Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0D622

Entry ID Method Resolution Chain Position Source
AF-Q0D622-F1 Predicted AlphaFoldDB

No variants for Q0D622

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0D622

No associated diseases with Q0D622

5 regional properties for Q0D622

Type Name Position InterPro Accession
domain Helicase, C-terminal 309 - 462 IPR001650
domain DEAD/DEAH box helicase domain 105 - 276 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 99 - 304 IPR014001
domain RNA helicase, DEAD-box type, Q motif 80 - 108 IPR014014
domain Domain of unknown function DUF4217 463 - 529 IPR025313

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P20448 HCA4 ATP-dependent RNA helicase HCA4 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q6Z2Z4 Os02g0146600 Eukaryotic initiation factor 4A-3 Oryza sativa subsp japonica (Rice) PR
Q7Y183 RH10 DEAD-box ATP-dependent RNA helicase 10 Oryza sativa subsp japonica (Rice) PR
Q0DBS1 Os06g0535100 Putative DEAD-box ATP-dependent RNA helicase 51 Oryza sativa subsp japonica (Rice) PR
P35683 Os06g0701100 Eukaryotic initiation factor 4A-1 Oryza sativa subsp japonica (Rice) PR
Q8L4E9 Os07g0633500 DEAD-box ATP-dependent RNA helicase 36 Oryza sativa subsp japonica (Rice) PR
Q5K5B6 Os07g0647900 DEAD-box ATP-dependent RNA helicase 57 Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MRRPRSRGAA KQTRLREADE IRLLEAWIDA GKPARGTRPP PLSKSSSSPA DTAAAKRGAK
70 80 90 100 110 120
GAGGVPSKAA GEHPEYGACA RFDELPLSNK TKDGLRKAGY TEMSEIQRAA LPHALCGRDV
130 140 150 160 170 180
LGAAKTGSGK TLAFVIPVLE KLYRERWGPE DGVGCIVLSP NKDLAGQIFN VFQKVGKLHG
190 200 210 220 230 240
FSAACIVGNR KGLDEEKAVI NNMNILVCTP GRLLQHMGET TNFDCSQIQQ ILVIDEADQV
250 260 270 280 290 300
LDKNFQEQVD NVVSQLPKVR QTLLFSATQT KSVKDLARVS LKDPEYISVH EEATTATPDT
310 320 330 340 350 360
LEQYAMIVPL EQKLNMLWSF IKRHLKSRIL VFLSSVKQVK FVYEVFKKLR PGISLRCMHG
370 380 390 400 410 420
RMKYEVQQAI VAEFKEGHSV LFSTDIFARG LDIEDVDWVV QVDCPENIAL YIHRVGRTAR
430 440 450 460 470 480
YNKRGKALIF LCPEEEKMLE KLKAAESKIP IHIKKPNTEQ LQQISQNIAS VLVQYPNLQQ
490 500 510 520 530 540
LGKRAFVTYL KSVYLQSDKE VFDLSRFSME NFAAYAASLG LPVTPKIRFV SHKKNVPKKY
550 560 570 580 590 600
MGDIDVKRMK RSSKPEVIEI NPQAKSNLIE DDGDYDILYP KEQQTDVNMA DGLDDVLYPK
610 620 630 640 650 660
VSTADTNNEP EKVTQLGNKS VKKKKLKINV HRPLGTRVKF DDEGHTIPPF ASIAEEVGSG
670 680 690 700 710 720
DVIDKDKISQ RYAEMLREMQ EHDKEDKLEH KRILREKKLQ KKLKLKRKRN EEMDAGSENS
730 740 750 760 770
GSESDRDQRT ASKGKKRYFN SDDEEGSKDA AKDGDVLAQQ EALALKLLSK MHS