Q14142
PR
Gene name |
TRIM14 (KIAA0129) |
Protein name |
Tripartite motif-containing protein 14 |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:9830 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q14142
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6JBM | X-ray | 210 A | A/B/C/D | 249-442 | PDB |
| AF-Q14142-F1 | Predicted | AlphaFoldDB |
370 variants for Q14142
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs778053648 CA5150880 |
5 | A>E | No |
ClinGen ExAC gnomAD |
|
|
CA5150881 rs754174890 |
5 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA5150877 rs767705083 |
6 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA5150876 rs759576088 |
7 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751619874 CA5150875 |
8 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs375310781 CA5150873 |
9 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375310781 CA5150874 |
9 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 11 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA374197414 rs1423746868 |
13 | R>K | No |
ClinGen gnomAD |
|
|
rs372298132 CA5150872 |
14 | S>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5150869 rs775328114 |
15 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs368291230 CA5150870 |
15 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5150868 rs375930099 |
16 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA196768757 rs925879009 |
17 | V>D | No |
ClinGen TOPMed gnomAD |
|
|
CA374197273 rs1258856156 |
19 | G>E | No |
ClinGen gnomAD |
|
| TCGA novel | 20 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA374197231 rs1316047001 |
22 | W>* | No |
ClinGen gnomAD |
|
|
CA5150866 rs778435213 |
22 | W>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771353576 CA5150865 |
23 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374197216 rs771353576 |
23 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749728288 CA5150864 |
23 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749728288 CA374197211 |
23 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771353576 CA374197217 |
23 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150860 rs781424936 |
25 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150861 rs781424936 |
25 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374197175 rs1463594388 |
26 | E>G | No |
ClinGen gnomAD |
|
|
rs751606156 CA5150858 |
29 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs766418352 CA374197128 |
30 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs766418352 CA5150857 |
30 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA5150856 rs367703741 |
31 | V>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs963726912 CA196768724 |
31 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA374197122 rs963726912 |
31 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
CA374197111 rs1197176518 |
32 | A>S | No |
ClinGen gnomAD |
|
|
rs1239003372 CA374197088 |
34 | L>F | No |
ClinGen gnomAD |
|
|
rs1291070654 CA374197076 |
35 | F>L | No |
ClinGen TOPMed |
|
|
rs911013094 CA196768714 |
37 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA196768711 rs562095803 |
38 | R>L | No |
ClinGen 1000Genomes |
|
|
CA374197026 rs1456502143 |
39 | C>* | No |
ClinGen gnomAD |
|
|
CA5150853 rs374436760 |
40 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5150852 rs760583179 |
41 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs1587983868 CA374197008 |
41 | R>L | No |
ClinGen Ensembl |
|
|
CA5150849 rs759168247 |
43 | V>E | No |
ClinGen ExAC gnomAD |
|
|
rs771643597 CA5150850 |
43 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771643597 CA374196994 |
43 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1311017219 CA374196980 |
44 | C>* | No |
ClinGen TOPMed gnomAD |
|
|
rs773737813 CA5150848 |
44 | C>R | No |
ClinGen ExAC gnomAD |
|
|
CA5150847 rs770540635 |
45 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA196768674 rs981028811 |
46 | L>F | No |
ClinGen gnomAD |
|
|
CA196768664 rs748775309 |
47 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA5150846 rs748775309 |
47 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs1404947074 CA374196935 |
48 | P>L | No |
ClinGen gnomAD |
|
|
CA374196941 rs1404947074 |
48 | P>Q | No |
ClinGen gnomAD |
|
|
rs1404947074 CA374196940 |
48 | P>R | No |
ClinGen gnomAD |
|
|
rs1444918039 CA374196902 |
51 | G>D | No |
ClinGen TOPMed |
|
|
rs1434497994 CA374196874 |
54 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1409759150 CA374196865 |
55 | G>R | No |
ClinGen TOPMed |
|
|
rs778293010 CA5150845 |
56 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs770247267 CA5150844 |
