Q15776
PR
Gene name |
ZKSCAN8 (ZNF192) |
Protein name |
Zinc finger protein with KRAB and SCAN domains 8 |
Names |
LD5-1, Zinc finger protein 192 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:7745 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q15776
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q15776-F1 | Predicted | AlphaFoldDB |
414 variants for Q15776
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs780725960 CA3681720 |
2 | A>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 4 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3681721 rs745845523 |
8 | P>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA3681722 rs769759921 |
8 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA362904151 rs1374454722 |
11 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA3681725 rs768510722 |
13 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1003762006 CA362904254 |
14 | P>L | No |
ClinGen gnomAD |
|
|
rs1003762006 CA135805445 |
14 | P>R | No |
ClinGen gnomAD |
|
|
CA3681726 rs774732868 |
15 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs762083747 CA3681727 |
16 | Q>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 16 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767534634 CA3681728 |
17 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362904428 rs773319293 |
18 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA3681729 rs773319293 |
18 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA362904507 rs1275669072 |
20 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA3681730 rs377359410 |
21 | D>E | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1035200430 CA135805477 |
22 | L>I | No |
ClinGen Ensembl |
|
|
rs766902901 CA3681731 |
22 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs754288086 CA3681732 |
23 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs141619075 CA3681734 |
24 | I>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs141619075 CA3681735 |
24 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs780627318 CA3681737 |
25 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs780627318 CA362904677 |
25 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs1397791708 CA362904707 |
26 | K>N | No |
ClinGen TOPMed |
|
|
CA3681738 rs745382215 |
26 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs755509173 CA3681739 |
26 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201866786 CA3681740 |
27 | V>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3681741 rs749183992 |
31 | H>R | No |
ClinGen ExAC TOPMed |
|
|
rs967848988 CA135805518 |
31 | H>Y | No |
ClinGen Ensembl |
|
|
rs147066723 CA135805520 |
32 | G>A | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3681743 rs147066723 |
32 | G>D | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3681742 rs369163704 |
32 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs373356722 CA135805527 |
33 | W>* | No |
ClinGen ESP gnomAD |
|
|
CA3681744 rs748429265 |
34 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs80184076 CA135805552 |
37 | S>F | No |
ClinGen 1000Genomes |
|
|
rs773230422 CA3681746 |
40 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA3681747 rs138137752 |
42 | S>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs766323123 CA3681748 |
44 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA3681751 rs562088137 COSM303618 |
51 | R>C | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
rs765643034 CA3681752 |
51 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767207132 CA3681755 |
53 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767207132 CA362905559 |
53 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs144390792 CA3681754 |
53 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1456449520 CA362905621 |
56 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
rs755669536 CA3681758 |
58 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA3681759 rs376379490 |
58 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs755669536 CA3681757 |
58 | R>S | No |
ClinGen ExAC gnomAD |
|
|
rs1457718668 CA362905855 |
61 | E>K | No |
ClinGen gnomAD |
|
| TCGA novel | 62 | T>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1325065114 CA362905937 |
63 | L>P | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs754942871 CA3681760 |
64 | G>* | No |
ClinGen ExAC gnomAD |
|
|
CA362905974 rs1438790720 |
64 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1368535863 CA362906011 |
66 | R>* | No |
ClinGen gnomAD |
|
|
COSM3829893 rs202039260 CA3681762 COSM3829894 |
66 | R>Q | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA362906079 rs1404269778 |
69 | L>V | No |
ClinGen TOPMed |
|
|
rs1446254700 CA362906231 |
72 | L>P | No |
ClinGen gnomAD |
|
|
rs1305340418 CA362906225 |
72 | L>V | No |
ClinGen gnomAD |
|
|
CA135805644 rs756145802 |
73 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs771696693 CA3681763 |
74 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA135805649 rs1003540435 |
75 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1380332919 CA362906411 |
77 | H>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1466786086 CA362906659 |
82 | P>R | No |
ClinGen gnomAD |
|
|
rs778079466 CA3681764 |
83 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362906672 rs1160125522 |
83 | D>N | No |
ClinGen TOPMed |
|
| TCGA novel | 84 | L>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1246739563 CA362906753 |
84 | L>S | No |
ClinGen gnomAD |
|
|
rs747161257 CA3681765 |
85 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs201156339 CA3681766 |
89 | Q>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3681767 rs777870600 |
92 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1188675570 CA362907136 |
94 | L>P | No |
ClinGen TOPMed |
|
|
rs1048913319 CA135805667 |
95 | V>E | No |
ClinGen Ensembl |
|
|
rs1048913319 CA362907156 |
95 | V>G | No |
ClinGen Ensembl |
|
|
rs1164202305 CA362907146 |
95 | V>M | No |
ClinGen gnomAD |
|
|
rs1415553856 CA362907228 |
99 | F>V | No |
