Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q01526

Entry ID Method Resolution Chain Position Source
AF-Q01526-F1 Predicted AlphaFoldDB

No variants for Q01526

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q01526

No associated diseases with Q01526

4 regional properties for Q01526

Type Name Position InterPro Accession
domain Protein kinase domain 36 - 294 IPR000719
active_site Serine/threonine-protein kinase, active site 153 - 165 IPR008271
binding_site Protein kinase, ATP binding site 42 - 65 IPR017441
domain Serine/threonine-protein kinase 10, catalytic domain 23 - 314 IPR042743

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
protein-containing complex binding Binding to a macromolecular complex.

4 GO annotations of biological process

Name Definition
negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
protein localization Any process in which a protein is transported to, or maintained in, a specific location.
regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P49106 GRF1 14-3-3-like protein GF14-6 Zea mays (Maize) PR
Q7XTE8 GF14B 14-3-3-like protein GF14-B Oryza sativa subsp japonica (Rice) PR
Q96450 GF14A 14-3-3-like protein A Glycine max (Soybean) (Glycine hispida) PR
P42645 GRF5 14-3-3-like protein GF14 upsilon Arabidopsis thaliana (Mouse-ear cress) PR
Q96300 GRF7 14-3-3-like protein GF14 nu Arabidopsis thaliana (Mouse-ear cress) PR
P42644 GRF3 14-3-3-like protein GF14 psi Arabidopsis thaliana (Mouse-ear cress) PR
P42652 TFT4 14-3-3 protein 4 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MASAELSREE NVYMAKLAEQ AERYEEMVEF MEKVAKTVDS EELTVEERNL LSVAYKNVIG
70 80 90 100 110 120
ARRASWRIIS SIEQKEEGRG NEDRVTLIKD YRGKIETELT KICDGILKLL ESHLVPSSTA
130 140 150 160 170 180
PESKVFYLKM KGDYYRYLAE FKTGAERKDA AENTMVAYKA AQDIALAELA PTHPIRLGLA
190 200 210 220 230 240
LNFSVFYYEI LNSPDRACSL AKQAFDEAIS ELDTLSEESY KDSTLIMQLL HDNLTLWTSD
250 260
ISEDPAEEIR EAPKHDLSEG Q