57 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs969036184 CA196768648 |
59 | G>S | No |
ClinGen gnomAD |
|
|
rs1232421515 CA374196808 |
60 | L>R | No |
ClinGen gnomAD |
|
|
CA374196802 rs542320588 |
61 | A>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA5150843 rs542320588 |
61 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs573252148 CA5150842 |
62 | L>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1354164352 CA374196764 |
65 | A>E | No |
ClinGen gnomAD |
|
|
rs559348391 CA196768636 |
65 | A>T | No |
ClinGen 1000Genomes |
|
|
CA374196753 rs1345922586 |
66 | V>L | No |
ClinGen gnomAD |
|
|
rs1322951485 CA374196740 |
67 | H>Y | No |
ClinGen gnomAD |
|
|
rs868598210 CA196768614 |
68 | V>L | No |
ClinGen gnomAD |
|
|
CA374196725 rs868598210 |
68 | V>M | No |
ClinGen gnomAD |
|
|
CA5150823 rs769126916 |
72 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA374195276 rs769126916 |
72 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs747318410 CA5150822 |
73 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
rs1233448359 CA374195266 |
73 | Q>P | No |
ClinGen gnomAD |
|
|
CA196766602 rs1008253225 |
74 | E>Q | No |
ClinGen TOPMed gnomAD |
|
|
TCGA novel CA374195239 rs1275768006 |
75 | C>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen gnomAD NCI-TCGA |
|
CA374195221 rs1365250174 |
76 | L>* | No |
ClinGen Ensembl |
|
|
rs1260529008 CA374195201 |
78 | Q>R | No |
ClinGen TOPMed |
|
|
rs1438922616 CA374195175 |
82 | K>E | No |
ClinGen gnomAD |
|
|
CA374195154 rs1325372116 |
84 | Q>H | No |
ClinGen gnomAD |
|
|
rs758650880 CA5150819 |
85 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA5150818 rs745965352 |
86 | H>L | No |
ClinGen ExAC gnomAD |
|
|
CA5150817 rs779075403 |
87 | I>F | No |
ClinGen ExAC gnomAD |
|
|
CA5150816 rs539114208 |
87 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1364576435 CA374194819 |
89 | N>D | No |
ClinGen Ensembl |
|
|
CA196766596 rs767478252 |
90 | I>M | No |
ClinGen Ensembl |
|
|
CA5150815 rs752745546 |
93 | I>R | No |
ClinGen ExAC gnomAD |
|
|
rs754776714 CA5150811 |
98 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150812 rs754776714 |
98 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374210753 rs1174631634 |
105 | E>G | No |
ClinGen TOPMed |
|
|
rs772634382 CA5150783 |
107 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1213994851 CA374210708 |
111 | L>R | No |
ClinGen gnomAD |
|
| TCGA novel | 113 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 115 | F>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1249448168 CA374210673 |
116 | T>S | No |
ClinGen gnomAD |
|
|
CA196782660 rs954595898 |
118 | L>F | No |
ClinGen gnomAD |
|
| TCGA novel | 118 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1206405698 CA374210657 |
119 | R>G | No |
ClinGen gnomAD |
|
|
rs913857379 CA196782654 |
120 | L>* | No |
ClinGen Ensembl |
|
|
CA5150775 rs746983430 |
124 | E>* | Variant assessed as Somatic; 9.239e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA374210626 rs746983430 |
124 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA374210600 rs760502317 |
127 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760502317 CA5150774 |
127 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760502317 CA5150773 |
127 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1257322623 COSM1103097 CA374210581 |
130 | K>N | endometrium Variant assessed as Somatic; 4.619e-05 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs1587959468 CA374210566 |
132 | F>L | No |
ClinGen Ensembl |
|
|
CA5150771 rs778572754 |
133 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA196782621 rs1037630548 |
134 | D>E | No |
ClinGen TOPMed |
|
|
rs753405523 CA5150769 |
137 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA374210533 rs1259192180 |
137 | T>S | No |
ClinGen gnomAD |
|
|
CA5150766 rs147144578 |
138 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA374210514 rs1264715109 |
140 | T>I | No |
ClinGen TOPMed |
|
|
rs199641111 CA196782520 |
145 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA5150765 rs768116851 |
146 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1298640776 CA374210467 |
147 | Q>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs766636819 CA5150762 |
149 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs760019112 CA5150764 |
149 | D>N | No |
ClinGen ExAC |
|
|
CA5150763 rs774806522 |
149 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs763017879 CA5150761 |
150 | S>A | No |
ClinGen ExAC gnomAD |
|
|
rs773476916 CA5150760 |
150 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 151 | C>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA374210446 rs1351160679 |
