AiPD: Autoinhibited Protein Database

Q14185

Gene name	DOCK1
Protein name	Dedicator of cytokinesis protein 1
Names	180 kDa protein downstream of CRK, DOCK180
Species	Homo sapiens (Human)
KEGG Pathway	hsa:1793
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1712-1791 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1712-1791 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

2 structures for Q14185

Entry ID	Method	Resolution	Chain	Position	Source
3L4C	X-ray	237 A	A/B	422-619	PDB
AF-Q14185-F1	Predicted				AlphaFoldDB

1384 variants for Q14185

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs758997336 RCV000624248	148	K>missing	Inborn genetic diseases [ClinVar]	Yes	ClinVar dbSNP
rs767858333 RCV000623431	664	E>missing	Inborn genetic diseases [ClinVar]	Yes	ClinVar dbSNP
CA215753437 rs1036873070	2	T>M		No	ClinGen TOPMed gnomAD
CA378903891 rs867484120	3	R>C		No	ClinGen gnomAD
CA215753438 rs867484120	3	R>S		No	ClinGen gnomAD
rs1187500633 CA378903898	4	W>S		No	ClinGen TOPMed
rs1359555616 CA378903912	6	P>S		No	ClinGen gnomAD
CA5741783 rs768435458	9	R>C		No	ClinGen ExAC TOPMed gnomAD
CA5741786 rs761671652	12	K>R		No	ClinGen ExAC gnomAD
rs1317871657 CA378904237	17	F>I		No	ClinGen TOPMed
rs764444370 CA5741814	20	Y>C		No	ClinGen ExAC gnomAD
CA5741816 rs762217323	23	R>G		No	ClinGen ExAC gnomAD
CA378904287 rs1161315852	23	R>S		No	ClinGen gnomAD
TCGA novel	23	R>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	24	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378904297 rs371087791	25	A>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA5741817 rs371087791	25	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs946779078 CA215759880	29	S>T		No	ClinGen TOPMed
CA215759881 rs1043592156 CA215759882	31	Q>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA378904340 rs1399680843	32	I>V		No	ClinGen gnomAD
rs779548919 CA5741820	33	G>R		No	ClinGen ExAC gnomAD
rs377320265 CA5741821	35	T>A		No	ClinGen ESP ExAC gnomAD
CA215759883 rs937833335	35	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA5741822 rs754574678	37	H>Y		No	ClinGen ExAC gnomAD
rs771891784 CA378904410	42	Y>*		No	ClinGen ExAC TOPMed gnomAD
CA5741824 rs747836571	42	Y>H		No	ClinGen ExAC gnomAD
rs553053974 CA5741842	45	W>*		No	ClinGen 1000Genomes ExAC gnomAD
CA378904451 rs1192719948	46	Y>C		No	ClinGen gnomAD
CA215760685 rs1054479346	47	R>Q		No	ClinGen TOPMed
rs1260759480 CA378904466	49	Y>H		No	ClinGen TOPMed gnomAD
rs757996239 CA5741843	50	T>M		No	ClinGen ExAC TOPMed gnomAD
CA5741845 rs746815750	52	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs757172365 CA5741846	52	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed
CA5741848 rs571267306	53	K>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1377543831 CA378904492	53	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs745842428 CA5741849	54	K>M		No	ClinGen ExAC TOPMed gnomAD
rs745842428 CA378904498	54	K>R		No	ClinGen ExAC TOPMed gnomAD
CA378904497 rs745842428	54	K>T		No	ClinGen ExAC TOPMed gnomAD
rs774630796 CA5741851	56	K>E		No	ClinGen ExAC TOPMed gnomAD
CA378904511 rs1213564881	56	K>R		No	ClinGen TOPMed
CA378904538 rs1467522499	58	G>D		No	ClinGen Ensembl
CA5741879 rs779095586	59	I>L		No	ClinGen ExAC TOPMed gnomAD
CA5741878 rs779095586	59	I>V		No	ClinGen ExAC TOPMed gnomAD
rs772241085 CA5741880	61	P>S		No	ClinGen ExAC gnomAD
rs1025603420 CA215761174	62	A>T		No	ClinGen TOPMed
CA5741881 rs773273898	67	L>P		No	ClinGen ExAC gnomAD
CA5741883 rs771267415	69	E>G		No	ClinGen ExAC TOPMed gnomAD
CA5741884 rs776990526	70	A>V		No	ClinGen ExAC TOPMed gnomAD
CA5741887 rs775018138	71	I>T		No	ClinGen ExAC TOPMed gnomAD
rs199845959 CA5741886	71	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA215761176 rs933923507	72	V>I		No	ClinGen TOPMed
TCGA novel	74	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5741899 rs373898575	77	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA378904693 rs1216288822	79	E>D		No	ClinGen TOPMed
CA378904707 rs1317290044	81	V>A		No	ClinGen gnomAD
rs377023959 CA5741902	83	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA215761895 rs377023959	83	P>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs1309261176 CA378904717	83	P>S		No	ClinGen gnomAD
rs1484796274 CA378904719	84	G>S		No	ClinGen gnomAD
rs979119696 CA215761897	87	P>S		No	ClinGen TOPMed gnomAD
rs1421070388 CA378904746	88	L>F		No	ClinGen gnomAD
rs763584443 CA5741905	89	I>M		No	ClinGen ExAC gnomAD
rs1436243796 CA378904751	89	I>V		No	ClinGen TOPMed gnomAD
rs1172446532 CA378904775	92	V>A		No	ClinGen gnomAD
rs749011141 CA215761898	94	T>A		No	ClinGen gnomAD
rs773928262 CA5741907	94	T>M		No	ClinGen ExAC TOPMed gnomAD
rs770313952 CA5741909	95	T>K		No	ClinGen ExAC TOPMed gnomAD
CA378904800 rs1271816524	97	R>*		No	ClinGen gnomAD
rs1364200071 CA378904801	97	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs750147964 CA5741910	99	W>C		No	ClinGen ExAC gnomAD
TCGA novel	105	Q>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5741914 rs147989604	108	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5741913 rs147989604	108	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1362910752 CA378694183	110	D>G		No	ClinGen gnomAD
TCGA novel	110	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1468279043 CA378694187	111	N>H		No	ClinGen TOPMed gnomAD
CA378694190 rs1157980910	111	N>T		No	ClinGen TOPMed
rs772994764 CA5741929	114	M>I		No	ClinGen ExAC gnomAD
TCGA novel CA5741930 rs760460729	115	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen ExAC gnomAD
rs766026803 CA5741931	116	R>*		No	ClinGen ExAC gnomAD
rs193160639 CA5741932	116	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs1443265553 CA378694229	117	S>G		No	ClinGen gnomAD
CA5741933 rs759349034	118	V>G		No	ClinGen ExAC TOPMed gnomAD
CA215381985 rs973298505	118	V>M		No	ClinGen TOPMed
rs765245181 CA5741934	119	R>G		No	ClinGen ExAC TOPMed gnomAD
CA5741936 rs757300109	119	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs765245181 CA5741935	119	R>W		No	ClinGen ExAC TOPMed gnomAD
CA378694251 rs1330163197	121	M>V		No	ClinGen gnomAD
rs750631429 CA5741938	123	Y>C		No	ClinGen ExAC gnomAD
rs1271767610 CA378694282	125	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA5741939 rs771234802	126	I>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	128	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1213815239 CA378694302	128	W>R		No	ClinGen gnomAD
CA5741940 rs780941985	129	R>*		No	ClinGen ExAC TOPMed gnomAD
rs749695334 CA5741941	129	R>Q		No	ClinGen ExAC gnomAD
CA5741942 rs374693322	130	S>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1233277486 CA378694320	131	Q>*		No	ClinGen gnomAD
CA5741943 rs779529803	134	S>P		No	ClinGen ExAC gnomAD
rs75555086 CA215382057	143	K>R		No	ClinGen Ensembl
rs748731456 CA5741944	144	E>Q		No	ClinGen ExAC gnomAD
rs576434465 CA5741946	147	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA378694432 rs1565037687	148	K>E		No	ClinGen Ensembl
CA378694437 rs1389891826	148	K>N		No	ClinGen gnomAD
rs772859229 CA5741947	151	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA5741948 rs746572428	152	K>R		No	ClinGen ExAC gnomAD
rs770644938 CA5741949	153	I>T		No	ClinGen ExAC gnomAD
rs145105617 CA5741950	155	Y>D		No	ClinGen 1000Genomes ExAC gnomAD
rs759356702 CA5741951	156	G>R		No	ClinGen ExAC gnomAD
rs764984706 CA5741952	156	G>V		No	ClinGen ExAC gnomAD
CA215386709 rs34385401	159	I>V		No	ClinGen Ensembl
CA215386710 rs902631783	160	L>I		No	ClinGen TOPMed gnomAD
TCGA novel	160	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5741980 rs754076353	161	D>G		No	ClinGen ExAC gnomAD
CA5741982 rs765627154	163	D>E		No	ClinGen ExAC gnomAD
rs201203523 CA5741981	163	D>G		No	ClinGen ExAC TOPMed gnomAD
CA5741984 rs758923428	165	V>L		No	ClinGen ExAC gnomAD
rs752049755 CA5741986	167	R>G		No	ClinGen ExAC gnomAD
CA378695336 rs1231667593	167	R>T		No	ClinGen gnomAD
rs756789676 CA5741987	168	D>N		No	ClinGen ExAC gnomAD
rs1486840733 CA378695351	169	E>D		No	ClinGen gnomAD
rs769441289 CA5741990	169	E>G		No	ClinGen ExAC TOPMed gnomAD
rs745471375 CA5741989	169	E>Q		No	ClinGen ExAC gnomAD
CA5741991 rs779785531	170	D>H		No	ClinGen ExAC TOPMed gnomAD
CA378695375 rs1468050372	173	I>V		No	ClinGen gnomAD
rs895703029 CA215386765	177	E>G		No	ClinGen TOPMed
rs1014138360 CA215386772	179	T>A		No	ClinGen TOPMed
CA5741994 rs774339613	179	T>I		No	ClinGen ExAC gnomAD
rs770984148 CA5741996	181	T>M		No	ClinGen ExAC TOPMed gnomAD
CA5741998 rs759788379	183	S>N		No	ClinGen ExAC TOPMed gnomAD
CA5742000 TCGA novel rs765575115	183	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen ExAC TOPMed gnomAD
rs1367828851 CA378695480	188	H>N		No	ClinGen TOPMed
CA5742002 rs764623951	188	H>R		No	ClinGen ExAC gnomAD
rs752097388 CA5742003	189	E>K		No	ClinGen ExAC gnomAD
CA378695495 rs1367951186	190	I>V		No	ClinGen gnomAD
CA5742004 rs757722252	196	E>A		No	ClinGen ExAC gnomAD
rs775644781 CA215386815	196	E>K		No	ClinGen TOPMed
CA378695535 rs775644781	196	E>Q		No	ClinGen TOPMed
CA378695542 rs1318462259	197	E>Q		No	ClinGen gnomAD
rs780686971 CA5742005	198	R>M		No	ClinGen ExAC gnomAD
rs779660796 CA5742008	200	Q>R		No	ClinGen ExAC gnomAD
rs749004671 CA5742009	201	E>K		No	ClinGen ExAC gnomAD
rs540730500 CA5742010	201	E>V		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	202	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378695579 rs1176770110	202	E>Q		No	ClinGen gnomAD
CA378695586 rs1591580246	203	K>E		No	ClinGen Ensembl
rs1030549055 CA215388389	205	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA5742038 rs777538072	205	Q>L		No	ClinGen ExAC gnomAD
rs1331938155 CA378695638	208	N>S		No	ClinGen TOPMed
rs747008222 CA5742039	209	I>T		No	ClinGen ExAC gnomAD
rs1413608392 CA378695652	210	D>G		No	ClinGen TOPMed
CA5742040 rs769983959	211	I>T		No	ClinGen ExAC TOPMed gnomAD
CA378695663 rs1174993446	212	N>D		No	ClinGen TOPMed
CA378695669 rs1312061447	212	N>K		No	ClinGen gnomAD
CA5742041 rs775728846	213	R>K		No	ClinGen ExAC gnomAD
rs749458340 CA5742042	214	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs749458340 CA378695676	214	Q>K		No	ClinGen ExAC TOPMed gnomAD
CA5742043 rs768792329	215	A>G		No	ClinGen ExAC TOPMed gnomAD
CA378695686 rs768792329	215	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs940598949 CA215388458	216	K>E		No	ClinGen TOPMed
CA378695723 rs1414230034	221	P>H		No	ClinGen gnomAD
rs564724729 CA5742046	221	P>S		No	ClinGen 1000Genomes ExAC gnomAD
CA378695740 rs1280071759	224	A>D		No	ClinGen gnomAD
CA378695742 rs1280071759	224	A>V		No	ClinGen gnomAD
CA5742048 rs761182932	228	N>K		No	ClinGen ExAC gnomAD
CA378695768 rs1484867367	228	N>S		No	ClinGen gnomAD
CA215388488 rs764826742	229	L>F		No	ClinGen Ensembl
TCGA novel	231	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	244	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1449699349 CA378695877	244	M>L		No	ClinGen gnomAD
CA378695885 rs1172588978	245	S>A		No	ClinGen gnomAD
rs752430840 CA5742053	247	Y>D		No	ClinGen ExAC gnomAD
rs758095868 CA5742057	249	P>R		No	ClinGen ExAC TOPMed gnomAD
rs758120817 CA215388544	249	P>S		No	ClinGen ExAC TOPMed gnomAD
rs758120817 CA5742056	249	P>T		No	ClinGen ExAC TOPMed gnomAD
CA378695937 rs1303011286	253	K>R		No	ClinGen TOPMed gnomAD
rs140799120 CA5742060	255	I>F		No	ClinGen 1000Genomes ExAC gnomAD
CA378695990 CA5742080 rs370347429	258	N>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs1468453242 CA378695995	259	Y>C		No	ClinGen gnomAD
rs765924730 CA5742081	262	R>C		No	ClinGen ExAC TOPMed gnomAD
rs748248819 CA5742082	262	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs748248819 CA378696013	262	R>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	262	R>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378696030 rs778059635	265	S>C		No	ClinGen ExAC gnomAD
rs778059635 CA5742084	265	S>G		No	ClinGen ExAC gnomAD
CA5742088 CA378696077 rs777117151	272	I>L		No	ClinGen ExAC TOPMed gnomAD
rs373741100 CA378696105	276	H>N		No	ClinGen ESP ExAC gnomAD
CA378696108 rs1420239654	276	H>R		No	ClinGen TOPMed
CA5742089 rs373741100	276	H>Y		No	ClinGen ESP ExAC gnomAD
CA378696117 rs1591591284	277	N>I		No	ClinGen Ensembl
TCGA novel	278	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1591591295 CA378696122	278	L>W		No	ClinGen Ensembl