ClinGen gnomAD |
|
|
CA362907284 rs1354546737 |
100 | L>F | No |
ClinGen TOPMed |
|
|
CA362907323 rs1288217509 |
102 | I>M | No |
ClinGen TOPMed |
|
|
CA135805673 rs956929559 |
102 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA362907409 rs1350494071 |
106 | E>K | No |
ClinGen gnomAD |
|
|
CA3681769 rs770283995 |
107 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA362907627 CA135805685 rs1048319 |
113 | E>D | No |
ClinGen TOPMed |
|
|
rs1229371211 CA362907708 |
115 | Q>E | No |
ClinGen gnomAD |
|
|
CA135805718 rs111518336 |
117 | E>G | No |
ClinGen Ensembl |
|
|
CA362907841 rs1332150130 |
119 | G>V | No |
ClinGen TOPMed |
|
|
rs764314524 CA3681772 |
120 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1581522717 CA362907962 |
122 | V>G | No |
ClinGen Ensembl |
|
|
rs1417553145 CA362907930 |
122 | V>M | No |
ClinGen TOPMed |
|
|
CA3681774 rs760209851 |
125 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681775 rs766034667 |
126 | L>* | No |
ClinGen ExAC gnomAD |
|
|
rs1284851720 CA362908075 |
128 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1483290849 CA362908180 |
131 | R>G | No |
ClinGen gnomAD |
|
|
CA3681778 rs369226061 |
138 | R>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA362908381 rs897169520 |
138 | R>P | No |
ClinGen TOPMed gnomAD |
|
|
CA135805751 rs897169520 |
138 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1478534895 CA362909304 |
143 | R>C | No |
ClinGen TOPMed |
|
|
CA362909314 rs1259018602 |
143 | R>H | No |
ClinGen TOPMed |
|
|
rs199685233 CA3681799 |
144 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs199685233 COSM1194218 CA3681800 |
144 | V>L | lung [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA362909372 rs1581523691 |
145 | H>R | No |
ClinGen Ensembl |
|
|
CA3681801 rs528400956 |
146 | G>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1429190345 CA362909404 |
147 | H>R | No |
ClinGen gnomAD |
|
|
rs781408693 CA3681802 |
148 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA3681803 rs781408693 |
148 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA362909479 rs1233117356 |
150 | L>P | No |
ClinGen gnomAD |
|
|
CA362909482 rs1233117356 |
150 | L>R | No |
ClinGen gnomAD |
|
|
CA362909527 rs1329535445 |
151 | W>* | No |
ClinGen TOPMed gnomAD |
|
|
CA362909571 rs1346919459 |
154 | V>E | No |
ClinGen TOPMed gnomAD |
|
|
CA362909634 rs1445230020 |
156 | H>R | No |
ClinGen gnomAD |
|
|
CA3681806 rs749846565 |
156 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681807 rs769029498 |
158 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA362909716 rs1193305807 |
160 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs772505809 CA3681810 |
161 | P>S | No |
ClinGen ExAC |
|
| TCGA novel | 162 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs62620225 CA3681811 VAR_009877 |
163 | P>L | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA362909882 rs1173561510 |
164 | P>S | No |
ClinGen gnomAD |
|
|
CA362909942 rs1581523827 |
165 | N>S | No |
ClinGen Ensembl |
|
|
CA362909965 rs1384639938 |
166 | T>A | No |
ClinGen gnomAD |
|
|
rs200973986 CA135806317 |
166 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs759235498 CA3681812 |
167 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA362910110 rs1171347623 |
170 | S>F | No |
ClinGen TOPMed |
|
|
CA3681813 rs764889780 |
173 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs1323062905 CA362910175 |
173 | T>S | No |
ClinGen gnomAD |
|
|
CA3681815 rs763017257 |
175 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1300855759 CA362910259 |
175 | H>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 177 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 178 | P>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3681816 rs372113868 |
178 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs376655976 CA3681818 |
180 | P>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs878925275 CA135806394 |
181 | Q>* | No |
ClinGen Ensembl |
|
| TCGA novel | 181 | Q>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs549740955 CA3681819 |
183 | S>* | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs549740955 CA3681820 |
183 | S>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1317098114 CA362910577 |
184 | Q>* | No |
ClinGen Ensembl |
|
|
CA362912484 CA3681845 rs758962715 |
188 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA3681846 rs778349867 |
189 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs747386372 CA3681847 |
190 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771272204 CA3681848 |
191 | S>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1561821338 CA362912608 |
192 | Q>R | No |
ClinGen Ensembl |
|
|
rs375440181 CA3681849 |
194 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs993012276 CA135807687 |
195 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA135807692 rs913186804 |
196 | R>C | No |
ClinGen gnomAD |
|
|
rs768465659 CA3681850 |
196 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA135807698 rs776795883 |
197 | S>C | No |
ClinGen TOPMed |
|
|
CA3681851 rs768087371 |
198 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs773824734 CA3681852 |
204 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA3681853 CA362913211 rs761794277 |
207 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681854 rs199801052 |
208 | T>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs760397894 CA3681856 |
210 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1318458439 CA362913376 |
210 | T>I | No |
ClinGen TOPMed |
|
|
CA362913425 rs1561821423 |
211 | L>R | No |
ClinGen Ensembl |
|
|
CA362913439 rs1258847752 |
212 | L>F | No |
ClinGen gnomAD |
|
|
CA3681858 rs754037685 |
214 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754037685 CA362913554 |
214 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 218 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs763365880 CA3681879 |
219 | L>S | No |
ClinGen ExAC gnomAD |
|
|
rs538735102 CA3681881 |
