Q1PFD1
Gene name |
BLH11 (At1g75430, F1B16.4) |
Protein name |
BEL1-like homeodomain protein 11 |
Names |
BEL1-like protein 11 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G75430 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q1PFD1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q1PFD1-F1 | Predicted | AlphaFoldDB |
16 variants for Q1PFD1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13812449 | 3 | D>G | No | 1000Genomes | |
| ENSVATH13812448 | 5 | R>G | No | 1000Genomes | |
| ENSVATH00143790 | 23 | A>T | No | 1000Genomes | |
| tmp_1_28309442_C_T | 26 | V>M | No | 1000Genomes | |
| ENSVATH14481189 | 37 | G>D | No | 1000Genomes | |
| tmp_1_28309357_G_C | 54 | P>R | No | 1000Genomes | |
| tmp_1_28309265_T_C | 85 | I>V | No | 1000Genomes | |
| ENSVATH01538688 | 93 | L>R | No | 1000Genomes | |
| ENSVATH13812442 | 110 | L>Q | No | 1000Genomes | |
| tmp_1_28308804_C_T | 128 | V>M | No | 1000Genomes | |
| ENSVATH05149137 | 154 | S>F | No | 1000Genomes | |
| ENSVATH05149136 | 161 | I>S | No | 1000Genomes | |
| ENSVATH13812441 | 166 | V>I | No | 1000Genomes | |
| ENSVATH05149135 | 192 | L>F | No | 1000Genomes | |
| tmp_1_28308355_A_T | 245 | S>T | No | 1000Genomes | |
| tmp_1_28308227_G_C | 256 | A>G | No | 1000Genomes |
No associated diseases with Q1PFD1
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8MIB7 | TGIF2LX | Homeobox protein TGIF2LX | Pan troglodytes (Chimpanzee) | PR |
| Q8IUE1 | TGIF2LX | Homeobox protein TGIF2LX | Homo sapiens (Human) | PR |
| P40424 | PBX1 | Pre-B-cell leukemia transcription factor 1 | Homo sapiens (Human) | PR |
| P40425 | PBX2 | Pre-B-cell leukemia transcription factor 2 | Homo sapiens (Human) | PR |
| O00470 | MEIS1 | Homeobox protein Meis1 | Homo sapiens (Human) | SS |
| Q99687 | MEIS3 | Homeobox protein Meis3 | Homo sapiens (Human) | SS |
| O14770 | MEIS2 | Homeobox protein Meis2 | Homo sapiens (Human) | EV |
| Q8IUE0 | TGIF2LY | Homeobox protein TGIF2LY | Homo sapiens (Human) | PR |
| A8K0S8 | MEIS3P2 | Putative homeobox protein Meis3-like 2 | Homo sapiens (Human) | PR |
| A6NDR6 | MEIS3P1 | Putative homeobox protein Meis3-like 1 | Homo sapiens (Human) | PR |
| O35984 | Pbx2 | Pre-B-cell leukemia transcription factor 2 | Mus musculus (Mouse) | PR |
| P97368 | Meis3 | Homeobox protein Meis3 | Mus musculus (Mouse) | PR |
| P97367 | Meis2 | Homeobox protein Meis2 | Mus musculus (Mouse) | SS |
| Q75LX7 | OSH10 | Homeobox protein knotted-1-like 4 | Oryza sativa subsp japonica (Rice) | PR |
| Q75LX9 | Os03g0673500 | Putative homeobox protein knotted-1-like 5 | Oryza sativa subsp japonica (Rice) | PR |
| Q19503 | ceh-40 | Homeobox protein ceh-40 | Caenorhabditis elegans | PR |
| Q9SIW1 | BLH7 | BEL1-like homeodomain protein 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEDFRVRHEC | SSLRGTLLDS | RYAKAVQCLV | EEVIDIGGRE | VELCNNILIN | QLFPGRRRPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FALSSEIKSE | LCSSGFMSLP | ENHEIHIKIT | KLLSLLQQVE | ERFEQYCNQL | EQVISSFEEI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AGEGSSKVYT | GLALQAMTRH | FGSLEEAIIS | QLNSVRRRFI | ISHQDVPKII | SSGLSQLSLF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DGNTTSSSLQ | RLGLVQGPQR | HAWKPIRGLP | ETSVAILRAW | LFQHFLHPYP | NEAEKLVLAS |
| 250 | 260 | 270 | 280 | ||
| QTGLSKNQVS | NWFINARVRL | WKPMIEEMYR | EEFGDSLDES | MQREANDDSN |