CA378696127 rs769129811	279	R>*		No	ClinGen ExAC TOPMed gnomAD
CA5742090 rs769129811	279	R>G		No	ClinGen ExAC TOPMed gnomAD
CA378696131 rs1357802190	280	A>T		No	ClinGen gnomAD
rs371112922 CA215389851	281	V>M		No	ClinGen ESP gnomAD
rs761618116 CA5742112	284	D>G		No	ClinGen ExAC gnomAD
CA378696214 rs1278248565	284	D>N		No	ClinGen TOPMed
rs773087863 CA5742114	286	G>A		No	ClinGen ExAC gnomAD
rs1447893528 CA378696243	286	G>R		No	ClinGen gnomAD
TCGA novel	292	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378696329 rs1235056841	292	R>K		No	ClinGen TOPMed
CA378696344 rs1405054529	293	E>G		No	ClinGen gnomAD
rs187171084 CA215390659	293	E>K		No	ClinGen 1000Genomes
CA5742116 rs141906544	297	F>S		No	ClinGen 1000Genomes ExAC gnomAD
rs753758508 CA5742117	299	C>G		No	ClinGen ExAC gnomAD
CA215390682 rs906422235	303	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA5742118 rs758467730	303	R>H		No	ClinGen ExAC TOPMed gnomAD
CA5742121 rs140885933	304	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs374946985 CA5742122	306	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs746267114 CA5742123	306	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed
rs756484607 CA5742124	307	M>V		No	ClinGen ExAC
CA378696562 rs1363567975	310	R>K		No	ClinGen TOPMed
CA378696585 rs1248951294	312	N>D		No	ClinGen gnomAD
CA378696592 rs1453982412	312	N>S		No	ClinGen gnomAD
CA378696611 rs1467028318	313	N>K		No	ClinGen TOPMed gnomAD
rs200363456 CA5742127	313	N>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1591594258 CA378696659	317	L>P		No	ClinGen Ensembl
rs768270400 CA5742128	319	S>L		No	ClinGen ExAC TOPMed gnomAD
CA378696697 rs1264838643	321	L>M		No	ClinGen gnomAD
CA5742131 rs771775279	322	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA5742132 rs772785460	323	R>*		No	ClinGen ExAC gnomAD
rs772785460 CA5742133	323	R>G		No	ClinGen ExAC gnomAD
CA5742134 rs563537294	323	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs776616886 CA5742135	329	V>M		No	ClinGen ExAC gnomAD
TCGA novel	331	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1289100385 CA378696908	332	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1219429703 CA378696920	334	D>N		No	ClinGen gnomAD
CA378696929 rs1247536525	335	I>L		No	ClinGen TOPMed
rs746697217 CA5742153	335	I>T		No	ClinGen ExAC TOPMed gnomAD
CA378696946 rs1204972110	337	N>I		No	ClinGen gnomAD
CA378696945 rs1204972110	337	N>S		No	ClinGen gnomAD
CA5742155 rs556342533	341	D>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1473863313 CA378696998	344	D>E		No	ClinGen gnomAD
rs1412472477 CA378697031	348	F>L		No	ClinGen gnomAD
rs1421595320 CA378697033	349	I>F		No	ClinGen gnomAD
CA378697047 rs1166254775	351	F>V		No	ClinGen gnomAD
CA215399335 rs560821920	352	Q>K		No	ClinGen Ensembl
rs1350178554 CA378697060	353	P>S		No	ClinGen gnomAD
CA378697239 rs1591641610	354	V>G		No	ClinGen Ensembl
CA378697233 rs1244790249	354	V>L		No	ClinGen gnomAD
CA378697231 rs1244790249	354	V>M		No	ClinGen gnomAD
CA378697270 rs1478917155	357	E>*		No	ClinGen gnomAD
rs746080157 CA215402324	357	E>D		No	ClinGen gnomAD
CA5742198 rs200993205	362	Q>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA215402339 rs367857182	363	T>I		No	ClinGen ESP TOPMed
CA378697378 rs1565062863	365	I>T		No	ClinGen Ensembl
rs576201052 CA215402343	369	I>V		No	ClinGen gnomAD
rs543157521 CA5742200	370	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1049921083 CA215402359	371	A>D		No	ClinGen Ensembl
CA215402352 rs995256286	371	A>T		No	ClinGen Ensembl
CA378697469 rs1591641797	374	V>I		No	ClinGen Ensembl
rs374940596 CA5742201	375	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1348327633 CA378697525	377	K>N		No	ClinGen gnomAD
rs1478307594 CA378697518	377	K>R		No	ClinGen TOPMed
CA378697856 rs199995435	381	L>F		No	ClinGen ExAC TOPMed gnomAD
CA378697861 rs1373096449	382	W>*		No	ClinGen TOPMed
CA378697876 rs1306912748	384	T>I		No	ClinGen TOPMed
rs749969211 CA5742225	385	L>F		No	ClinGen ExAC gnomAD
rs760275463 CA5742226	387	L>V		No	ClinGen ExAC gnomAD
CA378697899 rs1206994380	388	L>I		No	ClinGen gnomAD
CA378697906 rs1252534780	389	P>S		No	ClinGen TOPMed gnomAD
CA5742227 rs765913843	391	D>V		No	ClinGen ExAC
rs778778518 CA5742230	392	I>M		No	ClinGen ExAC gnomAD
CA5742229 rs754712267	392	I>T		No	ClinGen ExAC TOPMed gnomAD
rs753590775 CA5742228	392	I>V		No	ClinGen ExAC gnomAD
CA5742231 rs752509827	396	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA378697952 rs1389761562	396	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA378697959 rs1374460922	397	K>R		No	ClinGen TOPMed
rs368944664 CA5742235	400	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1158959302 CA378697999	403	V>M		No	ClinGen TOPMed
TCGA novel	405	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	408	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs372560858 CA5742238	408	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs751481585 CA215408902	409	V>L		No	ClinGen gnomAD
TCGA novel	411	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5742239 rs774786886	411	R>P		No	ClinGen ExAC TOPMed
rs772592699 CA5742241	413	T>K		No	ClinGen ExAC gnomAD
CA215408937 rs1016113106	415	F>V		No	ClinGen gnomAD
CA5742242 rs773745149	416	P>L		No	ClinGen ExAC gnomAD
CA5742269 rs757225154	422	G>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5742270 rs766333447	424	V>I		No	ClinGen ExAC gnomAD
TCGA novel	427	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1227645266 CA378698176	428	I>T		No	ClinGen gnomAD
CA5742271 rs753975651	429	Y>C		No	ClinGen ExAC gnomAD
CA378698179 rs1311909304	429	Y>H		No	ClinGen TOPMed
rs779079768 CA5742273	430	V>A		No	ClinGen ExAC TOPMed gnomAD
rs529958746 CA5742274	431	T>A		No	ClinGen 1000Genomes ExAC gnomAD
CA5742276 rs778112893	431	T>I		No	ClinGen ExAC gnomAD
TCGA novel	431	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs529958746 CA5742275	431	T>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1208440375 CA378698196	432	L>S		No	ClinGen TOPMed gnomAD
rs747473475 CA5742277	434	Q>*		No	ClinGen ExAC gnomAD
CA215418317 rs753729676	434	Q>R		No	ClinGen Ensembl
CA378698215 rs1490665080	435	G>E		No	ClinGen gnomAD
CA378698213 rs1467671398	435	G>R		No	ClinGen TOPMed
CA5742278 rs374932663	436	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA378698249 rs1410365816	440	G>R		No	ClinGen gnomAD
rs1473310885 CA378698258	441	S>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA378698267 rs1399975788	442	K>R		No	ClinGen TOPMed
CA5742280 rs745351794	445	A>V		No	ClinGen ExAC gnomAD
CA215418337 rs910579337	446	K>N		No	ClinGen TOPMed gnomAD
rs1409161195 CA378698303	448	V>M		No	ClinGen gnomAD
CA378698324 rs1288568021	451	T>A		No	ClinGen gnomAD
rs551125851 CA5742283	451	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1225590018 CA378698329	452	V>L		No	ClinGen gnomAD
CA5742286 rs761609326	455	Y>C		No	ClinGen ExAC gnomAD
TCGA novel	455	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1294429988 CA378698353	456	D>N		No	ClinGen TOPMed gnomAD
rs1204850631 CA378698374	458	D>V		No	ClinGen gnomAD
TCGA novel	460	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5742289 rs755068207	461	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs765309599 CA5742290	461	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA5742291 rs372790668	462	L>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs200316381 CA378698421	464	H>D		No	ClinGen gnomAD
rs764269961 CA5742310	464	H>L		No	ClinGen ExAC TOPMed gnomAD
rs200316381 CA215419627	464	H>Y		No	ClinGen gnomAD
rs1338767837 CA378698428	465	V>M		No	ClinGen gnomAD
TCGA novel	466	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5742311 rs201991461	468	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1434561401 CA378698449	468	P>S		No	ClinGen TOPMed gnomAD
CA378698453 rs1215503619	469	G>R		No	ClinGen gnomAD
CA5742314 rs374761788	470	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1360356480 CA378698463	471	G>S		No	ClinGen TOPMed
CA5742315 rs756721903	473	E>K		No	ClinGen ExAC gnomAD
CA5742316 rs779665451	474	A>V		No	ClinGen ExAC TOPMed gnomAD
CA378698499 rs1388879817	476	S>*		No	ClinGen TOPMed
TCGA novel	478	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1564741478 CA378698519	479	K>E		No	ClinGen Ensembl
CA5742321 rs771828391	479	K>R		No	ClinGen ExAC TOPMed gnomAD
CA5742322 rs771828391	479	K>T		No	ClinGen ExAC TOPMed gnomAD
rs1190403810 CA378698532	481	V>M		No	ClinGen TOPMed gnomAD
rs760609272 CA5742323	482	I>V		No	ClinGen ExAC gnomAD
rs1481344953 CA378698567	486	V>L		No	ClinGen gnomAD
rs373413868 CA5742324	489	P>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs373413868 CA378698589	489	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA378698594 rs1456939677	490	R>C		No	ClinGen TOPMed gnomAD
rs776589124 CA378698596	490	R>H		No	ClinGen ExAC gnomAD
CA5742325 rs776589124	490	R>L		No	ClinGen ExAC gnomAD
rs763016476 CA5742327	495	V>F		No	ClinGen ExAC gnomAD
rs907467357 CA215419694	496	K>E		No	ClinGen TOPMed
CA5742328 rs544408185	496	K>T		No	ClinGen 1000Genomes ExAC gnomAD
CA378698825 rs1179750735	497	V>M		No	ClinGen gnomAD
rs868221807 CA215421438	498	A>D		No	ClinGen TOPMed
CA378698831 rs1470645685	498	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs868221807 CA215421439	498	A>V		No	ClinGen TOPMed
CA378698854 rs1162617739	500	P>S		No	ClinGen TOPMed
CA378698865 rs1427018541	501	I>F		No	ClinGen gnomAD
rs1370503320 CA378698875	502	E>K		No	ClinGen gnomAD
rs768714380 CA5742347	504	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs762048054 CA5742349	506	R>C		No	ClinGen ExAC TOPMed gnomAD
CA5742350 rs150790785	506	R>H	Variant assessed as Somatic; 0.0003247 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs150790785 CA378698942	506	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA215421489 rs762048054	506	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1384540848 CA378698949	507	S>C		No	ClinGen gnomAD
CA5742351 rs773525849	507	S>T		No	ClinGen ExAC gnomAD
rs1340008027 CA378698996	510	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA378698992 rs1273560968	510	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA378699000 rs1273598919	511	F>L		No	ClinGen gnomAD
CA5742353 rs200582355	512	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs201574191 CA5742354	514	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs754326476 CA215421550	514	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs754326476 CA5742355	514	R>L		No	ClinGen ExAC TOPMed gnomAD
rs1392368693 CA378699048	515	H>Y		No	ClinGen TOPMed
TCGA novel	519	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215426618 rs920079674	522	K>R		No	ClinGen gnomAD
CA378700526 rs1178355665	523	D>N		No	ClinGen TOPMed
TCGA novel	523	D>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs931618115 CA215426622	524	K>R		No	ClinGen Ensembl
CA378700557 rs1224167905	525	S>T		No	ClinGen gnomAD
rs1260433091 CA378700606	528	I>T		No	ClinGen TOPMed gnomAD
CA5742378 rs765628505	533	F>C		No	ClinGen ExAC gnomAD
CA5742379 rs753313500	537	M>I		No	ClinGen ExAC gnomAD
rs1208161011 CA378700744	539	Y>C		No	ClinGen TOPMed
rs1490335008 CA378700753	540	D>N		No	ClinGen TOPMed gnomAD
CA378700845 rs1591745470	546	D>G		No	ClinGen Ensembl
CA5742386 rs755980419	547	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1057180572 CA215426699	550	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA5742389 rs771991452	552	I>T		No	ClinGen ExAC gnomAD
rs535572784 CA5742391	553	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA5742393 rs373756074	554	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs373756074 CA5742392	554	Y>S		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	555	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378701035 rs1242213957	556	A>T		No	ClinGen gnomAD
CA378701051 rs1185208689	557	E>K		No	ClinGen gnomAD
CA5742419 rs761310036	558	A>G		No	ClinGen ExAC gnomAD
CA378701173 rs1591747447	563	D>V		No	ClinGen Ensembl
rs1591747467 CA378701200	564	A>V		No	ClinGen Ensembl
rs1356201975 CA378701211	565	A>S		No	ClinGen TOPMed gnomAD
CA378701203 rs1356201975	565	A>T		No	ClinGen TOPMed gnomAD
CA5742423 rs766035033	566	T>M		No	ClinGen ExAC TOPMed gnomAD
rs746067129 CA215427286	568	L>F		No	ClinGen Ensembl