151 | C>R | No |
ClinGen gnomAD |
|
|
CA5150759 rs769819667 |
155 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA374210408 rs1474547420 |
156 | D>A | No |
ClinGen gnomAD |
|
|
CA374210392 rs1417772896 |
158 | M>T | No |
ClinGen gnomAD |
|
|
rs748233492 CA5150758 |
159 | N>S | No |
ClinGen ExAC |
|
|
CA374210374 rs1479016058 |
160 | D>E | No |
ClinGen gnomAD |
|
|
rs200179824 CA5150757 |
160 | D>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1260026798 CA374210371 |
161 | L>F | No |
ClinGen gnomAD |
|
|
CA374210353 rs1204807985 |
164 | R>G | No |
ClinGen gnomAD |
|
|
CA374210351 rs1488911453 |
164 | R>K | No |
ClinGen gnomAD |
|
|
rs771953795 CA5150756 |
165 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs745689594 CA5150755 |
167 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778625917 CA5150754 |
168 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA5150753 rs748963837 |
171 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1172392581 CA374210302 |
171 | E>Q | No |
ClinGen gnomAD |
|
|
rs375983980 CA5150751 |
172 | P>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5150749 rs752225130 |
173 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 174 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1323391671 CA374210281 |
174 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA374210268 rs1373174267 |
176 | Q>R | No |
ClinGen TOPMed |
|
|
CA196778139 rs894847983 |
180 | A>T | No |
ClinGen TOPMed |
|
|
rs780781911 CA5150730 |
182 | T>K | No |
ClinGen ExAC gnomAD |
|
|
rs780781911 CA374209681 |
182 | T>M | No |
ClinGen ExAC gnomAD |
|
|
rs766884497 CA5150727 |
185 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374209557 rs1564177774 |
188 | M>I | No |
ClinGen Ensembl |
|
|
rs750756229 CA5150725 |
190 | Q>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1191063270 CA374209491 |
191 | Q>R | No |
ClinGen TOPMed |
|
|
CA374209482 rs765395938 CA5150724 |
192 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761969969 CA5150723 |
193 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs753923320 CA5150722 |
193 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760733321 CA5150720 |
195 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA196778106 rs979915212 |
195 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
rs762688206 CA5150717 |
196 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150716 rs773012076 |
197 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150715 rs769574344 |
198 | C>R | No |
ClinGen ExAC gnomAD |
|
|
CA5150713 COSM2793293 rs572131932 |
201 | V>M | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1381151661 CA374209241 |
205 | F>S | No |
ClinGen gnomAD |
|
|
CA196778006 rs866443352 |
207 | P>S | No |
ClinGen Ensembl |
|
|
rs7467660 CA196777986 |
208 | V>A | No |
ClinGen Ensembl |
|
|
CA5150711 COSM1103095 rs149392923 |
208 | V>I | central_nervous_system endometrium Variant assessed as Somatic; 4.62e-05 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs773349976 CA196777982 |
211 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1564177597 CA374209092 |
212 | F>C | No |
ClinGen Ensembl |
|
|
CA374209111 rs1322052308 |
212 | F>L | No |
ClinGen TOPMed |
|
|
rs750770823 CA374209029 |
216 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750770823 COSM1240511 CA5150708 |
216 | V>M | oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1221659035 CA374208999 |
218 | A>V | No |
ClinGen gnomAD |
|
|
CA5150706 rs2296079 VAR_048399 |
219 | V>M | No |
ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA5150705 rs754120583 |
220 | E>V | No |
ClinGen ExAC gnomAD |
|
|
CA374208950 rs1357888041 |
221 | S>N | No |
ClinGen gnomAD |
|
|
CA374208943 rs1261379853 |
222 | T>A | No |
ClinGen TOPMed |
|
|
CA5150704 rs114314984 |
225 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs150211153 CA374208862 |
227 | L>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1175379081 CA374208856 |
228 | D>N | No |
ClinGen TOPMed |
|
|
rs1399136845 CA374208838 |
229 | I>T | No |
ClinGen gnomAD |
|
|
rs138197499 CA5150701 |
230 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs551029194 CA5150700 |
230 | R>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA374208835 rs138197499 |
230 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5150699 rs773018076 |
233 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150673 rs145652674 |
234 | S>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs376316638 CA5150672 |
235 | I>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1162458530 CA374208094 |
237 | C>F | No |
ClinGen TOPMed |
|
|
