Q16980
Gene name |
|
Protein name |
Twitchin-like protein |
Names |
|
Species |
Aplysia californica (California sea hare) |
KEGG Pathway |
|
EC number |
|
Protein Class |
SERINE/THREONINE-PROTEIN KINASE 17 (PTHR24342) |
Descriptions
The FcsRI-mediated calcium signal pathway is not affected by DHS but shows an inhibition when subjected to EGTA treatment, impacting the activation and signaling pathway.
Autoinhibitory domains (AIDs)
Target domain |
47-302 (Protein kinase domain) |
Relief mechanism |
Partner binding |
Assay |
Structural analysis |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q16980
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1KOB | X-ray | 230 A | A/B | 5-376 | PDB |
| AF-Q16980-F1 | Predicted | AlphaFoldDB |
No variants for Q16980
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q16980 | |||||
No associated diseases with Q16980
Functions
| Description | ||
|---|---|---|
| EC Number | ||
| Subcellular Localization |
|
|
| PANTHER Family | PTHR24342 | SERINE/THREONINE-PROTEIN KINASE 17 |
| PANTHER Subfamily | PTHR24342:SF15 | DEATH-ASSOCIATED PROTEIN KINASE 2 |
| PANTHER Protein Class |
non-receptor serine/threonine protein kinase
protein modifying enzyme |
|
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein kinase activity | Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| IKLLGRKVRG | KHDGPKINDY | DKFYEDIWKK | YVPQPVEVKQ | GSCYDYYDIL | EELGSGAFGV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VHRCVEKATG | RVFEAKFINT | PYPLDKYTVK | NEISIMNQLH | HPKLINLHDA | FEDKYDMVLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LEFLSGGELF | DRIAAEDYKM | SEAEVINYMR | QACEGLKHMH | EHSIVHLDIK | PENIMCETKK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ASSVKIIDFG | LATKLNPDEI | VKVTTATAEF | AAPEIVDREP | VGFYTDMWAI | GVLGYVLLSG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSPFAGEDDL | ETLQNVKRCD | WEFDEDAFSS | VSPEAKDFIK | NLLQKEPRKR | LTVHDALEHP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WLKGDHSNLT | SRIPSSRYNK | IRQKIKEKYA | DWPAPQPAIG | RIANFSSLRK | HRPQEYQIYD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SYFDRKEAVP | RFVRRPRNQI | TADESAKFDC | KIIAASPPIV | TWYKDDGLLG | QSYKHMHKYH |
| 430 | 440 | 450 | |||
| GSEYELKISR | IKMDDKGAAR | EKSIRTKSKV | D |