rs1253401024 CA378701285	569	S>I		No	ClinGen TOPMed
rs1403065120 CA378701278	569	S>R		No	ClinGen gnomAD
rs754857756 CA5742425	571	P>L		No	ClinGen ExAC gnomAD
rs1384057049 CA378701353	573	T>A		No	ClinGen gnomAD
CA5742427 rs372005171	573	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	576	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1463359784 CA378701472	579	E>A		No	ClinGen TOPMed gnomAD
CA378701464 rs1309768528	579	E>K		No	ClinGen gnomAD
rs1204626691 CA378701507	581	G>V		No	ClinGen gnomAD
CA5742429 rs781425786	582	H>R		No	ClinGen ExAC gnomAD
CA5742430 rs368083273	583	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs754821075 CA215427374	583	S>T		No	ClinGen TOPMed gnomAD
rs756381755 CA5742431	584	A>D		No	ClinGen ExAC gnomAD
rs1306167561 CA378701570	586	G>A		No	ClinGen TOPMed
CA378701564 rs749635446	586	G>C		No	ClinGen ExAC TOPMed gnomAD
rs749635446 CA5742433	586	G>S		No	ClinGen ExAC TOPMed gnomAD
CA378701626 rs769077651 CA5742434	589	M>I		No	ClinGen ExAC TOPMed gnomAD
CA378701620 rs1428623506	589	M>T		No	ClinGen gnomAD
CA378701614 rs1171513306	589	M>V		No	ClinGen gnomAD
rs1332274941 CA378701633	590	Q>*		No	ClinGen TOPMed
CA378701688 rs1436539401	592	L>P		No	ClinGen gnomAD
CA378701700 rs1338989712	593	G>E		No	ClinGen gnomAD
CA378701710 rs1407109652	594	S>N		No	ClinGen gnomAD
rs748671173 CA5742436	595	C>F		No	ClinGen ExAC gnomAD
rs774829252 CA5742435	595	C>G		No	ClinGen ExAC TOPMed gnomAD
rs774829252 CA378701718	595	C>R		No	ClinGen ExAC TOPMed gnomAD
rs748671173 CA378701724	595	C>Y		No	ClinGen ExAC gnomAD
rs1591747990 CA378701739	596	T>I		No	ClinGen Ensembl
CA5742439 rs760148261	597	I>T		No	ClinGen ExAC gnomAD
rs375864195 CA5742438	597	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA378701761 rs1465498890	598	S>G		No	ClinGen TOPMed
CA215427433 rs540708875	598	S>T		No	ClinGen Ensembl
rs1591748093 CA378701822	601	S>F		No	ClinGen Ensembl
CA5742441 rs776210962	604	I>F		No	ClinGen ExAC gnomAD
CA215427467 rs566255432	605	S>F		No	ClinGen TOPMed gnomAD
CA5742443 rs765135339	605	S>P		No	ClinGen ExAC gnomAD
CA378701876 rs566255432	605	S>Y		No	ClinGen TOPMed gnomAD
CA5742444 rs752613726	606	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	607	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5742447 rs750494984	608	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1426153607 CA378701924	609	C>W		No	ClinGen gnomAD
CA215427485 rs924154879	612	K>R		No	ClinGen TOPMed gnomAD
CA215427490 rs868796008	615	Q>K		No	ClinGen Ensembl
rs1347271770 CA378702023	617	V>M		No	ClinGen gnomAD
rs372475096 CA5742465	622	L>F		No	ClinGen ESP ExAC gnomAD
CA378702895 rs1357885669	622	L>P		No	ClinGen TOPMed gnomAD
CA378702922 rs1407424333	626	R>C		No	ClinGen TOPMed
CA5742467 rs753998108	626	R>H		No	ClinGen ExAC TOPMed gnomAD
rs755211550 CA5742468	627	S>F		No	ClinGen ExAC gnomAD
CA5742469 rs566128248	628	N>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA378702938 rs1591768418	629	T>P		No	ClinGen Ensembl
rs959880312 CA215432610	630	S>T		No	ClinGen TOPMed
CA5742470 rs753042267	634	Q>*		No	ClinGen ExAC gnomAD
CA378703003 rs1451414779	638	Q>R		No	ClinGen gnomAD
rs540128098 CA378703025 CA378703026	641	K>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs747478024 CA5742473	641	K>R		No	ClinGen ExAC TOPMed gnomAD
CA378703027 rs1337297926	642	V>I		No	ClinGen gnomAD
rs745478937 CA5742477	643	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5742478 rs769540835	644	G>D		No	ClinGen ExAC gnomAD
TCGA novel	644	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378703067 rs1304946826	648	V>L		No	ClinGen TOPMed
CA378703366 rs1466192762	650	F>Y		No	ClinGen gnomAD
CA378703461 rs1382571749	657	A>V		No	ClinGen gnomAD
rs748075720 CA5742511	659	F>L		No	ClinGen ExAC gnomAD
rs758242756 CA215436549	660	N>S		No	ClinGen TOPMed
rs771868772 CA5742513	663	M>K		No	ClinGen ExAC
rs773196502 CA5742514	665	N>H		No	ClinGen ExAC TOPMed gnomAD
rs773196502 CA378703543	665	N>Y		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	667	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378703584 rs1343423456	668	S>N		No	ClinGen TOPMed
rs759611299 CA5742516	669	E>K		No	ClinGen ExAC TOPMed gnomAD
rs765309183 CA5742517	672	D>E		No	ClinGen ExAC gnomAD
rs775635038 CA5742518	673	T>M		No	ClinGen ExAC gnomAD
rs1314185345 CA378703646	673	T>P		No	ClinGen gnomAD
CA378703700 rs1219227153	677	D>G		No	ClinGen TOPMed gnomAD
rs1219227153 CA378703701	677	D>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1287441421 CA378703706	678	A>P		No	ClinGen gnomAD
CA378703707 rs1287441421	678	A>S		No	ClinGen gnomAD
TCGA novel	680	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215436903 rs968353366	682	I>T		No	ClinGen TOPMed gnomAD
rs775579849 CA5742535	682	I>V		No	ClinGen ExAC TOPMed gnomAD
CA5742537 rs764200154	684	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1384335317 CA378703823	685	L>M		No	ClinGen gnomAD
rs774692785 CA5742538	686	I>T		No	ClinGen ExAC gnomAD
TCGA novel	691	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1350380468 CA378703918	693	H>Y		No	ClinGen gnomAD
CA5742540 rs767998082	700	T>A		No	ClinGen ExAC TOPMed gnomAD
CA5742541 rs750900337	702	I>V		No	ClinGen ExAC gnomAD
TCGA novel	706	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378704031 rs1382568334	708	A>V		No	ClinGen gnomAD
CA5742544 rs753252079	709	T>M		No	ClinGen ExAC TOPMed gnomAD
rs778430296 CA5742546	710	L>F		No	ClinGen ExAC gnomAD
rs1226075729 CA378704045	711	A>S		No	ClinGen gnomAD
TCGA novel	711	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378704062 rs1249062472	713	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA215443296 rs933090160	717	K>E		No	ClinGen TOPMed
CA5742564 rs534778303	717	K>N		No	ClinGen 1000Genomes ExAC gnomAD
CA5742563 rs754439781	717	K>T		No	ClinGen ExAC gnomAD
TCGA novel	718	V>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378704699 rs1470106864	720	K>R		No	ClinGen TOPMed
CA378704721 rs1380330832	721	N>K		No	ClinGen TOPMed
CA5742567 rs758080614	725	G>D		No	ClinGen ExAC TOPMed gnomAD
CA5742566 rs752245963	725	G>S		No	ClinGen ExAC gnomAD
CA5742569 rs751334535	726	A>G		No	ClinGen ExAC gnomAD
rs777443663 CA5742568	726	A>T		No	ClinGen ExAC gnomAD
rs1171394109 CA378704795	728	K>R		No	ClinGen gnomAD
CA5742570 rs757101826	729	P>L		No	ClinGen ExAC TOPMed gnomAD
rs1202352194 CA378704802	729	P>T		No	ClinGen gnomAD
CA5742571 rs780986950	732	N>T		No	ClinGen ExAC gnomAD
rs932040229 CA215443352	733	E>D		No	ClinGen Ensembl
rs372221636 CA5742573	733	E>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs745821655 CA5742572	733	E>K		No	ClinGen ExAC gnomAD
rs372221636 CA5742574	733	E>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA5742575 rs199584647	738	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA5742577 rs773612844	739	M>I		No	ClinGen ExAC TOPMed gnomAD
rs772389830 CA5742576	739	M>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	740	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378704902 rs765597446	741	A>E		No	ClinGen gnomAD
CA215443368 rs765597446	741	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA5742580 rs776949839	745	I>V		No	ClinGen ExAC gnomAD
CA378704933 rs1213382070	746	F>C		No	ClinGen gnomAD
CA5742581 rs760112759	746	F>V		No	ClinGen ExAC
rs1288084617 CA378704939	747	K>T		No	ClinGen gnomAD
CA378704951 rs1488543680	748	F>L		No	ClinGen gnomAD
CA5742582 rs558883419	749	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs902914475 CA378704959	750	V>L		No	ClinGen TOPMed gnomAD
rs902914475 CA215443399	750	V>M		No	ClinGen TOPMed gnomAD
CA215443404 rs999910753	751	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	752	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs752173506 CA5742583	754	I>N		No	ClinGen ExAC gnomAD
CA378705000 rs1363016393	757	N>H		No	ClinGen gnomAD
rs200247221 CA5742587	757	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	758	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	758	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1303046238 CA378705011	758	Q>R		No	ClinGen gnomAD
TCGA novel	762	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378694859 rs1458547725	765	E>K		No	ClinGen gnomAD
rs1367250635 CA378694874	767	D>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1367250635 CA378694873	767	D>N		No	ClinGen TOPMed gnomAD
CA5742607 rs565353780	769	V>L		No	ClinGen 1000Genomes ExAC gnomAD
rs565353780 CA5742606	769	V>M		No	ClinGen 1000Genomes ExAC gnomAD
rs753889992 CA378694898	770	E>D		No	ClinGen ExAC TOPMed gnomAD
CA5742608 rs376380186	770	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs373010349 CA5742610	776	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA378694934 rs1400567493	776	F>S		No	ClinGen gnomAD
rs778026459 CA5742611	777	R>G		No	ClinGen ExAC gnomAD
rs377325661 CA5742613	780	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs370953579 CA5742614	780	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1317440231 CA378694973	782	M>V		No	ClinGen TOPMed gnomAD
CA378695012 rs1260244336	786	M>I		No	ClinGen gnomAD
CA378695008 rs1216873725	786	M>L		No	ClinGen gnomAD
CA378695007 rs1216873725	786	M>V		No	ClinGen gnomAD
CA5742616 rs374649102	787	S>P		No	ClinGen ESP ExAC gnomAD
CA378695029 rs1203458725	789	Q>E		No	ClinGen gnomAD
rs933649201 CA215393295	789	Q>H		No	ClinGen TOPMed gnomAD
CA378695032 rs1254462018	789	Q>R		No	ClinGen gnomAD
rs1188908215 CA378695040	790	T>S		No	ClinGen gnomAD
rs749808299 CA5742618	791	V>I		No	ClinGen ExAC TOPMed gnomAD
CA378695047 rs1423910041	792	R>Q		No	ClinGen TOPMed gnomAD
CA5742619 rs768105994	792	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1170622824 CA378695060	794	K>R		No	ClinGen gnomAD
rs201249300 CA5742639 CA378700003	795	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs371126639 CA5742640	796	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA5742641 rs771545500	797	A>S		No	ClinGen ExAC TOPMed gnomAD
CA5742643 rs375666837	800	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs1384528233 CA378700122	802	P>L		No	ClinGen gnomAD
CA378700114 rs1159242265	802	P>T		No	ClinGen TOPMed gnomAD
rs199851857 CA5742644	803	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5742645 rs373968953	803	T>M	Variant assessed as Somatic; 4.996e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs201701102 CA215425068	805	V>I		No	ClinGen TOPMed gnomAD
rs1310640476 CA378700181	806	N>S		No	ClinGen gnomAD
rs924140488 CA215425073	806	N>Y		No	ClinGen Ensembl
rs767508399 CA5742650	807	D>H		No	ClinGen ExAC gnomAD
CA378700210 rs1266655656	808	V>M		No	ClinGen gnomAD
TCGA novel	811	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs750609368 CA5742651	812	F>L		No	ClinGen ExAC TOPMed gnomAD
CA215425081 rs935399816	813	D>G		No	ClinGen Ensembl
rs756360164 CA5742652	813	D>H		No	ClinGen ExAC gnomAD
TCGA novel	813	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1241224348 CA378700334	815	K>R		No	ClinGen TOPMed
CA378700359 rs1255402162	816	E>D		No	ClinGen gnomAD
rs1338820027 CA378700343	816	E>K		No	ClinGen TOPMed
CA378700364 rs1421935688	817	L>V		No	ClinGen TOPMed gnomAD
CA378702224 rs1310276141	820	M>T		No	ClinGen gnomAD
rs184254832 CA5742678	820	M>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs756894483 CA5742679	821	F>C		No	ClinGen ExAC gnomAD
rs2379163 CA215427712	821	F>I		No	ClinGen Ensembl
rs1461914120 CA378702250	821	F>L		No	ClinGen TOPMed
rs921062915 CA215427722	822	T>S		No	ClinGen Ensembl
rs780925155 CA5742681	825	I>T		No	ClinGen ExAC gnomAD
CA5742682 rs61758436	827	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1187388499 CA378702362	829	P>S		No	ClinGen gnomAD
CA215427782 rs912296017	830	M>L		No	ClinGen TOPMed gnomAD
rs749146009 CA5742685	830	M>T		No	ClinGen ExAC gnomAD
rs565727397 CA378702505	835	I>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1311332438 CA378702496	835	I>S		No	ClinGen TOPMed
rs760735470 CA5742688	835	I>V		No	ClinGen ExAC TOPMed gnomAD
CA5742690 rs776773235	836	Q>R		No	ClinGen ExAC gnomAD
CA5742691 rs759788937	837	K>T		No	ClinGen ExAC gnomAD
rs1220764621 CA378702558	838	L>F		No	ClinGen gnomAD
TCGA novel	840	C>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765539210 CA5742692	840	C>S		No	ClinGen ExAC gnomAD
