Q27521

PR
Gene name
nhr-16 (T12C9.6)
Protein name
Nuclear hormone receptor family member nhr-16
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_T12C9.6
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

62-156 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q27521

Entry ID Method Resolution Chain Position Source
AF-Q27521-F1 Predicted AlphaFoldDB

No variants for Q27521

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q27521

No associated diseases with Q27521

2 regional properties for Q27521

Type Name Position InterPro Accession
domain Nuclear hormone receptor, ligand-binding domain 115 - 387 IPR000536
domain Zinc finger, nuclear hormone receptor-type 11 - 86 IPR001628

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O18141 nhr-79 Nuclear hormone receptor family member nhr-79 Caenorhabditis elegans PR
10 20 30 40 50 60
MGGPRFKDKV FLKCAICQES AEGFHFGAEA CRACAAFFRR TVSNRKTYSC QGNNDCDVTI
70 80 90 100 110 120
NIRCMCRACR YIKCIEVGMN PAGVQQRLPP SKTLVEVSMD LPTVSNPSIL SFPSPPSSLM
130 140 150 160 170 180
LHIPSSYSNQ MPILDKMRKS YETLCNARKT LHRKDGANIF QDNVPKPVTY KKAIDQGMKD
190 200 210 220 230 240
VKLTSDWVSW CFEDFKNLSI DQKKILFHNA YTPYFMMEGG FLSHIRNTPE HLVMPSGDYI
250 260 270 280 290 300
DTLDLNSFYN CSESDRQISS KEIDRLFKPS NDRFIKSVTL PMMSLQLDIF EFFVLFTLLL
310 320 330 340 350 360
WDTGLIEISE ECIEIGTKVK TQVLKELDFY MRNVKKVEEP LVRTANIVNL LPAVQKGVRR
370 380
IQDDLEVTKV FDLYTASDEF YNLMSGRF