P97041

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
KEGG Pathway
lil:LA_0178
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-103 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P97041

Entry ID Method Resolution Chain Position Source
AF-P97041-F1 Predicted AlphaFoldDB

No variants for P97041

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P97041

No associated diseases with P97041

2 regional properties for P97041

Type Name Position InterPro Accession
domain Membrane insertase YidC/Oxa/ALB, C-terminal 421 - 614 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 423 - 615 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

2 GO annotations of biological process

Name Definition
protein insertion into membrane The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDRQTRLFL ALILSMGIWM GVNYFFFPNT STKKNTETKQ TQSDKTSENT KQQITSGKTK
70 80 90 100 110 120
ESNSADPVVQ KEKITPFDTK KSFIVTDSYI VEFSSLGGKI SKFYMKDFTG PNGELIQVAR
130 140 150 160 170 180
KNPETVVVDG KSYQAVELSR DKGFDFNFSD SLVEISDSPW NYIQFSLTED KINHSISFSA
190 200 210 220 230 240
VSPDRSYQLK KEFRFYPSEN YFKLSISIIN FSKEKLSFAS QKNVRYLRTF GSLGPYPKDR
250 260 270 280 290 300
PLSDRDTANF FRFYYLGGSF QDTLDGSSSV GFWSSVGNFF TGNSGTDESF SIKTDKESGV
310 320 330 340 350 360
DFAGTGSRYF IAVADPLDHK PHGIVLDNRP KNESGAVLVY DNILLNPGEN YNLDFASYIG
370 380 390 400 410 420
IRESEGMAFK NPELDPSQSK NSPFVGLSSD LNKSFNQGIT TPFRNGIIWI LKQIYRFTIP
430 440 450 460 470 480
NYGWSIIIFA ILFKLVFYPL NQKQADSMKK MQELSPQLKT INEKFANDPK MRQQKTMELY
490 500 510 520 530 540
KKNNVNPVGG CLPMVIQIPI FIALYTAFSD TIDLWNSPFL WVKDLSEPDV IWTSPAIPYF
550 560 570 580 590 600
TQTGIGLNLL ALLMVGTQVF QTRMTSVSMD PNQKMLMYVM PVMMLYIFWN MPSGVTLYWT
610 620
FQNVLSIGQQ WITNHLKKTE EKKKAKV