Q0II87
Gene name |
TFAM |
Protein name |
Transcription factor A, mitochondrial |
Names |
mtTFA |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:510059 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0II87
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0II87-F1 | Predicted | AlphaFoldDB |
No variants for Q0II87
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0II87 | |||||
No associated diseases with Q0II87
No regional properties for Q0II87
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q0II87 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial nucleoid | The region of a mitochondrion to which the DNA is confined. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| chromatin binding | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
| mitochondrial promoter sequence-specific DNA binding | Binding to a DNA region that controls the transcription of the mitochondrial DNA. |
| mitochondrial transcription factor activity | Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial transcription | The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| transcription initiation at mitochondrial promoter | A transcription initiation process that takes place at a promoter on the mitochondrial chromosome. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q32L34 | HMGB4 | High mobility group protein B4 | Bos taurus (Bovine) | PR |
| P17480 | UBTF | Nucleolar transcription factor 1 | Homo sapiens (Human) | EV |
| Q00059 | TFAM | Transcription factor A, mitochondrial | Homo sapiens (Human) | PR |
| Q3USZ2 | Ubtfl1 | Upstream-binding factor 1-like protein 1 | Mus musculus (Mouse) | PR |
| P25976 | Ubtf | Nucleolar transcription factor 1 | Mus musculus (Mouse) | PR |
| P40630 | Tfam | Transcription factor A, mitochondrial | Mus musculus (Mouse) | PR |
| Q5D144 | TFAM | Transcription factor A, mitochondrial | Sus scrofa (Pig) | PR |
| P25977 | Ubtf | Nucleolar transcription factor 1 | Rattus norvegicus (Rat) | PR |
| Q9T012 | HMGB13 | High mobility group B protein 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SUP7 | HMGB6 | High mobility group B protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALLRGVWGV | LNALGKSGAD | LCAGCGSRLR | YPFSFAYVPK | WFSSSLSGYP | KKPMTSYVRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SKEQLPIFKA | QNPDAKNSEL | IKKIAKLWRE | LPDSEKKIYE | DAYRADWQVY | KEEINRIQEQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LTPSQMVSLE | KEIMQKRLKK | KALIKKRELT | MLGKPKRPRS | AYNIFIAERF | QEARDGTSQV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KLKAINENWK | NLSNSQKQVY | IQLAKDDKIR | YYNEMKSWEE | QMMEVGREDL | IRRSIKYPAK |
| NDPEKF |