222 | I>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs201810713 CA3681880 |
222 | I>N | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1414878208 CA362914201 |
223 | E>K | No |
ClinGen TOPMed |
|
| TCGA novel | 224 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs757757157 CA3681882 |
225 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA362914528 rs1561821636 |
230 | I>T | No |
ClinGen Ensembl |
|
|
COSM1271068 CA3681884 rs750793074 |
231 | R>* | oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1303880529 CA362914538 |
231 | R>Q | No |
ClinGen gnomAD |
|
|
CA362914568 rs1313084097 |
232 | E>A | No |
ClinGen TOPMed gnomAD |
|
|
COSM1545688 CA3681885 rs756363905 |
234 | W>C | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 235 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1319578085 CA362914719 |
235 | L>H | No |
ClinGen gnomAD |
|
|
rs373001897 CA3681886 |
235 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs747748752 CA3681887 |
236 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1214751971 CA362914843 |
237 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA3681890 rs777233536 |
237 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681889 rs777233536 |
237 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681888 rs757935459 |
237 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
CA362914881 rs1188666880 |
238 | P>L | No |
ClinGen TOPMed |
|
|
rs1192497923 CA362914854 |
238 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA3681891 rs770898037 |
239 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA135807963 rs957792349 |
240 | Q>R | No |
ClinGen TOPMed |
|
|
CA362915065 rs1457668592 |
244 | C>Y | No |
ClinGen gnomAD |
|
|
rs921567159 CA135807972 |
245 | R>G | No |
ClinGen TOPMed |
|
|
CA135807979 rs912885577 |
245 | R>S | No |
ClinGen TOPMed |
|
|
CA3681895 rs775888299 |
246 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681897 rs763241262 |
251 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681896 rs763241262 |
251 | N>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1295506026 CA362915240 |
251 | N>S | No |
ClinGen gnomAD |
|
|
rs555204173 CA135807998 |
253 | R>G | No |
ClinGen Ensembl |
|
|
rs1581526999 CA362915318 |
255 | M>V | No |
ClinGen Ensembl |
|
|
rs1581527015 CA362915354 |
256 | F>L | No |
ClinGen Ensembl |
|
|
CA3681899 rs762291804 |
257 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA135808011 rs762291804 |
257 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs182859095 CA3681908 |
259 | G>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA362915532 rs182859095 |
259 | G>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs955337682 CA135808020 |
259 | G>S | No |
ClinGen Ensembl |
|
| TCGA novel | 260 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs781214853 CA3681909 |
260 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA362915557 rs1293198205 |
261 | E>K | No |
ClinGen gnomAD |
|
|
CA3681910 rs745755465 |
262 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA362915670 rs1581527883 |
264 | S>R | No |
ClinGen Ensembl |
|
|
rs953115418 CA135808480 |
269 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA3681912 rs779976276 |
270 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs1435796655 CA362915849 |
270 | A>V | No |
ClinGen TOPMed |
|
|
CA362915854 rs1390536311 |
271 | S>T | No |
ClinGen TOPMed |
|
|
rs1187210482 CA362915900 |
272 | K>R | No |
ClinGen gnomAD |
|
|
rs1235647434 CA362915940 |
274 | V>L | No |
ClinGen gnomAD |
|
|
CA3681913 rs577067470 |
275 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3681914 rs768991197 |
276 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA362916004 rs1456336597 |
276 | S>F | No |
ClinGen TOPMed |
|
|
CA135808487 rs768991197 |
276 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs1414550800 CA362916022 |
277 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA3681915 rs774367513 |
278 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA135808490 rs146221234 |
279 | I>M | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA362916106 rs1166937987 |
279 | I>T | No |
ClinGen gnomAD |
|
|
CA3681917 rs771995321 |
281 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1334129646 CA362916155 |
282 | H>D | No |
ClinGen gnomAD |
|
|
CA362916201 rs1357958237 |
282 | H>R | No |
ClinGen gnomAD |
|
|
rs773797804 CA3681918 |
283 | G>E | No |
ClinGen ExAC gnomAD |
|
|
rs1450750511 CA362916245 |
283 | G>R | No |
ClinGen gnomAD |
|
|
CA3681919 rs565242305 |
285 | T>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs754198301 CA362916395 CA3681921 |
288 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1342675295 CA362916382 |
288 | K>R | No |
ClinGen gnomAD |
|
|
rs555727854 CA135808561 |
290 | N>S | No |
ClinGen gnomAD |
|
|
rs763822634 CA3681923 |
291 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 293 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1238186914 CA362916576 |
295 | R>G | No |
ClinGen gnomAD |
|
|
CA362916584 rs1448923230 |
295 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA362916614 rs62401435 |
296 | G>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3681926 rs62401435 |
296 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA362916653 COSM1311916 rs1450279216 |
298 | E>Q | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs750438291 CA3681927 |
299 | H>R | No |
ClinGen ExAC TOPMed |
|
|
CA3681929 rs748309826 |
303 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681930 rs144897733 |
303 | R>Q | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1561822513 CA362916851 |
304 | D>E | No |
ClinGen Ensembl |
|
|
CA362916865 rs1335446269 |
305 | L>F | No |
ClinGen gnomAD |
|
|
CA362916910 rs749096234 |
306 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362916993 rs1322188004 |
309 | L>F | No |
ClinGen gnomAD |
|
|
rs1432240996 CA362916985 |
309 | L>S | No |
ClinGen gnomAD |
|
|
CA362917066 rs951893023 |
312 | Q>H | No |
ClinGen TOPMed |
|
|
rs149099230 COSM451100 CA3681933 |