rs1412708479 CA374208052 |
239 | L>F | No |
ClinGen gnomAD |
|
|
CA374207991 rs1374561162 |
242 | P>S | No |
ClinGen gnomAD |
|
|
rs1349137457 CA374207978 |
243 | S>F | No |
ClinGen TOPMed |
|
|
CA374207964 rs1342965777 |
245 | T>P | No |
ClinGen gnomAD |
|
|
rs778055619 CA5150669 |
246 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756429394 CA5150668 |
247 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
CA5150667 rs748460318 |
248 | G>C | No |
ClinGen ExAC gnomAD |
|
|
rs1327580940 CA374207929 |
248 | G>D | No |
ClinGen TOPMed |
|
|
CA5150666 rs373336252 |
254 | S>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5150664 rs751550332 |
255 | P>H | No |
ClinGen ExAC gnomAD |
|
|
CA5150665 rs751550332 |
255 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs757198553 CA5150662 |
257 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA374207837 rs1215154305 |
258 | E>K | No |
ClinGen gnomAD |
|
|
CA5150660 rs764051742 |
259 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA374207817 rs764051742 |
259 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA196775361 rs953560026 |
261 | L>I | No |
ClinGen TOPMed |
|
|
CA374207262 rs1168931022 |
265 | Y>C | No |
ClinGen gnomAD |
|
|
CA374207263 rs1168931022 |
265 | Y>S | No |
ClinGen gnomAD |
|
|
rs946030318 CA196773028 |
266 | A>V | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 267 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770159621 CA5150625 |
268 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1007130141 CA196773019 |
268 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
rs776800341 CA5150623 |
270 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs977231855 CA196772987 |
270 | T>K | No |
ClinGen TOPMed gnomAD |
|
|
CA374207134 rs1564173010 |
271 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs768922852 CA5150622 |
272 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1251217592 CA374207097 |
273 | P>S | No |
ClinGen gnomAD |
|
|
rs1479555456 CA374207077 |
274 | D>A | No |
ClinGen gnomAD |
|
|
CA5150620 rs780414118 |
275 | T>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 275 | T>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5150621 rs747298622 |
275 | T>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA374206993 rs1232936488 |
278 | A>G | No |
ClinGen gnomAD |
|
|
rs1300711756 CA374206997 |
278 | A>S | No |
ClinGen gnomAD |
|
|
CA374206986 rs1297313917 |
279 | R>G | No |
ClinGen TOPMed |
|
|
CA374206988 rs1297313917 |
279 | R>S | No |
ClinGen TOPMed |
|
|
CA374206945 rs567268646 |
281 | R>H | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs567268646 CA196772972 |
281 | R>P | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA374206933 rs1435635573 |
282 | L>R | No |
ClinGen gnomAD |
|
|
CA374206913 rs1171933288 |
284 | A>T | No |
ClinGen gnomAD |
|
|
CA196772965 rs952554786 |
286 | R>S | No |
ClinGen TOPMed |
|
|
CA374206844 rs1183957555 |
287 | L>M | No |
ClinGen TOPMed gnomAD |
|
|
CA374206823 COSM3779469 rs752551468 |
288 | T>K | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs752551468 CA5150615 |
288 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374206805 rs1211332935 |
289 | V>A | No |
ClinGen gnomAD |
|
|
rs1025549912 CA196772940 |
289 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1277767019 CA374206792 |
290 | R>P | No |
ClinGen gnomAD |
|
|
CA5150613 rs754764863 |
291 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150611 rs765982913 |
292 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA196772908 rs371197846 |
292 | G>D | No |
ClinGen Ensembl |
|
|
rs765982913 CA196772928 |
292 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150609 rs749885404 |
295 | G>C | No |
ClinGen ExAC gnomAD |
|
|
CA5150607 rs527321964 |
297 | L>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5150605 rs761229737 |
299 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs777188169 CA5150606 |
299 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM129884 rs1385826950 CA374206689 |
300 | V>M | upper_aerodigestive_tract [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA196772865 rs1000371035 |
301 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA374206673 rs1000371035 |
301 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs761101028 CA5150603 |
301 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA374206653 rs1442701463 |
303 | L>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 304 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA196772844 rs868459773 |
304 | R>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs745969370 CA5150600 |
306 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs867934051 CA196772827 |
