Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0E2Z7

Entry ID Method Resolution Chain Position Source
AF-Q0E2Z7-F1 Predicted AlphaFoldDB

No variants for Q0E2Z7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0E2Z7

No associated diseases with Q0E2Z7

3 regional properties for Q0E2Z7

Type Name Position InterPro Accession
domain Protein kinase domain 128 - 409 IPR000719
active_site Serine/threonine-protein kinase, active site 271 - 283 IPR008271
binding_site Protein kinase, ATP binding site 134 - 157 IPR017441

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

23 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2NL08 DDX55 ATP-dependent RNA helicase DDX55 Bos taurus (Bovine) PR
P17844 DDX5 Probable ATP-dependent RNA helicase DDX5 Homo sapiens (Human) PR
Q8NHQ9 DDX55 ATP-dependent RNA helicase DDX55 Homo sapiens (Human) PR
Q99MJ9 Ddx50 ATP-dependent RNA helicase DDX50 Mus musculus (Mouse) PR
Q61656 Ddx5 Probable ATP-dependent RNA helicase DDX5 Mus musculus (Mouse) PR
Q501J6 Ddx17 Probable ATP-dependent RNA helicase DDX17 Mus musculus (Mouse) PR
Q6ZPL9 Ddx55 ATP-dependent RNA helicase DDX55 Mus musculus (Mouse) PR
Q5QMN3 Os01g0197200 DEAD-box ATP-dependent RNA helicase 20 Oryza sativa subsp japonica (Rice) PR
Q5JK84 AIP2 DEAD-box ATP-dependent RNA helicase 15 Oryza sativa subsp japonica (Rice) PR
Q5VNM3 EIF4A3A Eukaryotic initiation factor 4A-III homolog A Oryza sativa subsp japonica (Rice) PR
Q10I26 EIF4A3B Eukaryotic initiation factor 4A-III homolog B Oryza sativa subsp japonica (Rice) PR
Q75HJ0 PL10A DEAD-box ATP-dependent RNA helicase 37 Oryza sativa subsp. japonica (Rice) SS
Q6Z4K6 PL10B DEAD-box ATP-dependent RNA helicase 52B Oryza sativa subsp. japonica (Rice) SS
Q2R1M8 Os11g0599500 DEAD-box ATP-dependent RNA helicase 52C Oryza sativa subsp. japonica (Rice) SS
Q10RI7 Os03g0158200 DEAD-box ATP-dependent RNA helicase 38 Oryza sativa subsp japonica (Rice) PR
Q5Z6G5 Os06g0697200 DEAD-box ATP-dependent RNA helicase 35B Oryza sativa subsp japonica (Rice) PR
Q0JM17 AIP1 DEAD-box ATP-dependent RNA helicase 56 Oryza sativa subsp japonica (Rice) PR
Q5N7W4 Os01g0911100 DEAD-box ATP-dependent RNA helicase 30 Oryza sativa subsp japonica (Rice) PR
Q0E3X4 Os02g0150100 DEAD-box ATP-dependent RNA helicase 35A Oryza sativa subsp japonica (Rice) PR
Q9C718 RH20 DEAD-box ATP-dependent RNA helicase 20 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H136 RH14 DEAD-box ATP-dependent RNA helicase 14 Arabidopsis thaliana (Mouse-ear cress) PR
Q56X76 RH39 DEAD-box ATP-dependent RNA helicase 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q8W4R3 RH30 DEAD-box ATP-dependent RNA helicase 30 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEQEENHSAD HLSAQPGNGN ELEESSVKER CFEQREALVG EPRCVICGRY GEYICDQTDD
70 80 90 100 110 120
DICSVECKTI LLSKLSAETR PVVKAAKRVN LPVGDESFCI RDENFPKIPS MHDGQIASLR
130 140 150 160 170 180
SKLDICVKGE DVPDPIMCFS SSGLPEKLVL NLEAAGYVMP TPVQMQVIPS SICNRSLLVS
190 200 210 220 230 240
ADTGSGKTAS FLVPIIAHCS HVRSERCTDK QGPLAIVLAP TRELCLQVEE QAKVLGKGLP
250 260 270 280 290 300
FKTALVVGGD PLAQQIYRIE NGIELIVGTP GRLIDLLMKH NVDLNKVDVF VLDEVDCLLE
310 320 330 340 350 360
RGFRDQVMQI FQALSHPQVM MFSATVNSEV EKMSNSLAKN AIHISCGNPS RPNKSVKQVV
370 380 390 400 410 420
IWVESKQKKQ KIFEIMTSKQ HFKPPAVVFV SSRIGADLLS EAITVATGLK VVSIHGDKTM
430 440 450 460 470 480
NERRESLRRF LTGEVSVVVC TGVLGRGMDL LKVRQVILFD MPNSIDEYVH QVGRASRMGV
490 500 510 520 530
EGMAIVFVNE EDRNLFRELV QILKTAGAPI PRELANSKYT TGIPLGGGKK RKLKSR