Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0WNR6

Entry ID Method Resolution Chain Position Source
AF-Q0WNR6-F1 Predicted AlphaFoldDB

29 variants for Q0WNR6

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_28712453_T_A 16 T>S No 1000Genomes
ENSVATH14484819 20 V>A No 1000Genomes
tmp_1_28712438_C_G 21 E>Q No 1000Genomes
ENSVATH13819433 41 P>S No 1000Genomes
ENSVATH13819432 43 D>Y No 1000Genomes
ENSVATH05155528 44 T>S No 1000Genomes
ENSVATH05155527 52 V>I No 1000Genomes
ENSVATH14484818 57 A>T No 1000Genomes
ENSVATH05155526 90 T>S No 1000Genomes
ENSVATH13819431 91 S>G No 1000Genomes
tmp_1_28712204_T_C 99 T>A No 1000Genomes
ENSVATH05155525 100 L>F No 1000Genomes
tmp_1_28712167_G_A 111 S>L No 1000Genomes
ENSVATH14484817 114 H>Y No 1000Genomes
ENSVATH13819430 117 E>Q No 1000Genomes
ENSVATH05155524 118 E>G No 1000Genomes
tmp_1_28712125_G_T 125 T>K No 1000Genomes
tmp_1_28712107_G_A 131 A>V No 1000Genomes
ENSVATH13819429 158 E>Q No 1000Genomes
tmp_1_28711869_C_A 165 A>S No 1000Genomes
ENSVATH14484800 267 R>K No 1000Genomes
tmp_1_28710350_G_A 270 A>V No 1000Genomes
ENSVATH05155500 275 M>V No 1000Genomes
tmp_1_28710023_A_T 322 M>K No 1000Genomes
ENSVATH13819412 325 V>D No 1000Genomes
ENSVATH13819413 325 V>F No 1000Genomes
tmp_1_28709687_G_A 343 P>L No 1000Genomes
tmp_1_28709446_A_T 362 F>I No 1000Genomes
tmp_1_28709009_G_C 408 P>R No 1000Genomes

No associated diseases with Q0WNR6

2 regional properties for Q0WNR6

Type Name Position InterPro Accession
domain ARID DNA-binding domain 142 - 234 IPR001606
domain Alpha crystallin/Hsp20 domain 336 - 434 IPR002068

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q99856 ARID3A AT-rich interactive domain-containing protein 3A Homo sapiens (Human) SS
Q8BM75 Arid5b AT-rich interactive domain-containing protein 5B Mus musculus (Mouse) PR
Q62431 Arid3a AT-rich interactive domain-containing protein 3A Mus musculus (Mouse) PR
O02326 cfi-1 AT-rich interactive domain-containing protein cfi-1 Caenorhabditis elegans PR
C0SUW7 ARID6 AT-rich interactive domain-containing protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MMADTEMQEQ DVPSGTKGVV EEPSELEKDL NSIERPKSPV PEDTTHTLDS DVHLSDAPIA
70 80 90 100 110 120
NQIEANEEVG GQNSVDGRNG DVDQSEKKIT SDGGQEETTL GESNPLKGDP SSPHVPEESV
130 140 150 160 170 180
KKWKTWLLSD AEAREVDEAG APQDQEAFIK EVEAFNKENF LEFKAPKFYG QPLNCLKLWR
190 200 210 220 230 240
AVIKLGGYDV VTTSKLWRQV GESFHPPKTC TTVSWTFRIF YEKALLEYEK HLRQNGELNL
250 260 270 280 290 300
PGSASLPSSG IEKEASSHQA SGSGRTRRDA AARAMQGWHS QRLLGSGEVT EPIVKEKGLN
310 320 330 340 350 360
STPKQKNLKN IGVQKQKTTT GMDLVFSHES EKQSTAEVID VGPPADWVKI NVRETKDCFE
370 380 390 400 410 420
IFALVPGLLR EEVRVQSDPA GRLVIAGQPE QLDNPWGITP FKKVVNFPAR IDPLHTSAVV
430
SLHGRLFVRV PFEQ