307 | A>V | No |
ClinGen Ensembl |
|
|
rs1268064876 CA374206573 |
310 | Q>E | No |
ClinGen gnomAD |
|
|
rs778800533 CA374206539 |
313 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778800533 CA5150598 |
313 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1291796721 CA374206533 |
313 | A>V | No |
ClinGen gnomAD |
|
|
CA374206531 rs570888057 |
314 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
CA5150597 rs570888057 |
314 | R>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA374206512 rs1327246560 |
315 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA196772816 rs552497291 |
316 | C>S | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs552497291 CA374206504 |
316 | C>Y | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA374206490 rs1587942196 |
317 | F>S | No |
ClinGen Ensembl |
|
|
CA374206478 rs1292145636 |
318 | A>P | No |
ClinGen TOPMed |
|
|
rs75264230 CA5150595 |
319 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA196772801 rs894870446 |
319 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
rs894870446 CA374206469 |
319 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1587942158 CA374206462 |
320 | G>A | No |
ClinGen Ensembl |
|
|
rs781165754 CA5150594 |
323 | Y>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374206405 rs1415456428 |
324 | W>* | No |
ClinGen gnomAD |
|
|
rs754805853 CA5150593 |
326 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746766293 CA5150592 |
328 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746766293 CA374206357 |
328 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA196772784 rs867885667 |
330 | E>* | No |
ClinGen Ensembl |
|
|
rs1190504628 CA374206310 |
332 | G>S | No |
ClinGen gnomAD |
|
|
rs749950072 CA374206291 |
333 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749950072 CA374206289 |
333 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150590 rs757984725 |
333 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757984725 CA374206299 |
333 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749950072 CA5150589 |
333 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1179848355 CA374206283 |
334 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1288257126 CA374206250 |
336 | W>L | No |
ClinGen gnomAD |
|
|
rs1052442265 CA196772762 |
337 | V>G | No |
ClinGen Ensembl |
|
|
CA374206220 rs1228113658 |
338 | G>D | No |
ClinGen gnomAD |
|
|
CA374206195 rs1587942014 |
339 | A>V | No |
ClinGen Ensembl |
|
|
rs754354608 CA5150586 |
340 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1587941995 CA374206181 |
340 | A>S | No |
ClinGen Ensembl |
|
|
rs1041029069 CA196772755 |
342 | A>G | No |
ClinGen TOPMed |
|
|
rs764667150 CA5150585 |
342 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761156214 CA5150584 |
343 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA374206114 rs1364600627 |
344 | L>F | No |
ClinGen gnomAD |
|
|
CA196772746 rs773793794 |
344 | L>R | No |
ClinGen Ensembl |
|
|
rs543677793 CA5150583 |
345 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5150582 rs767865620 |
346 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759766028 CA5150581 |
349 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs1165822710 CA374206015 |
350 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
rs868743224 CA196772719 |
353 | A>D | No |
ClinGen Ensembl |
|
|
rs770975476 CA5150579 |
353 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150578 rs749355088 |
354 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs1278598134 CA374205931 |
356 | G>V | No |
ClinGen gnomAD |
|
|
CA196772704 rs769099347 |
358 | N>H | No |
ClinGen Ensembl |
|
|
rs1246397297 CA374205905 |
358 | N>S | No |
ClinGen TOPMed |
|
|
CA5150573 rs758182900 |
359 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150574 rs758182900 |
359 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs745561512 CA5150572 |
359 | R>P | No |
ClinGen ExAC gnomAD |
|
|
rs778608776 CA5150571 |
360 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA5150570 rs756759967 |
360 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1056382273 CA196772690 |
360 | Q>R | No |
ClinGen Ensembl |
|
|
CA374205845 rs1203383211 |
361 | S>C | No |
ClinGen TOPMed |
|
|
rs369293667 CA5150569 |
363 | C>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA374205795 rs1365508065 |
364 | L>F | No |
ClinGen gnomAD |
|
|
rs1292888744 CA374205787 |
365 | K>E | No |
ClinGen gnomAD |
|
|
CA374205748 rs1442782671 |
367 | Y>H | No |
ClinGen TOPMed gnomAD |
|
|
CA374205722 rs1326593151 |
368 | D>N | No |
ClinGen gnomAD |
|
|
CA374205697 rs1428783025 |
