Q0E3X4

PR
Gene name
Os02g0150100 (LOC_Os02g05660, OSJNBa0050G13.7)
Protein name
DEAD-box ATP-dependent RNA helicase 35A
Names
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4328308
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

69-154 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0E3X4

Entry ID Method Resolution Chain Position Source
AF-Q0E3X4-F1 Predicted AlphaFoldDB

No variants for Q0E3X4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0E3X4

No associated diseases with Q0E3X4

6 regional properties for Q0E3X4

Type Name Position InterPro Accession
domain Helicase, C-terminal 408 - 568 IPR001650
domain Zinc finger, CCHC-type 585 - 601 IPR001878
domain DEAD/DEAH box helicase domain 206 - 385 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 201 - 412 IPR014001
domain RNA helicase, DEAD-box type, Q motif 182 - 210 IPR014014
domain DDX41, DEAD-box helicase domain 193 - 398 IPR044113

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9V3C0 abs ATP-dependent RNA helicase abstrakt Drosophila melanogaster (Fruit fly) PR
Q9UJV9 DDX41 Probable ATP-dependent RNA helicase DDX41 Homo sapiens (Human) PR
Q91VN6 Ddx41 Probable ATP-dependent RNA helicase DDX41 Mus musculus (Mouse) PR
Q5Z6G5 Os06g0697200 DEAD-box ATP-dependent RNA helicase 35B Oryza sativa subsp japonica (Rice) PR
Q10I26 EIF4A3B Eukaryotic initiation factor 4A-III homolog B Oryza sativa subsp japonica (Rice) PR
Q5VNM3 EIF4A3A Eukaryotic initiation factor 4A-III homolog A Oryza sativa subsp japonica (Rice) PR
Q2R1M8 Os11g0599500 DEAD-box ATP-dependent RNA helicase 52C Oryza sativa subsp. japonica (Rice) SS
Q6Z4K6 PL10B DEAD-box ATP-dependent RNA helicase 52B Oryza sativa subsp. japonica (Rice) SS
Q75HJ0 PL10A DEAD-box ATP-dependent RNA helicase 37 Oryza sativa subsp. japonica (Rice) SS
Q10RI7 Os03g0158200 DEAD-box ATP-dependent RNA helicase 38 Oryza sativa subsp japonica (Rice) PR
Q5QMN3 Os01g0197200 DEAD-box ATP-dependent RNA helicase 20 Oryza sativa subsp japonica (Rice) PR
Q0E2Z7 Os02g0201900 DEAD-box ATP-dependent RNA helicase 41 Oryza sativa subsp japonica (Rice) PR
Q5N7W4 Os01g0911100 DEAD-box ATP-dependent RNA helicase 30 Oryza sativa subsp japonica (Rice) PR
Q5JK84 AIP2 DEAD-box ATP-dependent RNA helicase 15 Oryza sativa subsp japonica (Rice) PR
Q0JM17 AIP1 DEAD-box ATP-dependent RNA helicase 56 Oryza sativa subsp japonica (Rice) PR
Q9LU46 RH35 DEAD-box ATP-dependent RNA helicase 35 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZB4 RH43 Putative DEAD-box ATP-dependent RNA helicase 43 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAAATASSPA TAAAANSDDE DNYEEYIPVA KRRAMEADRL RRLRLSKPAP PSSSAAEAAS
70 80 90 100 110 120
DLPPPPPPPP NQPSAGGGGG GLEASAKPSL LVKATQLKRA APEVTHTEQL IMQEKEMIEH
130 140 150 160 170 180
LSDRKTLMSV RELAKGITYS DPLKTGWKPP LRLRRMPRAK ADELRRKWHI LVDGDDVPPP
190 200 210 220 230 240
ARDFRDLRLP EPMLRKLREK GIVQPTPIQV QGLPVVLSGR DMIGIAFTGS GKTLVFVLPL
250 260 270 280 290 300
IMVALQEEMM MPIVPGEGPF GMIICPSREL AKQTYDVIEQ FLVPLKEAGY PEIRPLLCIG
310 320 330 340 350 360
GVDMRAQLDV VKKGVHIVVA TPGRLKDLLA KKKMNLDNCR YLTLDEADRL VDLGFEDDIR
370 380 390 400 410 420
EVFDHFKAQR QTLLFSATMP KKIQNFAKSA LVKPVIVNVG RAGAANLDVI QEVEYVKEDA
430 440 450 460 470 480
RIIYLLECLQ KTPPPVLVFC ENKADVDYIH EYLLLKGVEA VAIHGGKDQE ERENAIEFFK
490 500 510 520 530 540
NGKKDVLVAT DVASKGLDFP DIQHVINYDM PAEIENYVHR IGRTGRCGKT GIATTFINKN
550 560 570 580 590 600
QTETTLLDLK HLLKEAKQRI PPVLAELNDP LEDEETMAKE SGVKGCAYCG GLGHRVTDCP
610 620
KLEHQKSMAI AGSRRDYYGG GGYRGEI