313 | R>Q | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs147775187 CA3681932 |
313 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3681934 rs748277275 |
314 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA3681935 rs772233034 |
314 | G>V | No |
ClinGen ExAC |
|
|
CA3681936 rs773142736 |
315 | N>H | No |
ClinGen ExAC gnomAD |
|
|
rs1267398438 CA362917262 |
319 | E>K | No |
ClinGen gnomAD |
|
|
CA362917323 rs1348765007 |
320 | R>T | No |
ClinGen TOPMed |
|
|
CA3681938 rs373665045 |
321 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs777066140 CA3681939 |
321 | R>Q | Variant assessed as Somatic; 4.619e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA362917401 rs1388870630 |
322 | H>R | No |
ClinGen TOPMed |
|
|
CA3681940 rs141092348 |
325 | D>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3681941 rs765480776 |
327 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs751267874 CA3681942 |
327 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1376354797 CA362917716 |
328 | G>A | No |
ClinGen gnomAD |
|
|
rs377511142 CA135808662 |
332 | A>V | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA362918005 rs1581528389 |
334 | S>N | No |
ClinGen Ensembl |
|
|
TCGA novel CA3681944 rs200386851 |
334 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
rs749943899 CA135808670 |
337 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749943899 CA3681945 |
337 | L>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362919916 rs1456076989 |
338 | V>I | No |
ClinGen gnomAD |
|
|
rs766590475 CA3681946 |
339 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs766430041 CA3681947 |
339 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362919996 rs1385934589 |
341 | W>* | No |
ClinGen gnomAD |
|
|
CA362920104 rs147815432 |
345 | T>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs147815432 CA3681948 |
345 | T>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1436893173 CA362920135 |
347 | E>K | No |
ClinGen gnomAD |
|
|
rs1287442952 CA362920186 |
349 | P>L | No |
ClinGen gnomAD |
|
| TCGA novel | 349 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA362920223 rs1281422399 |
351 | Q>E | No |
ClinGen gnomAD |
|
|
rs748450133 CA3681951 |
352 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1270098157 CA362920248 |
352 | C>S | No |
ClinGen gnomAD |
|
|
CA362920276 rs1353650168 |
353 | N>D | No |
ClinGen gnomAD |
|
|
CA362920289 rs1209530271 |
353 | N>S | No |
ClinGen gnomAD |
|
|
CA362920305 rs1215038475 |
354 | V>E | No |
ClinGen gnomAD |
|
|
CA3681952 rs758535949 |
354 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA362920336 rs1453731905 |
356 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
CA135808706 rs774965785 |
356 | G>D | No |
ClinGen Ensembl |
|
|
CA3681953 rs777904283 |
358 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1384678541 CA362920384 |
358 | A>T | No |
ClinGen TOPMed |
|
|
CA3681954 rs747105228 |
359 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA3681955 rs770950378 |
361 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1411127790 CA362920465 |
362 | R>S | No |
ClinGen TOPMed |
|
|
CA3681956 rs777155921 |
362 | R>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362920481 rs1412138471 |
364 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA3681957 rs746345307 |
367 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362920543 rs1161133760 |
369 | Q>* | No |
ClinGen gnomAD |
|
|
CA3681959 rs775707878 |
370 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770246159 CA3681958 |
370 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1348321636 CA362920606 |
373 | N>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA135808739 rs528247438 |
374 | K>Q | No |
ClinGen Ensembl |
|
|
rs767076953 CA3681961 |
376 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA3681962 rs772937846 |
377 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760280814 CA3681963 |
377 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA3681964 rs765945582 |
378 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765945582 CA362920673 |
378 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1244118632 CA362920666 |
378 | Y>H | No |
ClinGen gnomAD |
|
|
rs1244118632 CA362920668 |
378 | Y>N | No |
ClinGen gnomAD |
|
|
rs754820951 CA135808758 |
379 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
rs753865572 CA3681965 |
382 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs753865572 CA3681966 |
382 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs1345569064 CA362920717 |
382 | E>K | No |
ClinGen gnomAD |
|
| TCGA novel | 383 | C>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3681967 rs200171310 |
384 | G>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA362920755 rs1412981892 |
384 | G>S | No |
ClinGen TOPMed |
|
| TCGA novel | 385 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3681968 rs752440213 |
386 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1423701129 CA362920854 |
388 | S>R | No |
ClinGen gnomAD |
|
|
CA362920981 rs1472923759 |
393 | L>P | No |
ClinGen gnomAD |
|
|
rs757370899 CA3681972 |
397 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681973 rs781229764 |
398 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA362921073 rs1483556621 |
398 | R>K | No |
ClinGen TOPMed |
|
|
CA3681974 rs746448853 |
401 | T>S | No |
ClinGen ExAC |
|
|
rs775993647 CA3681976 |
402 | G>W | No |
ClinGen ExAC |
|
|
rs769012626 CA3681978 |
403 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769012626 CA135808799 |
403 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3681980 rs760370717 |
404 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA3681981 rs760370717 |
404 | K>T | No |
ClinGen ExAC gnomAD |
|
|
rs927293326 CA135808820 |
405 | P>Q | No |
ClinGen TOPMed |
|
|
CA362921283 rs927293326 |
405 | P>R | No |
ClinGen TOPMed |
|
|
rs776266936 CA3681982 |
405 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1297107706 CA362921297 |