369 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA374205685 rs1375683603 |
370 | E>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA374205627 rs756632629 |
372 | W>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150567 rs756632629 |
372 | W>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs918457484 CA196772673 |
374 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
rs753116492 CA5150566 |
375 | H>N | No |
ClinGen ExAC gnomAD |
|
|
CA374205561 rs1191169346 |
376 | D>N | No |
ClinGen gnomAD |
|
|
CA374205526 rs768063658 |
379 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150565 rs768063658 |
379 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA196772671 rs972569959 |
381 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA374205503 rs972569959 |
381 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1224317237 CA374205487 |
383 | R>Q | No |
ClinGen gnomAD |
|
|
rs774476061 CA5150563 |
383 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs1587941601 CA374205473 |
384 | P>L | No |
ClinGen Ensembl |
|
|
rs1355800803 CA374205454 |
387 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1364788103 CA374205437 |
389 | D>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1364788103 CA374205436 |
389 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1316810310 CA374205439 |
389 | D>N | No |
ClinGen TOPMed |
|
|
CA5150560 rs773217259 |
390 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA5150559 rs768581016 |
390 | R>P | No |
ClinGen ExAC gnomAD |
|
|
rs918607166 CA196772629 |
391 | L>V | No |
ClinGen gnomAD |
|
|
COSM4163152 rs775391711 CA5150557 |
392 | G>R | thyroid [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA5150556 rs771900809 |
393 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs963150604 CA196772617 |
396 | D>Y | No |
ClinGen TOPMed |
|
|
CA5150555 rs372317510 |
398 | E>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1255555000 CA374205359 |
399 | A>T | No |
ClinGen gnomAD |
|
|
CA374205345 rs1216598011 |
400 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA5150554 rs369655193 |
401 | V>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs990470173 CA196772611 |
401 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
rs990470173 CA374205338 |
401 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA374205305 rs1355900347 |
404 | F>L | No |
ClinGen gnomAD |
|
|
CA374205282 rs1393989077 |
405 | Y>C | No |
ClinGen gnomAD |
|
|
rs748765729 CA5150552 |
405 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA374205268 rs1377980051 |
406 | D>V | No |
ClinGen gnomAD |
|
|
rs1289016872 CA374205262 |
407 | V>M | No |
ClinGen gnomAD |
|
|
rs1385740517 CA374205224 |
410 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
CA374205228 rs1385740517 |
410 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
CA5150550 rs755682455 |
411 | M>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA374205214 rs1212145242 |
411 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1457147294 CA374205179 |
412 | S>R | No |
ClinGen gnomAD |
|
|
rs1175446788 CA374205143 |
415 | H>Y | No |
ClinGen TOPMed |
|
|
CA374205123 rs1422365574 |
416 | T>I | No |
ClinGen gnomAD |
|
|
rs572521028 CA5150546 |
418 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs541518442 CA5150547 |
418 | R>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA374205080 rs766523895 |
419 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150545 rs766523895 |
419 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374205071 rs1282930816 |
419 | A>V | No |
ClinGen gnomAD |
|
|
CA374205067 rs1362723186 |
420 | T>A | No |
ClinGen TOPMed |
|
|
rs201617037 CA5150543 |
420 | T>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs201617037 CA5150544 |
420 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1335380279 CA374205041 |
422 | Q>R | No |
ClinGen gnomAD |
|
|
CA5150541 rs761855637 |
425 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA374204990 rs1295874233 |
426 | Y>C | No |
ClinGen gnomAD |
|
|
CA374204988 rs1295874233 |
426 | Y>F | No |
ClinGen gnomAD |
|
|
CA5150539 rs772008221 |
427 | P>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 428 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5150537 rs774141914 |
431 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA374204928 rs1456734404 |
433 | E>V | No |
ClinGen gnomAD |
|
|
CA5150534 rs770495045 |
434 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150531 rs777555750 |
436 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5150530 rs199858943 |
437 | S>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1020373244 CA196772505 |
437 | S>N | No |
