Q2QY53

PR
Gene name
CIPK32 (Os12g0132200, LOC_Os12g03810)
Protein name
CBL-interacting protein kinase 32
Names
OsCIPK32
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4351419
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

272-379 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

153-178 (Activation loop from InterPro)

Target domain

13-268 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q2QY53

Entry ID Method Resolution Chain Position Source
AF-Q2QY53-F1 Predicted AlphaFoldDB

No variants for Q2QY53

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2QY53

No associated diseases with Q2QY53

No regional properties for Q2QY53

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q2QY53

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
protein phosphorylation The process of introducing a phosphate group on to a protein.

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P06782 SNF1 Carbon catabolite-derepressing protein kinase Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) EV
O60285 NUAK1 NUAK family SNF1-like kinase 1 Homo sapiens (Human) PR
O14757 CHEK1 Serine/threonine-protein kinase Chk1 Homo sapiens (Human) EV
Q9NRH2 SNRK SNF-related serine/threonine-protein kinase Homo sapiens (Human) SS
P57059 SIK1 Serine/threonine-protein kinase SIK1 Homo sapiens (Human) PR
P54646 PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens (Human) EV
Q13131 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 Homo sapiens (Human) EV
Q641K5 Nuak1 NUAK family SNF1-like kinase 1 Mus musculus (Mouse) PR
Q61846 Melk Maternal embryonic leucine zipper kinase Mus musculus (Mouse) PR
Q8C0X8 Sperm motility kinase X Mus musculus (Mouse) PR
A0AUV4 Gm7168 Sperm motility kinase Y Mus musculus (Mouse) PR
A2KF29 Smoktcr Sperm motility kinase Tcr mutant form Mus musculus (Mouse) PR
Q8C0N0 Gm4922 Sperm motility kinase Z Mus musculus (Mouse) PR
Q8BRK8 Prkaa2 5'-AMP-activated protein kinase catalytic subunit alpha-2 Mus musculus (Mouse) SS
Q5EG47 Prkaa1 5'-AMP-activated protein kinase catalytic subunit alpha-1 Mus musculus (Mouse) SS
Q28948 PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 Sus scrofa (Pig) SS
Q09136 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 Sus scrofa (Pig) SS
Q09137 Prkaa2 5'-AMP-activated protein kinase catalytic subunit alpha-2 Rattus norvegicus (Rat) EV
P54645 Prkaa1 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus (Rat) EV
Q8LIG4 CIPK3 CBL-interacting protein kinase 3 Oryza sativa subsp japonica (Rice) PR
Q2RAX3 CIPK33 CBL-interacting protein kinase 33 Oryza sativa subsp japonica (Rice) PR
Q6ZLP5 CIPK23 CBL-interacting protein kinase 23 Oryza sativa subsp japonica (Rice) PR
Q5N942 SAPK4 Serine/threonine-protein kinase SAPK4 Oryza sativa subsp japonica (Rice) PR
Q7XQP4 SAPK7 Serine/threonine-protein kinase SAPK7 Oryza sativa subsp japonica (Rice) PR
Q75LR7 SAPK1 Serine/threonine-protein kinase SAPK1 Oryza sativa subsp japonica (Rice) PR
Q0D4J7 SAPK2 Serine/threonine-protein kinase SAPK2 Oryza sativa subsp japonica (Rice) PR
Q7Y0B9 SAPK8 Serine/threonine-protein kinase SAPK8 Oryza sativa subsp japonica (Rice) PR
Q75V57 SAPK9 Serine/threonine-protein kinase SAPK9 Oryza sativa subsp japonica (Rice) PR
Q75H77 SAPK10 Serine/threonine-protein kinase SAPK10 Oryza sativa subsp japonica (Rice) PR
P0C5D6 SAPK3 Serine/threonine-protein kinase SAPK3 Oryza sativa subsp japonica (Rice) PR
Q852Q1 OSK4 Serine/threonine protein kinase OSK4 Oryza sativa subsp. japonica (Rice) SS
Q852Q2 OSK1 Serine/threonine protein kinase OSK1 Oryza sativa subsp. japonica (Rice) SS
Q21017 kin-29 Serine/threonine-protein kinase kin-29 Caenorhabditis elegans SS
P45894 aak-1 5'-AMP-activated protein kinase catalytic subunit alpha-1 Caenorhabditis elegans SS
Q95ZQ4 aak-2 5'-AMP-activated protein kinase catalytic subunit alpha-2 Caenorhabditis elegans SS
Q2V452 CIPK3 CBL-interacting serine/threonine-protein kinase 3 Arabidopsis thaliana (Mouse-ear cress) SS
10 20 30 40 50 60
MSTTKVKRRV GKYELGRTIG EGTFAKVKFA RDTETGDPVA IKILDKEKVL KHKMVEQIKR
70 80 90 100 110 120
EISTMKLIKH PNVVRIYEVM GSKTKIYIVL EYVTGGELFD TIVNHGRMRE DEARRYFQQL
130 140 150 160 170 180
INAVDYCHSR GVYHRDLKPE NLLLDSYGNL KVSDFGLSAL SQQIKDDGLL HTTCGTPNYV
190 200 210 220 230 240
APEVLEDQGY DGAMADLWSC GVILFVLLAG YLPFEDSNLM TLYKKISNAE FTFPPWTSFP
250 260 270 280 290 300
AKRLLTRILD PNPMTRVTIP EILEDEWFKK GYKRPEFDEK YDTTLDDVYA VFNDSEEHHV
310 320 330 340 350 360
TEKKEEPEAL NAFELISMSA GLNLGNLFDS EQEFKRETRF TSKCPPKEIV RKIEEAAKPL
370 380 390 400 410 420
GFDVQKKNYK LRLEKVKAGR KGNLNVATEI LQVAPSLHMV EVRKAKGDTL EFHKFYKNLS
430
RTLKDVVWKS DDLQNQLS