406 | Y>H | No |
ClinGen gnomAD |
|
|
rs1195286725 CA362921330 |
407 | Q>* | No |
ClinGen gnomAD |
|
|
CA3681984 rs62620226 |
407 | Q>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs752632960 CA3681985 |
408 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA362921365 rs1229907648 |
408 | C>R | No |
ClinGen TOPMed |
|
|
rs200170770 CA3681986 |
409 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs763848309 CA3681987 |
411 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs1327649491 CA362921552 |
414 | A>D | No |
ClinGen TOPMed |
|
|
rs1257738807 CA362921625 |
417 | Q>P | No |
ClinGen gnomAD |
|
|
rs201882419 CA135808846 |
418 | S>N | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs201882419 CA362921653 |
418 | S>T | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs990145539 CA135808848 |
419 | A>V | No |
ClinGen gnomAD |
|
|
rs781320407 CA3681990 COSM595440 |
420 | G>S | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA135808885 rs1008564773 |
422 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA3681991 rs750477732 |
426 | R>S | No |
ClinGen ExAC gnomAD |
|
|
rs867546676 CA135808933 |
432 | R>K | No |
ClinGen Ensembl |
|
|
rs1404497434 CA362922183 |
436 | C>S | No |
ClinGen gnomAD |
|
|
CA362922287 rs1465853192 |
439 | C>R | No |
ClinGen TOPMed |
|
|
CA3681996 rs779396389 |
445 | H>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA135808970 rs1042304863 |
447 | S>P | No |
ClinGen Ensembl |
|
|
rs878870374 CA135808973 |
448 | H>L | No |
ClinGen Ensembl |
|
|
CA3681999 rs776289727 |
450 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs961774941 CA135808983 |
454 | R>G | No |
ClinGen TOPMed |
|
|
rs1581529202 CA362922679 |
456 | H>R | No |
ClinGen Ensembl |
|
|
CA362922695 rs1400778611 |
457 | T>A | No |
ClinGen gnomAD |
|
|
CA3682002 rs200133233 |
457 | T>N | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs200133233 CA3682001 |
457 | T>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3682003 rs762927371 |
458 | G>E | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 459 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3682005 rs751355006 |
461 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA3682008 rs750605583 |
462 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs879120592 CA135809036 |
463 | E>Q | No |
ClinGen Ensembl |
|
|
CA362922836 rs1431205610 |
464 | C>G | No |
ClinGen gnomAD |
|
|
CA135809040 rs879034955 |
465 | D>N | No |
ClinGen Ensembl |
|
|
rs1429941994 CA362922876 |
466 | E>K | No |
ClinGen gnomAD |
|
|
rs377494049 CA135809043 |
469 | K>* | No |
ClinGen Ensembl |
|
|
rs756435534 CA362922951 |
469 | K>N | No |
ClinGen TOPMed |
|
|
rs1456591764 CA362922958 |
470 | T>A | No |
ClinGen gnomAD |
|
|
CA362922956 rs1456591764 |
470 | T>S | No |
ClinGen gnomAD |
|
|
rs1027600020 CA135809045 |
472 | R>G | No |
ClinGen TOPMed |
|
|
rs1322232151 CA362923025 |
474 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
CA3682011 rs754350277 |
475 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA362923048 rs1289652112 |
475 | S>L | No |
ClinGen gnomAD |
|
|
CA362923056 rs1581529391 |
476 | H>Y | No |
ClinGen Ensembl |
|
| TCGA novel | 477 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA135809057 rs1039422870 |
478 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA3682012 rs755526546 |
479 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs779486902 CA3682013 |
480 | H>D | No |
ClinGen ExAC gnomAD |
|
|
rs1311192112 CA362923150 |
481 | Q>E | No |
ClinGen TOPMed |
|
|
rs1438108322 CA362923231 |
485 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1324911455 CA362923244 |
486 | G>E | No |
ClinGen gnomAD |
|
|
CA362923253 rs1366345344 |
487 | E>K | No |
ClinGen TOPMed |
|
|
CA362923320 rs1265704825 |
490 | Y>* | No |
ClinGen gnomAD |
|
|
CA362923363 rs1323008385 |
492 | C>W | No |
ClinGen TOPMed |
|
|
rs764882897 CA3682015 |
493 | N>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764882897 CA135809065 |
493 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1264457042 CA362923389 |
494 | E>A | No |
ClinGen gnomAD |
|
|
rs866337221 CA135809084 |
497 | R>K | No |
ClinGen TOPMed |
|
|
CA362923467 rs1192725294 |
498 | A>V | No |
ClinGen gnomAD |
|
|
rs745504497 CA3682017 |
499 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs769238231 CA362923512 |
501 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3682018 rs769238231 |
501 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 501 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1366849598 CA362923590 |
505 | L>P | No |
ClinGen TOPMed |
|
|
rs775054732 CA3682019 |
506 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs768581035 CA3682021 |
509 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA135809106 rs899512356 |
510 | R>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs761622582 CA3682023 |
521 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1581529597 CA362923947 |
522 | E>Q | No |
ClinGen Ensembl |
|
|
CA135809117 rs374171305 |
522 | E>V | No |
ClinGen ESP |
|
|
CA362923995 rs1409826273 |
524 | G>R | No |
ClinGen gnomAD |
|
|
rs1286992701 CA362924047 |
526 | A>V | No |
ClinGen gnomAD |
|
|
rs767307348 CA3682024 |
528 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1190297240 CA362924223 |
535 | Q>* | No |
ClinGen TOPMed |
|
|
CA3682027 rs766429406 |
539 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362924339 rs1223225660 |
541 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1561823869 CA362924358 |
542 | G>E | No |
ClinGen Ensembl |
|
|
CA362924354 rs1482598183 |
542 | G>R | No |
ClinGen gnomAD |
|
|
rs755042766 CA3682030 |
548 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA3682031 rs765867822 |
549 | N>I | No |
ClinGen ExAC gnomAD |
|
|
CA3682032 rs765867822 |
549 | N>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 549 | N>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1413092878 CA362924598 |
550 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs758873700 CA3682033 |
