Q1LZ87

PR
Gene name
ZNF397
Protein name
Zinc finger protein 397
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:506448
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

101-306 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1LZ87

Entry ID Method Resolution Chain Position Source
AF-Q1LZ87-F1 Predicted AlphaFoldDB

No variants for Q1LZ87

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1LZ87

No associated diseases with Q1LZ87

10 regional properties for Q1LZ87

Type Name Position InterPro Accession
domain SCAN domain 46 - 158 IPR003309
domain Zinc finger C2H2-type 285 - 312 IPR013087-1
domain Zinc finger C2H2-type 313 - 340 IPR013087-2
domain Zinc finger C2H2-type 341 - 368 IPR013087-3
domain Zinc finger C2H2-type 369 - 396 IPR013087-4
domain Zinc finger C2H2-type 397 - 424 IPR013087-5
domain Zinc finger C2H2-type 425 - 452 IPR013087-6
domain Zinc finger C2H2-type 453 - 480 IPR013087-7
domain Zinc finger C2H2-type 481 - 508 IPR013087-8
domain Zinc finger C2H2-type 509 - 534 IPR013087-9

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
metal ion binding Binding to a metal ion.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6QNZ0 ZSCAN26 Zinc finger and SCAN domain-containing protein 26 Bos taurus (Bovine) PR
Q8NF99 ZNF397 Zinc finger protein 397 Homo sapiens (Human) PR
10 20 30 40 50 60
MAVESRAVST PVPQNSQEQE LILVKVEESR SWGQKLKQSG SARSCQELFR QQFRKFCYQE
70 80 90 100 110 120
TPGPREALGR LQELCYQWLR PELHTKEQIL ELLVLEQFLS ILPEELQIWV QQHSPKNGEE
130 140 150 160 170 180
AVTLLEDLER EFDDPGQQVP ATPQGPPMPW KDLTCLGAAQ EFTHIQRQPL KKQLKPWEPC
190 200 210 220 230 240
LPPKSGCENN ESAIKKDISG EKSQRLSQEP SFGGFSEHKS SLEWQQGSAP GETLRRSPSQ
250 260 270 280 290 300
RASFSPVIFT HKLLANRDHP EPQRNLILST NSVTYQKVPT EERPYRCDIC GHSFKQHSSL
310 320 330 340 350 360
TQHQRIHTGE KPYKCNQCGK AFSLRSYLII HQRIHSGEKA YECSECGKAF NQSSALIRHR
370 380 390 400 410 420
KIHTGEKACK CNECGKAFSQ SSYLIIHQRI HTGEKPYECN ECGKTFSQSS KLIRHQRIHT
430 440 450 460 470 480
GERPYECNEC GKAFRQSSEL ITHQRIHSGE KPYECNECGK AFSLSSNLIR HQRIHSGEEP
490 500 510 520 530
YQCNECGKTF KRSSALVQHQ RIHSGEEAYI CSECGKAFRH RSVLTRHQRV HTVK