Q08DZ3
Gene name |
ELMOD2 |
Protein name |
ELMO domain-containing protein 2 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:515278 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q08DZ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q08DZ3-F1 | Predicted | AlphaFoldDB |
41 variants for Q08DZ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs475229008 | 13 | F>L | No | EVA | |
| rs456826313 | 33 | R>Q | No | EVA | |
| rs443869331 | 48 | E>G | No | EVA | |
| rs476885458 | 53 | Y>S | No | EVA | |
| rs451928014 | 55 | K>T | No | EVA | |
| rs433145774 | 57 | K>N | No | EVA | |
| rs439562143 | 243 | Q>R | No | EVA | |
| rs476017697 | 246 | C>* | No | EVA | |
| rs442965909 | 246 | C>F | No | EVA | |
| rs432642274 | 247 | Y>F | No | EVA | |
| rs457580202 | 247 | Y>N | No | EVA | |
| rs465694231 | 248 | L>F | No | EVA | |
| rs434790473 | 249 | V>E | No | EVA | |
| rs453313596 | 249 | V>L | No | EVA | |
| rs449299467 | 250 | Y>F | No | EVA | |
| rs469148558 | 251 | E>D | No | EVA | |
| rs482409943 | 251 | E>K | No | EVA | |
| rs482409943 | 251 | E>Q | No | EVA | |
| rs458691744 | 253 | D>E | No | EVA | |
| rs477092545 | 253 | D>N | No | EVA | |
| rs477092545 | 253 | D>Y | No | EVA | |
| rs446374027 | 254 | K>T | No | EVA | |
| rs461010898 | 256 | W>C | No | EVA | |
| rs479216226 | 256 | W>L | No | EVA | |
| rs442485022 | 258 | E>G | No | EVA | |
| rs475593429 | 259 | E>K | No | EVA | |
| rs439061426 | 260 | K>N | No | EVA | |
| rs463902229 | 260 | K>T | No | EVA | |
| rs472056140 | 261 | P>A | No | EVA | |
| rs453630245 | 262 | E>K | No | EVA | |
| rs434728886 | 263 | S>I | No | EVA | |
| rs434728886 | 263 | S>N | No | EVA | |
| rs474196896 | 263 | S>R | No | EVA | |
| rs437257217 | 265 | M>I | No | EVA | |
| rs455765155 | 265 | M>L | No | EVA | |
| rs470331125 | 266 | Y>F | No | EVA | |
| rs450564426 | 268 | N>Y | No | EVA | |
| rs465051924 | 281 | L>R | No | EVA | |
| rs446710220 | 289 | L>I | No | EVA | |
| rs432935131 | 291 | L>F | No | EVA | |
| rs479799033 | 294 | I>S | No | EVA |
No associated diseases with Q08DZ3
1 regional properties for Q08DZ3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ELMO domain | 113 - 282 | IPR006816 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTPase activator activity | Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of GTPase activity | Any process that activates or increases the activity of a GTPase. |
| regulation of defense response to virus | Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFIALWEFFY | GHFFRFWMKW | LLRQMTGKCE | LQRIFDTYVG | AQRTHRIENS | LTYSKNKVLQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KATLVVQSEV | DRCVEDIMKE | KNINPEKDAS | FKICMKACLL | QISGYKQLYL | DVESVRKKPY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DSDNLQHEKL | LIKLWNLLMP | TKKLKARISK | QWADIGFQGD | DPKTDFRGMG | ILGLINLVYF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SENYTSEAHQ | ILSRSNHPKL | GYSYAIVGIN | LTEMAYSLLK | SEALKFHLYN | FVPGIPTMEH |
| 250 | 260 | 270 | 280 | 290 | |
| FHQFYCYLVY | EFDKFWFEEK | PESIMYFNVY | REKFHEKIKG | LLLDCNVSLT | LKI |