Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q10RI7

Entry ID Method Resolution Chain Position Source
AF-Q10RI7-F1 Predicted AlphaFoldDB

No variants for Q10RI7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q10RI7

No associated diseases with Q10RI7

No regional properties for Q10RI7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q10RI7

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasmic stress granule A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
nuclear envelope The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

4 GO annotations of biological process

Name Definition
poly(A)+ mRNA export from nucleus The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
response to abscisic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

20 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2TBP1 DDX25 ATP-dependent RNA helicase DDX25 Bos taurus (Bovine) PR
Q3ZBV2 DDX19A ATP-dependent RNA helicase DDX19A Bos taurus (Bovine) SS
Q9UHL0 DDX25 ATP-dependent RNA helicase DDX25 Homo sapiens (Human) PR
Q9NUU7 DDX19A ATP-dependent RNA helicase DDX19A Homo sapiens (Human) PR
Q9UMR2 DDX19B ATP-dependent RNA helicase DDX19B Homo sapiens (Human) PR
Q61655 Ddx19a ATP-dependent RNA helicase DDX19A Mus musculus (Mouse) SS
Q9QY15 Ddx25 ATP-dependent RNA helicase DDX25 Mus musculus (Mouse) PR
Q10I26 EIF4A3B Eukaryotic initiation factor 4A-III homolog B Oryza sativa subsp japonica (Rice) PR
Q5VNM3 EIF4A3A Eukaryotic initiation factor 4A-III homolog A Oryza sativa subsp japonica (Rice) PR
Q2R1M8 Os11g0599500 DEAD-box ATP-dependent RNA helicase 52C Oryza sativa subsp. japonica (Rice) SS
Q6Z4K6 PL10B DEAD-box ATP-dependent RNA helicase 52B Oryza sativa subsp. japonica (Rice) SS
Q75HJ0 PL10A DEAD-box ATP-dependent RNA helicase 37 Oryza sativa subsp. japonica (Rice) SS
Q5QMN3 Os01g0197200 DEAD-box ATP-dependent RNA helicase 20 Oryza sativa subsp japonica (Rice) PR
Q0E2Z7 Os02g0201900 DEAD-box ATP-dependent RNA helicase 41 Oryza sativa subsp japonica (Rice) PR
Q5JK84 AIP2 DEAD-box ATP-dependent RNA helicase 15 Oryza sativa subsp japonica (Rice) PR
Q5Z6G5 Os06g0697200 DEAD-box ATP-dependent RNA helicase 35B Oryza sativa subsp japonica (Rice) PR
Q0JM17 AIP1 DEAD-box ATP-dependent RNA helicase 56 Oryza sativa subsp japonica (Rice) PR
Q5N7W4 Os01g0911100 DEAD-box ATP-dependent RNA helicase 30 Oryza sativa subsp japonica (Rice) PR
Q0E3X4 Os02g0150100 DEAD-box ATP-dependent RNA helicase 35A Oryza sativa subsp japonica (Rice) PR
Q93ZG7 RH38 DEAD-box ATP-dependent RNA helicase 38 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MADGGKPPTP EKKSWADVEE EEEAKAKAAA AAEAASSSSS NEPAVDAQAK QIEALSLSVP
70 80 90 100 110 120
EEHGGSGGGG DDQGPPLLDD SDESQIQAVT SGGTVYESAA AFEDLKLTPE LLKGLHDEMG
130 140 150 160 170 180
FSRPSKIQAV TLPMILTPPY KDLIAQAHNG SGKTTCFVLG MLSRVDPNRK VTQAICICPT
190 200 210 220 230 240
RELAQQNKSV LMRMGKFTGI TCACAIPPAQ KDYVPIAKMP KITDQVVIGT SGTLMKWINH
250 260 270 280 290 300
KKILTNDIKI LVFDEADHML AEDGFRSDSE RIMRDIQRSA GGCQVLLFSA TFNERVKDFV
310 320 330 340 350 360
TRVIKDGNQI FVKKEELTLE KVKQYKVQVP DERAKIAVIK DKIFEFGQKV GQVIIFVRTK
370 380 390 400 410 420
QSTKDVHNAL TLEDYVCSSI QGSLDQSERE KIIQEFKNGY TKVLISTDVL ARGFDQAQVN
430 440 450 460 470 480
LVINYDMPIK FGTRDEPDYE VYLHRIGRAG RFGRKGAVFN LLCGETDNTV MRKIETYFQH
490 500
NVPEVRNWQS EEDFERALKD AGLVE