553 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA362924796 rs1429473972 |
558 | R>K | No |
ClinGen gnomAD |
|
|
CA362924838 rs1209328063 |
560 | S>G | No |
ClinGen gnomAD |
|
|
rs1443484931 CA362924849 |
560 | S>N | No |
ClinGen gnomAD |
|
|
COSM1233664 CA362924889 rs1300204615 |
563 | R>* | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA3682036 rs757866322 |
564 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs1433360083 CA362924929 |
565 | Q>* | No |
ClinGen TOPMed |
|
|
rs1315282160 CA362925049 |
569 | S>G | No |
ClinGen gnomAD |
|
| TCGA novel | 571 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs374105856 CA3682038 |
573 | S>C | No |
ClinGen ESP ExAC TOPMed |
|
| TCGA novel | 573 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1388790025 CA362925299 |
575 | S>Y | No |
ClinGen TOPMed |
|
|
rs1561824061 CA362925315 |
576 | I>V | No |
ClinGen Ensembl |
|
|
CA3682041 rs142219933 |
578 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA362925400 rs142219933 |
578 | V>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3682042 rs748049885 |
579 | V>Q | No |
ClinGen ExAC |
No associated diseases with Q15776
11 regional properties for Q15776
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Krueppel-associated box | 220 - 316 | IPR001909 |
| domain | SCAN domain | 47 - 159 | IPR003309 |
| domain | Zinc finger C2H2-type | 322 - 349 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 350 - 377 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 378 - 405 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 406 - 433 | IPR013087-4 |
| domain | Zinc finger C2H2-type | 434 - 461 | IPR013087-5 |
| domain | Zinc finger C2H2-type | 462 - 489 | IPR013087-6 |
| domain | Zinc finger C2H2-type | 490 - 517 | IPR013087-7 |
| domain | Zinc finger C2H2-type | 518 - 545 | IPR013087-8 |
| domain | Zinc finger C2H2-type | 546 - 573 | IPR013087-9 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| metal ion binding | Binding to a metal ion. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
177 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08DS3 | OSR1 | Protein odd-skipped-related 1 | Bos taurus (Bovine) | PR |
| Q2VWH6 | FEZF2 | Fez family zinc finger protein 2 | Bos taurus (Bovine) | PR |
| A6QNZ0 | ZSCAN26 | Zinc finger and SCAN domain-containing protein 26 | Bos taurus (Bovine) | PR |
| A7MBI1 | ZFP69 | Zinc finger protein 69 homolog | Bos taurus (Bovine) | PR |
| Q08705 | CTCF | Transcriptional repressor CTCF | Gallus gallus (Chicken) | PR |
| O42409 | GFI1B | Zinc finger protein Gfi-1b | Gallus gallus (Chicken) | PR |
| A2T6W2 | ZNF449 | Zinc finger protein 449 | Pan troglodytes (Chimpanzee) | PR |
| Q9U405 | grau | Transcription factor grauzone | Drosophila melanogaster (Fruit fly) | PR |
| Q7K0S9 | sug | Zinc finger protein GLIS2 homolog | Drosophila melanogaster (Fruit fly) | PR |
| P20385 | Cf2 | Chorion transcription factor Cf2 | Drosophila melanogaster (Fruit fly) | PR |
| Q86P48 | ATbp | AT-rich binding protein | Drosophila melanogaster (Fruit fly) | PR |
| P28698 | MZF1 | Myeloid zinc finger 1 | Homo sapiens (Human) | PR |
| Q9NTW7 | ZFP64 | Zinc finger protein 64 | Homo sapiens (Human) | PR |
| P08151 | GLI1 | Zinc finger protein GLI1 | Homo sapiens (Human) | PR |
| Q9UFB7 | ZBTB47 | Zinc finger and BTB domain-containing protein 47 | Homo sapiens (Human) | PR |
| P18146 | EGR1 | Early growth response protein 1 | Homo sapiens (Human) | PR |
| Q9Y5W3 | KLF2 | Krueppel-like factor 2 | Homo sapiens (Human) | PR |
| Q96SZ4 | ZSCAN10 | Zinc finger and SCAN domain-containing protein 10 | Homo sapiens (Human) | PR |
| P57682 | KLF3 | Krueppel-like factor 3 | Homo sapiens (Human) | PR |
| P25490 | YY1 | Transcriptional repressor protein YY1 | Homo sapiens (Human) | SS |
| O43296 | ZNF264 | Zinc finger protein 264 | Homo sapiens (Human) | PR |
| P49711 | CTCF | Transcriptional repressor CTCF | Homo sapiens (Human) | PR |
| Q9NQX1 | PRDM5 | PR domain zinc finger protein 5 | Homo sapiens (Human) | PR |
| Q9HBE1 | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 | Homo sapiens (Human) | PR |
| Q8TAX0 | OSR1 | Protein odd-skipped-related 1 | Homo sapiens (Human) | PR |
| Q8TBJ5 | FEZF2 | Fez family zinc finger protein 2 | Homo sapiens (Human) | PR |
| Q96SR6 | ZNF382 | Zinc finger protein 382 | Homo sapiens (Human) | PR |
| Q9ULJ3 | ZBTB21 | Zinc finger and BTB domain-containing protein 21 | Homo sapiens (Human) | PR |
| O75840 | KLF7 | Krueppel-like factor 7 | Homo sapiens (Human) | PR |
| Q13127 | REST | RE1-silencing transcription factor | Homo sapiens (Human) | PR |
| Q8IZM8 | ZNF654 | Zinc finger protein 654 | Homo sapiens (Human) | PR |
| Q14526 | HIC1 | Hypermethylated in cancer 1 protein | Homo sapiens (Human) | PR |
| Q06889 | EGR3 | Early growth response protein 3 | Homo sapiens (Human) | PR |
| Q08ER8 | ZNF543 | Zinc finger protein 543 | Homo sapiens (Human) | PR |
| Q8N680 | ZBTB2 | Zinc finger and BTB domain-containing protein 2 | Homo sapiens (Human) | PR |
| O95625 | ZBTB11 | Zinc finger and BTB domain-containing protein 11 | Homo sapiens (Human) | PR |
| Q96BV0 | ZNF775 | Zinc finger protein 775 | Homo sapiens (Human) | PR |
| Q5FWF6 | ZNF789 | Zinc finger protein 789 | Homo sapiens (Human) | PR |
| Q05516 | ZBTB16 | Zinc finger and BTB domain-containing protein 16 | Homo sapiens (Human) | PR |
| Q9H116 | GZF1 | GDNF-inducible zinc finger protein 1 | Homo sapiens (Human) | PR |
| Q8IW36 | ZNF695 | Zinc finger protein 695 | Homo sapiens (Human) | PR |
| Q5VTD9 | GFI1B | Zinc finger protein Gfi-1b | Homo sapiens (Human) | PR |
| Q6PG37 | ZNF790 | Zinc finger protein 790 | Homo sapiens (Human) | PR |
| Q9NQV6 | PRDM10 | PR domain zinc finger protein 10 | Homo sapiens (Human) | PR |
| Q9Y2D9 | ZNF652 | Zinc finger protein 652 | Homo sapiens (Human) | PR |
| Q5TC79 | ZBTB37 | Zinc finger and BTB domain-containing protein 37 | Homo sapiens (Human) | PR |
| Q9Y4E5 | ZNF451 | E3 SUMO-protein ligase ZNF451 | Homo sapiens (Human) | PR |
