AKWLTVEMMQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DGHQVSLLSG | ELTVDQRASI | IQRFRDGKEK | VLITTNVCAR | GIDVKQVTIV | VNFDLPVNQA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EEPDYETYLH | RIGRTGRFGK | KGLAFNMIEV | DKLPLLMKIQ | DHFNSSIKQL | DPEDMDEIEK |
| IEY |