CA5742694 rs752986153	842	I>M		No	ClinGen ExAC TOPMed gnomAD
rs764504730 CA5742695	843	E>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA5742697 rs369209061	845	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs780873777 CA5742698	846	H>R		No	ClinGen ExAC gnomAD
rs769284782 CA215427854	850	F>L		No	ClinGen Ensembl
CA5742700 rs755690198	852	Q>L		No	ClinGen ExAC gnomAD
CA378702824 rs755690198	852	Q>R		No	ClinGen ExAC gnomAD
rs376145835	853	H>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs140948917 CA5742701	853	H>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs376519025 CA5742721	854	D>V		No	ClinGen ESP ExAC gnomAD
CA5742722 rs747980358	855	C>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	857	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	858	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1480875553 CA378694541	858	I>V		No	ClinGen TOPMed
CA378694554 rs1377138637	860	L>F		No	ClinGen gnomAD
CA378694557 rs1592122602	860	L>R		No	ClinGen Ensembl
CA5742723 rs771978308	861	P>L		No	ClinGen ExAC gnomAD
TCGA novel	862	M>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745935203 CA5742725	862	M>V		No	ClinGen ExAC gnomAD
CA378694583 rs61733299	864	T>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs61733299 CA5742726	864	T>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs763260338 CA5742728	865	D>H		No	ClinGen ExAC gnomAD
CA215419404 rs367890029	865	D>V		No	ClinGen ESP
CA378694585 rs763260338	865	D>Y		No	ClinGen ExAC gnomAD
CA378694609 rs1473496748	868	K>R		No	ClinGen gnomAD
rs562575974 CA215419430	874	Q>P		No	ClinGen 1000Genomes
rs751037501 CA5742733	875	E>K		No	ClinGen ExAC gnomAD
rs988131523 CA215419440	876	D>N		No	ClinGen gnomAD
CA378694672 rs1413687539	877	L>Q		No	ClinGen gnomAD
rs780385884 CA5742734	881	C>S		No	ClinGen ExAC gnomAD
rs765922744 CA378694730	885	S>R		No	ClinGen ExAC TOPMed gnomAD
rs1416712859 CA378694731	886	H>N		No	ClinGen gnomAD
CA5742737 rs753380712	887	I>M		No	ClinGen ExAC
rs747520696 CA5742740	893	R>G		No	ClinGen ExAC TOPMed gnomAD
CA5742741 rs769237090	893	R>K		No	ClinGen ExAC TOPMed gnomAD
CA215419505 rs575962615	896	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs575962615 CA5742743	896	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs540787166 CA5742763	897	G>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA5742764 rs370003810	899	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs370003810 CA378695087	899	T>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1417956801 CA378695110	902	H>R		No	ClinGen gnomAD
rs1161613892 CA378695108	902	H>Y		No	ClinGen TOPMed
rs201486952 CA5742766	903	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs755175575 CA5742767	904	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs779210116 CA5742768	905	I>M		No	ClinGen ExAC gnomAD
CA5742769 rs748390399	906	I>V		No	ClinGen ExAC gnomAD
CA5742771 rs773654503	907	M>I		No	ClinGen ExAC gnomAD
rs199604643 CA5742770	907	M>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA378695188 rs1193178625	909	K>N		No	ClinGen TOPMed
rs1288540444 CA378695190	910	L>I		No	ClinGen TOPMed
rs1352072213 CA378695198	911	L>F		No	ClinGen gnomAD
rs1352072213 CA378695196	911	L>I		No	ClinGen gnomAD
CA378695203 rs1260759936	912	R>Q		No	ClinGen gnomAD
CA5742772 rs747371637	912	R>W		No	ClinGen ExAC gnomAD
CA378695206 rs1220944266	913	T>S		No	ClinGen TOPMed
rs777074727 CA5742774	914	V>M		No	ClinGen ExAC TOPMed gnomAD
CA5742775 rs564483519	916	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA5742777 rs200822411	918	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA5742779 rs763777130 CA378695259	921	M>I		No	ClinGen ExAC gnomAD
rs751349226 CA5742780	922	G>R		No	ClinGen ExAC gnomAD
rs1364506709 CA378695267	923	R>*		No	ClinGen gnomAD
CA5742782 rs376227113	925	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	927	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs750331091 CA5742783	928	I>T		No	ClinGen ExAC gnomAD
TCGA novel	929	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	929	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215468613 rs908098532	930	N>Y		No	ClinGen Ensembl
CA5743246 rs772236426	931	F>L		No	ClinGen ExAC TOPMed gnomAD
CA5743248 rs761014552	932	V>L		No	ClinGen ExAC gnomAD
rs76861764 CA5743250	934	C>F		No	ClinGen ExAC gnomAD
rs759069075 CA5743252	935	M>I		No	ClinGen ExAC gnomAD
CA378704312 rs1228123616	935	M>V		No	ClinGen gnomAD
TCGA novel	936	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1249580664 CA378704325	937	A>T		No	ClinGen TOPMed
rs552636749 CA5743254	938	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA5743255 rs758055664	940	R>*		No	ClinGen ExAC gnomAD
rs571040090 CA378704346	940	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs571040090 CA5743256	940	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1192580730 CA378704353	941	Q>H		No	ClinGen TOPMed gnomAD
rs757013446 CA5743258	943	E>D		No	ClinGen ExAC
rs538234861 CA5743257	943	E>K		No	ClinGen 1000Genomes ExAC gnomAD
rs781055542 CA5743259	947	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA5743260 rs745832837	948	A>T		No	ClinGen ExAC TOPMed gnomAD
CA378704406 rs1413875006	948	A>V		No	ClinGen gnomAD
rs1163988403 CA378704419	950	L>F		No	ClinGen gnomAD
rs756081289 CA5743261	950	L>V		No	ClinGen ExAC gnomAD
rs1379341893 CA378704422	951	I>V		No	ClinGen Ensembl
CA5743262 rs778946818	952	K>R		No	ClinGen ExAC gnomAD
CA5743263 rs748238377	953	T>I		No	ClinGen ExAC gnomAD
CA378704451 rs1383037723	955	G>E		No	ClinGen gnomAD
rs1305219249 CA378704449	955	G>R		No	ClinGen gnomAD
CA215468750 rs916062123	958	R>T		No	ClinGen TOPMed gnomAD
rs772337291 CA5743264	959	T>A		No	ClinGen ExAC TOPMed gnomAD
rs773312920 CA5743266	959	T>I		No	ClinGen ExAC TOPMed gnomAD
CA5743265 rs773312920	959	T>S		No	ClinGen ExAC TOPMed gnomAD
rs772337291 CA215468784	959	T>S		No	ClinGen ExAC TOPMed gnomAD
CA378704481 rs1173349146	960	D>Y		No	ClinGen TOPMed
CA5743268 rs777238665	961	V>M		No	ClinGen ExAC gnomAD
rs760088702 CA5743269	962	V>I		No	ClinGen ExAC TOPMed gnomAD
rs760088702 CA5743270	962	V>L		No	ClinGen ExAC TOPMed gnomAD
CA5743286 rs781679502	963	D>E		No	ClinGen ExAC gnomAD
CA5743285 rs771319631	963	D>Y		No	ClinGen ExAC gnomAD
CA378904024 rs1333982113	967	E>K		No	ClinGen gnomAD
CA5743288 rs770357047	968	T>A		No	ClinGen ExAC gnomAD
CA215762781 rs1009239241	969	F>L		No	ClinGen TOPMed
TCGA novel	970	I>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378904055 rs1337890337	971	M>T		No	ClinGen gnomAD
CA5743290 rs762473066	973	K>E		No	ClinGen ExAC gnomAD
CA5743291 rs762473066	973	K>Q		No	ClinGen ExAC gnomAD
CA5743292 rs773948788	978	K>Q		No	ClinGen ExAC gnomAD
CA215762783 rs922456430	980	V>I		No	ClinGen TOPMed gnomAD
CA378904125 rs1313661034	981	Y>C		No	ClinGen gnomAD
rs1247285295 CA378904143	984	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1247285295 CA378904145	984	D>Y		No	ClinGen gnomAD
rs750218824 CA5743296	986	V>M		No	ClinGen ExAC gnomAD
CA378904171 rs1243900750	987	I>M		No	ClinGen gnomAD
rs777306228 CA215762784	988	M>V		No	ClinGen Ensembl
CA378904195 rs1475899705	990	M>I		No	ClinGen gnomAD
rs933784636 CA215762785	990	M>V		No	ClinGen Ensembl
CA5743297 rs760469931	992	Q>R		No	ClinGen ExAC gnomAD
rs1052142234 CA215762786	994	K>Q		No	ClinGen Ensembl
rs1405156269 CA378904906	995	V>A		No	ClinGen gnomAD
rs1367093758 CA378904903	995	V>I		No	ClinGen gnomAD
rs1398707029 CA378904924	998	R>Q		No	ClinGen TOPMed
rs1348391916 CA378904927	999	A>T		No	ClinGen gnomAD
rs1241104323 CA378904934	1000	I>V		No	ClinGen gnomAD
CA5743310 rs773717326	1001	N>K		No	ClinGen ExAC gnomAD
CA378904951 rs1300280923	1002	Q>R		No	ClinGen gnomAD
CA378904970 rs556752202	1005	D>H		No	ClinGen 1000Genomes TOPMed gnomAD
CA215772802 rs556752202	1005	D>Y		No	ClinGen 1000Genomes TOPMed gnomAD
CA378904979 rs1023316151	1006	M>R		No	ClinGen TOPMed gnomAD
CA215772803 rs1023316151	1006	M>T		No	ClinGen TOPMed gnomAD
CA378904977 rs1466606676	1006	M>V		No	ClinGen TOPMed
rs1209277586 CA378904998	1009	K>Q		No	ClinGen gnomAD
rs1289652913 CA378905002	1009	K>R		No	ClinGen gnomAD
rs1223491742 CA378905046	1015	A>V		No	ClinGen gnomAD
CA378905079 rs1471782044	1020	Q>E		No	ClinGen gnomAD
rs747728321 CA5743311	1020	Q>R		No	ClinGen ExAC gnomAD
CA215773374 rs751082778	1024	N>S		No	ClinGen Ensembl
rs750702181 CA5743322	1025	Y>C		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1029	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1338552598 CA378905168	1031	A>T		No	ClinGen gnomAD
CA215773375 rs754620266	1032	F>S		No	ClinGen Ensembl
rs368330561 CA5743325	1034	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA378905193 rs1306029906	1035	Q>E		No	ClinGen gnomAD
CA378905212 rs1229870963	1037	S>F		No	ClinGen gnomAD
rs1344672799 CA378905228	1040	L>V		No	ClinGen gnomAD
CA5743328 rs747602279	1045	S>G		No	ClinGen ExAC gnomAD
CA5743329 rs771596017	1045	S>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1048	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772813516 CA378905285	1048	R>I		No	ClinGen ExAC gnomAD
rs772813516 CA5743330	1048	R>K		No	ClinGen ExAC gnomAD
TCGA novel	1055	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5743351 rs571598696	1056	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs769660658 CA5743353	1058	M>I		No	ClinGen ExAC gnomAD
rs369729371 CA5743352	1058	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1228329689 CA378906507	1059	R>M		No	ClinGen TOPMed gnomAD
rs955714301 CA215774786	1062	I>T		No	ClinGen Ensembl
CA5743354 rs775462971	1063	G>V		No	ClinGen ExAC gnomAD
CA215774787 rs987430227	1067	R>G		No	ClinGen TOPMed
CA5743355 rs762958999	1069	M>L		No	ClinGen ExAC gnomAD
CA5743356 rs768768253	1069	M>T		No	ClinGen ExAC gnomAD
CA378906674 rs1310971854	1071	Y>N		No	ClinGen TOPMed
rs538891858 CA215774788	1073	L>V		No	ClinGen 1000Genomes
CA378907945 rs1356634716	1076	H>D		No	ClinGen gnomAD
CA378907973 rs760626662	1077	K>N		No	ClinGen ExAC gnomAD
rs771076238 CA5743379	1078	I>V		No	ClinGen ExAC gnomAD
rs1052198907 CA215775752	1081	I>V		No	ClinGen TOPMed gnomAD
TCGA novel	1082	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759783494 CA5743381	1085	V>A		No	ClinGen ExAC gnomAD
rs776618144 CA5743380	1085	V>L		No	ClinGen ExAC gnomAD
CA378908080 rs1212431084	1086	G>V		No	ClinGen gnomAD
CA5743383 rs376332631	1087	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA378908105 rs1427462174	1088	I>M		No	ClinGen TOPMed gnomAD
CA378908190 rs1185551682	1095	P>A		No	ClinGen gnomAD
CA215775753 rs547210300	1096	E>K		No	ClinGen 1000Genomes ExAC gnomAD
CA5743388 rs547210300	1096	E>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA215775754 rs371052769	1097	T>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA5743389 rs371052769	1097	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs769248529 CA5743391	1100	R>C		No	ClinGen ExAC TOPMed gnomAD
rs543711382 CA5743392	1100	R>H		No	ClinGen ExAC gnomAD
rs778956657 CA5743394	1102	A>V		No	ClinGen ExAC gnomAD
rs1045658598 CA215775755	1105	P>L		No	ClinGen TOPMed
rs559057300 CA5743396	1106	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	1109	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5743398 rs746002233	1110	M>I		No	ClinGen ExAC gnomAD
CA5743397 rs376214107	1110	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA378908352 rs769937903 CA5743399	1111	M>I		No	ClinGen ExAC gnomAD
CA378908350 rs1483945911	1111	M>T		No	ClinGen TOPMed
CA5743400 rs775710859	1114	E>D		No	ClinGen ExAC gnomAD
CA215775756 rs772802705	1117	S>L		No	ClinGen Ensembl
rs538272737 CA5743403	1119	R>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA378908404 rs538272737	1119	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs762364778 CA5743404	1119	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1446442282 CA378908419	1121	F>S		No	ClinGen gnomAD
CA5743407 rs755695055	1123	M>T		No	ClinGen ExAC gnomAD
CA5743406 rs749876956	1123	M>V		No	ClinGen ExAC gnomAD
rs754665616 CA5743427	1126	N>K		No	ClinGen ExAC
rs764865801 CA5743428	1127	E>D		No	ClinGen ExAC gnomAD
rs1159849946 CA378908479	1127	E>G		No	ClinGen gnomAD
CA5743429 rs372035320	1128	I>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs758143089 CA5743430	1129	I>V		No	ClinGen ExAC gnomAD
CA5743431 rs777724701	1131	K>N		No	ClinGen ExAC TOPMed gnomAD