| Q8ND82 | ZNF280C | Zinc finger protein 280C | Homo sapiens (Human) | PR |
| Q49AA0 | ZFP69 | Zinc finger protein 69 homolog | Homo sapiens (Human) | PR |
| O43298 | ZBTB43 | Zinc finger and BTB domain-containing protein 43 | Homo sapiens (Human) | PR |
| Q9Y330 | ZBTB12 | Zinc finger and BTB domain-containing protein 12 | Homo sapiens (Human) | PR |
| Q13105 | ZBTB17 | Zinc finger and BTB domain-containing protein 17 | Homo sapiens (Human) | PR |
| P51508 | ZNF81 | Zinc finger protein 81 | Homo sapiens (Human) | PR |
| Q5JNZ3 | ZNF311 | Zinc finger protein 311 | Homo sapiens (Human) | PR |
| Q9Y4X4 | KLF12 | Krueppel-like factor 12 | Homo sapiens (Human) | PR |
| P10074 | ZBTB48 | Telomere zinc finger-associated protein | Homo sapiens (Human) | PR |
| P17010 | ZFX | Zinc finger X-chromosomal protein | Homo sapiens (Human) | PR |
| Q9H5H4 | ZNF768 | Zinc finger protein 768 | Homo sapiens (Human) | PR |
| Q86UZ6 | ZBTB46 | Zinc finger and BTB domain-containing protein 46 | Homo sapiens (Human) | PR |
| Q8NCP5 | ZBTB44 | Zinc finger and BTB domain-containing protein 44 | Homo sapiens (Human) | PR |
| P41182 | BCL6 | B-cell lymphoma 6 protein | Homo sapiens (Human) | PR |
| Q9NQX0 | PRDM6 | Putative histone-lysine N-methyltransferase PRDM6 | Homo sapiens (Human) | PR |
| Q9BU19 | ZNF692 | Zinc finger protein 692 | Homo sapiens (Human) | PR |
| Q08AG5 | ZNF844 | Zinc finger protein 844 | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| P98182 | ZNF200 | Zinc finger protein 200 | Homo sapiens (Human) | PR |
| Q9UK11 | ZNF223 | Zinc finger protein 223 | Homo sapiens (Human) | PR |
| O15156 | ZBTB7B | Zinc finger and BTB domain-containing protein 7B | Homo sapiens (Human) | PR |
| Q6ZMS7 | ZNF783 | Zinc finger protein 783 | Homo sapiens (Human) | PR |
| P59923 | ZNF445 | Zinc finger protein 445 | Homo sapiens (Human) | PR |
| Q8N859 | ZNF713 | Zinc finger protein 713 | Homo sapiens (Human) | PR |
| Q99612 | KLF6 | Krueppel-like factor 6 | Homo sapiens (Human) | PR |
| Q8TD17 | ZNF398 | Zinc finger protein 398 | Homo sapiens (Human) | PR |
| P52739 | ZNF131 | Zinc finger protein 131 | Homo sapiens (Human) | PR |
| Q05215 | EGR4 | Early growth response protein 4 | Homo sapiens (Human) | PR |
| Q7Z398 | ZNF550 | Zinc finger protein 550 | Homo sapiens (Human) | PR |
| Q9Y2K1 | ZBTB1 | Zinc finger and BTB domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q96N20 | ZNF75A | Zinc finger protein 75A | Homo sapiens (Human) | PR |
| A1YPR0 | ZBTB7C | Zinc finger and BTB domain-containing protein 7C | Homo sapiens (Human) | PR |
| P24278 | ZBTB25 | Zinc finger and BTB domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q96N38 | ZNF714 | Zinc finger protein 714 | Homo sapiens (Human) | PR |
| Q86YH2 | ZNF280B | Zinc finger protein 280B | Homo sapiens (Human) | PR |
| Q9Y2L8 | ZKSCAN5 | Zinc finger protein with KRAB and SCAN domains 5 | Homo sapiens (Human) | PR |
| Q8NAM6 | ZSCAN4 | Zinc finger and SCAN domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q9NPC7 | MYNN | Myoneurin | Homo sapiens (Human) | PR |
| O14978 | ZNF263 | Zinc finger protein 263 | Homo sapiens (Human) | PR |
| P17022 | ZNF18 | Zinc finger protein 18 | Homo sapiens (Human) | PR |
| Q6P9G9 | ZNF449 | Zinc finger protein 449 | Homo sapiens (Human) | PR |
| O60304 | ZNF500 | Zinc finger protein 500 | Homo sapiens (Human) | PR |
| Q9NX65 | ZSCAN32 | Zinc finger and SCAN domain-containing protein 32 | Homo sapiens (Human) | PR |
| Q96IT1 | ZNF496 | Zinc finger protein 496 | Homo sapiens (Human) | PR |
| O14771 | ZNF213 | Zinc finger protein 213 | Homo sapiens (Human) | PR |
| O95125 | ZNF202 | Zinc finger protein 202 | Homo sapiens (Human) | PR |
| Q8IWY8 | ZSCAN29 | Zinc finger and SCAN domain-containing protein 29 | Homo sapiens (Human) | PR |
| Q8N0Y2 | ZNF444 | Zinc finger protein 444 | Homo sapiens (Human) | PR |
| A6NGD5 | ZSCAN5C | Zinc finger and SCAN domain-containing protein 5C | Homo sapiens (Human) | PR |
| A6NJL1 | ZSCAN5B | Zinc finger and SCAN domain-containing protein 5B | Homo sapiens (Human) | PR |
| Q8NF99 | ZNF397 | Zinc finger protein 397 | Homo sapiens (Human) | PR |
| Q86XF7 | ZNF575 | Zinc finger protein 575 | Homo sapiens (Human) | PR |
| Q9NWS9 | ZNF446 | Zinc finger protein 446 | Homo sapiens (Human) | PR |
| Q96N95 | ZNF396 | Zinc finger protein 396 | Homo sapiens (Human) | PR |
| Q9UL58 | ZNF215 | Zinc finger protein 215 | Homo sapiens (Human) | PR |
| P17029 | ZKSCAN1 | Zinc finger protein with KRAB and SCAN domains 1 | Homo sapiens (Human) | PR |
| Q53GI3 | ZNF394 | Zinc finger protein 394 | Homo sapiens (Human) | PR |
| Q9BRR0 | ZKSCAN3 | Zinc finger protein with KRAB and SCAN domains 3 | Homo sapiens (Human) | PR |
| Q969J2 | ZKSCAN4 | Zinc finger protein with KRAB and SCAN domains 4 | Homo sapiens (Human) | PR |
| Q6NSZ9 | ZSCAN25 | Zinc finger and SCAN domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q9UNY5 | ZNF232 | Zinc finger protein 232 | Homo sapiens (Human) | PR |
| P17028 | ZNF24 | Zinc finger protein 24 | Homo sapiens (Human) | PR |
| Q63HK3 | ZKSCAN2 | Zinc finger protein with KRAB and SCAN domains 2 | Homo sapiens (Human) | PR |
| P49910 | ZNF165 | Zinc finger protein 165 | Homo sapiens (Human) | PR |
| Q9H9D4 | ZNF408 | Zinc finger protein 408 | Homo sapiens (Human) | PR |
| O08584 | Klf6 | Krueppel-like factor 6 | Mus musculus (Mouse) | PR |
| Q61164 | Ctcf | Transcriptional repressor CTCF | Mus musculus (Mouse) | PR |
| Q810A1 | Znf18 | Zinc finger protein 18 | Mus musculus (Mouse) | PR |
| Q8BGS3 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Mus musculus (Mouse) | PR |
| Q00899 | Yy1 | Transcriptional repressor protein YY1 | Mus musculus (Mouse) | PR |
| P41183 | Bcl6 | B-cell lymphoma 6 protein homolog | Mus musculus (Mouse) | PR |
| Q9DAI4 | Zbtb43 | Zinc finger and BTB domain-containing protein 43 | Mus musculus (Mouse) | PR |
| O70237 | Gfi1b | Zinc finger protein Gfi-1b | Mus musculus (Mouse) | PR |