ClinGen TOPMed |
|
|
CA374204881 rs1207933405 |
439 | P>H | No |
ClinGen gnomAD |
|
|
rs1564171663 CA374204882 |
439 | P>S | No |
ClinGen Ensembl |
|
|
CA5150528 rs144459488 |
440 | R>W | No |
ClinGen 1000Genomes ExAC gnomAD |
No associated diseases with Q14142
10 regional properties for Q14142
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | B-box-type zinc finger | 19 - 61 | IPR000315 |
| domain | B30.2/SPRY domain | 249 - 442 | IPR001870 |
| domain | SPRY domain | 319 - 442 | IPR003877 |
| domain | Butyrophylin-like, SPRY domain | 265 - 282 | IPR003879-1 |
| domain | Butyrophylin-like, SPRY domain | 304 - 328 | IPR003879-2 |
| domain | Butyrophylin-like, SPRY domain | 335 - 348 | IPR003879-3 |
| domain | Butyrophylin-like, SPRY domain | 382 - 406 | IPR003879-4 |
| domain | Butyrophylin-like, SPRY domain | 413 - 431 | IPR003879-5 |
| domain | SPRY-associated | 266 - 318 | IPR006574 |
| domain | TRIM14, PRY/SPRY domain | 269 - 441 | IPR044116 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| phagocytic vesicle | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
| protein kinase binding | Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. |
| transcription coactivator activity | A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. |
| ubiquitin protein ligase activity | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. |
| zinc ion binding | Binding to a zinc ion (Zn). |
11 GO annotations of biological process
| Name | Definition |
|---|---|
| innate immune response | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. |
| negative regulation of viral transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription. |
| positive regulation of autophagy | Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. |
| positive regulation of DNA-binding transcription factor activity | Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. |
| positive regulation of I-kappaB kinase/NF-kappaB signaling | Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling. |
| positive regulation of NF-kappaB transcription factor activity | Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. |
| protein polyubiquitination | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. |
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
| regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| regulation of protein localization | Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. |
| regulation of viral entry into host cell | Any process that modulates the frequency, rate or extent of the viral entry into the host cell. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9H2S5 | RNF39 | RING finger protein 39 | Homo sapiens (Human) | PR |
| Q86UV7 | TRIM73 | Tripartite motif-containing protein 73 | Homo sapiens (Human) | PR |
| Q86XT4 | TRIM50 | E3 ubiquitin-protein ligase TRIM50 | Homo sapiens (Human) | PR |
| Q6ZMU5 | TRIM72 | Tripartite motif-containing protein 72 | Homo sapiens (Human) | PR |
| Q9UPQ4 | TRIM35 | E3 ubiquitin-protein ligase TRIM35 | Homo sapiens (Human) | PR |
| Q9BZY9 | TRIM31 | E3 ubiquitin-protein ligase TRIM31 | Homo sapiens (Human) | PR |
| Q9C029 | TRIM7 | E3 ubiquitin-protein ligase TRIM7 | Homo sapiens (Human) | PR |
| O15553 | MEFV | Pyrin | Homo sapiens (Human) | SS |
| A6NCK2 | TRIM43B | Tripartite motif-containing protein 43B | Homo sapiens (Human) | PR |
| Q8N9V2 | TRIML1 | Probable E3 ubiquitin-protein ligase TRIML1 | Homo sapiens (Human) | PR |
| P19474 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 | Homo sapiens (Human) | PR |
| A6NK02 | TRIM75 | Tripartite motif-containing protein 75 | Homo sapiens (Human) | PR |
| Q5EBN2 | TRIM61 | Putative tripartite motif-containing protein 61 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGAATGSRT | PGRSELVEGC | GWRCPEHGDR | VAELFCRRCR | RCVCALCPVL | GAHRGHPVGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ALEAAVHVQK | LSQECLKQLA | IKKQQHIDNI | TQIEDATEKL | KANAESSKTW | LKGKFTELRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLDEEEALAK | KFIDKNTQLT | LQVYREQADS | CREQLDIMND | LSNRVWSISQ | EPDPVQRLQA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YTATEQEMQQ | QMSLGELCHP | VPLSFEPVKS | FFKGLVEAVE | STLQTPLDIR | LKESINCQLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DPSSTKPGTL | LKTSPSPERS | LLLKYARTPT | LDPDTMHARL | RLSADRLTVR | CGLLGSLGPV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PVLRFDALWQ | VLARDCFATG | RHYWEVDVQE | AGAGWWVGAA | YASLRRRGAS | AAARLGCNRQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SWCLKRYDLE | YWAFHDGQRS | RLRPRDDLDR | LGVFLDYEAG | VLAFYDVTGG | MSHLHTFRAT |
| 430 | 440 | ||||
| FQEPLYPALR | LWEGAISIPR | LP |