CA378908521 rs1333959983	1134	H>Y		No	ClinGen gnomAD
CA378908535 rs1241085681	1135	E>D		No	ClinGen gnomAD
CA378908546 rs1354421706	1137	E>G		No	ClinGen gnomAD
rs780093667 CA5743434	1139	G>S		No	ClinGen ExAC TOPMed gnomAD
rs768795514 CA5743436	1143	E>*		No	ClinGen ExAC TOPMed
CA378908585 rs1286713522	1143	E>G		No	ClinGen TOPMed
rs768795514 CA378908584	1143	E>K		No	ClinGen ExAC TOPMed
rs779014762 CA5743437	1144	Q>R		No	ClinGen ExAC gnomAD
rs748493017 CA5743438	1147	V>M		No	ClinGen ExAC gnomAD
TCGA novel	1150	D>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378908633 rs1319470770	1150	D>N		No	ClinGen TOPMed
rs1565037121 CA378908670	1153	L>F		No	ClinGen Ensembl
TCGA novel	1154	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378908682 rs1424098787	1155	E>A		No	ClinGen gnomAD
rs772390566 CA5743461	1156	H>R		No	ClinGen ExAC gnomAD
rs778273756 CA5743462	1157	C>G		No	ClinGen ExAC TOPMed gnomAD
rs373366495 CA5743463	1157	C>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA5743465 rs777293748	1159	K>E		No	ClinGen ExAC gnomAD
CA5743466 rs759069214	1160	H>Y		No	ClinGen ExAC TOPMed gnomAD
rs769154273 CA5743467	1161	K>R		No	ClinGen ExAC TOPMed gnomAD
rs762500269 CA378908735	1162	Y>*		No	ClinGen ExAC gnomAD
rs1295063969 CA378908733	1162	Y>C		No	ClinGen gnomAD
rs751285414 CA5743471	1164	A>T		No	ClinGen ExAC gnomAD
CA5743472 rs761606041	1166	T>I		No	ClinGen ExAC gnomAD
TCGA novel	1167	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1035423763 CA215777189	1168	E>G		No	ClinGen Ensembl
rs750388676 CA5743474	1168	E>K		No	ClinGen ExAC gnomAD
rs1204213099 CA378908782	1170	F>S		No	ClinGen gnomAD
CA215777190 rs758548443	1174	V>F		No	ClinGen ExAC TOPMed gnomAD
CA5743478 rs758548443	1174	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1565037300	1175	V>missing	Variant assessed as Somatic; 4.648e-05 impact. [NCI-TCGA]	No	NCI-TCGA
rs778147174 CA5743479	1176	R>C		No	ClinGen ExAC gnomAD
CA5743480 rs138926927	1176	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5743481 rs138926927	1176	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA378908821 rs1479416720	1177	L>S		No	ClinGen TOPMed gnomAD
CA378908831 rs1178427950	1178	M>T		No	ClinGen gnomAD
CA215777191 rs1026633461	1179	E>D		No	ClinGen gnomAD
CA5743488 rs768132044	1195	N>H		No	ClinGen ExAC gnomAD
rs761553028 CA5743490	1196	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA5743491 rs574978022	1196	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA215777192 rs952439430	1201	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA378909006 rs1486678915	1202	N>S		No	ClinGen gnomAD
rs1216796366 CA378909010	1203	V>M		No	ClinGen gnomAD
rs1457952619 CA378909020	1204	L>P		No	ClinGen TOPMed
CA215777896 rs768874978	1211	E>G		No	ClinGen Ensembl
rs1392282691 CA378909081	1211	E>K		No	ClinGen gnomAD
CA5743504 rs780621285	1213	E>Q		No	ClinGen ExAC gnomAD
rs968604499 CA215777897	1214	E>K		No	ClinGen Ensembl
CA378909110 rs1590794584	1215	M>V		No	ClinGen Ensembl
CA5743505 rs748694096	1217	I>V		No	ClinGen ExAC TOPMed gnomAD
CA378909155 rs1290336805	1219	Y>C		No	ClinGen gnomAD
CA378909170 rs1355201550	1221	Y>C		No	ClinGen gnomAD
rs1350780731 CA378909182	1223	L>F		No	ClinGen TOPMed
rs1306649331 CA378909192	1224	C>S		No	ClinGen TOPMed gnomAD
rs1408753376 CA378909201	1225	D>G		No	ClinGen TOPMed
CA5743519 rs61758437	1231	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA215777998 rs200279056	1236	A>V		No	ClinGen gnomAD
rs1248295074 CA378909315	1241	L>R		No	ClinGen TOPMed
rs1428247782 CA378909317	1242	L>F		No	ClinGen gnomAD
CA378909326 rs1403147569	1243	H>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA5743525 rs778383052	1246	L>F		No	ClinGen ExAC gnomAD
rs370406091 CA5743526	1248	K>E		No	ClinGen ESP ExAC gnomAD
rs1202144671 CA378909358	1248	K>R		No	ClinGen TOPMed
rs1299687177 CA378697163	1249	W>R		No	ClinGen TOPMed
rs1055960911 CA215434374	1250	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA5743553 rs772155501	1252	D>E		No	ClinGen ExAC gnomAD
CA378697264 rs1488794823	1254	C>Y		No	ClinGen TOPMed gnomAD
CA5743554 rs773211951	1255	V>M		No	ClinGen ExAC gnomAD
TCGA novel	1256	A>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1257	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1260	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs766579453 CA5743556	1260	Q>R		No	ClinGen ExAC gnomAD
CA378697355 rs375009537	1261	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs765684085 CA5743559	1261	R>Q	Variant assessed as Somatic; 4.675e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs375009537 CA5743558	1261	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs183890235 CA378697376	1262	D>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5743560 rs753234622	1262	D>G		No	ClinGen ExAC TOPMed gnomAD
rs751096233 CA5743563	1263	G>E		No	ClinGen ExAC gnomAD
CA5743562 rs188270898	1263	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs553671666 CA378697430	1266	A>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA5743564 rs553671666	1266	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA215434471 rs994557124	1268	T>M		No	ClinGen TOPMed gnomAD
rs780721120 CA5743565	1270	G>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1274	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378697565 rs1457579230	1275	Q>H		No	ClinGen gnomAD
rs1200189195 CA378697582	1277	Y>C		No	ClinGen gnomAD
CA5743567 rs756000164	1278	Q>E		No	ClinGen ExAC gnomAD
CA215434498 rs780031433	1278	Q>H		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1279	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1280	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378697645 rs1380553869	1282	H>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1276490876 CA378697664	1283	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1423545706 CA378697657	1283	Y>H		No	ClinGen gnomAD
CA378697693 rs1392611088	1285	D>N		No	ClinGen TOPMed gnomAD
rs1405941293 CA378697734	1288	K>E		No	ClinGen gnomAD
CA5743615 rs749625059	1289	M>L		No	ClinGen ExAC gnomAD
CA378701089 rs1590910412	1291	E>D		No	ClinGen Ensembl
CA5743616 rs768871901	1291	E>V		No	ClinGen ExAC gnomAD
rs903019098 CA215445127	1293	A>S		No	ClinGen TOPMed
TCGA novel	1295	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772769660 CA5743619	1296	L>F		No	ClinGen ExAC TOPMed gnomAD
CA5743618 rs762210154	1296	L>W		No	ClinGen ExAC TOPMed gnomAD
CA378701249 rs1300667749	1298	K>R		No	ClinGen gnomAD
CA5743621 rs760276699	1301	A>T		No	ClinGen ExAC gnomAD
rs1378722148 CA378701339	1301	A>V		No	ClinGen gnomAD
rs759277250 CA5743625	1302	E>D		No	ClinGen ExAC TOPMed gnomAD
rs753464561 CA5743623	1302	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	1304	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1456888349 CA378701399	1304	Y>N		No	ClinGen gnomAD
CA378701479 rs1295776732	1306	N>S		No	ClinGen gnomAD
CA5743627 rs61758438	1307	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA5743628 rs777699040	1308	M>I		No	ClinGen ExAC gnomAD
rs1378665575 CA378701541	1308	M>T		No	ClinGen gnomAD
CA215445152 rs926045680	1308	M>V		No	ClinGen TOPMed gnomAD
rs1377766992 CA378701605	1310	D>A		No	ClinGen TOPMed
rs1377766992 CA378701613	1310	D>G		No	ClinGen TOPMed
CA5743630 rs756213333	1313	Q>K		No	ClinGen ExAC gnomAD
CA5743631 rs780218829	1313	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA5743633 rs768979955	1315	S>G		No	ClinGen ExAC gnomAD
rs1198103347 CA378701748	1315	S>N		No	ClinGen gnomAD
rs557378130 CA5743634	1316	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1179477977 CA378701817	1317	L>F		No	ClinGen gnomAD
CA5743649 rs771320376	1319	K>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1320	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378702364 rs754014975	1321	Q>E		No	ClinGen ExAC TOPMed gnomAD
CA5743650 rs754014975	1321	Q>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1321	Q>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1303281071 CA378702443	1326	E>*		No	ClinGen gnomAD
rs969991889 CA215445734	1327	N>K		No	ClinGen Ensembl
CA5743653 rs748476214	1329	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1279978319 CA378702530	1330	K>R		No	ClinGen gnomAD
rs1227205955 CA378702545	1332	I>F		No	ClinGen TOPMed
CA5743657 rs771529880	1334	P>A		No	ClinGen ExAC gnomAD
TCGA novel	1334	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745390687 CA5743659	1335	K>N		No	ClinGen ExAC TOPMed gnomAD
CA5743660 rs769279030	1336	P>L		No	ClinGen ExAC gnomAD
CA378702642 rs769279030	1336	P>R		No	ClinGen ExAC gnomAD
CA5743661 rs775236644	1337	D>G		No	ClinGen ExAC gnomAD
CA378702650 rs1488151491	1337	D>H		No	ClinGen gnomAD
CA5743663 rs763850565	1338	Y>C		No	ClinGen ExAC gnomAD
CA378702694 rs1172013849	1339	F>L		No	ClinGen gnomAD
rs1403163031 CA378702703	1341	V>I		No	ClinGen gnomAD
rs1171489658 CA378702742	1344	Y>C		No	ClinGen gnomAD
rs767493420 CA5743666	1345	G>R		No	ClinGen ExAC gnomAD
CA378702780 rs1176302935	1347	G>A		No	ClinGen TOPMed gnomAD
rs1176302935 CA378702778	1347	G>E		No	ClinGen TOPMed gnomAD
CA378702784 rs1590916250	1348	F>V		No	ClinGen Ensembl
CA215445776 rs774670516	1349	P>L		No	ClinGen Ensembl
TCGA novel	1351	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs755108989 CA5743668	1353	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1293651177 CA378702836	1353	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1472361796 CA378703094	1354	G>E		No	ClinGen TOPMed gnomAD
TCGA novel	1354	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200738890 CA5743690	1356	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA5743691 rs570650112	1359	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA378703126 rs1326738890	1359	Y>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs751916779 CA5743692	1360	R>*		No	ClinGen ExAC gnomAD
CA378703134 rs1333578550	1360	R>Q		No	ClinGen gnomAD
CA378703146 rs1489882175	1362	K>R		No	ClinGen TOPMed
TCGA novel	1363	E>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378703176 rs1234426888	1366	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA378703177 rs1256927561	1366	R>H		No	ClinGen TOPMed gnomAD
CA5743695 rs750915688	1367	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs781447632 CA5743694	1367	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1250824243 CA378703201	1370	F>L		No	ClinGen gnomAD
CA5743696 rs756633592	1372	A>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA5743697 rs779535490	1372	A>V		No	ClinGen ExAC gnomAD
CA378703221 rs1473117477	1373	R>Q		No	ClinGen TOPMed gnomAD
TCGA novel	1373	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215447446 rs539143909	1378	F>S		No	ClinGen 1000Genomes
CA378703265 rs1169845204	1380	N>D		No	ClinGen gnomAD
rs778556643 CA378703272	1381	A>S		No	ClinGen ExAC TOPMed gnomAD
CA5743700 rs778556643	1381	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5743702 rs771871044	1382	E>K		No	ClinGen ExAC TOPMed gnomAD
CA215447453 rs940501936	1383	K>E		No	ClinGen TOPMed
CA378703316 rs1395598829	1387	T>P		No	ClinGen gnomAD
rs760648165 CA5743704	1391	G>A		No	ClinGen ExAC gnomAD
rs760648165 CA378703342	1391	G>V		No	ClinGen ExAC gnomAD
CA5743707 rs763142156	1392	D>N		No	ClinGen ExAC TOPMed gnomAD
rs543463732 CA378703351	1393	D>H		No	ClinGen ExAC TOPMed gnomAD
CA5743709 rs543463732	1393	D>N		No	ClinGen ExAC TOPMed gnomAD
CA5743710 rs761987434	1394	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs113965990 CA5743711	1396	N>T		No	ClinGen ExAC TOPMed gnomAD
rs1485858176 CA378703433	1398	P>S		No	ClinGen gnomAD
rs759675258 CA378703471	1400	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA5743727 rs768831824	1401	Y>C		No	ClinGen ExAC gnomAD
CA5743726 rs768831824	1401	Y>F		No	ClinGen ExAC gnomAD
CA5743728 rs762086660	1403	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA378703648 rs1181795810	1409	P>S		No	ClinGen gnomAD
rs773566920 CA5743730	1412	D>N		No	ClinGen ExAC gnomAD
TCGA novel	1414	P>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378703734 rs1014668292	1415	P>A		No	ClinGen TOPMed gnomAD
rs1359007352 CA378703737	1415	P>L		No	ClinGen gnomAD
rs1014668292 CA215447516	1415	P>S		No	ClinGen TOPMed gnomAD
CA378703731 rs1014668292	1415	P>T		No	ClinGen TOPMed gnomAD