| Q99KZ6 | Znf639 | Zinc finger protein 639 | Mus musculus (Mouse) | PR |
| Q9Z1D9 | Znf394 | Zinc finger protein 394 | Mus musculus (Mouse) | PR |
| Q9CXE0 | Prdm5 | PR domain zinc finger protein 5 | Mus musculus (Mouse) | PR |
| P43300 | Egr3 | Early growth response protein 3 | Mus musculus (Mouse) | PR |
| Q9DAU9 | Znf654 | Zinc finger protein 654 | Mus musculus (Mouse) | PR |
| Q9R1Y5 | Hic1 | Hypermethylated in cancer 1 protein | Mus musculus (Mouse) | PR |
| Q8R0T2 | Znf768 | Zinc finger protein 768 | Mus musculus (Mouse) | PR |
| Q9WVG7 | Osr1 | Protein odd-skipped-related 1 | Mus musculus (Mouse) | PR |
| Q8BI73 | Znf775 | Zinc finger protein 775 | Mus musculus (Mouse) | PR |
| Q8VCZ7 | Zbtb7c | Zinc finger and BTB domain-containing protein 7C | Mus musculus (Mouse) | PR |
| Q91VN1 | Znf24 | Zinc finger protein 24 | Mus musculus (Mouse) | PR |
| Q9DB38 | Znf580 | Zinc finger protein 580 | Mus musculus (Mouse) | PR |
| A7KBS4 | Zscan4d | Zinc finger and SCAN domain containing protein 4D | Mus musculus (Mouse) | PR |
| Q91VW9 | Zkscan3 | Zinc finger protein with KRAB and SCAN domains 3 | Mus musculus (Mouse) | PR |
| P10925 | Zfy1 | Zinc finger Y-chromosomal protein 1 | Mus musculus (Mouse) | PR |
| P08046 | Egr1 | Early growth response protein 1 | Mus musculus (Mouse) | PR |
| Q3TTC2 | Yy2 | Transcription factor YY2 | Mus musculus (Mouse) | PR |
| Q3UTQ7 | Prdm10 | PR domain zinc finger protein 10 | Mus musculus (Mouse) | PR |
| Q6P3Y5 | Znf280c | Zinc finger protein 280C | Mus musculus (Mouse) | PR |
| Q9ERU3 | Znf22 | Zinc finger protein 22 | Mus musculus (Mouse) | PR |
| Q8VIG1 | Rest | RE1-silencing transcription factor | Mus musculus (Mouse) | PR |
| Q8BID6 | Zbtb46 | Zinc finger and BTB domain-containing protein 46 | Mus musculus (Mouse) | PR |
| P17012 | Zfx | Zinc finger X-chromosomal protein | Mus musculus (Mouse) | PR |
| Q9WUK6 | Zbtb18 | Zinc finger and BTB domain-containing protein 18 | Mus musculus (Mouse) | PR |
| O35738 | Klf12 | Krueppel-like factor 12 | Mus musculus (Mouse) | PR |
| B2RXC5 | Znf382 | Zinc finger protein 382 | Mus musculus (Mouse) | PR |
| O08900 | Ikzf3 | Zinc finger protein Aiolos | Mus musculus (Mouse) | PR |
| Q5DU09 | Znf652 | Zinc finger protein 652 | Mus musculus (Mouse) | PR |
| Q5RJ54 | Zscan26 | Zinc finger and SCAN domain-containing protein 26 | Mus musculus (Mouse) | PR |
| Q8BLM0 | Klf8 | Krueppel-like factor 8 | Mus musculus (Mouse) | PR |
| Q99JB0 | Klf7 | Krueppel-like factor 7 | Mus musculus (Mouse) | PR |
| Q8R0A2 | Zbtb44 | Zinc finger and BTB domain-containing protein 44 | Mus musculus (Mouse) | PR |
| P20662 | Zfy2 | Zinc finger Y-chromosomal protein 2 | Mus musculus (Mouse) | PR |
| Q80VJ6 | Zscan4c | Zinc finger and SCAN domain containing protein 4C | Mus musculus (Mouse) | PR |
| Q3URS2 | Zscan4f | Zinc finger and SCAN domain containing protein 4F | Mus musculus (Mouse) | PR |
| Q60980 | Klf3 | Krueppel-like factor 3 | Mus musculus (Mouse) | PR |
| Q8K3J5 | Znf131 | Zinc finger protein 131 | Mus musculus (Mouse) | PR |
| Q9Z1D8 | Zkscan5 | Zinc finger protein with KRAB and SCAN domains 5 | Mus musculus (Mouse) | PR |
| Q9Z2K3 | Znf394 | Zinc finger protein 394 | Rattus norvegicus (Rat) | PR |
| Q642B9 | Znf18 | Zinc finger protein 18 | Rattus norvegicus (Rat) | PR |
| B0K011 | Osr1 | Protein odd-skipped-related 1 | Rattus norvegicus (Rat) | PR |
| D3ZUU2 | Gzf1 | GDNF-inducible zinc finger protein 1 | Rattus norvegicus (Rat) | PR |
| B1WBU4 | Zbtb8a | Zinc finger and BTB domain-containing protein 8A | Rattus norvegicus (Rat) | PR |
| Q7TNK3 | Znf24 | Zinc finger protein 24 | Rattus norvegicus (Rat) | PR |
| O35819 | Klf6 | Krueppel-like factor 6 | Rattus norvegicus (Rat) | PR |
| Q9R1D1 | Ctcf | Transcriptional repressor CTCF | Rattus norvegicus (Rat) | PR |
| P43301 | Egr3 | Early growth response protein 3 | Rattus norvegicus (Rat) | PR |
| P08154 | Egr1 | Early growth response protein 1 | Rattus norvegicus (Rat) | PR |
| A0JPL0 | Znf382 | Zinc finger protein 382 | Rattus norvegicus (Rat) | PR |
| Q4KLI1 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Rattus norvegicus (Rat) | PR |
| A1L1J6 | Znf652 | Zinc finger protein 652 | Rattus norvegicus (Rat) | PR |
| Q9SHD0 | ZAT4 | Zinc finger protein ZAT4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0P4X6 | zbtb44 | Zinc finger and BTB domain-containing protein 44 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A4II20 | egr1 | Early growth response protein 1 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q6P882 | zbtb8a.2 | Zinc finger and BTB domain-containing protein 8A.2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q567C6 | znf367 | Zinc finger protein 367 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| A7Y7X5 | znf711 | Zinc finger protein 711 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEESRKPSA | PSPPDQTPEE | DLVIVKVEED | HGWDQESSLH | ESNPLGQEVF | RLRFRQLRYQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ETLGPREALI | QLRALCHQWL | RPDLNTKEQI | LELLVLEQFL | TILPEELQTL | VKEHQLENGE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EVVTLLEDLE | RQIDILGRPV | SARVHGHRVL | WEEVVHSASA | PEPPNTQLQS | EATQHKSPVP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QESQERAMST | SQSPTRSQKG | SSGDQEMTAT | LLTAGFQTLE | KIEDMAVSLI | REEWLLDPSQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KDLCRDNRPE | NFRNMFSLGG | ETRSENRELA | SKQVISTGIQ | PHGETAAKCN | GDVIRGLEHE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EARDLLGRLE | RQRGNPTQER | RHKCDECGKS | FAQSSGLVRH | WRIHTGEKPY | QCNVCGKAFS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YRSALLSHQD | IHNKVKRYHC | KECGKAFSQN | TGLILHQRIH | TGEKPYQCNQ | CGKAFSQSAG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LILHQRIHSG | ERPYECNECG | KAFSHSSHLI | GHQRIHTGEK | PYECDECGKT | FRRSSHLIGH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QRSHTGEKPY | KCNECGRAFS | QKSGLIEHQR | IHTGERPYKC | KECGKAFNGN | TGLIQHLRIH |
| 550 | 560 | 570 | |||
| TGEKPYQCNE | CGKAFIQRSS | LIRHQRIHSG | EKSESISV |