Q20365
Gene name |
rab-33 (F43D9.2) |
Protein name |
Ras-related protein Rab-33 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_F43D9.2 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q20365
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q20365-F1 | Predicted | AlphaFoldDB |
No variants for Q20365
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q20365 | |||||
No associated diseases with Q20365
1 regional properties for Q20365
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 99 - 255 | IPR005225 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| Rab protein signal transduction | The series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. |
14 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3ZC27 | RAB19 | Ras-related protein Rab-19 | Bos taurus (Bovine) | PR |
| Q5ZHV1 | RAB33B | Ras-related protein Rab-33B | Gallus gallus (Chicken) | PR |
| A4D1S5 | RAB19 | Ras-related protein Rab-19 | Homo sapiens (Human) | PR |
| Q9H082 | RAB33B | Ras-related protein Rab-33B | Homo sapiens (Human) | PR |
| P35294 | Rab19 | Ras-related protein Rab-19 | Mus musculus (Mouse) | PR |
| O35963 | Rab33b | Ras-related protein Rab-33B | Mus musculus (Mouse) | PR |
| Q5M7U5 | Rab19 | Ras-related protein Rab-19 | Rattus norvegicus (Rat) | PR |
| P25766 | RGP1 | Ras-related protein RGP1 | Oryza sativa subsp japonica (Rice) | PR |
| Q9LNK1 | RABA3 | Ras-related protein RABA3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O04486 | RABA2A | Ras-related protein RABA2a | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNW1 | RABA2B | Ras-related protein RABA2b | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LH50 | RABA4D | Ras-related protein RABA4d | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FE79 | RABA4C | Ras-related protein RABA4c | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SJZ5 | RABA4E | Putative Ras-related protein RABA4e | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEHHVNIPA | PQFSTYATVI | DPPKHVTATH | PDELTTASHP | QPTHPSAPQD | PSPAVPSTPV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RVPYPTAPPP | IPPAPEAVTA | GPKKMALAPS | STKTYKQKRT | FKVIIVGNAA | VGKTCLSFRF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CCGRFPEHTE | ATIGVDFRER | SCVIENELLR | VQLWDTAGQE | RYRQSIVAHY | YRNVNAVVFV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YDVTCRESFN | DLALWIKECE | KHGLVGDSEV | PRILIGNKCD | VECTNRVSTD | EAQMFADRNN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MALFETSAKL | ASEADHVESI | FLTLLHKLQQ | SKPMHVQSQD | ERHQKEQERL | ILKANETENV |
| EEEGFCC |