CA378703784 rs754314509	1419	R>K		No	ClinGen ExAC TOPMed gnomAD
rs754314509 CA5743733	1419	R>T		No	ClinGen ExAC TOPMed gnomAD
rs1385068190 CA378703802	1421	V>M		No	ClinGen Ensembl
rs755529954 CA5743734	1422	S>P		No	ClinGen ExAC gnomAD
CA378703832 rs1384588200	1423	E>A		No	ClinGen gnomAD
CA5743735 rs764713332	1424	Q>E		No	ClinGen ExAC gnomAD
rs779179594 CA215447517	1424	Q>H		No	ClinGen Ensembl
CA378703840 rs764713332	1424	Q>K		No	ClinGen ExAC gnomAD
rs752217390 CA5743736	1426	V>I		No	ClinGen ExAC gnomAD
CA378703885 rs1238966148	1427	S>C		No	ClinGen gnomAD
TCGA novel	1428	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1431	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1433	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777958830 CA5743764	1433	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5743765 rs747221336	1434	V>F		No	ClinGen ExAC gnomAD
CA5743766 rs747221336	1434	V>I		No	ClinGen ExAC gnomAD
TCGA novel	1436	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs932923212 CA378704132	1436	R>G		No	ClinGen TOPMed
rs1050075199 CA215448062	1436	R>Q		No	ClinGen gnomAD
CA378704139 rs1199952429	1437	F>Y		No	ClinGen TOPMed
rs756231427 CA215448063	1439	Y>*		No	ClinGen Ensembl
rs776914792 CA5743767	1441	R>Q		No	ClinGen ExAC gnomAD
TCGA novel	1441	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5743769 rs367916159	1443	I>T		No	ClinGen ESP ExAC gnomAD
rs759911543 CA5743768	1443	I>V		No	ClinGen ExAC TOPMed gnomAD
rs527767220 CA5743771	1444	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1590941742 CA378704201	1447	E>A		No	ClinGen Ensembl
TCGA novel	1448	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1376673571 CA378704217	1449	N>T		No	ClinGen gnomAD
rs370398125 CA5743772	1450	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA5743774 rs761487030	1451	D>E		No	ClinGen ExAC gnomAD
CA5743773 rs751178935	1451	D>G		No	ClinGen ExAC gnomAD
CA215448087 rs777850348	1453	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA5743775 rs200693040	1455	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5743802 rs772966246	1456	N>T		No	ClinGen ExAC gnomAD
rs760423213 CA5743803	1459	I>M		No	ClinGen ExAC TOPMed gnomAD
rs369679951 CA5743805	1460	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1463	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5743807 rs765174319	1463	I>T		No	ClinGen ExAC gnomAD
TCGA novel	1463	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215454612 rs926802049	1465	T>A		No	ClinGen TOPMed gnomAD
CA5743809 rs757362875	1465	T>I		No	ClinGen ExAC TOPMed gnomAD
CA378704577 rs757362875	1465	T>K		No	ClinGen ExAC TOPMed gnomAD
rs746070886 CA5743811	1466	T>A		No	ClinGen ExAC gnomAD
rs766952825 CA215454634	1466	T>I		No	ClinGen Ensembl
CA215454639 rs766952825	1466	T>N		No	ClinGen Ensembl
TCGA novel	1477	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5743814 rs780214260	1480	K>N		No	ClinGen ExAC gnomAD
CA5743815 rs749672814	1481	S>F		No	ClinGen ExAC gnomAD
rs914199655 CA215454656	1482	V>F		No	ClinGen TOPMed gnomAD
TCGA novel	1482	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs370127033	1485	V>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs368027943 CA5743842	1485	V>M		No	ClinGen ESP ExAC gnomAD
rs571507465 CA5743844	1486	E>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	1486	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1419055388 CA378705047	1488	S>N		No	ClinGen TOPMed
rs762807328 CA5743846	1492	N>K		No	ClinGen ExAC TOPMed gnomAD
rs2229600 CA215456491	1494	I>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA215456481 rs1013682202	1494	I>T		No	ClinGen TOPMed gnomAD
rs760837044 CA215456497	1495	E>*		No	ClinGen ExAC gnomAD
CA5743849 rs760837044	1495	E>K		No	ClinGen ExAC gnomAD
CA378705100 rs1213319025	1496	T>I		No	ClinGen TOPMed
CA5743850 rs766407265	1498	Q>E		No	ClinGen ExAC gnomAD
CA5743852 rs557337834	1500	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA378705128 rs1197163041	1501	N>D		No	ClinGen gnomAD
CA5743854 rs753116576	1501	N>S		No	ClinGen ExAC TOPMed gnomAD
CA5743856 rs369052092	1502	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA378705178 rs1404175202	1507	M>I		No	ClinGen Ensembl
TCGA novel	1507	M>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378705172 rs1259544454	1507	M>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA378705181 rs1328859274	1508	V>M		No	ClinGen TOPMed
CA215456546 rs777096693	1511	H>Q		No	ClinGen Ensembl
CA378705232 rs1188826384	1515	P>T		No	ClinGen gnomAD
rs377456428 CA5743858	1516	S>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1460702393 CA378705239	1516	S>N		No	ClinGen TOPMed gnomAD
CA5743859 rs780618907	1517	L>R		No	ClinGen ExAC gnomAD
rs1399534546 CA378705253	1518	P>L		No	ClinGen gnomAD
CA378705255 rs1328402150	1519	I>V		No	ClinGen TOPMed
CA5743861 rs769437313	1520	N>S	Variant assessed as Somatic; 4.627e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs369947359 CA215456574	1521	P>L		No	ClinGen ESP TOPMed
rs774313094 CA5743865	1524	M>V		No	ClinGen ExAC gnomAD
TCGA novel	1525	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs185222787 CA5743868	1527	N>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1533	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378705361 rs1485989232	1535	M>T		No	ClinGen TOPMed gnomAD
CA5743872 rs758865912	1538	F>L		No	ClinGen ExAC
rs370120157 CA5743874	1539	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1345590772 CA378705401	1541	Y>C		No	ClinGen TOPMed
rs1373864109 CA378705405	1542	E>K	Variant assessed as Somatic; 4.718e-05 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA5743876 rs780752467	1543	K>E		No	ClinGen ExAC gnomAD
rs749893339 CA5743898	1544	A>V		No	ClinGen ExAC gnomAD
TCGA novel	1545	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1033275695 CA215457421	1547	T>I		No	ClinGen gnomAD
CA378705455 rs1033275695	1547	T>R		No	ClinGen gnomAD
rs779586829 CA5743900	1547	T>S		No	ClinGen ExAC gnomAD
rs1445787407 CA378705457	1548	D>N		No	ClinGen gnomAD
CA378705464 rs748922919	1549	R>G		No	ClinGen ExAC TOPMed gnomAD
CA5743902 rs754653090	1549	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs748922919 CA5743901	1549	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1239652909 CA378705473	1550	Y>*		No	ClinGen gnomAD
rs775545896 CA215457428	1550	Y>F		No	ClinGen Ensembl
rs1261428829 CA378705477	1551	L>P		No	ClinGen gnomAD
CA5743904 rs41282902	1553	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA378705495 rs1255143724	1554	H>D		No	ClinGen gnomAD
rs771997714 CA5743905	1555	P>S		No	ClinGen ExAC gnomAD
rs976087948 CA215457450	1557	A>S		No	ClinGen gnomAD
rs1421443887 CA378705524	1558	H>R		No	ClinGen gnomAD
rs1417724348 CA378705532	1559	E>G		No	ClinGen gnomAD
rs1459433632 CA378705543	1560	K>N		No	ClinGen gnomAD
CA215457460 rs377395109	1561	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA378705547 rs1268682204	1561	I>N		No	ClinGen TOPMed
CA5743909 rs775773512	1562	E>K		No	ClinGen ExAC TOPMed gnomAD
CA5743910 rs370441071	1565	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs375937964 CA215457482	1565	K>R		No	ClinGen ESP gnomAD
rs1311957284 CA378705580	1566	D>G		No	ClinGen gnomAD
rs774725509 CA5743912	1566	D>N		No	ClinGen ExAC TOPMed gnomAD
CA378705588 rs1165198053	1567	L>Q		No	ClinGen TOPMed
rs1353427528 CA378705591	1568	I>F		No	ClinGen gnomAD
CA378705595 rs1282872622	1568	I>M		No	ClinGen TOPMed gnomAD
CA378705593 rs1231536960	1568	I>T		No	ClinGen TOPMed gnomAD
rs1275124433 CA378705599	1569	A>G		No	ClinGen TOPMed gnomAD
rs912863246 CA215457483	1569	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA378705600 rs1275124433	1569	A>V		No	ClinGen TOPMed gnomAD
rs1335797705 CA378705607	1570	W>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	1570	W>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs375042364 CA5743926	1573	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs771062074 CA5743927	1574	F>L		No	ClinGen ExAC TOPMed gnomAD
CA378705661 rs1436543387	1576	A>V		No	ClinGen gnomAD
CA5743929 rs368905884	1577	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA5743930 rs371341893	1579	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1364431386 CA378705705	1583	G>*		No	ClinGen gnomAD
CA378705707 rs1229385466	1583	G>A		No	ClinGen gnomAD
CA378705709 rs1346206524	1584	D>N		No	ClinGen gnomAD
TCGA novel	1585	K>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378705718 rs1236890691	1585	K>E		No	ClinGen gnomAD
CA378705735 rs1386524728	1587	T>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA378705741 rs1361816231	1588	E>G		No	ClinGen TOPMed
CA5743933 rs772411152	1589	A>V		No	ClinGen ExAC gnomAD
TCGA novel	1590	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378705755 rs1243334883	1591	R>G		No	ClinGen gnomAD
CA5743934 rs773632498	1592	P>L		No	ClinGen ExAC gnomAD
CA5743935 rs773632498	1592	P>R		No	ClinGen ExAC gnomAD
rs377304209 CA5743938	1595	E>K		No	ClinGen ESP ExAC gnomAD
CA215461572 rs549869641	1596	R>S		No	ClinGen 1000Genomes
rs1173969057 CA378705801	1597	M>I		No	ClinGen gnomAD
CA5743939 rs192122020	1598	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs752272582 CA5743940	1599	A>T		No	ClinGen ExAC gnomAD
rs1157084165 CA378705813	1599	A>V		No	ClinGen TOPMed gnomAD
rs777709012 CA5743942	1602	K>R		No	ClinGen ExAC gnomAD
rs1212201667 CA378705842	1603	Q>L		No	ClinGen TOPMed
CA378705874 rs1368979040	1607	K>N		No	ClinGen gnomAD
CA378705895 rs1486966000	1610	K>R		No	ClinGen TOPMed
TCGA novel	1612	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745854253 CA5743946	1613	G>S		No	ClinGen ExAC TOPMed gnomAD
CA5743948 rs779105233	1614	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1354875886 CA378705925	1615	R>*		No	ClinGen TOPMed
rs748312033 CA5743949	1615	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs773506065 CA5743951	1617	M>L		No	ClinGen ExAC gnomAD
CA5743975 rs774808081	1620	S>G		No	ClinGen ExAC TOPMed gnomAD
CA378705970 rs1290955727	1620	S>T		No	ClinGen gnomAD
rs559196315 CA215468469	1622	D>E		No	ClinGen Ensembl
rs1451999504 CA378705982	1622	D>G		No	ClinGen TOPMed
rs762578228 CA5743976	1622	D>H		No	ClinGen ExAC gnomAD
CA378705989 rs1244819995	1623	D>G		No	ClinGen gnomAD
rs1565088975 CA378705985	1623	D>N		No	ClinGen Ensembl
rs1244819995 CA378705990	1623	D>V		No	ClinGen gnomAD
CA378706023 rs1336971745	1628	R>C		No	ClinGen gnomAD
rs774121100 CA5743978	1628	R>H		No	ClinGen ExAC TOPMed gnomAD
CA378706024 rs774121100	1628	R>P		No	ClinGen ExAC TOPMed gnomAD
rs1485334624 CA378706031	1629	P>L		No	ClinGen gnomAD
CA5743983 rs755946295	1630	R>P		No	ClinGen ExAC TOPMed gnomAD
CA5743982 rs755946295	1630	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs750234584 CA5743981	1630	R>W		No	ClinGen ExAC TOPMed gnomAD
CA378706034 rs1591041266	1631	S>A		No	ClinGen Ensembl
CA378706044 rs1444218092	1632	M>T		No	ClinGen gnomAD
CA378706041 rs1565089031	1632	M>V		No	ClinGen Ensembl
CA378706052 rs1591041338	1633	V>G		No	ClinGen Ensembl
CA5743984 rs542877171	1633	V>L		No	ClinGen 1000Genomes ExAC gnomAD
rs542877171 CA5743985	1633	V>M		No	ClinGen 1000Genomes ExAC gnomAD
rs374682976 CA5743987	1634	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs777880965 CA5743986	1634	R>W		No	ClinGen ExAC TOPMed gnomAD
rs757545054 CA5743988	1637	T>M		No	ClinGen ExAC TOPMed gnomAD
CA5743990 rs746260898	1641	S>A		No	ClinGen ExAC TOPMed gnomAD
rs886478094 CA215468545	1641	S>L		No	ClinGen Ensembl
rs571051175 CA215468547	1643	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs776099873 CA5743992	1643	R>H		No	ClinGen ExAC TOPMed gnomAD
CA215468587 rs561000918	1651	S>F		No	ClinGen 1000Genomes TOPMed
rs368031419 CA5743998	1655	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA378706185 rs753753747	1656	D>E		No	ClinGen ExAC TOPMed gnomAD
CA5744000 rs766127221	1656	D>H		No	ClinGen ExAC gnomAD
CA5744002 rs754968178	1657	S>N		No	ClinGen ExAC gnomAD
CA378706196 rs1379145417	1658	T>N		No	ClinGen TOPMed
rs764157392 CA5744003	1660	S>P		No	ClinGen ExAC gnomAD
CA378706210 rs1190718970	1661	R>G		No	ClinGen gnomAD
CA378706214 rs1248828022	1661	R>I		No	ClinGen gnomAD
rs1248828022 CA378706212	1661	R>K		No	ClinGen gnomAD
rs756475538	1665	D>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs750717801 CA5744007	1665	D>N		No	ClinGen ExAC TOPMed gnomAD
