Q0WR59
PR
Gene name |
At5g10020 (T31P16.10, T31P16_9) |
Protein name |
Probable inactive receptor kinase At5g10020 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G10020 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0WR59
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0WR59-F1 | Predicted | AlphaFoldDB |
64 variants for Q0WR59
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13976434 | 55 | T>I | No | 1000Genomes | |
| tmp_5_3134053_G_T | 180 | K>N | No | 1000Genomes | |
| tmp_5_3134152_A_C | 213 | L>F | No | 1000Genomes | |
| tmp_5_3134160_A_C | 216 | E>A | No | 1000Genomes | |
| tmp_5_3134181_A_G | 223 | N>S | No | 1000Genomes | |
| ENSVATH06946503 | 241 | S>N | No | 1000Genomes | |
| ENSVATH06946503 | 241 | S>T | No | 1000Genomes | |
| ENSVATH06946505 | 242 | E>A | No | 1000Genomes | |
| ENSVATH03042284 | 246 | G>S | No | 1000Genomes | |
| ENSVATH03042286 | 262 | N>S | No | 1000Genomes | |
| tmp_5_3134340_T_C | 276 | I>T | No | 1000Genomes | |
| ENSVATH06946507 | 309 | F>L | No | 1000Genomes | |
| tmp_5_3134684_C_A | 328 | S>Y | No | 1000Genomes | |
| tmp_5_3134701_G_A | 334 | D>N | No | 1000Genomes | |
| tmp_5_3134734_A_G | 345 | I>V | No | 1000Genomes | |
| ENSVATH00614183 | 356 | V>M | No | 1000Genomes | |
| ENSVATH06946510 | 361 | K>N | No | 1000Genomes | |
| ENSVATH06946511 | 364 | A>V | No | 1000Genomes | |
| ENSVATH03042299 | 377 | S>W | No | 1000Genomes | |
| tmp_5_3134836_A_G | 379 | S>G | No | 1000Genomes | |
| ENSVATH13976565 | 383 | F>C | No | 1000Genomes | |
| tmp_5_3134974_G_A | 425 | G>S | No | 1000Genomes | |
| ENSVATH06946512 | 430 | S>T | No | 1000Genomes | |
| ENSVATH03042300 | 433 | T>S | No | 1000Genomes | |
| ENSVATH06946513 | 436 | S>R | No | 1000Genomes | |
| ENSVATH13976567 | 448 | E>A | No | 1000Genomes | |
| ENSVATH03042301 | 483 | M>L | No | 1000Genomes | |
| ENSVATH03042302 | 486 | G>E | No | 1000Genomes | |
| tmp_5_3135251_G_A | 517 | G>D | No | 1000Genomes | |
| ENSVATH03042303 | 537 | P>S | No | 1000Genomes | |
| ENSVATH10675477 | 541 | V>M | No | 1000Genomes | |
| tmp_5_3135334_G_A | 545 | V>M | No | 1000Genomes | |
| ENSVATH06946515 | 549 | D>N | No | 1000Genomes | |
| ENSVATH06946516 | 586 | D>E | No | 1000Genomes | |
| ENSVATH10675478 | 620 | F>I | No | 1000Genomes | |
| ENSVATH10675479 | 621 | A>V | No | 1000Genomes | |
| ENSVATH06946517 | 625 | T>R | No | 1000Genomes | |
| tmp_5_3135594_C_A | 631 | H>Q | No | 1000Genomes | |
| ENSVATH00614189 | 632 | G>V | No | 1000Genomes | |
| tmp_5_3135595_G_T | 632 | G>W | No | 1000Genomes | |
| ENSVATH03042307 | 664 | Q>E | No | 1000Genomes | |
| tmp_5_3135697_T_G | 666 | S>A | No | 1000Genomes | |
| ENSVATH06946519 | 679 | A>P | No | 1000Genomes | |
| ENSVATH03042309 | 699 | A>V | No | 1000Genomes | |
| ENSVATH10675480 | 712 | Y>C | No | 1000Genomes | |
| ENSVATH13976568 | 717 | G>R | No | 1000Genomes | |
| tmp_5_3135895_C_T | 732 | R>C | No | 1000Genomes | |
| tmp_5_3135908_A_G | 736 | Q>R | No | 1000Genomes | |
| tmp_5_3136113_G_C | 804 | R>S | No | 1000Genomes | |
| tmp_5_3136145_A_T | 815 | K>I | No | 1000Genomes | |
| ENSVATH13976570 | 817 | G>S | No | 1000Genomes | |
| ENSVATH10675482 | 826 | P>L | No | 1000Genomes | |
| tmp_5_3136184_G_A | 828 | R>Q | No | 1000Genomes | |
| tmp_5_3136237_C_G | 846 | L>V | No | 1000Genomes | |
| ENSVATH10675483 | 910 | R>L | No | 1000Genomes | |
| ENSVATH10675483 | 910 | R>Q | No | 1000Genomes | |
| tmp_5_3136588_T_A | 929 | I>K | No | 1000Genomes | |
| ENSVATH06946520 | 933 | S>R | No | 1000Genomes | |
| ENSVATH13976571 | 947 | K>I | No | 1000Genomes | |
| tmp_5_3136656_C_T | 952 | L>F | No | 1000Genomes | |
| ENSVATH03042316 | 958 | A>V | No | 1000Genomes | |
| ENSVATH13976573 | 1011 | E>A | No | 1000Genomes | |
| ENSVATH00614191 | 1028 | L>V | No | 1000Genomes | |
| ENSVATH06946521 | 1048 | A>D | No | 1000Genomes |
