Q2HJI8
Gene name |
RAB8B |
Protein name |
Ras-related protein Rab-8B |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:614242 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2HJI8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2HJI8-F1 | Predicted | AlphaFoldDB |
No variants for Q2HJI8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2HJI8 | |||||
No associated diseases with Q2HJI8
3 regional properties for Q2HJI8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | 14-3-3 protein, conserved site | 45 - 55 | IPR023409-1 |
| conserved_site | 14-3-3 protein, conserved site | 217 - 236 | IPR023409-2 |
| domain | 14-3-3 domain | 5 - 248 | IPR023410 |
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| phagocytic vesicle | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. |
| phagocytic vesicle membrane | The lipid bilayer surrounding a phagocytic vesicle. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GDP binding | Binding to GDP, guanosine 5'-diphosphate. |
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
26 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A4FV54 | RAB8A | Ras-related protein Rab-8A | Bos taurus (Bovine) | PR |
| Q1RMR4 | RAB15 | Ras-related protein Rab-15 | Bos taurus (Bovine) | PR |
| Q5F470 | RAB8A | Ras-related protein Rab-8A | Gallus gallus (Chicken) | PR |
| P0C0E4 | RAB40AL | Ras-related protein Rab-40A-like | Homo sapiens (Human) | PR |
| P61006 | RAB8A | Ras-related protein Rab-8A | Homo sapiens (Human) | PR |
| Q6IQ22 | RAB12 | Ras-related protein Rab-12 | Homo sapiens (Human) | PR |
| Q8WXH6 | RAB40A | Ras-related protein Rab-40A | Homo sapiens (Human) | PR |
| Q96S21 | RAB40C | Ras-related protein Rab-40C | Homo sapiens (Human) | PR |
| Q12829 | RAB40B | Ras-related protein Rab-40B | Homo sapiens (Human) | PR |
| Q92930 | RAB8B | Ras-related protein Rab-8B | Homo sapiens (Human) | PR |
| P55258 | Rab8a | Ras-related protein Rab-8A | Mus musculus (Mouse) | PR |
| Q8K386 | Rab15 | Ras-related protein Rab-15 | Mus musculus (Mouse) | PR |
| P35283 | Rab12 | Ras-related protein Rab-12 | Mus musculus (Mouse) | PR |
| Q9DD03 | Rab13 | Ras-related protein Rab-13 | Mus musculus (Mouse) | PR |
| Q8CB87 | Rab44 | Ras-related protein Rab-44 | Mus musculus (Mouse) | PR |
| Q8VHP8 | Rab40b | Ras-related protein Rab-40B | Mus musculus (Mouse) | PR |
| Q8VHQ4 | Rab40c | Ras-related protein Rab-40C | Mus musculus (Mouse) | PR |
| P61028 | Rab8b | Ras-related protein Rab-8B | Mus musculus (Mouse) | PR |
| P35289 | Rab15 | Ras-related protein Rab-15 | Rattus norvegicus (Rat) | PR |
| P35280 | Rab8a | Ras-related protein Rab-8A | Rattus norvegicus (Rat) | PR |
| P35284 | Rab12 | Ras-related protein Rab-12 | Rattus norvegicus (Rat) | PR |
| P35281 | Rab10 | Ras-related protein Rab-10 | Rattus norvegicus (Rat) | PR |
| P70550 | Rab8b | Ras-related protein Rab-8B | Rattus norvegicus (Rat) | PR |
| O24466 | RABE1A | Ras-related protein RABE1a | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SF91 | RABE1E | Ras-related protein RABE1e | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZD4 | RABE1D | Ras-related protein RABE1d | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKTYDYLFK | LLLIGDSGVG | KTCLLFRFSE | DAFNTTFIST | IGIDFKIRTI | ELDGKKIKLQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IWDTAGQERF | RTITTAYYRG | AMGIMLVYDI | TNEKSFDNIK | NWIRNIEEHA | SSDVERMILG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKCDMNDKRQ | VSKERGEKLA | IDYGIKFLEA | SAKSSMNVEE | AFFTLARDIM | TKLNRKMNDS |
| 190 | 200 | ||||
| NSSGAGGPVK | ITENRSKKTS | FFRCLLL |