CA378706244 rs1206625898	1666	G>W		No	ClinGen TOPMed
CA215473221 rs886680655	1668	A>P		No	ClinGen TOPMed gnomAD
rs1337389584 CA378706597	1668	A>V		No	ClinGen gnomAD
CA378706603 rs1591064187	1669	L>R		No	ClinGen Ensembl
rs1230384056 CA378706606	1670	E>*		No	ClinGen gnomAD
CA378706614 rs1466809357	1671	P>S		No	ClinGen gnomAD
CA215473223 rs575108104	1674	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA378706629 rs575108104	1674	P>T		No	ClinGen gnomAD
CA5744022 rs765215139	1678	H>D		No	ClinGen ExAC gnomAD
CA378706661 rs1179223260	1678	H>P		No	ClinGen gnomAD
CA378706660 rs765215139	1678	H>Y		No	ClinGen ExAC gnomAD
rs555318752 CA215473241	1679	S>A		No	ClinGen Ensembl
CA378706677 rs372787583	1680	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1212278173 CA378706674	1680	R>T		No	ClinGen TOPMed
CA378706706 rs1013901279	1684	K>N		No	ClinGen TOPMed gnomAD
CA5744024 rs375994214	1684	K>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1317775622 CA378706708	1685	L>V		No	ClinGen TOPMed
rs1182341810 CA378706716	1686	D>G		No	ClinGen gnomAD
CA378706743 rs1416493583	1689	D>E		No	ClinGen TOPMed gnomAD
TCGA novel	1689	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378706774 rs1474043534	1694	K>E		No	ClinGen gnomAD
CA215473282 rs78422369	1696	D>E		No	ClinGen Ensembl
rs1051019 CA378706821	1700	E>*		No	ClinGen gnomAD
rs1372395240 CA378706824	1700	E>G		No	ClinGen TOPMed gnomAD
rs1051019 CA215473309	1700	E>K		No	ClinGen gnomAD
CA378706828 rs1410338574	1701	K>E		No	ClinGen gnomAD
TCGA novel	1702	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378706839 rs1308759525	1702	R>K		No	ClinGen gnomAD
CA5744028 rs780565089	1704	S>I		No	ClinGen ExAC gnomAD
CA378706879 rs1315130051	1707	Q>H		No	ClinGen gnomAD
CA5744031 rs779605428	1709	I>T		No	ClinGen ExAC gnomAD
rs755521993 CA5744030	1709	I>V		No	ClinGen ExAC gnomAD
CA378706901 rs748484734	1710	F>L		No	ClinGen TOPMed gnomAD
rs748634880 CA5744032	1712	K>E		No	ClinGen ExAC gnomAD
CA5744033 rs540102365	1713	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1591064679 CA378706938	1715	K>N		No	ClinGen Ensembl
rs772398292 CA5744034	1716	P>S		No	ClinGen ExAC TOPMed gnomAD
CA5744035 rs551703160	1717	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	1717	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378706950 rs1183031479	1718	D>N		No	ClinGen TOPMed gnomAD
rs770554319 CA5744036	1719	I>V		No	ClinGen ExAC gnomAD
rs867511436 CA215473358	1720	S>F		No	ClinGen gnomAD
rs867511436 CA378706967	1720	S>Y		No	ClinGen gnomAD
rs1189253467 CA378706973	1721	L>P		No	ClinGen TOPMed
CA215473369 rs911868740	1722	Q>H		No	ClinGen Ensembl
CA215473364 rs781248318	1722	Q>L		No	ClinGen Ensembl
CA378707006 rs1168119339	1726	A>G		No	ClinGen gnomAD
CA215473372 rs377511922	1726	A>T		No	ClinGen ESP TOPMed
CA215473374 rs79347044	1727	V>G		No	ClinGen Ensembl
TCGA novel	1729	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5744037 rs369249792	1730	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs899262328 CA215473409	1731	E>K		No	ClinGen Ensembl
CA5744039 rs34175019	1732	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1279908459 CA378707055	1733	I>L		No	ClinGen gnomAD
CA378707054 rs1279908459	1733	I>V		No	ClinGen gnomAD
rs1212969271 CA378707073	1735	P>L		No	ClinGen gnomAD
CA378707070 rs1315839127	1735	P>S		No	ClinGen gnomAD
CA378707080 rs1465060783	1737	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA5744059 rs768536912	1737	R>W	Variant assessed as Somatic; 5.558e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs920786835 CA215477688	1739	Q>H		No	ClinGen Ensembl
CA5744060 rs201179287	1741	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201179287 CA378707107	1741	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1741	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA378707112 rs1478989404	1742	K>R		No	ClinGen gnomAD
rs1191730858 CA378707119	1743	S>N		No	ClinGen gnomAD
CA378707144 CA378707145 rs1407095341	1746	M>I		No	ClinGen gnomAD
rs1458588876 CA378707151	1747	N>S		No	ClinGen TOPMed
rs201973019 CA5744064	1748	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1391185202 CA378707164	1749	I>T		No	ClinGen gnomAD
rs1457947484 CA378707174	1750	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs765629500 CA5744065	1751	S>G		No	ClinGen ExAC gnomAD
CA5744067 rs143736792	1751	S>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1315396631 CA378707198	1752	E>D		No	ClinGen TOPMed
rs368735026 CA5744068	1752	E>K		No	ClinGen ESP ExAC gnomAD
CA5744069 rs751046805	1754	R>C		No	ClinGen ExAC TOPMed gnomAD
CA5744070 rs756712008	1754	R>H		No	ClinGen ExAC gnomAD
rs756712008 CA5744071	1754	R>L		No	ClinGen ExAC gnomAD
TCGA novel	1755	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs41314432 CA5744072	1756	S>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs774014626 CA5744074	1757	V>L		No	ClinGen ExAC TOPMed gnomAD
CA215477803 rs950666492	1758	S>F		No	ClinGen TOPMed gnomAD
CA378707258 rs1453133145	1759	P>S		No	ClinGen gnomAD
rs566240366 CA5744076	1760	S>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	1760	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs566240366 CA378707269	1760	S>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs748120235 CA5744078	1761	S>L		No	ClinGen ExAC TOPMed gnomAD
CA5744079 rs771076657	1762	P>L		No	ClinGen ExAC TOPMed gnomAD
CA215477832 rs956007958	1762	P>S		No	ClinGen Ensembl
rs373740290 CA5744081	1765	Q>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5744082 rs765612707	1768	P>H		No	ClinGen ExAC gnomAD
TCGA novel	1768	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5744085 rs764547171	1769	P>L		No	ClinGen ExAC gnomAD
CA5744084 rs763264898	1769	P>T		No	ClinGen ExAC TOPMed gnomAD
rs751958118 CA5744086	1770	P>A		No	ClinGen ExAC gnomAD
rs1350607994 CA378707377	1772	T>I		No	ClinGen TOPMed gnomAD
rs1232102829 CA378707384	1773	P>L		No	ClinGen gnomAD
rs767014234 CA5744088	1776	K>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1777	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215477877 rs975243988	1778	S>G		No	ClinGen Ensembl
rs749997656 CA5744089	1778	S>N		No	ClinGen ExAC gnomAD
rs755744605 CA5744090	1778	S>R		No	ClinGen ExAC TOPMed gnomAD
rs779615103 CA5744091	1779	F>I		No	ClinGen ExAC gnomAD
rs372329635 CA215477890	1781	M>L		No	ClinGen TOPMed
CA5744092 rs377449039	1782	Q>H		No	ClinGen ESP ExAC gnomAD
rs1483429564 CA378707503	1783	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	1783	S>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5744094 rs778782461	1784	S>C		No	ClinGen ExAC gnomAD
rs1230942034 CA378706262	1784	S>I		No	ClinGen gnomAD
TCGA novel	1786	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774680101 CA5744122	1786	E>Q		No	ClinGen ExAC gnomAD
CA5744123 rs748554704	1786	E>V		No	ClinGen ExAC gnomAD
rs377311503 CA5744125	1789	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs368255250 CA5744126	1789	G>V		No	ClinGen ESP ExAC gnomAD
rs765740645 CA5744127	1791	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA378706312 rs1197399326	1792	G>E		No	ClinGen TOPMed gnomAD
CA5744129 VAR_059971 rs869801	1793	A>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs375977899 CA5744130	1793	A>V	Variant assessed as Somatic; 0.0001402 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs764000818 CA5744133	1795	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1256993806 CA378706332	1796	A>T		No	ClinGen TOPMed gnomAD
CA378706344 CA378706343 rs1384819860	1797	D>E		No	ClinGen TOPMed gnomAD
rs757219377 CA5744135	1797	D>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1798	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1303338144 CA378706356	1799	P>L		No	ClinGen gnomAD
rs779989177 CA5744136	1801	P>A		No	ClinGen ExAC gnomAD
TCGA novel	1801	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215449857 rs770399255	1801	P>R		No	ClinGen Ensembl
TCGA novel	1801	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1234141477 CA378706375	1803	P>H		No	ClinGen gnomAD
TCGA novel	1803	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1803	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749438796 CA5744137	1804	L>F		No	ClinGen ExAC gnomAD
rs1327403817 CA378706387	1805	K>R		No	ClinGen gnomAD
CA378706400 rs1210855739	1807	S>N		No	ClinGen gnomAD
CA378706404 rs755126443	1807	S>R		No	ClinGen ExAC TOPMed gnomAD
rs779069875 CA378706405	1808	V>L		No	ClinGen ExAC TOPMed gnomAD
rs779069875 CA5744139	1808	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5744140 rs748393302	1809	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA5744141 rs535574050	1810	D>E		No	ClinGen 1000Genomes ExAC gnomAD
rs773571301 CA5744142	1811	Y>D		No	ClinGen ExAC gnomAD
rs201376871 CA5744143	1812	G>R		No	ClinGen ExAC TOPMed gnomAD
CA5744144 rs771525670	1816	E>K		No	ClinGen ExAC TOPMed gnomAD
CA5744145 rs775981682	1819	D>A		No	ClinGen ExAC gnomAD
CA5744146 rs759123439	1820	L>F		No	ClinGen ExAC gnomAD
CA378706497 rs1445764860	1821	L>P		No	ClinGen gnomAD
CA378706500 rs1391437088	1822	G>C		No	ClinGen gnomAD
CA215449906 rs750265827	1823	S>L		No	ClinGen TOPMed gnomAD
CA5744148 rs775231422	1824	P>R		No	ClinGen ExAC gnomAD
rs1230242015 CA378706512	1824	P>S		No	ClinGen gnomAD
CA5744149 rs762705029	1825	T>A		No	ClinGen ExAC gnomAD
rs1591101195 CA378706525	1826	P>L		No	ClinGen Ensembl
rs1395832222 CA378706531	1827	P>L		No	ClinGen TOPMed
rs757123723 CA5744152	1828	P>L		No	ClinGen ExAC TOPMed gnomAD
CA378706533 rs751435075	1828	P>S		No	ClinGen ExAC TOPMed gnomAD
rs751435075 CA5744151	1828	P>T		No	ClinGen ExAC TOPMed gnomAD
CA215449936 rs1051040175	1829	P>L		No	ClinGen gnomAD
CA215449952 rs889763172	1830	P>L		No	ClinGen TOPMed gnomAD
rs1483759886 CA378706549	1831	P>L		No	ClinGen gnomAD
rs1179191359 CA378706562	1833	Q>*		No	ClinGen TOPMed
rs1179191359 CA378706561	1833	Q>E		No	ClinGen TOPMed
CA378706566 rs1375745164	1833	Q>H		No	ClinGen gnomAD
CA5744157 rs778979577	1834	R>G		No	ClinGen ExAC gnomAD
CA378706570 rs1166717804	1834	R>T		No	ClinGen gnomAD
CA5744177 rs773681145	1840	L>P		No	ClinGen ExAC gnomAD
TCGA novel	1841	P>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1490298263 CA378707273	1841	P>T		No	ClinGen TOPMed
rs1295844014 CA378707294	1842	S>N		No	ClinGen gnomAD
rs1409926515 CA378707323	1843	K>N		No	ClinGen gnomAD
CA378707320 rs1368035771	1843	K>R		No	ClinGen gnomAD
rs765297075 CA5744178	1845	P>L		No	ClinGen ExAC gnomAD
TCGA novel	1845	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs868636153 CA215451429	1847	P>L		No	ClinGen Ensembl
TCGA novel	1847	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs778097474 CA5744181	1849	P>A		No	ClinGen ExAC TOPMed gnomAD
CA378707413 rs1295023705	1849	P>L		No	ClinGen TOPMed
TCGA novel	1849	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA215451432 rs778097474	1849	P>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1851	K>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751759224 CA5744182	1852	T>A		No	ClinGen ExAC gnomAD
rs781421126 CA5744184	1854	R>C		No	ClinGen ExAC gnomAD
CA5744186 rs373416529	1854	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5744185 rs373416529	1854	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA378707517 rs2229603	1857	A>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA378707515 rs2229603	1857	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5744188 rs2229603	1857	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5744189 rs369390395	1858	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA378707527 rs369390395	1858	S>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA378707534 rs1407193831	1860	D>N		No	ClinGen gnomAD
rs199537179 CA215451458	1862	G>R		No	ClinGen TOPMed gnomAD
CA5744193 rs377121875	1863	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA378707557 rs1391327078	1863	I>T		No	ClinGen gnomAD
CA5744194 rs370457490	1864	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA5744195 rs370457490	1864	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA5744196 rs752741957	1865	Q>*		No	ClinGen ExAC
rs1366107215 CA378707566	1865	Q>R		No	ClinGen gnomAD
TCGA novel	1866	Q>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA

No associated diseases with Q14185

9 regional properties for Q14185

Type	Name	Position	InterPro Accession
domain	SH3 domain	9 - 70	IPR001452
domain	C2 DOCK-type domain	421 - 617	IPR027007
domain	DOCKER domain	1207 - 1617	IPR027357
domain	Dedicator of cytokinesis, N-terminal domain	73 - 416	IPR032376
domain	DOCKER, Lobe A	1202 - 1330	IPR046769
domain	DOCKER, Lobe B	1388 - 1469	IPR046770
domain	DOCKER, Lobe C	1508 - 1610	IPR046773
domain	Dedicator of cytokinesis protein 1/5, SH3 domain	13 - 68	IPR047025
domain	Dedicator of cytokinesis protein 1, C2 domain	424 - 619	IPR047026

Functions

		Description
EC Number
Subcellular Localization	Cytoplasm Membrane	Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

6 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
guanyl-nucleotide exchange factor complex	A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.
nuclear speck	A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name	Definition
GTPase activator activity	Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
guanyl-nucleotide exchange factor activity	Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.
SH3 domain binding	Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
small GTPase binding	Binding to a small monomeric GTPase.

9 GO annotations of biological process

Name	Definition
apoptotic process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
cell migration	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
integrin-mediated signaling pathway	The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
myoblast fusion	A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
phagocytosis, engulfment	The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
positive regulation of epithelial cell migration	Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
positive regulation of substrate adhesion-dependent cell spreading	Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
signal transduction	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
small GTPase mediated signal transduction	The series of molecular signals in which a small monomeric GTPase relays a signal.

5 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9H7D0	DOCK5	Dedicator of cytokinesis protein 5	Homo sapiens (Human)	PR
Q92608	DOCK2	Dedicator of cytokinesis protein 2	Homo sapiens (Human)	PR
Q8CIQ7	Dock3	Dedicator of cytokinesis protein 3	Mus musculus (Mouse)	PR
Q8C3J5	Dock2	Dedicator of cytokinesis protein 2	Mus musculus (Mouse)	PR
Q8BUR4	Dock1	Dedicator of cytokinesis protein 1	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MTRWVPTKRE	EKYGVAFYNY	DARGADELSL	QIGDTVHILE	TYEGWYRGYT	LRKKSKKGIF
70	80	90	100	110	120
PASYIHLKEA	IVEGKGQHET	VIPGDLPLIQ	EVTTTLREWS	TIWRQLYVQD	NREMFRSVRH
130	140	150	160	170	180
MIYDLIEWRS	QILSGTLPQD	ELKELKKKVT	AKIDYGNRIL	DLDLVVRDED	GNILDPELTS
190	200	210	220	230	240
TISLFRAHEI	ASKQVEERLQ	EEKSQKQNID	INRQAKFAAT	PSLALFVNLK	NVVCKIGEDA
250	260	270	280	290	300
EVLMSLYDPV	ESKFISENYL	VRWSSSGLPK	DIDRLHNLRA	VFTDLGSKDL	KREKISFVCQ
310	320	330	340	350	360
IVRVGRMELR	DNNTRKLTSG	LRRPFGVAVM	DVTDIINGKV	DDEDKQHFIP	FQPVAGENDF
370	380	390	400	410	420
LQTVINKVIA	AKEVNHKGQG	LWVTLKLLPG	DIHQIRKEFP	HLVDRTTAVA	RKTGFPEIIM
430	440	450	460	470	480
PGDVRNDIYV	TLVQGDFDKG	SKTTAKNVEV	TVSVYDEDGK	RLEHVIFPGA	GDEAISEYKS
490	500	510	520	530	540
VIYYQVKQPR	WFETVKVAIP	IEDVNRSHLR	FTFRHRSSQD	SKDKSEKIFA	LAFVKLMRYD
550	560	570	580	590	600
GTTLRDGEHD	LIVYKAEAKK	LEDAATYLSL	PSTKAELEEK	GHSATGKSMQ	SLGSCTISKD
610	620	630	640	650	660
SFQISTLVCS	TKLTQNVDLL	GLLKWRSNTS	LLQQNLRQLM	KVDGGEVVKF	LQDTLDALFN
670	680	690	700	710	720
IMMENSESET	FDTLVFDALV	FIIGLIADRK	FQHFNPVLET	YIKKHFSATL	AYTKLTKVLK
730	740	750	760	770	780
NYVDGAEKPG	VNEQLYKAMK	ALESIFKFIV	RSRILFNQLY	ENKGEADFVE	SLLQLFRSIN
790	800	810	820	830	840
DMMSSMSDQT	VRVKGAALKY	LPTIVNDVKL	VFDPKELSKM	FTEFILNVPM	GLLTIQKLYC
850	860	870	880	890	900
LIEIVHSDLF	TQHDCREILL	PMMTDQLKYH	LERQEDLEAC	CQLLSHILEV	LYRKDVGPTQ
910	920	930	940	950	960
RHVQIIMEKL	LRTVNRTVIS	MGRDSELIGN	FVACMTAILR	QMEDYHYAHL	IKTFGKMRTD
970	980	990	1000	1010	1020
VVDFLMETFI	MFKNLIGKNV	YPFDWVIMNM	VQNKVFLRAI	NQYADMLNKK	FLDQANFELQ
1030	1040	1050	1060	1070	1080
LWNNYFHLAV	AFLTQESLQL	ENFSSAKRAK	ILNKYGDMRR	QIGFEIRDMW	YNLGQHKIKF
1090	1100	1110	1120	1130	1140
IPEMVGPILE	MTLIPETELR	KATIPIFFDM	MQCEFHSTRS	FQMFENEIIT	KLDHEVEGGR
1150	1160	1170	1180	1190	1200
GDEQYKVLFD	KILLEHCRKH	KYLAKTGETF	VKLVVRLMER	LLDYRTIMHD	ENKENRMSCT
1210	1220	1230	1240	1250	1260
VNVLNFYKEI	EREEMYIRYL	YKLCDLHKEC	DNYTEAAYTL	LLHAKLLKWS	EDVCVAHLTQ
1270	1280	1290	1300	1310	1320
RDGYQATTQG	QLKEQLYQEI	IHYFDKGKMW	EEAIALGKEL	AEQYENEMFD	YEQLSELLKK
1330	1340	1350	1360	1370	1380
QAQFYENIVK	VIRPKPDYFA	VGYYGQGFPT	FLRGKVFIYR	GKEYERREDF	EARLLTQFPN
1390	1400	1410	1420	1430	1440
AEKMKTTSPP	GDDIKNSPGQ	YIQCFTVKPK	LDLPPKFHRP	VSEQIVSFYR	VNEVQRFEYS
1450	1460	1470	1480	1490	1500
RPIRKGEKNP	DNEFANMWIE	RTIYTTAYKL	PGILRWFEVK	SVFMVEISPL	ENAIETMQLT
1510	1520	1530	1540	1550	1560
NDKINSMVQQ	HLDDPSLPIN	PLSMLLNGIV	DPAVMGGFAN	YEKAFFTDRY	LQEHPEAHEK
1570	1580	1590	1600	1610	1620
IEKLKDLIAW	QIPFLAEGIR	IHGDKVTEAL	RPFHERMEAC	FKQLKEKVEK	EYGVRIMPSS
1630	1640	1650	1660	1670	1680
LDDRRGSRPR	SMVRSFTMPS	SSRPLSVASV	SSLSSDSTPS	RPGSDGFALE	PLLPKKMHSR
1690	1700	1710	1720	1730	1740
SQDKLDKDDL	EKEKKDKKKE	KRNSKHQEIF	EKEFKPTDIS	LQQSEAVILS	ETISPLRPQR
1750	1760	1770	1780	1790	1800
PKSQVMNVIG	SERRFSVSPS	SPSSQQTPPP	VTPRAKLSFS	MQSSLELNGM	TGADVADVPP
1810	1820	1830	1840	1850	1860
PLPLKGSVAD	YGNLMENQDL	LGSPTPPPPP	PHQRHLPPPL	PSKTPPPPPP	KTTRKQASVD

SGIVQ