No associated diseases with Q0WR59
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein kinase activity | Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P0C0K6 | EPHB6 | Ephrin type-B receptor 6 | Pan troglodytes (Chimpanzee) | SS |
| Q38SD2 | LRRK1 | Leucine-rich repeat serine/threonine-protein kinase 1 | Homo sapiens (Human) | EV |
| P55144 | Tyro3 | Tyrosine-protein kinase receptor TYRO3 | Mus musculus (Mouse) | SS |
| Q61006 | Musk | Muscle, skeletal receptor tyrosine-protein kinase | Mus musculus (Mouse) | SS |
| Q00993 | Axl | Tyrosine-protein kinase receptor UFO | Mus musculus (Mouse) | PR |
| Q60805 | Mertk | Tyrosine-protein kinase Mer | Mus musculus (Mouse) | SS |
| Q3UFB7 | Ntrk1 | High affinity nerve growth factor receptor | Mus musculus (Mouse) | SS |
| P09581 | Csf1r | Macrophage colony-stimulating factor 1 receptor | Mus musculus (Mouse) | SS |
| P21803 | Fgfr2 | Fibroblast growth factor receptor 2 | Mus musculus (Mouse) | SS |
| P16092 | Fgfr1 | Fibroblast growth factor receptor 1 | Mus musculus (Mouse) | SS |
| Q03142 | Fgfr4 | Fibroblast growth factor receptor 4 | Mus musculus (Mouse) | PR |
| P05622 | Pdgfrb | Platelet-derived growth factor receptor beta | Mus musculus (Mouse) | SS |
| Q00342 | Flt3 | Receptor-type tyrosine-protein kinase FLT3 | Mus musculus (Mouse) | SS |
| Q61851 | Fgfr3 | Fibroblast growth factor receptor 3 | Mus musculus (Mouse) | PR |
| Q9TZM3 | lrk-1 | Leucine-rich repeat serine/threonine-protein kinase 1 | Caenorhabditis elegans | SS |
| O12990 | jak1 | Tyrosine-protein kinase JAK1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSHFLTFCFL | SLLLLLHGAN | AVTETELRSL | LEFRKGIRDE | TSHQRISWSD | TSSLTDPSTC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PNDWPGISCD | PETGSIIAIN | LDRRGLSGEL | KFSTLSGLTR | LRNLSLSGNS | FSGRVVPSLG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GISSLQHLDL | SDNGFYGPIP | GRISELWSLN | HLNLSSNKFE | GGFPSGFRNL | QQLRSLDLHK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NEIWGDVGEI | FTELKNVEFV | DLSCNRFNGG | LSLPMENISS | ISNTLRHLNL | SHNALNGKFF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SEESIGSFKN | LEIVDLENNQ | INGELPHFGS | QPSLRILKLA | RNELFGLVPQ | ELLQSSIPLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELDLSRNGFT | GSISEINSST | LTMLNLSSNG | LSGDLPSSFK | SCSVIDLSGN | TFSGDVSVVQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KWEATPDVLD | LSSNNLSGSL | PNFTSAFSRL | SVLSIRNNSV | SGSLPSLWGD | SQFSVIDLSS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NKFSGFIPVS | FFTFASLRSL | NLSRNNLEGP | IPFRGSRASE | LLVLNSYPQM | ELLDLSTNSL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TGMLPGDIGT | MEKIKVLNLA | NNKLSGELPS | DLNKLSGLLF | LDLSNNTFKG | QIPNKLPSQM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VGFNVSYNDL | SGIIPEDLRS | YPPSSFYPGN | SKLSLPGRIP | ADSSGDLSLP | GKKHHSKLSI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RIAIIVASVG | AAIMILFVLF | AYHRTQLKDF | HGRNRFTDQA | TTRDTKFGRS | SRPSLFNFSS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NVEQQSSSLS | FSNDHLLTAN | SRSLSGIPGC | EAEISEQGAP | ATSAPTNLLD | DYPAASGRKS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| SSGGSPLSSS | PRFSDQPVML | DVYSPDRLAG | ELFFLDVSLK | LTAEELSRAP | AEVLGRSSHG |
| 790 | 800 | 810 | 820 | 830 | 840 |
| TLYKATLDNG | HMLTVKWLRV | GLVRHKKDFA | REAKKIGSLK | HPNIVPLRAY | YWGPREQERL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| LLSDYLRGES | LAMHLYETTP | RRYSPMSFSQ | RLKVAVEVAQ | CLLYLHDRAM | PHGNLKPTNI |
| 910 | 920 | 930 | 940 | 950 | 960 |
| ILSSPDNTVR | ITDYCVHRLM | TPSGVAEQIL | NMSALGYSAP | ELSSASKPIP | TLKSDVYAFG |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| VILMELLTRR | SAGDIISGQT | GAVDLTDWVR | LCDQEGRRMD | CIDRDIAGGE | EFSKGMEDAL |
| 1030 | 1040 | ||||
| AVAIRCILSV | NERPNIRQVL | DHLTSISA |