Q2TA29
PR
Gene name |
RAB11A |
Protein name |
Ras-related protein Rab-11A |
Names |
Rab-11 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:534708 |
EC number |
3.6.5.2: Acting on GTP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2TA29
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2TA29-F1 | Predicted | AlphaFoldDB |
No variants for Q2TA29
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2TA29 | |||||
No associated diseases with Q2TA29
1 regional properties for Q2TA29
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 10 - 168 | IPR005225 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.5.2 | Acting on GTP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cleavage furrow | The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm. |
| phagocytic vesicle | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. |
| recycling endosome | An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane. |
| recycling endosome membrane | The lipid bilayer surrounding a recycling endosome. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein activity | A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP). |
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| melanosome transport | The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| neuron projection development | The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). |
| protein localization to plasma membrane | A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2TBH7 | RAB4A | Ras-related protein Rab-4A | Bos taurus (Bovine) | PR |
| Q3MHP2 | RAB11B | Ras-related protein Rab-11B | Bos taurus (Bovine) | PR |
| Q5ZJN2 | RAB11A | Ras-related protein Rab-11A | Gallus gallus (Chicken) | PR |
| P62490 | RAB11A | Ras-related protein Rab-11A | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| Q15907 | RAB11B | Ras-related protein Rab-11B | Homo sapiens (Human) | PR |
| P62491 | RAB11A | Ras-related protein Rab-11A | Homo sapiens (Human) | PR |
| P46638 | Rab11b | Ras-related protein Rab-11B | Mus musculus (Mouse) | PR |
| P62492 | Rab11a | Ras-related protein Rab-11A | Mus musculus (Mouse) | PR |
| Q52NJ1 | RAB11A | Ras-related protein Rab-11A | Sus scrofa (Pig) | PR |
| O35509 | Rab11b | Ras-related protein Rab-11B | Rattus norvegicus (Rat) | PR |
| P62494 | Rab11a | Ras-related protein Rab-11A | Rattus norvegicus (Rat) | PR |
| Q9LNK1 | RABA3 | Ras-related protein RABA3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LH50 | RABA4D | Ras-related protein RABA4d | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FE79 | RABA4C | Ras-related protein RABA4c | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O04486 | RABA2A | Ras-related protein RABA2a | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49513 | RABA1E | Ras-related protein RABA1e | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNW1 | RABA2B | Ras-related protein RABA2b | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGTRDDEYDY | LFKVVLIGDS | GVGKSNLLSR | FTRNEFNLES | KSTIGVEFAT | RSIQVDGKTI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KAQIWDTAGQ | ERYRAITSAY | YRGAVGALLV | YDIAKHLTYE | NVERWLKELR | DHADSNIVIM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LVGNKSDLRH | LRAVPTDEAR | AFAEKNGLSF | IETSALDYTN | VEAAFQTILT | EIYRIVSQKQ |
| 190 | 200 | 210 | |||
| MSDRRENDMS | PSNNVVPIHV | PPTTENKPKV | QCCQNI |