Q06567

PR
Gene name
MCP2
Protein name
ABC1 family protein MCP2
Names
MDM10-complementing protein 2, MIOREX complex component 13, Mitochondrial organization of gene expression protein 13
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YLR253W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q06567

Entry ID Method Resolution Chain Position Source
AF-Q06567-F1 Predicted AlphaFoldDB

2 variants for Q06567

Variant ID(s) Position Change Description Diseaes Association Provenance
s12-642857 77 T>A No SGRP
s12-643916 430 I>V No SGRP

No associated diseases with Q06567

2 regional properties for Q06567

Type Name Position InterPro Accession
domain ABC1 atypical kinase-like domain 148 - 406 IPR004147
domain ADCK1-like domain 147 - 408 IPR045307

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
  • Mitochondrion inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of mitochondrial membrane The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
lipid homeostasis Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q86TW2 ADCK1 AarF domain-containing protein kinase 1 Homo sapiens (Human) SS
O04212 At2g40090 Putative ABC1 protein At2g40090 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MMTKAFFNKL PFEVFRRYVR TGKSIPQRSP RTRKSLLVGG TIASAVVLYN FNDTFHDSVK
70 80 90 100 110 120
HTALTTKRIA VVTQATTRCF YHYKRALNKS YENKKEREVA LNKCHKMCAL ITLHALRSNG
130 140 150 160 170 180
GIYIKLGQHI GAMTYLLPKE WTDTMIPLQD HCPESTYEEI DELFKEDLGT SIEDMFLEFN
190 200 210 220 230 240
KTPIGVASLA QVHVAKLKNS DGKGSSVAVK CQHPSLKEFI PLDVMLTRTV FELLDVFFPD
250 260 270 280 290 300
YPLTWLGDEL QSSIYVELNF TKEAENAEKT RHYFSKFKKQ TALKIPKVIE SHKRILIMEY
310 320 330 340 350 360
VGGKRLDDLE YIDSHGISRS EVSSCLSHIF NNMIFTPNVG IHCDPHGGNL AIRSVKPAKD
370 380 390 400 410 420
NGYHNFEIVL FDHGLYRYPS TRTRRLYAKF WLSLLFDKDQ TKMKKYAKGF ANITDEQFPL
430 440 450 460 470 480
LAAAITGRSI DAALNYDIST SRTQEEMDVM ANGILEGTLL SDLMSILSRI PRVVLLILKT
490 500 510 520 530 540
NDLTRHLDEC LQNPLGPERT FLIMTQYCAK TVYDEKVERI NSEYARWSIK WMWENLTNWI
550 560
VYERRINQLY FYDFVLWWKK FIPKTWLSS